ATE406436T1 - Konstrukt aus kultivierten zellen mit spheroiden von kultivierten tierzellen und verwendung davon - Google Patents
Konstrukt aus kultivierten zellen mit spheroiden von kultivierten tierzellen und verwendung davonInfo
- Publication number
- ATE406436T1 ATE406436T1 AT02755656T AT02755656T ATE406436T1 AT E406436 T1 ATE406436 T1 AT E406436T1 AT 02755656 T AT02755656 T AT 02755656T AT 02755656 T AT02755656 T AT 02755656T AT E406436 T1 ATE406436 T1 AT E406436T1
- Authority
- AT
- Austria
- Prior art keywords
- cultured
- cell
- spheroids
- cultivated
- construct
- Prior art date
Links
- 210000004102 animal cell Anatomy 0.000 title 1
- 210000004748 cultured cell Anatomy 0.000 title 1
- 210000004738 parenchymal cell Anatomy 0.000 abstract 3
- 210000002889 endothelial cell Anatomy 0.000 abstract 1
- 210000002950 fibroblast Anatomy 0.000 abstract 1
- 229920001477 hydrophilic polymer Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/067—Hepatocytes
- C12N5/0671—Three-dimensional culture, tissue culture or organ culture; Encapsulated cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/14—Coculture with; Conditioned medium produced by hepatocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/28—Vascular endothelial cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/30—Synthetic polymers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/30—Synthetic polymers
- C12N2533/40—Polyhydroxyacids, e.g. polymers of glycolic or lactic acid (PGA, PLA, PLGA); Bioresorbable polymers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2535/00—Supports or coatings for cell culture characterised by topography
- C12N2535/10—Patterned coating
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001226293 | 2001-07-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE406436T1 true ATE406436T1 (de) | 2008-09-15 |
Family
ID=19059133
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02755656T ATE406436T1 (de) | 2001-07-26 | 2002-07-25 | Konstrukt aus kultivierten zellen mit spheroiden von kultivierten tierzellen und verwendung davon |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US7470424B2 (de) |
| EP (2) | EP1428871B1 (de) |
| JP (1) | JP4111446B2 (de) |
| KR (1) | KR100675533B1 (de) |
| CN (1) | CN1798832B (de) |
| AT (1) | ATE406436T1 (de) |
| CA (1) | CA2454807C (de) |
| DE (2) | DE60228594D1 (de) |
| WO (1) | WO2003010302A1 (de) |
Families Citing this family (58)
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|---|---|---|---|---|
| EP1448053A4 (de) * | 2001-10-02 | 2005-03-09 | Becton Dickinson Co | Proliferation und differenzierung von stammzellen mittels extrazellulärer matrix und anderen molekülen |
| WO2004069988A1 (ja) * | 2003-02-06 | 2004-08-19 | Cellseed Inc. | 高密度細胞アレイ用基板、製造法、及びその利用方法 |
| EP1602383B1 (de) | 2003-02-06 | 2015-05-27 | Cellseed Inc. | Zellblätter zur bildung der äusseren hornhaut sowie verfahren zu deren herstellung und verwendung |
| AU2003207288A1 (en) * | 2003-02-06 | 2004-08-30 | Cellseed Inc. | Anterior ocular-associated cell sheet, three-dimensional construct and process for producing the same |
| JP4649935B2 (ja) * | 2004-02-02 | 2011-03-16 | コニカミノルタホールディングス株式会社 | インクジェットプリンタ |
| WO2005081970A2 (en) | 2004-02-24 | 2005-09-09 | The Curators Of The University Of Missouri | Self-assembling cell aggregates and methods of making engineered tissue using the same |
| EP1859817A4 (de) | 2005-02-28 | 2012-11-07 | Cellseed Inc | Gezüchtete zellplatte, verfahren zu ihrer herstellung und verfahren zur wiederherstellung von gewebe unter verwendung der platte |
| WO2006093151A1 (ja) * | 2005-02-28 | 2006-09-08 | Cellseed Inc. | 培養細胞シート、製造方法及びその利用方法 |
| AU2006250079B2 (en) * | 2005-05-24 | 2012-05-31 | The Regents Of The University Of California | Microscale micropatterned engineered in vitor tissue |
| EP1788077B8 (de) * | 2005-11-18 | 2016-10-19 | LifeScan, Inc. | Methode zur Herstellung von Zellmassen |
| AU2013202489B2 (en) * | 2005-11-18 | 2016-03-03 | Lifescan, Inc. | A method for creating cell clusters |
| JP5070565B2 (ja) | 2006-05-29 | 2012-11-14 | 大日本印刷株式会社 | 細胞培養用基板 |
| US20090203536A1 (en) * | 2006-06-06 | 2009-08-13 | Vermette Patrick | Assay supports comprising a peg support, said support attached from a peg solution in cloud point (theta solvent) conditions |
| JP5261920B2 (ja) | 2006-11-10 | 2013-08-14 | 大日本印刷株式会社 | 細胞を用いた試験法および試験用キット |
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| JP5583312B2 (ja) * | 2007-02-20 | 2014-09-03 | 富士フイルム株式会社 | 組織体形成用基材、組織体形成キット、それを用いた組織体形成法、及び該組織体形成法により形成された三次元組織体 |
| WO2009050965A1 (ja) * | 2007-10-19 | 2009-04-23 | Japan As Represented By General Director Of Agency Of National Center For Child Health And Development | 細胞凍結物固定化基材及び初代肝細胞培養ツール、並びに初代肝細胞培養ツールの製造方法 |
| WO2009072590A1 (ja) * | 2007-12-06 | 2009-06-11 | Tokyo University Of Science Educational Foundation Administrative Organization | 分岐ポリアルキレングリコール誘導体、感光性組成物、架橋体及び基板 |
| AU2009271223B2 (en) | 2008-06-24 | 2013-05-16 | The Curators Of The University Of Missouri | Self-assembling multicellular bodies and methods of producing a three-dimensional biological structure using the same |
| KR101005874B1 (ko) * | 2008-08-27 | 2011-01-06 | 한길토건(주) | 강재 재활용이 가능한 암파쇄 방호시설의 공법 |
| EP2348099B1 (de) * | 2008-10-14 | 2017-07-05 | CellSeed Inc. | Temperaturreaktives zellkultursubstrat und verfahren zu seiner herstellung |
| JP5496488B2 (ja) * | 2008-10-22 | 2014-05-21 | 学校法人東京女子医科大学 | 細胞パターン回収ツール |
| WO2010059583A1 (en) * | 2008-11-21 | 2010-05-27 | Corning Incorporated | Spaced projection substrates and devices for cell culture |
| US20100166822A1 (en) * | 2008-12-31 | 2010-07-01 | Howmedica Osteonics Corp. | Adhesive cartilage implant |
| JP2010233538A (ja) * | 2009-03-31 | 2010-10-21 | Trans Parent:Kk | 基質代謝物の評価方法 |
| AU2010233169A1 (en) | 2009-04-09 | 2011-11-03 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Cellular seeding and co-culture of a three dimensional fibroblast construct |
| HUP0900819A2 (en) * | 2009-05-05 | 2011-01-28 | Pecsi Tudomanyegyetem | Lung tissue culture |
| US8481303B2 (en) | 2009-10-12 | 2013-07-09 | Corning Incorporated | Microfluidic device for cell culture |
| WO2011110722A1 (es) * | 2010-03-12 | 2011-09-15 | Fundación Progreso Y Salud | Método para la proliferación "in vitro" de células procedentes de tejidos de origen endodérmico |
| CN101955595B (zh) * | 2010-08-11 | 2012-01-04 | 东南大学 | 在多种材料表面制备化学微图案引导细胞定点生长的方法 |
| WO2012048170A2 (en) * | 2010-10-06 | 2012-04-12 | Massachusetts Institute Of Technology | Humanized animals via tissue engineering and uses therefor |
| CN103917640A (zh) | 2011-07-25 | 2014-07-09 | 赛图公司 | 用于形成三维多细胞集群的方法和装置 |
| CA2878404A1 (en) | 2012-07-10 | 2014-01-16 | The Trustees Of The University Of Pennsylvania | Biomaterials for enhanced implant-host integration |
| WO2014050139A1 (ja) | 2012-09-27 | 2014-04-03 | 株式会社クラレ | サイトカインがチトクロムｐ４５０の代謝能に及ぼす影響を評価する方法および薬剤のスクリーニング方法 |
| US10221230B2 (en) | 2013-02-25 | 2019-03-05 | Ohio State Innovation Foundation | HER-1, HER-3 and IGF-1R compositions and uses thereof |
| WO2014143998A1 (en) * | 2013-03-15 | 2014-09-18 | The Broad Institute | Systems and methods for culturing epithelial cells |
| US9790465B2 (en) | 2013-04-30 | 2017-10-17 | Corning Incorporated | Spheroid cell culture well article and methods thereof |
| JP6122817B2 (ja) * | 2014-03-26 | 2017-04-26 | 株式会社Ｓｃｒｅｅｎホールディングス | スフェロイドの評価方法およびスフェロイド評価装置 |
| KR101647793B1 (ko) * | 2014-09-02 | 2016-08-12 | 충남대학교산학협력단 | 온도 감응성 글리콜 키토산 유도체를 이용한 스페로이드 형성용 배양 용기 및 이를 이용한 스페로이드 형성 방법 |
| CN107109339B (zh) | 2014-10-29 | 2021-07-02 | 康宁股份有限公司 | 灌注生物反应器平台 |
| EP3212761A1 (de) | 2014-10-29 | 2017-09-06 | Corning Incorporated | Mikrovertiefungsentwurf und -herstellung zur erzeugung von zellkulturaggregaten |
| SG11201703493SA (en) | 2014-10-29 | 2017-05-30 | Corning Inc | Cell culture insert |
| CN104630148B (zh) * | 2015-01-19 | 2017-06-06 | 西安交通大学 | 一种基于水凝胶微孔板的细胞球原位制备方法 |
| CN104894051A (zh) * | 2015-05-27 | 2015-09-09 | 成都易创思生物科技有限公司 | 一种新型的细胞培养方法 |
| US11338065B2 (en) | 2015-10-08 | 2022-05-24 | Massachusetts Institute Of Technology | In situ expansion of engineered devices for regeneration |
| KR20180104646A (ko) | 2016-01-07 | 2018-09-21 | 비.지. 네게브 테크놀로지즈 앤드 애플리케이션스 리미티드, 엣 벤-구리온 유니버시티 | 면역관용 반응을 구축하기 위한 조성물 및 방법 |
| WO2018066953A1 (ko) * | 2016-10-07 | 2018-04-12 | 울산과학기술원 | 다공성막을 이용한 현적 세포 배양 기기, 이의 제조 방법, 이를 이용한 현적 세포 배양 방법, 및 현적 세포 배양 자동화 장치 |
| US11857970B2 (en) | 2017-07-14 | 2024-01-02 | Corning Incorporated | Cell culture vessel |
| JP7195302B2 (ja) | 2017-07-14 | 2022-12-23 | コーニング インコーポレイテッド | ３ｄ培養のための細胞培養容器及び３ｄ細胞の培養方法 |
| PL3652290T3 (pl) | 2017-07-14 | 2022-08-22 | Corning Incorporated | Naczynia do hodowli komórkowej 3d do ręcznej lub automatycznej zmiany pożywek |
| US11767499B2 (en) | 2017-07-14 | 2023-09-26 | Corning Incorporated | Cell culture vessel |
| WO2019060790A1 (en) * | 2017-09-22 | 2019-03-28 | Lifenet Health | PLATE-BASED HEPATOCYTES AND PREPARATION AND USES THEREOF |
| EP3794107A1 (de) * | 2018-05-16 | 2021-03-24 | Institut National de la Santé et de la Recherche Médicale (INSERM) | Verfahren zur kultivierung von proliferativen hepatozyten |
| US11912968B2 (en) | 2018-07-13 | 2024-02-27 | Corning Incorporated | Microcavity dishes with sidewall including liquid medium delivery surface |
| CN111065725B (zh) | 2018-07-13 | 2024-03-29 | 康宁股份有限公司 | 包括具有互联的壁的微板的流体装置 |
| WO2020013845A1 (en) | 2018-07-13 | 2020-01-16 | Corning Incorporated | Cell culture vessels with stabilizer devices |
| KR20210070648A (ko) * | 2019-12-05 | 2021-06-15 | 한국화학연구원 | 세포 비접착성 peg 고분자 기판 상에 형성된 심근세포 스페로이드 및 이의 제조방법 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2545100B1 (fr) * | 1983-04-29 | 1985-12-20 | Inst Nat Sante Rech Med | Procede d'obtention de cultures d'hepatocytes humains, les cultures obtenues et leurs applications biologiques et biochimiques |
| US5037969A (en) | 1986-07-03 | 1991-08-06 | Takeda Chemical Industries, Ltd. | Glycosyl derivatives and use thereof |
| JPH0751061B2 (ja) | 1989-06-03 | 1995-06-05 | 鐘淵化学工業株式会社 | 細胞の配列制御用具の製法 |
| DE3938632C1 (en) * | 1989-11-21 | 1991-03-14 | Adelbert Prof. Dr.Dr. 8046 Garching De Bacher | Culturing living animal cells - using natural or synthetic polymer substrate vacuum deposition coated with e.g. nitride of Gp=III element |
| EP0529751A1 (de) * | 1991-08-09 | 1993-03-03 | W.R. Grace & Co.-Conn. | Zellkulturträger und -testmaterial |
| US5776748A (en) * | 1993-10-04 | 1998-07-07 | President And Fellows Of Harvard College | Method of formation of microstamped patterns on plates for adhesion of cells and other biological materials, devices and uses therefor |
| JP2609073B2 (ja) | 1994-10-26 | 1997-05-14 | 鐘淵化学工業株式会社 | 細胞の配列制御用具および細胞の配列制御法 |
| ES2185769T3 (es) | 1995-04-14 | 2003-05-01 | Kazunori Kataoka | Oxidos de polietileno con un resto sacarido en un extremo y un grupo funcional diferente en el otro extremo y procedimientos de produccion de los mismos. |
| US5925720A (en) | 1995-04-19 | 1999-07-20 | Kazunori Kataoka | Heterotelechelic block copolymers and process for producing the same |
| AU726749B2 (en) | 1995-08-10 | 2000-11-16 | Kazunori Kataoka | Block polymer having functional groups on its both ends |
| WO1998051785A1 (en) * | 1997-05-14 | 1998-11-19 | The General Hospital Corporation | Co-cultivation of cells in a micropatterned configuration |
| JP3077628B2 (ja) * | 1997-05-27 | 2000-08-14 | 日本電気株式会社 | 細胞毒性試験方法 |
| JP2973976B2 (ja) | 1997-06-23 | 1999-11-08 | 日本電気株式会社 | 接着性細胞を用いた毒性試験方法 |
-
2002
- 2002-07-25 DE DE60228594T patent/DE60228594D1/de not_active Expired - Lifetime
- 2002-07-25 KR KR1020047000851A patent/KR100675533B1/ko not_active Expired - Fee Related
- 2002-07-25 AT AT02755656T patent/ATE406436T1/de not_active IP Right Cessation
- 2002-07-25 CN CN028148428A patent/CN1798832B/zh not_active Expired - Fee Related
- 2002-07-25 EP EP02755656A patent/EP1428871B1/de not_active Expired - Lifetime
- 2002-07-25 US US10/484,839 patent/US7470424B2/en not_active Expired - Fee Related
- 2002-07-25 DE DE60236974T patent/DE60236974D1/de not_active Expired - Lifetime
- 2002-07-25 WO PCT/JP2002/007539 patent/WO2003010302A1/ja not_active Ceased
- 2002-07-25 CA CA2454807A patent/CA2454807C/en not_active Expired - Fee Related
- 2002-07-25 EP EP08005978A patent/EP1939280B1/de not_active Expired - Lifetime
- 2002-07-25 JP JP2003515653A patent/JP4111446B2/ja not_active Expired - Fee Related
-
2008
- 2008-09-08 US US12/230,916 patent/US7691369B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP4111446B2 (ja) | 2008-07-02 |
| CN1798832B (zh) | 2010-04-28 |
| KR100675533B1 (ko) | 2007-01-29 |
| CA2454807C (en) | 2012-09-18 |
| CN1798832A (zh) | 2006-07-05 |
| WO2003010302A1 (en) | 2003-02-06 |
| EP1428871A4 (de) | 2004-11-24 |
| EP1939280A1 (de) | 2008-07-02 |
| US20090011504A1 (en) | 2009-01-08 |
| EP1939280B1 (de) | 2010-07-07 |
| JPWO2003010302A1 (ja) | 2005-06-02 |
| DE60228594D1 (de) | 2008-10-09 |
| KR20040025700A (ko) | 2004-03-24 |
| EP1428871B1 (de) | 2008-08-27 |
| US7470424B2 (en) | 2008-12-30 |
| US7691369B2 (en) | 2010-04-06 |
| DE60236974D1 (de) | 2010-08-19 |
| US20040197907A1 (en) | 2004-10-07 |
| CA2454807A1 (en) | 2003-02-06 |
| EP1428871A1 (de) | 2004-06-16 |
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