|
US7381803B1
(en)
*
|
1992-03-27 |
2008-06-03 |
Pdl Biopharma, Inc. |
Humanized antibodies against CD3
|
|
WO1998047531A2
(en)
*
|
1997-04-21 |
1998-10-29 |
Arch Development Corporation |
Fc receptor non-binding anti-cd3 monoclonal antibodies deliver a partial tcr signal and induce clonal anergy
|
|
US6242195B1
(en)
|
1998-04-02 |
2001-06-05 |
Genentech, Inc. |
Methods for determining binding of an analyte to a receptor
|
|
US6194551B1
(en)
|
1998-04-02 |
2001-02-27 |
Genentech, Inc. |
Polypeptide variants
|
|
US6528624B1
(en)
*
|
1998-04-02 |
2003-03-04 |
Genentech, Inc. |
Polypeptide variants
|
|
CA2323757C
(en)
*
|
1998-04-02 |
2011-08-02 |
Genentech, Inc. |
Antibody variants and fragments thereof
|
|
GB9809951D0
(en)
|
1998-05-08 |
1998-07-08 |
Univ Cambridge Tech |
Binding molecules
|
|
US6737056B1
(en)
*
|
1999-01-15 |
2004-05-18 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
|
US7183387B1
(en)
|
1999-01-15 |
2007-02-27 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
|
HUP0104865A3
(en)
*
|
1999-01-15 |
2004-07-28 |
Genentech Inc |
Polypeptide variants with altered effector function
|
|
DE19905012A1
(de)
*
|
1999-02-08 |
2000-08-10 |
Gsf Forschungszentrum Umwelt |
Arzneimittel enthaltend Anti-CD3- und Anti-Fcgamma-R-Antikörper zur begleitenden Behandlung bei Organtransplantationen
|
|
DE19905048A1
(de)
*
|
1999-02-08 |
2000-08-10 |
Gsf Forschungszentrum Umwelt |
Verwendung depletorisch oder mitogen wirkender Antikörper in der Immuntherapie
|
|
CN1360596A
(zh)
*
|
1999-02-12 |
2002-07-24 |
遗传研究所有限公司 |
与b7分子发生反应的人源化免疫球蛋白及应用该免疫球蛋白的治疗方法
|
|
US6972125B2
(en)
*
|
1999-02-12 |
2005-12-06 |
Genetics Institute, Llc |
Humanized immunoglobulin reactive with B7-2 and methods of treatment therewith
|
|
US6949245B1
(en)
|
1999-06-25 |
2005-09-27 |
Genentech, Inc. |
Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies
|
|
EP1085453A1
(de)
*
|
1999-09-20 |
2001-03-21 |
TELEFONAKTIEBOLAGET LM ERICSSON (publ) |
SIM-Kartenhalter
|
|
SK12942002A3
(sk)
|
2000-02-10 |
2003-05-02 |
Abbott Laboratories |
Protilátky viažuce ľudský interleukín-18, spôsoby ich výroby a použitia
|
|
AU5345901A
(en)
*
|
2000-04-13 |
2001-10-30 |
Univ Rockefeller |
Enhancement of antibody-mediated immune responses
|
|
US20080095774A1
(en)
*
|
2001-02-16 |
2008-04-24 |
Wyeth |
Agents and Methods for Specifically Blocking CD28-Mediated Signaling
|
|
GB2380127A
(en)
*
|
2001-09-26 |
2003-04-02 |
Isis Innovation |
Treatment of chronic joint inflammation
|
|
US7771951B2
(en)
*
|
2001-12-03 |
2010-08-10 |
Amgen Fremont Inc. |
Antibody categorization based on binding characteristics
|
|
WO2003048730A2
(en)
*
|
2001-12-03 |
2003-06-12 |
Abgenix, Inc. |
Identification of high affinity molecules by limited dilution screening
|
|
US20030175760A1
(en)
*
|
2001-12-03 |
2003-09-18 |
Walker Wynn L. |
Discovery of therapeutic products
|
|
US20070148171A1
(en)
*
|
2002-09-27 |
2007-06-28 |
Xencor, Inc. |
Optimized anti-CD30 antibodies
|
|
US7317091B2
(en)
*
|
2002-03-01 |
2008-01-08 |
Xencor, Inc. |
Optimized Fc variants
|
|
US20040132101A1
(en)
|
2002-09-27 |
2004-07-08 |
Xencor |
Optimized Fc variants and methods for their generation
|
|
US8188231B2
(en)
|
2002-09-27 |
2012-05-29 |
Xencor, Inc. |
Optimized FC variants
|
|
US20080254027A1
(en)
*
|
2002-03-01 |
2008-10-16 |
Bernett Matthew J |
Optimized CD5 antibodies and methods of using the same
|
|
US8093357B2
(en)
|
2002-03-01 |
2012-01-10 |
Xencor, Inc. |
Optimized Fc variants and methods for their generation
|
|
US20030216551A1
(en)
*
|
2002-03-08 |
2003-11-20 |
Diabetogen Biosciences Inc. |
Fully human anti-CD3 monoclonal antibodies
|
|
SE0200943D0
(sv)
*
|
2002-03-25 |
2002-03-25 |
Amersham Biosciences Ab |
Mutant protein
|
|
EP2270049A3
(de)
*
|
2002-04-12 |
2011-03-09 |
Medimmune, Inc. |
Rekombinante Anti-Interleukin-9-Antikörper
|
|
CA2487932A1
(en)
*
|
2002-05-30 |
2003-12-11 |
Macrogenics, Inc. |
Cd16a binding proteins and use for the treatment of immune disorders
|
|
US20030235583A1
(en)
*
|
2002-06-14 |
2003-12-25 |
Jeppe Sturis |
Combined use of a modulator of CD3 and a beta cell resting compound
|
|
AU2003253621A1
(en)
*
|
2002-06-14 |
2003-12-31 |
Centocor, Inc. |
Modified "s" antibodies
|
|
WO2003105896A1
(en)
*
|
2002-06-14 |
2003-12-24 |
Novo Nordisk A/S |
Combined use of a modulator of cd3 and a beta cell resting compound
|
|
US20040037826A1
(en)
*
|
2002-06-14 |
2004-02-26 |
Michelsen Birgitte Koch |
Combined use of a modulator of CD3 and a GLP-1 compound
|
|
WO2003105897A1
(en)
*
|
2002-06-14 |
2003-12-24 |
Novo Nordisk A/S |
Combined use of a modulator of cd3 and a glp-1 compound
|
|
AR040778A1
(es)
*
|
2002-08-06 |
2005-04-20 |
Glaxo Group Ltd |
Anticuerpos alterados o fragmentos funcionales que se unen a mag (glicoproteina asociada a mielina).
|
|
US8946387B2
(en)
|
2002-08-14 |
2015-02-03 |
Macrogenics, Inc. |
FcγRIIB specific antibodies and methods of use thereof
|
|
US8187593B2
(en)
|
2002-08-14 |
2012-05-29 |
Macrogenics, Inc. |
FcγRIIB specific antibodies and methods of use thereof
|
|
US8530627B2
(en)
|
2002-08-14 |
2013-09-10 |
Macrogenics, Inc. |
FcγRIIB specific antibodies and methods of use thereof
|
|
US8968730B2
(en)
|
2002-08-14 |
2015-03-03 |
Macrogenics Inc. |
FcγRIIB specific antibodies and methods of use thereof
|
|
US20060235208A1
(en)
*
|
2002-09-27 |
2006-10-19 |
Xencor, Inc. |
Fc variants with optimized properties
|
|
US7217797B2
(en)
*
|
2002-10-15 |
2007-05-15 |
Pdl Biopharma, Inc. |
Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
|
|
US7365168B2
(en)
*
|
2002-10-15 |
2008-04-29 |
Pdl Biopharma, Inc. |
Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
|
|
US7361740B2
(en)
*
|
2002-10-15 |
2008-04-22 |
Pdl Biopharma, Inc. |
Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
|
|
US20040253237A1
(en)
*
|
2002-12-05 |
2004-12-16 |
Ian Walters |
Methods of treatment of ulcerative colitis with anti-CD3 antibodies
|
|
ATE471946T1
(de)
*
|
2002-12-17 |
2010-07-15 |
Merck Patent Gmbh |
Humanisierter antikörper (h14.18) des maus antikörpers 14.18, der gd2 bindet und seine fusion mit il-2
|
|
US7960512B2
(en)
|
2003-01-09 |
2011-06-14 |
Macrogenics, Inc. |
Identification and engineering of antibodies with variant Fc regions and methods of using same
|
|
US7355008B2
(en)
|
2003-01-09 |
2008-04-08 |
Macrogenics, Inc. |
Identification and engineering of antibodies with variant Fc regions and methods of using same
|
|
US20080014594A1
(en)
*
|
2003-01-31 |
2008-01-17 |
Kevin Hestir |
Lung-Expressed Polypeptides
|
|
US20090010920A1
(en)
|
2003-03-03 |
2009-01-08 |
Xencor, Inc. |
Fc Variants Having Decreased Affinity for FcyRIIb
|
|
US20070275460A1
(en)
*
|
2003-03-03 |
2007-11-29 |
Xencor.Inc. |
Fc Variants With Optimized Fc Receptor Binding Properties
|
|
US8084582B2
(en)
|
2003-03-03 |
2011-12-27 |
Xencor, Inc. |
Optimized anti-CD20 monoclonal antibodies having Fc variants
|
|
US8388955B2
(en)
|
2003-03-03 |
2013-03-05 |
Xencor, Inc. |
Fc variants
|
|
CN1798767B
(zh)
*
|
2003-04-10 |
2011-02-16 |
晶面生物技术公司 |
通过诱变来改变抗体对FcRn的结合亲和力或血清半衰期
|
|
KR101224235B1
(ko)
*
|
2003-04-11 |
2013-01-25 |
메디뮨 엘엘씨 |
재조합 il9 항체 및 그의 용도
|
|
CU23403A1
(es)
*
|
2003-04-23 |
2009-08-04 |
Centro Inmunologia Molecular |
Anticuerpos recombinantes y fragmentos que reconocen el gangliósido n-glicolil gm3 y su uso para diagnóstico y tratamiento de tumores
|
|
US9051373B2
(en)
|
2003-05-02 |
2015-06-09 |
Xencor, Inc. |
Optimized Fc variants
|
|
US7700097B2
(en)
*
|
2003-06-27 |
2010-04-20 |
Biogen Idec Ma Inc. |
Purification and preferential synthesis of binding molecules
|
|
US8101720B2
(en)
|
2004-10-21 |
2012-01-24 |
Xencor, Inc. |
Immunoglobulin insertions, deletions and substitutions
|
|
US9714282B2
(en)
|
2003-09-26 |
2017-07-25 |
Xencor, Inc. |
Optimized Fc variants and methods for their generation
|
|
EP1673395A1
(de)
*
|
2003-10-15 |
2006-06-28 |
PDL BioPharma, Inc. |
Veränderungen der serum-halbwertszeiten von fc-fusionsprotein durch mutagenese der position 250, 314 und/oder 428 der schweren kette der konstanten region von ig
|
|
US7883703B2
(en)
*
|
2003-11-14 |
2011-02-08 |
The Brigham And Women's Hospital, Inc. |
Methods of modulating immunity
|
|
EP1697520A2
(de)
*
|
2003-12-22 |
2006-09-06 |
Xencor, Inc. |
Fc-polypeptide mit neuen fc-ligandenbindungsstellen
|
|
AU2005213449A1
(en)
*
|
2004-02-04 |
2005-08-25 |
The La Jolla Institute For Allergy And Immunology |
Anti-CD3 and antigen-specific immunotherapy to treat autoimmunity
|
|
US7276585B2
(en)
*
|
2004-03-24 |
2007-10-02 |
Xencor, Inc. |
Immunoglobulin variants outside the Fc region
|
|
US7794713B2
(en)
|
2004-04-07 |
2010-09-14 |
Lpath, Inc. |
Compositions and methods for the treatment and prevention of hyperproliferative diseases
|
|
US8921528B2
(en)
|
2004-06-01 |
2014-12-30 |
Domantis Limited |
Bispecific fusion antibodies with enhanced serum half-life
|
|
NZ551180A
(en)
|
2004-06-01 |
2009-10-30 |
Genentech Inc |
Antibody drug conjugates and methods
|
|
SG188175A1
(en)
*
|
2004-06-03 |
2013-03-28 |
Novimmune Sa |
Anti-cd3 antibodies and methods of use thereof
|
|
US20150010550A1
(en)
|
2004-07-15 |
2015-01-08 |
Xencor, Inc. |
OPTIMIZED Fc VARIANTS
|
|
BRPI0514068B8
(pt)
|
2004-08-04 |
2021-05-25 |
Applied Molecular Evolution Inc |
anticorpo anti-cd20, e, composição farmacêutica
|
|
US20060074225A1
(en)
*
|
2004-09-14 |
2006-04-06 |
Xencor, Inc. |
Monomeric immunoglobulin Fc domains
|
|
AU2005335714B2
(en)
|
2004-11-10 |
2012-07-26 |
Macrogenics, Inc. |
Engineering Fc antibody regions to confer effector function
|
|
US8546543B2
(en)
|
2004-11-12 |
2013-10-01 |
Xencor, Inc. |
Fc variants that extend antibody half-life
|
|
US8367805B2
(en)
|
2004-11-12 |
2013-02-05 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
|
US9200079B2
(en)
|
2004-11-12 |
2015-12-01 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
|
US8802820B2
(en)
|
2004-11-12 |
2014-08-12 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
|
JP5185624B2
(ja)
|
2004-12-02 |
2013-04-17 |
ドマンティス リミテッド |
血清アルブミンおよびglp−1またはpyyを標的とする二重特異性抗体
|
|
RU2481356C2
(ru)
|
2004-12-28 |
2013-05-10 |
Иннейт Фарма |
Моноклональные антитела против nkg2a
|
|
CA2595169A1
(en)
*
|
2005-01-12 |
2006-07-20 |
Xencor, Inc. |
Antibodies and fc fusion proteins with altered immunogenicity
|
|
WO2006093794A1
(en)
*
|
2005-02-28 |
2006-09-08 |
Centocor, Inc. |
Heterodimeric protein binding compositions
|
|
JP5838021B2
(ja)
|
2005-04-15 |
2015-12-24 |
マクロジェニクス,インコーポレーテッド |
共有結合型ダイアボディとその使用
|
|
US11254748B2
(en)
|
2005-04-15 |
2022-02-22 |
Macrogenics, Inc. |
Covalent diabodies and uses thereof
|
|
US9284375B2
(en)
|
2005-04-15 |
2016-03-15 |
Macrogenics, Inc. |
Covalent diabodies and uses thereof
|
|
US9963510B2
(en)
|
2005-04-15 |
2018-05-08 |
Macrogenics, Inc. |
Covalent diabodies and uses thereof
|
|
DK2573114T3
(en)
|
2005-08-10 |
2016-07-04 |
Macrogenics Inc |
The identification and production of antibodies with variant Fc regions, and methods of using same
|
|
AU2006291005A1
(en)
*
|
2005-09-12 |
2007-03-22 |
Novimmune S.A. |
Anti-CD3 antibody formulations
|
|
DK1931709T3
(en)
*
|
2005-10-03 |
2017-03-13 |
Xencor Inc |
FC VARIETIES WITH OPTIMIZED FC RECEPTOR BINDING PROPERTIES
|
|
JP4860703B2
(ja)
*
|
2005-10-06 |
2012-01-25 |
ゼンコー・インコーポレイテッド |
最適化された抗cd30抗体
|
|
AR059922A1
(es)
|
2006-04-01 |
2008-05-07 |
Galaxy Biotech Llc |
Anticuerpos monoclonales humanizados para el factor de crecimiento de hepatocitos
|
|
CA2660592C
(en)
|
2006-05-26 |
2016-07-12 |
Macrogenics, Inc. |
Humanized fc.gamma.riib-specific antibodies and methods of use thereof
|
|
PT2032606E
(pt)
|
2006-05-30 |
2014-02-05 |
Genentech Inc |
Anticorpos e imunoconjugados e respetivas utilizações
|
|
US7862812B2
(en)
|
2006-05-31 |
2011-01-04 |
Lpath, Inc. |
Methods for decreasing immune response and treating immune conditions
|
|
US20090258001A1
(en)
*
|
2006-06-06 |
2009-10-15 |
Paul Ponath |
Administration of anti-CD3 antibodies in the treatment of autoimmune diseases
|
|
JP2009544761A
(ja)
|
2006-06-14 |
2009-12-17 |
マクロジェニクス,インコーポレーテッド |
低毒性免疫抑制モノクローナル抗体を用いて自己免疫疾患を治療する方法
|
|
EP2032159B1
(de)
|
2006-06-26 |
2015-01-07 |
MacroGenics, Inc. |
Kombination aus fcgammariib-antikörpern und cd20-spezifischen antikörpern sowie verwendungsverfahren dafür
|
|
EP2029173B1
(de)
|
2006-06-26 |
2016-07-20 |
MacroGenics, Inc. |
Fc-riib-spezifische antikörper und verfahren zu ihrer anwendung
|
|
RS53263B
(sr)
|
2006-08-14 |
2014-08-29 |
Xencor Inc. |
Optimizovana antitela usmerena na cd19
|
|
EP2064240A2
(de)
|
2006-09-18 |
2009-06-03 |
Xencor, Inc. |
Optimierte auf hm1.24 abzielende antikörper
|
|
WO2008070344A2
(en)
*
|
2006-10-27 |
2008-06-12 |
Lpath, Inc. |
Compositions and methods for binding sphingosine-1-phosphate
|
|
US8614103B2
(en)
*
|
2006-10-27 |
2013-12-24 |
Lpath, Inc. |
Compositions and methods for treating sphingosine-1-phosphate (S1P) related ocular diseases and conditions
|
|
PT2845866T
(pt)
|
2006-10-27 |
2017-08-09 |
Genentech Inc |
Anticorpos e imunoconjugados e utilizações dos mesmos
|
|
US8652466B2
(en)
|
2006-12-08 |
2014-02-18 |
Macrogenics, Inc. |
Methods for the treatment of disease using immunoglobulins having Fc regions with altered affinities for FcγRactivating and FcγRinhibiting
|
|
US8465741B2
(en)
*
|
2006-12-20 |
2013-06-18 |
Mmrglobal, Inc. |
Antibodies and methods for making and using them
|
|
US9163091B2
(en)
*
|
2007-05-30 |
2015-10-20 |
Lpath, Inc. |
Compositions and methods for binding lysophosphatidic acid
|
|
DK2164992T3
(en)
*
|
2007-05-30 |
2016-08-15 |
Lpath Inc |
COMPOSITIONS AND METHODS FOR BONDING OF LYTHOPHOSPHATIC ACID
|
|
US7580304B2
(en)
*
|
2007-06-15 |
2009-08-25 |
United Memories, Inc. |
Multiple bus charge sharing
|
|
PE20090499A1
(es)
|
2007-08-09 |
2009-05-18 |
Boehringer Ingelheim Int |
Anticuerpos anti-cd37
|
|
US8361465B2
(en)
*
|
2007-10-26 |
2013-01-29 |
Lpath, Inc. |
Use of anti-sphingosine-1-phosphate antibodies in combination with chemotherapeutic agents
|
|
WO2015164330A1
(en)
|
2014-04-21 |
2015-10-29 |
Millennium Pharmaceuticals, Inc. |
Anti-psyk antibody molecules and use of same for syk-targeted therapy
|
|
WO2009117030A2
(en)
|
2007-12-19 |
2009-09-24 |
Macrogenics, Inc. |
Improved compositions for the prevention and treatment of smallpox
|
|
KR101616758B1
(ko)
|
2007-12-26 |
2016-04-29 |
젠코어 인코포레이티드 |
FcRn에 대한 변경된 결합성을 갖는 Fc 변이체
|
|
US12492253B1
(en)
|
2008-02-25 |
2025-12-09 |
Xencor, Inc. |
Anti-human C5 antibodies
|
|
CN106349390B
(zh)
|
2008-04-02 |
2019-12-10 |
宏观基因有限公司 |
Bcr-复合体-特异性抗体和其使用方法
|
|
SG189730A1
(en)
|
2008-04-02 |
2013-05-31 |
Macrogenics Inc |
Her2/neu-specific antibodies and methods of using same
|
|
KR101590495B1
(ko)
|
2008-05-29 |
2016-02-01 |
갤럭시 바이오테크, 엘엘씨 |
염기성 섬유모세포 성장 인자에 대한 모노클로날 항체
|
|
NZ592611A
(en)
*
|
2008-10-10 |
2013-01-25 |
Emergent Product Dev Seattle |
A single chain fusion protein that binds to tcr complex and does not induce or induces a minimally detectable cytokine release
|
|
US8871202B2
(en)
|
2008-10-24 |
2014-10-28 |
Lpath, Inc. |
Prevention and treatment of pain using antibodies to sphingosine-1-phosphate
|
|
DK3290052T3
(da)
|
2008-11-07 |
2020-02-03 |
Galaxy Biotech Llc |
Monoklonale antistoffer mod fibroblastvækstfaktorreceptor 2
|
|
EP2374001A4
(de)
*
|
2008-12-05 |
2013-03-13 |
Lpath Inc |
Antikörperdesign unter verwendung von anti-lipid-antikörper-kristallstrukturen
|
|
US8401799B2
(en)
*
|
2008-12-05 |
2013-03-19 |
Lpath, Inc. |
Antibody design using anti-lipid antibody crystal structures
|
|
EP2400981A4
(de)
*
|
2009-02-26 |
2013-02-27 |
Lpath Inc |
Desgin für humanisierten thrombozytenaktivierungsfaktor-antikörper mittels anti-lipid-antikörper-templates
|
|
RU2595379C2
(ru)
|
2009-04-16 |
2016-08-27 |
АббВай Биотерапеутикс Инк. |
АНТИТЕЛА ПРОТИВ TNF-α И ИХ ПРИМЕНЕНИЯ
|
|
EP2419446A4
(de)
*
|
2009-04-17 |
2013-01-23 |
Lpath Inc |
Humanisierte antikörperzusammensetzungen und verfahren zur bindung von lysophosphatidsäure
|
|
RU2567639C2
(ru)
|
2009-06-17 |
2015-11-10 |
АббВай Биотерапеутикс Инк., |
Антитела против vegf и их применения
|
|
US9493578B2
(en)
|
2009-09-02 |
2016-11-15 |
Xencor, Inc. |
Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
|
|
AU2010292172A1
(en)
|
2009-09-09 |
2012-05-03 |
Centrose, Llc |
Extracellular targeted drug conjugates
|
|
MX2012004029A
(es)
|
2009-10-07 |
2012-05-08 |
Macrogenics Inc |
Polipeptidos que contienen la region fc que exhiben funcion efectora mejorada debido a alteraciones del grado de fucosilacion, y metodos para su uso.
|
|
MY173390A
(en)
|
2009-10-23 |
2020-01-22 |
Takeda Pharmaceuticals Co |
Anti-gcc antibody molecules and related compositions and methods
|
|
US8658175B2
(en)
|
2009-10-28 |
2014-02-25 |
Abbvie Biotherapeutics Inc. |
Anti-EGFR antibodies and their uses
|
|
CN102711810B
(zh)
*
|
2009-11-30 |
2015-04-22 |
詹森生物科技公司 |
效应子功能已消除的抗体Fc区突变体
|
|
US10053513B2
(en)
|
2009-11-30 |
2018-08-21 |
Janssen Biotech, Inc. |
Antibody Fc mutants with ablated effector functions
|
|
EP2513148B1
(de)
|
2009-12-16 |
2016-08-31 |
AbbVie Biotherapeutics Inc. |
Anti-her2-antikörper und ihre verwendung
|
|
WO2011075185A1
(en)
|
2009-12-18 |
2011-06-23 |
Oligasis |
Targeted drug phosphorylcholine polymer conjugates
|
|
US8362210B2
(en)
|
2010-01-19 |
2013-01-29 |
Xencor, Inc. |
Antibody variants with enhanced complement activity
|
|
US20110212088A1
(en)
*
|
2010-02-26 |
2011-09-01 |
Sabbadini Roger A |
Anti-paf antibodies
|
|
PH12012501751A1
(en)
|
2010-03-04 |
2012-11-12 |
Macrogenics Inc |
Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof
|
|
DK2542256T3
(da)
|
2010-03-04 |
2019-08-26 |
Macrogenics Inc |
Antistoffer reagerende med b7-h3, immunologisk aktive fragmenter deraf og anvendelser deraf
|
|
WO2011113019A2
(en)
|
2010-03-12 |
2011-09-15 |
Abbott Biotherapeutics Corp. |
Ctla4 proteins and their uses
|
|
NZ701208A
(en)
|
2010-06-03 |
2016-05-27 |
Genentech Inc |
Immuno-pet imaging of antibodies and immunoconjugates and uses thereof
|
|
ES2667100T3
(es)
|
2010-08-02 |
2018-05-09 |
Macrogenics, Inc. |
Diacuerpos covalentes y sus usos
|
|
UA112062C2
(uk)
|
2010-10-04 |
2016-07-25 |
Бьорінгер Інгельхайм Інтернаціональ Гмбх |
Cd33-зв'язувальний агент
|
|
PT3156420T
(pt)
|
2010-12-06 |
2019-05-27 |
Seattle Genetics Inc |
Anticorpos humanizados a liv-1 e seu uso para tratar o cancro
|
|
LT2691417T
(lt)
|
2011-03-29 |
2018-10-25 |
Roche Glycart Ag |
Antikūno fc variantai
|
|
EP2699256B1
(de)
|
2011-04-21 |
2017-09-27 |
The Regents of the University of Colorado, a body corporate |
Zusammensetzungen und verfahren zur behandlung von neuromyelitis optica
|
|
BR112013027224A8
(pt)
|
2011-04-22 |
2018-08-14 |
Emergent Product Dev Seattle |
Proteínas de ligação de antígeno de membrana específico de próstata e composições e métodos relacionados
|
|
US9376495B2
(en)
|
2011-05-21 |
2016-06-28 |
Macrogenics, Inc. |
Deimmunized serum-binding domains and their use in extending serum half-life
|
|
WO2012162067A2
(en)
*
|
2011-05-21 |
2012-11-29 |
Macrogenics, Inc. |
Cd3-binding molecules capable of binding to human and non-human cd3
|
|
WO2013022091A1
(ja)
|
2011-08-11 |
2013-02-14 |
小野薬品工業株式会社 |
Pd-1アゴニストからなる自己免疫疾患治療剤
|
|
US12466897B2
(en)
|
2011-10-10 |
2025-11-11 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
|
EP2771031B1
(de)
|
2011-10-28 |
2018-04-18 |
Prothena Biosciences Limited |
Alpha-synuklein erkennende humanisierte antikörper
|
|
EP2807188B1
(de)
|
2012-01-27 |
2019-09-11 |
Prothena Biosciences Limited |
Alpha-synuclein erkennende humanisierte antikörper
|
|
IN2014MN02293A
(de)
|
2012-04-20 |
2015-08-07 |
Emergent Product Dev Seattle |
|
|
US9156915B2
(en)
|
2012-04-26 |
2015-10-13 |
Thomas Jefferson University |
Anti-GCC antibody molecules
|
|
US20130309223A1
(en)
|
2012-05-18 |
2013-11-21 |
Seattle Genetics, Inc. |
CD33 Antibodies And Use Of Same To Treat Cancer
|
|
SI3495387T1
(sl)
|
2012-07-13 |
2021-12-31 |
Roche Glycart Ag |
Bispecifična protitelesa proti VEGF/proti ANG-2 in njihova uporaba pri zdravljenju bolezni očesnih žil
|
|
RU2648141C2
(ru)
|
2012-09-19 |
2018-03-22 |
Эббви Биотерапьютикс Инк. |
Способы идентификации антител с пониженной иммуногенностью
|
|
UA118441C2
(uk)
|
2012-10-08 |
2019-01-25 |
Протена Біосаєнсиз Лімітед |
Антитіло, що розпізнає альфа-синуклеїн
|
|
US20140154255A1
(en)
|
2012-11-30 |
2014-06-05 |
Abbvie Biotherapeutics Inc. |
Anti-vegf antibodies and their uses
|
|
US9487587B2
(en)
|
2013-03-05 |
2016-11-08 |
Macrogenics, Inc. |
Bispecific molecules that are immunoreactive with immune effector cells of a companion animal that express an activating receptor and cells that express B7-H3 and uses thereof
|
|
WO2014165271A2
(en)
|
2013-03-13 |
2014-10-09 |
Neotope Biosciences Limited |
Tau immunotherapy
|
|
CA2906566C
(en)
|
2013-03-14 |
2024-09-10 |
Macrogenics, Inc. |
Immunoreactive bispecific molecules at immune effector cells expressing an activation receptor
|
|
AU2014233478A1
(en)
|
2013-03-15 |
2015-09-24 |
Abbvie Biotechnology Ltd. |
Anti-CD25 antibodies and their uses
|
|
US10858417B2
(en)
|
2013-03-15 |
2020-12-08 |
Xencor, Inc. |
Heterodimeric proteins
|
|
EP2970489A2
(de)
|
2013-03-15 |
2016-01-20 |
AbbVie Biotechnology Ltd |
Anti-cd25-antikörper und deren verwendungen
|
|
US10513555B2
(en)
|
2013-07-04 |
2019-12-24 |
Prothena Biosciences Limited |
Antibody formulations and methods
|
|
US9850302B2
(en)
|
2013-07-12 |
2017-12-26 |
Prothena Biosciences Limited |
Antibodies that recognize IAPP
|
|
WO2015004633A1
(en)
|
2013-07-12 |
2015-01-15 |
Neotope Biosciences Limited |
Antibodies that recognize islet-amyloid polypeptide (iapp)
|
|
JP6693872B2
(ja)
|
2013-07-25 |
2020-05-13 |
シトムクス セラピューティクス,インコーポレイティド |
多重特異性抗体、多重特異性活性化可能抗体、及びそれらの使用方法
|
|
US11384149B2
(en)
|
2013-08-09 |
2022-07-12 |
Macrogenics, Inc. |
Bi-specific monovalent Fc diabodies that are capable of binding CD32B and CD79b and uses thereof
|
|
UA116479C2
(uk)
|
2013-08-09 |
2018-03-26 |
Макродженікс, Інк. |
БІСПЕЦИФІЧНЕ МОНОВАЛЕНТНЕ Fc-ДІАТІЛО, ЯКЕ ОДНОЧАСНО ЗВ'ЯЗУЄ CD32B I CD79b, ТА ЙОГО ЗАСТОСУВАННЯ
|
|
EP2840091A1
(de)
|
2013-08-23 |
2015-02-25 |
MacroGenics, Inc. |
Bispezifische Diabodies, die gpA33 und CD3 binden können und Anwendungen dieser
|
|
EP2839842A1
(de)
|
2013-08-23 |
2015-02-25 |
MacroGenics, Inc. |
Bispezifische monovalente Diabodies mit Fähigkeit zur Bindung von CD123 und CD3 und Verwendungen davon
|
|
ES2819217T3
(es)
|
2013-09-08 |
2021-04-15 |
Kodiak Sciences Inc |
Conjugados de polímeros iónicos dipolares y factor VIII
|
|
US11191832B2
(en)
|
2013-11-19 |
2021-12-07 |
Prothena Biosciences Limited |
Monitoring immunotherapy of Lewy body disease from constipation symptoms
|
|
KR20210125114A
(ko)
|
2013-12-09 |
2021-10-15 |
알라코스 인크. |
항-Siglec-8 항체 및 그의 사용 방법
|
|
JP2017506640A
(ja)
|
2014-02-14 |
2017-03-09 |
セントローズ, エルエルシー |
細胞外標的化薬物共役体
|
|
JP6825909B2
(ja)
|
2014-02-28 |
2021-02-03 |
アラコス インコーポレイテッド |
シグレック−8関連疾患を処置するための方法および組成物
|
|
TW201623331A
(zh)
|
2014-03-12 |
2016-07-01 |
普羅帝納生物科學公司 |
抗黑色素瘤細胞黏著分子(mcam)抗體類及使用彼等之相關方法
|
|
EP3116906A1
(de)
|
2014-03-12 |
2017-01-18 |
Prothena Biosciences Limited |
Für lg1-3 spezifische anti-laminin4-antikörper
|
|
WO2015136472A1
(en)
|
2014-03-12 |
2015-09-17 |
Prothena Biosciences Limited |
Anti-laminin4 antibodies specific for lg4-5
|
|
PT3116911T
(pt)
|
2014-03-12 |
2019-09-04 |
Prothena Biosciences Ltd |
Anticorpos anti-mcam e métodos de utilização associados
|
|
US20170002077A1
(en)
|
2014-03-13 |
2017-01-05 |
Prothena Biosciences Limited |
Combination treatment for multiple sclerosis
|
|
US10562973B2
(en)
|
2014-04-08 |
2020-02-18 |
Prothena Bioscience Limited |
Blood-brain barrier shuttles containing antibodies recognizing alpha-synuclein
|
|
WO2015200905A2
(en)
|
2014-06-28 |
2015-12-30 |
Oligasis, Llc |
Dual pdgf/vegf antagonists
|
|
CA2955947A1
(en)
|
2014-07-25 |
2016-01-28 |
Cytomx Therapeutics, Inc. |
Anti-cd3 antibodies, activatable anti-cd3 antibodies, multispecific anti-cd3 antibodies, multispecific activatable anti-cd3 antibodies, and methods of using the same
|
|
CA2959629C
(en)
|
2014-09-03 |
2023-10-31 |
Boehringer Ingelheim International Gmbh |
Compound targeting il-23a and tnf-alpha and uses thereof
|
|
US20160075772A1
(en)
|
2014-09-12 |
2016-03-17 |
Regeneron Pharmaceuticals, Inc. |
Treatment of Fibrodysplasia Ossificans Progressiva
|
|
WO2016054101A1
(en)
|
2014-09-29 |
2016-04-07 |
Duke University |
Bispecific molecules comprising an hiv-1 envelope targeting arm
|
|
EP3207128B1
(de)
|
2014-10-17 |
2022-07-27 |
Kodiak Sciences Inc. |
Zwitterionische butyrylcholinesterasepolymerkonjugate
|
|
CA2966005C
(en)
|
2014-10-31 |
2021-04-27 |
Abbvie Biotherapeutics Inc. |
Anti-cs1 antibodies and antibody drug conjugates
|
|
JP6805142B2
(ja)
|
2014-11-21 |
2020-12-23 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
Cd73に対する抗体およびその使用
|
|
ES2826566T3
(es)
|
2014-11-21 |
2021-05-18 |
Bristol Myers Squibb Co |
Anticuerpos que comprenden regiones constantes pesadas modificadas
|
|
US10259887B2
(en)
|
2014-11-26 |
2019-04-16 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and tumor antigens
|
|
HK1245171A1
(zh)
|
2014-11-26 |
2018-08-24 |
Xencor, Inc. |
结合cd3和cd38的异二聚体抗体
|
|
JP6696982B2
(ja)
|
2014-11-26 |
2020-05-20 |
ゼンコー・インコーポレイテッドXencor、 Inc. |
Cd3および腫瘍抗原に結合するヘテロ二量体抗体
|
|
AR103268A1
(es)
|
2014-12-23 |
2017-04-26 |
Bristol Myers Squibb Co |
Anticuerpos contra tigit
|
|
TWI769570B
(zh)
|
2015-01-28 |
2022-07-01 |
愛爾蘭商普羅佘納生物科技有限公司 |
抗甲狀腺素運送蛋白抗體
|
|
TWI718121B
(zh)
|
2015-01-28 |
2021-02-11 |
愛爾蘭商普羅佘納生物科技有限公司 |
抗甲狀腺素運送蛋白抗體
|
|
TWI786505B
(zh)
|
2015-01-28 |
2022-12-11 |
愛爾蘭商普羅佘納生物科技有限公司 |
抗甲狀腺素運送蛋白抗體
|
|
KR20170128256A
(ko)
|
2015-03-18 |
2017-11-22 |
시애틀 지네틱스, 인크. |
Cd48 항체 및 이의 접합체
|
|
DK3277725T3
(da)
|
2015-03-30 |
2021-01-11 |
Regeneron Pharma |
Konstante tungkædeområder med reduceret binding til FC-gammareceptorer
|
|
AU2016249404B2
(en)
|
2015-04-17 |
2021-01-21 |
Igm Biosciences, Inc. |
Multi-valent human immunodeficiency virus antigen binding molecules and uses thereof
|
|
KR20170140318A
(ko)
|
2015-04-29 |
2017-12-20 |
리제너론 파마슈티칼스 인코포레이티드 |
진행성 골화성 섬유이형성증의 치료
|
|
AU2016271111B2
(en)
|
2015-05-29 |
2022-04-28 |
Bristol-Myers Squibb Company |
Antibodies against OX40 and uses thereof
|
|
TW201709932A
(zh)
|
2015-06-12 |
2017-03-16 |
西雅圖遺傳學公司 |
Cd123抗體及其共軛物
|
|
HK1254432A1
(zh)
|
2015-06-17 |
2019-07-19 |
Allakos Inc. |
用於治疗纤维性疾病的方法和组合物
|
|
KR20180021705A
(ko)
|
2015-06-30 |
2018-03-05 |
시애틀 지네틱스, 인크. |
항-ntb-a 항체 및 관련 조성물 및 방법
|
|
GB201513033D0
(en)
*
|
2015-07-23 |
2015-09-09 |
Ucb Biopharma Sprl |
Proteins
|
|
WO2017046776A2
(en)
|
2015-09-16 |
2017-03-23 |
Prothena Biosciences Limited |
Use of anti-mcam antibodies for treatment or prophylaxis of giant cell arteritis, polymyalgia rheumatica or takayasu's arteritis
|
|
WO2017046774A2
(en)
|
2015-09-16 |
2017-03-23 |
Prothena Biosciences Limited |
Use of anti-mcam antibodies for treatment or prophylaxis of giant cell arteritis, polymyalgia rheumatica or takayasu's arteritis
|
|
HK1251480A1
(zh)
|
2015-09-21 |
2019-02-01 |
Aptevo Research And Development Llc |
Cd3结合多肽
|
|
US10604577B2
(en)
|
2015-10-22 |
2020-03-31 |
Allakos Inc. |
Methods and compositions for treating systemic mastocytosis
|
|
MX391162B
(es)
|
2015-10-30 |
2025-03-21 |
Galaxy Biotech Llc |
Anticuerpos altamente potentes que se unen a receptor de muerte 4 y receptor de muerte 5
|
|
WO2017079369A2
(en)
*
|
2015-11-03 |
2017-05-11 |
Glaxosmithkline Llc |
Novel antibodies
|
|
EP3371311B1
(de)
|
2015-11-06 |
2021-07-21 |
Orionis Biosciences BV |
Bifunktionale chimäre proteine und verwendungen davon
|
|
IL290457B2
(en)
|
2015-12-30 |
2025-02-01 |
Kodiak Sciences Inc |
Antibodies and their conjugates
|
|
CN109071632B
(zh)
|
2016-02-05 |
2022-12-30 |
奥里尼斯生物科学私人有限公司 |
靶向性治疗剂及其用途
|
|
MA44254A
(fr)
|
2016-02-17 |
2018-12-26 |
Seattle Genetics Inc |
Anticorps bcma et leur utilisation pour traiter le cancer et les troubles immunologiques
|
|
WO2017149513A1
(en)
|
2016-03-03 |
2017-09-08 |
Prothena Biosciences Limited |
Anti-mcam antibodies and associated methods of use
|
|
AU2017228470A1
(en)
|
2016-03-04 |
2018-08-30 |
Bristol-Myers Squibb Company |
Combination therapy with anti-CD73 antibodies
|
|
MX2018010485A
(es)
|
2016-03-04 |
2019-01-10 |
Jn Biosciences Llc |
Anticuerpos para inmunoreceptor de celulas t con dominios de ig e itim (tigit).
|
|
WO2017153955A1
(en)
|
2016-03-09 |
2017-09-14 |
Prothena Biosciences Limited |
Use of anti-mcam antibodies for treatment or prophylaxis of granulomatous lung diseases
|
|
WO2017153953A1
(en)
|
2016-03-09 |
2017-09-14 |
Prothena Biosciences Limited |
Use of anti-mcam antibodies for treatment or prophylaxis of granulomatous lung diseases
|
|
CN109069633A
(zh)
|
2016-04-15 |
2018-12-21 |
宏观基因有限公司 |
新颖的b7-h3-结合分子、其抗体药物缀合物及其使用方法
|
|
US11016085B2
(en)
|
2016-04-25 |
2021-05-25 |
The Johns Hopkins University |
ZNT8 assays for drug development and pharmaceutical compositions
|
|
EP3452507B1
(de)
|
2016-05-02 |
2022-10-19 |
Prothena Biosciences Limited |
Tau-immuntherapie
|
|
MX2018013384A
(es)
|
2016-05-02 |
2019-02-28 |
Prothena Biosciences Ltd |
Anticuerpos que reconocen tau.
|
|
US10906964B2
(en)
|
2016-05-02 |
2021-02-02 |
Prothena Biosciences Limited |
Antibodies recognizing tau
|
|
US10968279B2
(en)
|
2016-05-09 |
2021-04-06 |
Bristol-Myers Squibb Company |
TL1A antibodies and uses thereof
|
|
US10875921B2
(en)
|
2016-05-27 |
2020-12-29 |
Abbvie Biotherapeutics Inc. |
Anti-4-1BB antibodies and their uses
|
|
KR20190014525A
(ko)
|
2016-05-27 |
2019-02-12 |
애브비 바이오테라퓨틱스 인크. |
면역 조절 단백질과 종양 항원을 결합하는 이중특이적 결합 단백질
|
|
SMT202100721T1
(it)
|
2016-05-27 |
2022-01-10 |
Abbvie Biotherapeutics Inc |
Anticorpi anti-cd40 e loro usi
|
|
WO2017208210A1
(en)
|
2016-06-03 |
2017-12-07 |
Prothena Biosciences Limited |
Anti-mcam antibodies and associated methods of use
|
|
KR102379464B1
(ko)
|
2016-06-20 |
2022-03-29 |
키맵 리미티드 |
항-pd-l1 항체
|
|
RU2019102008A
(ru)
|
2016-06-28 |
2020-07-28 |
Ксенкор, Инк. |
Гетеродимерные антитела, которые связывают рецептор соматостатина 2-го типа
|
|
EP3478714A2
(de)
|
2016-07-02 |
2019-05-08 |
Prothena Biosciences Limited |
Anti-transthyretin-antikörper
|
|
JP7016470B2
(ja)
|
2016-07-02 |
2022-02-07 |
プロセナ バイオサイエンシーズ リミテッド |
抗トランスサイレチン抗体
|
|
JP7017013B2
(ja)
|
2016-07-02 |
2022-02-08 |
プロセナ バイオサイエンシーズ リミテッド |
抗トランスサイレチン抗体
|
|
MX2019002946A
(es)
|
2016-09-14 |
2019-09-26 |
Abbvie Biotherapeutics Inc |
Anticuerpos anti-pd-1 y sus usos.
|
|
EP3515491A4
(de)
*
|
2016-09-21 |
2020-09-16 |
Aptevo Research and Development LLC |
Cd123-bindende proteine sowie zugehörige zusammensetzungen und verfahren
|
|
UY37523A
(es)
|
2016-12-15 |
2018-07-31 |
Abbvie Biotherapeutics Inc |
Anticuerpos anti-ox40 y sus usos
|
|
EP3576765B1
(de)
|
2017-02-06 |
2025-07-16 |
Orionis Biosciences, Inc. |
Zielgerichtetes manipuliertes interferon und verwendungen davon
|
|
CA3059938A1
(en)
|
2017-04-14 |
2018-10-18 |
Kodiak Sciences Inc. |
Complement factor d antagonist antibodies and conjugates thereof
|
|
SG11201910066QA
(en)
|
2017-05-02 |
2019-11-28 |
Prothena Biosciences Ltd |
Antibodies recognizing tau
|
|
BR112019022912A2
(pt)
|
2017-05-05 |
2020-05-26 |
Allakos Inc. |
Métodos e composições para tratar doenças oculares alérgicas
|
|
MX2019013132A
(es)
|
2017-05-25 |
2020-01-27 |
Bristol Myers Squibb Co |
Anticuerpos que comprenden regiones constantes pesadas modificadas.
|
|
CN111316099A
(zh)
|
2017-07-12 |
2020-06-19 |
约翰霍普金斯大学 |
用于1型糖尿病诊断的基于脂蛋白体的znt8自身抗原
|
|
US11680110B2
(en)
|
2017-07-31 |
2023-06-20 |
Hoffmann-La Roche Inc. |
Three-dimensional structure-based humanization method
|
|
CA3076313A1
(en)
|
2017-09-28 |
2019-04-04 |
Prothena Biosciences Limited |
Dosing regimes for treatment of synucleinopathies
|
|
KR102581734B1
(ko)
|
2017-10-06 |
2023-09-22 |
네오토프 뉴로사이언스 리미티드 |
트랜스타이레틴의 검출 방법
|
|
EP3694883A1
(de)
|
2017-10-12 |
2020-08-19 |
Keio University |
Monoklonaler anti-aqp3-antikörper, der spezifisch an die extrazelluläre domäne von aquaporin 3 (aqp3) bindet, und verwendung davon
|
|
AU2018366199A1
(en)
|
2017-11-08 |
2020-05-28 |
Xencor, Inc. |
Bispecific and monospecific antibodies using novel anti-PD-1 sequences
|
|
MA51223A
(fr)
|
2017-11-29 |
2020-10-07 |
Prothena Biosciences Ltd |
Formulation lyophilisée d'un anticorps monoclonal contre la transthyrétine
|
|
CN111699004A
(zh)
|
2018-02-06 |
2020-09-22 |
豪夫迈·罗氏有限公司 |
眼科疾病的治疗
|
|
TWI849895B
(zh)
|
2018-02-09 |
2024-07-21 |
日商小野藥品工業股份有限公司 |
雙特異性抗體
|
|
CA3092588A1
(en)
|
2018-03-02 |
2019-09-06 |
Kodiak Sciences Inc. |
Il-6 antibodies and fusion constructs and conjugates thereof
|
|
CN112469477A
(zh)
|
2018-04-04 |
2021-03-09 |
Xencor股份有限公司 |
与成纤维细胞活化蛋白结合的异源二聚体抗体
|
|
WO2019195561A2
(en)
|
2018-04-06 |
2019-10-10 |
BioLegend, Inc. |
Anti-tetraspanin 33 agents and compositions and methods for making and using the same
|
|
WO2019222296A1
(en)
|
2018-05-14 |
2019-11-21 |
Werewolf Therapeutics, Inc. |
Activatable interleukin 12 polypeptides and methods of use thereof
|
|
MX2020012251A
(es)
|
2018-05-14 |
2021-04-28 |
Werewolf Therapeutics Inc |
Polipeptidos de interleucina-2 activables y metodos de uso de los mismos.
|
|
US20210130430A1
(en)
|
2018-05-14 |
2021-05-06 |
Werewolf Therapeutics, Inc. |
Activatable cytokine polypeptides and methods of use thereof
|
|
TWI920652B
(zh)
|
2018-06-07 |
2026-04-01 |
美商思進公司 |
喜樹鹼結合物
|
|
WO2020037174A1
(en)
|
2018-08-16 |
2020-02-20 |
The Johns Hopkins University |
Antibodies to human znt8
|
|
EP3841123A2
(de)
|
2018-08-23 |
2021-06-30 |
Seagen Inc. |
Anti-tigit-antikörper
|
|
WO2020068557A1
(en)
|
2018-09-25 |
2020-04-02 |
BioLegend, Inc. |
Anti-tlr9 agents and compositions and methods for making and using the same
|
|
CN113286812B
(zh)
|
2018-09-27 |
2025-05-30 |
西里欧发展公司 |
掩蔽型细胞因子多肽
|
|
US12590169B2
(en)
|
2018-10-11 |
2026-03-31 |
Inhibrx Biosciences, Inc. |
5T4 single domain antibodies and therapeutic compositions thereof
|
|
AU2019356573B2
(en)
|
2018-10-11 |
2025-12-18 |
Inhibrx Biosciences, Inc. |
PD-1 single domain antibodies and therapeutic compositions thereof
|
|
JP7611820B2
(ja)
|
2018-10-11 |
2025-01-10 |
インヒブルクス バイオサイエンシズ インコーポレイテッド |
Dll3シングルドメイン抗体およびその治療用組成物
|
|
CN113166261A
(zh)
|
2018-10-11 |
2021-07-23 |
印希比股份有限公司 |
B7h3单域抗体及其治疗性组合物
|
|
CN119033684A
(zh)
|
2018-10-29 |
2024-11-29 |
豪夫迈·罗氏有限公司 |
抗体制剂
|
|
SG11202104549TA
(en)
|
2018-11-08 |
2021-05-28 |
Prothena Biosciences Ltd |
Antibodies recognizing tau
|
|
UA128431C2
(uk)
|
2018-11-26 |
2024-07-10 |
Форті Севен, Інк. |
ГУМАНІЗОВАНЕ АНТИТІЛО ДО c-Kit
|
|
JP2022513653A
(ja)
|
2018-11-28 |
2022-02-09 |
ブリストル-マイヤーズ スクイブ カンパニー |
修飾された重鎖定常領域を含む抗体
|
|
KR20210094609A
(ko)
|
2018-11-28 |
2021-07-29 |
포티 세븐, 인코포레이티드 |
절제 레짐에 대해 저항성인 유전적으로 변형된 hspc
|
|
BR112021012631A2
(pt)
|
2018-12-26 |
2021-12-14 |
Xilio Dev Inc |
Anticorpos anti-ctla4 e métodos de uso dos mesmos
|
|
JP7754715B2
(ja)
|
2019-02-05 |
2025-10-15 |
シージェン インコーポレイテッド |
抗cd228抗体及び抗体薬物コンジュゲート
|
|
TWI859197B
(zh)
|
2019-03-03 |
2024-10-21 |
愛爾蘭商普羅帝納生物科學公司 |
識別tau之抗體
|
|
WO2020213084A1
(en)
|
2019-04-17 |
2020-10-22 |
Keio University |
Anti aqp3 monoclonal antibody specifically binding to extracellular domain of aquaporin 3 (aqp3) and use thereof
|
|
BR112021022666A2
(pt)
|
2019-05-14 |
2022-03-29 |
Werewolf Therapeutics Inc |
Frações de separação e seus métodos e uso
|
|
WO2020250940A1
(ja)
|
2019-06-11 |
2020-12-17 |
小野薬品工業株式会社 |
免疫抑制剤
|
|
CN114245807B
(zh)
|
2019-06-25 |
2025-05-02 |
吉利德科学公司 |
Flt3l-fc融合蛋白和使用方法
|
|
US12366570B2
(en)
|
2019-10-01 |
2025-07-22 |
The Johns Hopkins University |
Cell-based ZNT8 assay
|
|
BR112022005114A2
(pt)
|
2019-10-04 |
2022-06-21 |
Seagen Inc |
Anticorpo, composição farmacêutica, métodos para tratar câncer e para produzir um conjugado anticorpo-fármaco e um anticorpo, ácido nucleico, vetor, célula hospedeira, e, conjugado anticorpo-fármaco
|
|
CA3157509A1
(en)
|
2019-10-10 |
2021-04-15 |
Kodiak Sciences Inc. |
Methods of treating an eye disorder
|
|
BR112022009110A2
(pt)
|
2019-11-14 |
2022-07-26 |
Werewolf Therapeutics Inc |
Polipeptídeos de citocina ativáveis e métodos de uso destes
|
|
CN118562007A
(zh)
*
|
2019-12-19 |
2024-08-30 |
苏州方德门达新药开发有限公司 |
工程改造的t细胞、其制备及应用
|
|
CN115052663B
(zh)
|
2020-01-08 |
2026-06-09 |
辛瑟斯治疗股份有限公司 |
Alk5抑制剂缀合物及其用途
|
|
IL294611B1
(en)
|
2020-01-08 |
2026-05-01 |
Regeneron Pharma |
Treatment of fibrodysplasia ossificans progressive
|
|
CN115427447B
(zh)
|
2020-01-17 |
2025-02-18 |
百进生物科技公司 |
抗tlr7药剂和组合物以及制备和使用其的方法
|
|
JP7859981B2
(ja)
|
2020-03-06 |
2026-05-15 |
ジーオー セラピューティクス,インコーポレイテッド |
抗グリコcd44抗体およびその使用
|
|
WO2021195362A1
(en)
|
2020-03-26 |
2021-09-30 |
Seagen Inc. |
Methods of treating multiple myeloma
|
|
WO2021231976A1
(en)
|
2020-05-14 |
2021-11-18 |
Xencor, Inc. |
Heterodimeric antibodies that bind prostate specific membrane antigen (psma) and cd3
|
|
US20230192867A1
(en)
|
2020-05-15 |
2023-06-22 |
Bristol-Myers Squibb Company |
Antibodies to garp
|
|
TW202210514A
(zh)
|
2020-06-02 |
2022-03-16 |
美商阿克思生物科學有限公司 |
針對tigit的抗體
|
|
AU2021297540A1
(en)
|
2020-06-24 |
2023-02-02 |
Prothena Biosciences Limited |
Antibodies recognizing sortilin
|
|
AU2021310926A1
(en)
|
2020-07-23 |
2023-03-23 |
Othair Prothena Limited |
Anti-abeta antibodies
|
|
AU2021320739A1
(en)
|
2020-08-04 |
2023-02-23 |
Seagen Inc. |
Anti-CD228 antibodies and antibody-drug conjugates
|
|
JP7518286B2
(ja)
|
2020-08-25 |
2024-07-17 |
ギリアード サイエンシーズ, インコーポレイテッド |
Hivを標的とする多重特異性抗原結合分子及び使用方法
|
|
TWI815194B
(zh)
|
2020-10-22 |
2023-09-11 |
美商基利科學股份有限公司 |
介白素2-Fc融合蛋白及使用方法
|
|
WO2022093640A1
(en)
|
2020-10-30 |
2022-05-05 |
BioLegend, Inc. |
Anti-nkg2c agents and compositions and methods for making and using the same
|
|
WO2022093641A1
(en)
|
2020-10-30 |
2022-05-05 |
BioLegend, Inc. |
Anti-nkg2a agents and compositions and methods for making and using the same
|
|
TW202233248A
(zh)
|
2020-11-08 |
2022-09-01 |
美商西健公司 |
組合療法
|
|
EP4251187A4
(de)
|
2020-11-25 |
2025-09-10 |
Xilio Dev Inc |
Tumorspezifische spaltbare linker
|
|
TW202237638A
(zh)
|
2020-12-09 |
2022-10-01 |
日商武田藥品工業股份有限公司 |
烏苷酸環化酶c(gcc)抗原結合劑之組成物及其使用方法
|
|
TW202237639A
(zh)
|
2020-12-09 |
2022-10-01 |
日商武田藥品工業股份有限公司 |
鳥苷酸環化酶c(gcc)抗原結合劑之組成物及其使用方法
|
|
WO2022172085A2
(en)
|
2021-02-15 |
2022-08-18 |
Takeda Pharmaceutical Company Limited |
Cell therapy compositions and methods for modulating tgf-b signaling
|
|
WO2022187272A1
(en)
|
2021-03-01 |
2022-09-09 |
Xilio Development, Inc. |
Combination of masked ctla4 and pd1/pdl1 antibodies for treating cancer
|
|
TW202317612A
(zh)
|
2021-03-01 |
2023-05-01 |
美商艾希利歐發展股份有限公司 |
用於治療癌症的ctla4及pd1/pdl1抗體之組合
|
|
EP4301782A1
(de)
|
2021-03-05 |
2024-01-10 |
Go Therapeutics, Inc. |
Anti-glyco-cd44-antikörper und deren verwendungen
|
|
EP4305067A1
(de)
|
2021-03-09 |
2024-01-17 |
Xencor, Inc. |
Cd3 und cldn6 bindende heterodimere antikörper
|
|
US11859012B2
(en)
|
2021-03-10 |
2024-01-02 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and GPC3
|
|
JP2024514816A
(ja)
|
2021-04-09 |
2024-04-03 |
シージェン インコーポレイテッド |
抗tigit抗体を用いるがんの治療方法
|
|
WO2022245671A1
(en)
|
2021-05-18 |
2022-11-24 |
Gilead Sciences, Inc. |
Methods of using flt3l-fc fusion proteins
|
|
JP2024531915A
(ja)
|
2021-08-05 |
2024-09-03 |
ジーオー セラピューティクス,インコーポレイテッド |
抗グリコmuc抗体およびその使用
|
|
AU2022328714A1
(en)
|
2021-08-20 |
2024-02-29 |
The Johns Hopkins University |
Cell-surface antibody to a specific biomarker of pancreatic beta-cells
|
|
WO2023034569A1
(en)
|
2021-09-03 |
2023-03-09 |
Go Therapeutics, Inc. |
Anti-glyco-cmet antibodies and their uses
|
|
JP2024534910A
(ja)
|
2021-09-03 |
2024-09-26 |
ジーオー セラピューティクス,インコーポレイテッド |
抗グリコlamp1抗体およびその使用
|
|
TW202327650A
(zh)
|
2021-09-23 |
2023-07-16 |
美商思進公司 |
治療多發性骨髓瘤之方法
|
|
WO2023174925A1
(en)
|
2022-03-14 |
2023-09-21 |
Novimmune Sa |
Bispecific gpc3xcd28 and gpc3xcd3 antibodies and their combination for targeted killing of gpc3 positive malignant cells
|
|
CN119156228A
(zh)
|
2022-05-02 |
2024-12-17 |
艾库斯生物科学有限公司 |
抗tigit抗体及其用途
|
|
EP4558523A1
(de)
|
2022-07-19 |
2025-05-28 |
Biolegend, Inc. |
Anti-cd157-antikörper, antigenbindende fragmente davon sowie zusammensetzungen und verfahren zur herstellung und verwendung davon
|
|
US20260042848A1
(en)
|
2022-08-18 |
2026-02-12 |
BioLegend, Inc. |
Anti-axl antibodies, antigen-binding fragments thereof and methods for making and using the same
|
|
JP2025537099A
(ja)
|
2022-11-03 |
2025-11-14 |
シージェン インコーポレイテッド |
抗αVβ6抗体および抗体-薬物コンジュゲートならびにがんの治療におけるそれらの使用
|
|
WO2024108053A1
(en)
|
2022-11-17 |
2024-05-23 |
Sanofi |
Ceacam5 antibody-drug conjugates and methods of use thereof
|
|
TW202434629A
(zh)
|
2023-01-26 |
2024-09-01 |
愛爾蘭商歐薩爾普羅席納有限公司 |
以抗類澱粉β (ABETA)抗體治療神經病症之方法
|
|
TW202448960A
(zh)
|
2023-02-07 |
2024-12-16 |
美商Go治療公司 |
包括抗醣MUC4抗體及MIC蛋白α1-α2結構域之抗體融合蛋白及其用途
|
|
WO2024191807A1
(en)
|
2023-03-10 |
2024-09-19 |
Seagen Inc. |
Methods of treating cancer with anti-tigit antibodies
|
|
CN121152803A
(zh)
|
2023-05-25 |
2025-12-16 |
百进公司 |
Ceacam6结合抗体和其抗原结合片段
|
|
CN121285743A
(zh)
|
2023-06-02 |
2026-01-06 |
艾库斯生物科学有限公司 |
用于预测癌症治疗功效的生物标志物
|
|
WO2024258967A1
(en)
|
2023-06-13 |
2024-12-19 |
Synthis Therapeutics, Inc. |
Anti-cd5 antibodies and their uses
|
|
WO2025059486A1
(en)
|
2023-09-15 |
2025-03-20 |
Prothena Biosciences Limited |
Anti-tdp-43 antibodies and uses thereof
|
|
CN122070299A
(zh)
|
2023-09-15 |
2026-05-19 |
普罗塞纳生物科学有限公司 |
细胞穿透剂及其用途
|
|
WO2025059487A2
(en)
|
2023-09-15 |
2025-03-20 |
Othair Prothena Limited |
Cell penetrating agents and uses thereof
|
|
WO2025072313A1
(en)
|
2023-09-27 |
2025-04-03 |
BioLegend, Inc. |
Anti-gpc4 antibodies
|
|
WO2025151752A1
(en)
|
2024-01-10 |
2025-07-17 |
Xilio Development, Inc. |
Masked il-2 cytokines and methods of use thereof
|
|
TW202545567A
(zh)
|
2024-01-30 |
2025-12-01 |
美商思進公司 |
抗pd-l1抗體和抗體-藥物共軛體及彼等在治療癌症的用途
|
|
WO2025193146A1
(en)
|
2024-03-13 |
2025-09-18 |
Berg Thoren Fredrik |
Trail receptor binding molecules
|
|
WO2025199352A2
(en)
|
2024-03-20 |
2025-09-25 |
Juno Therapeutics, Inc. |
Antibodies specific for solute carrier family 34 member 2 (slc34a2)
|
|
US20250295801A1
(en)
|
2024-03-21 |
2025-09-25 |
Seagen Inc. |
Cd25 antibodies, antibody drug conjugates, and uses thereof
|
|
WO2025240670A2
(en)
|
2024-05-15 |
2025-11-20 |
Abalytics Oncology, Inc. |
Anti-pd-1 antibodies and related binding molecules and methods and uses thereof
|
|
WO2025245176A1
(en)
|
2024-05-22 |
2025-11-27 |
Bristol-Myers Squibb Company |
Multispecific antibody constructs
|
|
WO2026006495A1
(en)
|
2024-06-25 |
2026-01-02 |
Alloy Therapeutics, Inc. |
Anti-wt1/hla-a2 antibody and uses thereof
|
|
WO2026006492A2
(en)
|
2024-06-25 |
2026-01-02 |
Ypsilon Therapeutics, Inc. |
Anti-prame/hla-a2 antibodies and uses thereof
|
|
WO2026055669A2
(en)
|
2024-09-09 |
2026-03-12 |
Xencor, Inc. |
Anti-tl1a x anti-il23 antibodies
|
|
WO2026088163A1
(en)
|
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