ATE407937T1 - Rutheniumkomplexe mit antikrebswirkung - Google Patents

Rutheniumkomplexe mit antikrebswirkung

Info

Publication number: ATE407937T1
Authority: AT; Austria
Prior art keywords: cancer effect; ruthenium complexes; ruthenium; cancer; formula
Prior art date: 2002-07-05

Application number

AT03762788T

Other languages

English (en)

Inventor

Peter Sadler

Lainez Rafael Fernandez

Abraba Habtemariam

Michael Melchart

Duncan Jodrell

Original Assignee

Univ Edinburgh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-07-05

Filing date

2003-07-04

Publication date

2008-09-15

2003-07-04 Application filed by Univ Edinburgh filed Critical Univ Edinburgh

2008-09-15 Application granted granted Critical

2008-09-15 Publication of ATE407937T1 publication Critical patent/ATE407937T1/de

Links

KJTLSVCANCCWHF-UHFFFAOYSA-N Ruthenium Chemical class [Ru] KJTLSVCANCCWHF-UHFFFAOYSA-N 0.000 title 1
230000001093 anti-cancer Effects 0.000 title 1
206010028980 Neoplasm Diseases 0.000 abstract 1
201000011510 cancer Diseases 0.000 abstract 1
230000002265 prevention Effects 0.000 abstract 1
YAYGSLOSTXKUBW-UHFFFAOYSA-N ruthenium(2+) Chemical class [Ru+2] YAYGSLOSTXKUBW-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F17/00—Metallocenes
- C07F17/02—Metallocenes of metals of Groups 8, 9 or 10 of the Periodic Table
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT03762788T 2002-07-05 2003-07-04 Rutheniumkomplexe mit antikrebswirkung ATE407937T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB0215526.5A GB0215526D0 (en)	2002-07-05	2002-07-05	Anticancer compounds

Publications (1)

Publication Number	Publication Date
ATE407937T1 true ATE407937T1 (de)	2008-09-15

Family

ID=9939861

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03762788T ATE407937T1 (de)	2002-07-05	2003-07-04	Rutheniumkomplexe mit antikrebswirkung

Country Status (20)

Country	Link
US (1)	US20060058270A1 (de)
EP (1)	EP1558620B1 (de)
JP (1)	JP2005536487A (de)
KR (1)	KR20050053589A (de)
CN (1)	CN100362005C (de)
AT (1)	ATE407937T1 (de)
AU (1)	AU2003251159B2 (de)
BR (1)	BR0312470A (de)
CA (1)	CA2491640A1 (de)
DE (1)	DE60323529D1 (de)
DK (1)	DK1558620T3 (de)
ES (1)	ES2314245T3 (de)
GB (1)	GB0215526D0 (de)
MX (1)	MXPA05000314A (de)
NO (1)	NO20050640L (de)
NZ (1)	NZ538005A (de)
PL (1)	PL373049A1 (de)
PT (1)	PT1558620E (de)
WO (1)	WO2004005304A1 (de)
ZA (1)	ZA200500908B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1224192B1 (de) *	1999-10-27	2005-08-31	The University Court, The University Of Edinburgh	Halbsandwich ruthenium(ii)-verbindungen mit einem stickstoff-haltigen liganden zur krebstherapie
AU2004234127A1 (en)	2003-04-30	2004-11-11	The University Court Of The University Of Edinburgh	Ruthenium (II) complexes for the treatment of tumors
GB0418643D0 (en) *	2004-08-20	2004-09-22	Univ Edinburgh	Ruthenium (II) compounds
GB0604602D0 (en) *	2006-03-07	2006-04-19	Univ Edinburgh	Ruthenium (II) compounds
EP2016085B9 (de)	2006-05-09	2015-12-30	Ecole Polytechnique Fédérale de Lausanne (EPFL)	Übergangsmetallkomplexe zum inhibieren von resistenz bei der behandlung von krebs und metastasen
GB0610062D0 (en) *	2006-05-19	2006-06-28	Univ Edinburgh	Ruthenium (ll) compounds
DE102009053392A1 (de) *	2009-11-14	2011-06-22	Umicore AG & Co. KG, 63457	Verfahren zur Herstellung von Ru(0) Olefin-Komplexen
WO2013038395A1 (en)	2011-09-16	2013-03-21	Universidade De Lisboa	Transition metal complexes for pharmaceutical applications
WO2013136296A2 (en)	2012-03-14	2013-09-19	Universidade De Lisboa	Water-soluble organometallic ruthenium and iron compunds presenting heteroaromatic ligands
CN103360428A (zh) *	2012-04-09	2013-10-23	中国科学院化学研究所	抑制蛋白酪氨酸磷酸酶1b活性的含钌配合物及其制备方法和蛋白酪氨酸磷酸酶1b抑制剂
CN102964385B (zh) *	2012-11-30	2015-02-18	广西师范学院	一种有机金属钌化合物及其制备方法和用途
US9751081B2 (en)	2014-12-01	2017-09-05	Clemson University	Self-regenerating antioxidant catalysts and methods of using the same
CZ310511B6 (cs) *	2023-09-18	2025-09-10	Univerzita Palackého v Olomouci	Koordinační sloučeniny osmia pro použití pro léčbu plicních nádorových onemocnění

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4980473A (en) *	1985-01-18	1990-12-25	The Trustees Of Columbia University In The City Of New York	Chemical probes for left-handed DNA and chiral metal complexes as Z-specific anti-tumor agents
US6184381B1 (en) *	1995-12-06	2001-02-06	Japan Science & Technology Corp.	Process for preparing optically active compounds
EP1224192B1 (de) *	1999-10-27	2005-08-31	The University Court, The University Of Edinburgh	Halbsandwich ruthenium(ii)-verbindungen mit einem stickstoff-haltigen liganden zur krebstherapie
GB0016052D0 (en) *	2000-06-30	2000-08-23	Univ Edinburgh	Ruthenium (II) compounds

2002
- 2002-07-05 GB GBGB0215526.5A patent/GB0215526D0/en not_active Ceased
2003
- 2003-07-04 AU AU2003251159A patent/AU2003251159B2/en not_active Ceased
- 2003-07-04 EP EP03762788A patent/EP1558620B1/de not_active Expired - Lifetime
- 2003-07-04 AT AT03762788T patent/ATE407937T1/de not_active IP Right Cessation
- 2003-07-04 US US10/520,239 patent/US20060058270A1/en not_active Abandoned
- 2003-07-04 DE DE60323529T patent/DE60323529D1/de not_active Expired - Fee Related
- 2003-07-04 JP JP2004518958A patent/JP2005536487A/ja active Pending
- 2003-07-04 DK DK03762788T patent/DK1558620T3/da active
- 2003-07-04 PT PT03762788T patent/PT1558620E/pt unknown
- 2003-07-04 CA CA002491640A patent/CA2491640A1/en not_active Abandoned
- 2003-07-04 ES ES03762788T patent/ES2314245T3/es not_active Expired - Lifetime
- 2003-07-04 PL PL03373049A patent/PL373049A1/xx not_active Application Discontinuation
- 2003-07-04 CN CNB038160005A patent/CN100362005C/zh not_active Expired - Fee Related
- 2003-07-04 BR BR0312470-3A patent/BR0312470A/pt not_active IP Right Cessation
- 2003-07-04 KR KR1020057000143A patent/KR20050053589A/ko not_active Ceased
- 2003-07-04 WO PCT/GB2003/002879 patent/WO2004005304A1/en not_active Ceased
- 2003-07-04 NZ NZ538005A patent/NZ538005A/en unknown
- 2003-07-04 MX MXPA05000314A patent/MXPA05000314A/es active IP Right Grant
2005
- 2005-02-01 ZA ZA200500908A patent/ZA200500908B/xx unknown
- 2005-02-04 NO NO20050640A patent/NO20050640L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
PL373049A1 (en)	2005-08-08
GB0215526D0 (en)	2002-08-14
CA2491640A1 (en)	2004-01-15
ZA200500908B (en)	2006-03-29
AU2003251159A1 (en)	2004-01-23
EP1558620B1 (de)	2008-09-10
BR0312470A (pt)	2005-04-26
NZ538005A (en)	2007-08-31
PT1558620E (pt)	2008-12-03
KR20050053589A (ko)	2005-06-08
US20060058270A1 (en)	2006-03-16
JP2005536487A (ja)	2005-12-02
ES2314245T3 (es)	2009-03-16
AU2003251159B2 (en)	2008-11-06
MXPA05000314A (es)	2005-09-20
CN1665826A (zh)	2005-09-07
CN100362005C (zh)	2008-01-16
EP1558620A1 (de)	2005-08-03
WO2004005304A1 (en)	2004-01-15
NO20050640L (no)	2005-03-22
DK1558620T3 (da)	2009-01-05
DE60323529D1 (de)	2008-10-23

Legal Events

Date

Code

Title

Description

2009-04-15

UEP

Publication of translation of european patent specification

Ref document number: 1558620

Country of ref document: EP

2011-04-15

REN

Ceased due to non-payment of the annual fee

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