ATE407698T1 - Zusammensetzungen und verfahren zur behandlung von entzündlicher darmerkrankung - Google Patents

Zusammensetzungen und verfahren zur behandlung von entzündlicher darmerkrankung

Info

Publication number
ATE407698T1
ATE407698T1 AT04750581T AT04750581T ATE407698T1 AT E407698 T1 ATE407698 T1 AT E407698T1 AT 04750581 T AT04750581 T AT 04750581T AT 04750581 T AT04750581 T AT 04750581T AT E407698 T1 ATE407698 T1 AT E407698T1
Authority
AT
Austria
Prior art keywords
compositions
methods
inflammatory bowel
bowel disease
treating inflammatory
Prior art date
Application number
AT04750581T
Other languages
English (en)
Inventor
Lesley Pickford
Christopher Bebbington
Geoffrey Yarranton
David King
Original Assignee
Medarex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medarex Inc filed Critical Medarex Inc
Application granted granted Critical
Publication of ATE407698T1 publication Critical patent/ATE407698T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT04750581T 2003-04-23 2004-04-23 Zusammensetzungen und verfahren zur behandlung von entzündlicher darmerkrankung ATE407698T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US46515503P 2003-04-23 2003-04-23

Publications (1)

Publication Number Publication Date
ATE407698T1 true ATE407698T1 (de) 2008-09-15

Family

ID=33311000

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04750581T ATE407698T1 (de) 2003-04-23 2004-04-23 Zusammensetzungen und verfahren zur behandlung von entzündlicher darmerkrankung

Country Status (21)

Country Link
US (2) US7939076B2 (de)
EP (1) EP1631312B1 (de)
JP (1) JP4628357B2 (de)
KR (1) KR100817351B1 (de)
CN (2) CN101318019B (de)
AT (1) ATE407698T1 (de)
AU (1) AU2004232362C1 (de)
BR (1) BRPI0410495A (de)
CA (2) CA2823468A1 (de)
DE (1) DE602004016499D1 (de)
DK (1) DK1631312T3 (de)
ES (1) ES2313039T3 (de)
IL (1) IL171356A (de)
MX (1) MXPA05011409A (de)
NZ (1) NZ542866A (de)
PL (1) PL1631312T3 (de)
PT (1) PT1631312E (de)
SG (1) SG173919A1 (de)
SI (1) SI1631312T1 (de)
WO (1) WO2004093908A2 (de)
ZA (1) ZA200508390B (de)

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EP1631590B1 (de) * 2003-04-23 2011-07-27 Medarex, Inc. Humanisierte antikörper gegen interferon-alpha-rezeptor-1 (ifnar-1)
US9107864B2 (en) 2004-06-07 2015-08-18 Qu Biologics Inc. Tissue targeted antigenic activation of the immune response to treat cancers
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KR101166901B1 (ko) 2010-04-16 2012-07-19 송영완 임플란트용 주입기
AU2011261323A1 (en) * 2010-06-04 2013-01-24 The Brigham And Women's Hospital, Inc. Treatment of inflammatory disorders
RU2581922C2 (ru) * 2010-07-26 2016-04-20 Кью Байолоджикс Инк. Иммуногенные противовоспалительные композиции
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EP3904502A3 (de) 2013-02-04 2022-02-23 Seres Therapeutics, Inc. Zusammensetzungen und verfahren
US11185562B2 (en) 2013-02-04 2021-11-30 Seres Therapeutics, Inc. Compositions and methods for inhibition of pathogenic bacterial growth
HK1220326A1 (zh) 2013-03-15 2017-05-05 Seres Therapeutics, Inc. 基於网络微生物组成和方法
MX367109B (es) 2013-11-25 2019-08-05 Seres Therapeutics Inc Composiciones bacterianas sinergicas y sus metodos de produccion y usos.
WO2015095241A2 (en) 2013-12-16 2015-06-25 Seres Health, Inc. Bacterial compositions and methods of use thereof for treatment of immune system disorders
EP3137108A4 (de) 2014-05-02 2017-09-27 Qu Biologics Inc Antimikrobielle immunmodulation
EP3179985A1 (de) 2014-08-14 2017-06-21 Brown University Zusammensetzungen zur stabilisierung und ausgabe von proteinen
WO2016100301A1 (en) 2014-12-15 2016-06-23 The Brigham And Women's Hospital, Inc. Use of cadherin-11 antagonists to treat obesity-associated conditions and other metabolic disorders
AU2017290389B2 (en) 2016-07-01 2024-09-26 Resolve Therapeutics, Llc Optimized binuclease fusions and methods
US11136399B2 (en) 2016-07-14 2021-10-05 Institute Of Biophysics, Chinese Academy Of Sciences Type I interferon receptor antibody and use thereof
WO2018220237A1 (en) * 2017-06-02 2018-12-06 Goodgut Sl Grape skin for use in the treatment of dysbiosis
AU2018318132B2 (en) 2017-08-14 2025-06-26 Seres Therapeutics, Inc. Compositions and methods for treating cholestatic disease
US10947295B2 (en) 2017-08-22 2021-03-16 Sanabio, Llc Heterodimers of soluble interferon receptors and uses thereof
EP3703720A1 (de) 2017-10-30 2020-09-09 Seres Therapeutics, Inc. Zusammensetzungen und verfahren zur behandlung von antibiotika-resistenz
CN112056275B (zh) * 2020-09-27 2022-05-10 澎立生物医药技术(上海)有限公司 一种肠粘膜炎动物模型及其构建方法和应用

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Also Published As

Publication number Publication date
AU2004232362C1 (en) 2008-05-29
ZA200508390B (en) 2006-06-28
US7939076B2 (en) 2011-05-10
EP1631312B1 (de) 2008-09-10
PL1631312T3 (pl) 2009-02-27
AU2004232362B2 (en) 2007-09-06
CN101318019A (zh) 2008-12-10
JP2006524703A (ja) 2006-11-02
KR100817351B1 (ko) 2008-03-26
AU2004232362A1 (en) 2004-11-04
CN100409897C (zh) 2008-08-13
MXPA05011409A (es) 2005-12-12
ES2313039T3 (es) 2009-03-01
JP4628357B2 (ja) 2011-02-09
NZ542866A (en) 2009-07-31
US20050152901A1 (en) 2005-07-14
WO2004093908A2 (en) 2004-11-04
WO2004093908A3 (en) 2005-06-02
IL171356A (en) 2010-11-30
EP1631312A2 (de) 2006-03-08
CN101318019B (zh) 2012-08-29
PT1631312E (pt) 2008-12-22
BRPI0410495A (pt) 2006-06-13
SI1631312T1 (sl) 2009-02-28
DK1631312T3 (da) 2009-01-19
CA2522957A1 (en) 2004-11-04
DE602004016499D1 (de) 2008-10-23
US8828393B2 (en) 2014-09-09
CN1777444A (zh) 2006-05-24
US20110165158A1 (en) 2011-07-07
CA2823468A1 (en) 2004-11-04
CA2522957C (en) 2013-10-22
HK1082200A1 (en) 2006-06-02
SG173919A1 (en) 2011-09-29
KR20060015531A (ko) 2006-02-17

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