ATE409030T1 - Sphingolipiden zur verbesserung der darmflorazusammensetzung - Google Patents

Sphingolipiden zur verbesserung der darmflorazusammensetzung

Info

Publication number: ATE409030T1
Authority: AT; Austria
Prior art keywords: sphingolipids; intestinal; improve; composition; food
Prior art date: 2003-01-20

Application number

AT04703547T

Other languages

English (en)

Inventor

Willem Nieuwenhuizen

Original Assignee

Tno

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-01-20

Filing date

2004-01-20

Publication date

2008-10-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32768715&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE409030(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2004-01-20 Application filed by Tno filed Critical Tno

2008-10-15 Application granted granted Critical

2008-10-15 Publication of ATE409030T1 publication Critical patent/ATE409030T1/de

Links

150000003408 sphingolipids Chemical class 0.000 title abstract 4
230000000968 intestinal effect Effects 0.000 title abstract 3
238000000034 method Methods 0.000 abstract 4
WWUZIQQURGPMPG-UHFFFAOYSA-N (-)-D-erythro-Sphingosine Natural products CCCCCCCCCCCCCC=CC(O)C(N)CO WWUZIQQURGPMPG-UHFFFAOYSA-N 0.000 abstract 1
OKTWQKXBJUBAKS-WQADZSDSSA-N 2-[[(e,2r,3s)-2-amino-3-hydroxyoctadec-4-enoxy]-hydroxyphosphoryl]oxyethyl-trimethylazanium;chloride Chemical compound [Cl-].CCCCCCCCCCCCC\C=C\[C@H](O)[C@H](N)COP(O)(=O)OCC[N+](C)(C)C OKTWQKXBJUBAKS-WQADZSDSSA-N 0.000 abstract 1
AERBNCYCJBRYDG-UHFFFAOYSA-N D-ribo-phytosphingosine Natural products CCCCCCCCCCCCCCC(O)C(O)C(N)CO AERBNCYCJBRYDG-UHFFFAOYSA-N 0.000 abstract 1
OTKJDMGTUTTYMP-UHFFFAOYSA-N dihydrosphingosine Natural products CCCCCCCCCCCCCCCC(O)C(N)CO OTKJDMGTUTTYMP-UHFFFAOYSA-N 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
AERBNCYCJBRYDG-KSZLIROESA-N phytosphingosine Chemical compound CCCCCCCCCCCCCC[C@@H](O)[C@@H](O)[C@@H](N)CO AERBNCYCJBRYDG-KSZLIROESA-N 0.000 abstract 1
229940033329 phytosphingosine Drugs 0.000 abstract 1
239000002243 precursor Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
OTKJDMGTUTTYMP-ZWKOTPCHSA-N sphinganine Chemical compound CCCCCCCCCCCCCCC[C@@H](O)[C@@H](N)CO OTKJDMGTUTTYMP-ZWKOTPCHSA-N 0.000 abstract 1
WWUZIQQURGPMPG-KRWOKUGFSA-N sphingosine Chemical compound CCCCCCCCCCCCC\C=C\[C@@H](O)[C@@H](N)CO WWUZIQQURGPMPG-KRWOKUGFSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/688—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols both hydroxy compounds having nitrogen atoms, e.g. sphingomyelins
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Nutrition Science (AREA)
General Chemical & Material Sciences (AREA)
Polymers & Plastics (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Food Science & Technology (AREA)
Oil, Petroleum & Natural Gas (AREA)
Mycology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Bioinformatics & Cheminformatics (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Coloring Foods And Improving Nutritive Qualities (AREA)
Confectionery (AREA)
Saccharide Compounds (AREA)

AT04703547T 2003-01-20 2004-01-20 Sphingolipiden zur verbesserung der darmflorazusammensetzung ATE409030T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
NL1022443A NL1022443C2 (nl)	2003-01-20	2003-01-20	Sphingolipiden voor verbetering van de samenstelling van de darmflora.

Publications (1)

Publication Number	Publication Date
ATE409030T1 true ATE409030T1 (de)	2008-10-15

Family

ID=32768715

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT04703547T ATE409030T1 (de)	2003-01-20	2004-01-20	Sphingolipiden zur verbesserung der darmflorazusammensetzung

Country Status (7)

Country	Link
US (1)	US8703172B2 (de)
EP (1)	EP1585509B1 (de)
JP (1)	JP2006516278A (de)
AT (1)	ATE409030T1 (de)
DE (1)	DE602004016727D1 (de)
NL (1)	NL1022443C2 (de)
WO (1)	WO2004064819A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ITRM20010688A1 (it)	2001-11-21	2003-05-21	Univ Roma	Composti immunoregolatori.
WO2004064820A2 (en)	2003-01-20	2004-08-05	Nederlandse Organisatie Voor Toegepast- Natuurwetenschappelijk Onderzoek Tno	Use of sphingolipids for reducing plasma cholesterol and triacylglycerol levels
NL1022443C2 (nl)	2003-01-20	2004-07-22	Tno	Sphingolipiden voor verbetering van de samenstelling van de darmflora.
US20050196461A1 (en) *	2004-01-14	2005-09-08	Udell Ronald G.	Ceramide formulations suitable for oral administration
JP2005281257A (ja) *	2004-03-30	2005-10-13	Snow Brand Milk Prod Co Ltd	美肌剤
ATE539741T1 (de)	2004-11-30	2012-01-15	Tno	Sphingolipide bei der behandlung und prävention von hepatischer steatose
US8025552B2 (en) *	2004-12-30	2011-09-27	The United States Of America As Represented By The Secretary Of Agriculture	Artificial diets for honey bees
GB0513431D0 (en) *	2005-06-30	2005-08-10	Kherion Technology Ltd	Prophylactic compositions and uses
US20090162482A1 (en) *	2007-12-21	2009-06-25	S.A.F.E. Research & Development, Llc	Nutritional Compositions for Bees
EP2234505B1 (de) *	2007-12-21	2013-01-30	N.V. Nutricia	Verwendung von sphingomyelin und unverdaulichen kohlenhydraten für die verbesserung der darmflora
JP6675752B2 (ja) *	2016-02-23	2020-04-01	国立大学法人佐賀大学	腸内Ｂｌａｕｔｉａｃｏｃｃｏｉｄｅｓ増殖刺激剤

Family Cites Families (59)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3622666A (en) *	1968-03-04	1971-11-23	Stanley Drug Products Inc	Methods for treating bacterial infections with phrenosin
FR2492259A1 (fr)	1980-10-21	1982-04-23	Idinvex Sa	Formulation d'heparine
JPS61152632A (ja)	1984-12-26	1986-07-11	Dai Ichi Seiyaku Co Ltd	抗動脈硬化剤
JPS6344842A (ja)	1986-08-12	1988-02-25	Kao Corp	油中水中油型乳化油脂組成物
IT1235162B (it)	1988-12-02	1992-06-22	Fidia Farmaceutici	Derivati di lisosfingolipidi
US5190876A (en)	1988-12-27	1993-03-02	Emory University	Method of modifying cellular differentiation and function and compositions therefor
EP0543922A4 (en)	1990-08-13	1993-07-28	Duke University	Methods for inducing cell differentiation using ceramides
US5543390A (en) *	1990-11-01	1996-08-06	State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University	Covalent microparticle-drug conjugates for biological targeting
US5232837A (en)	1991-08-05	1993-08-03	Emory University	Method of altering sphingolipid metabolism and detecting fumonisin ingestion and contamination
US5374616A (en)	1991-10-18	1994-12-20	Georgetown University	Compositions containing sphingosylphosphorylcholine and the use thereof as a cellular growth factor
JPH05320048A (ja)	1992-05-19	1993-12-03	Shiseido Co Ltd	抗酸化剤
US6190894B1 (en)	1993-03-19	2001-02-20	The Regents Of The University Of California	Method and compositions for disrupting the epithelial barrier function
US5478860A (en)	1993-06-04	1995-12-26	Inex Pharmaceuticals Corp.	Stable microemulsions for hydrophobic compound delivery
US5830853A (en)	1994-06-23	1998-11-03	Astra Aktiebolag	Systemic administration of a therapeutic preparation
US6773719B2 (en)	1994-03-04	2004-08-10	Esperion Luv Development, Inc.	Liposomal compositions, and methods of using liposomal compositions to treat dislipidemias
US20020182250A1 (en)	1995-09-06	2002-12-05	Goro Hori	Lipid metabolism improving agent
US5714478A (en)	1995-09-29	1998-02-03	Spiegel; Sarah	Sphingosylphosphorylcholine as a wound-healing agent
DE19602108A1 (de) *	1996-01-22	1997-07-24	Beiersdorf Ag	Gegen Bakterien, Parasiten, Protozoen, Mycota und Viren wirksame Substanzen
WO1997030174A1 (en)	1996-02-20	1997-08-21	Sloan-Kettering Institute For Cancer Research	Combinations of pkc inhibitors and therapeutic agents for treating cancers
DE69724782T3 (de)	1996-03-28	2015-12-24	Dsm Ip Assets B.V.	Verfahren zur Herstellung von granulärer mikrobieller Biomasse und Gewinnung wertvoller Komponenten aus mikrobieller Biomasse
CN1222293C (zh)	1997-04-10	2005-10-12	麒麟麦酒株式会社	含有α－糖基神经酰胺的NKT细胞活化剂
US6800661B1 (en)	1997-04-15	2004-10-05	Board Of Trustees Of The University Of Illinois	Spisulosine compounds
KR100541271B1 (ko)	1997-05-02	2006-04-21	코스모페름 베.파우	국소적 사용을 위한 항균조성물
US5989803A (en)	1997-09-05	1999-11-23	The Trustees Of Columbia University In The City Of New York	Method for treating a subject suffering from a condition associated with an extracellular zinc sphingomyelinase
KR100561890B1 (ko) *	1997-09-11	2006-03-16	다카라 바이오 가부시키가이샤	스핑고신류 유도체 및 의약 조성물
US6610835B1 (en) *	1998-02-12	2003-08-26	Emory University	Sphingolipid derivatives and their methods of use
JP3581010B2 (ja)	1998-03-18	2004-10-27	雪印乳業株式会社	脂質の消化吸収機能改善剤
CA2329124A1 (en)	1998-05-26	1999-12-02	Office Of The Dean Of Research And Graduate Education	Sphingosine kinase, cloning, expression and methods of use
WO2000050574A1 (en)	1999-02-24	2000-08-31	Johns Hopkins University	Compositions and methods for modulating serum cholesterol
JP3544493B2 (ja)	1999-06-10	2004-07-21	雪印乳業株式会社	乳幼児用栄養組成物
KR100341793B1 (ko)	1999-07-02	2002-06-24	권 영 근	스핑고신 1-포스페이트를 유효성분으로 포함하는 혈관신생 촉진제
WO2001003739A1 (fr)	1999-07-12	2001-01-18	Ono Pharmaceutical Co., Ltd.	Inhibiteurs de fibrose contenant comme ingredient actif l'agoniste du recepteur de sphingosine-1-phosphate ou la sphingosine-1-phosphate
JP2001213858A (ja)	1999-11-24	2001-08-07	Sagami Chem Res Center	スフィンゴシン誘導体
JP2001158735A (ja)	1999-11-30	2001-06-12	Snow Brand Milk Prod Co Ltd	歯周病の予防及び改善剤
JP2001158736A (ja)	1999-11-30	2001-06-12	Snow Brand Milk Prod Co Ltd	骨関節疾患の予防及び改善剤
WO2001060807A1 (en)	2000-02-18	2001-08-23	Merck & Co. Inc.	Aryloxyacetic acids for diabetes and lipid disorders
EP1268414A1 (de)	2000-03-28	2003-01-02	The Liposome Company, Inc.	Ceramid-derivate und verwendungsmethode
JP2002068998A (ja)	2000-08-29	2002-03-08	Meiji Milk Prod Co Ltd	経腸栄養および静脈栄養に伴う脂肪肝発生予防組成物
AU2001212597A1 (en)	2000-10-27	2002-05-06	N.V. Marc Boone	Method for obtaining products enriched in phospho- and sphingolipids
US6949247B2 (en)	2000-12-28	2005-09-27	Unilever Home & Personal Care Usa Division Of Conopco, Inc.	Stable skin care compositions containing a retinoid and a retinoid booster system
FR2820037B1 (fr) *	2001-01-29	2005-12-09	Dermaconcept Jmc	Composition dermatologique a usage veterinaire comprenant une base sphingoide
JP2002226394A (ja)	2001-02-01	2002-08-14	Meiji Milk Prod Co Ltd	脂質代謝改善組成物
ATE554779T1 (de)	2001-06-18	2012-05-15	Neptune Technologies & Bioressources Inc	Krill zur prävention und/oder behandlung von herz-kreislauf-erkrankungen
US8030348B2 (en)	2001-07-27	2011-10-04	Neptune Technologies & Bioressources, Inc.	Natural marine source phospholipids comprising polyunsaturated fatty acids and their applications
EP1291340B1 (de)	2001-09-05	2006-03-15	Charmzone Co., Ltd	Phytosphingosinderivate mit Antitumorwirkung
US20030109044A1 (en)	2001-10-16	2003-06-12	Millennium Pharmaceuticals, Inc.	Methods of using 279, a human G protein-coupled protein receptor
JP4035759B2 (ja)	2001-11-06	2008-01-23	独立行政法人産業技術総合研究所	アミノアルコールリン酸化合物、製造方法、及びその利用方法
JP2003155231A (ja) *	2001-11-20	2003-05-27	Kikkoman Corp	医薬及び抗アレルギー剤
JP2003252765A (ja) *	2002-02-28	2003-09-10	Snow Brand Milk Prod Co Ltd	腸管運動機能不全性疾患の治療剤
DE10217555A1 (de)	2002-04-19	2004-02-19	Degussa Bioactives Deutschland Gmbh	Physiologisch verträgliche, Phospholipid-haltige, stabile und harte Matrix
JP2006507223A (ja)	2002-05-17	2006-03-02	エスペリオンセラピューティクス，インコーポレイテッド	脂質代謝異常疾患の治療方法
AU2002349521A1 (en)	2002-08-14	2004-03-03	Tae-Yoon Kim	A composition comprising phytospingosine derivatives for apoptosis induction
WO2004064820A2 (en)	2003-01-20	2004-08-05	Nederlandse Organisatie Voor Toegepast- Natuurwetenschappelijk Onderzoek Tno	Use of sphingolipids for reducing plasma cholesterol and triacylglycerol levels
NL1022443C2 (nl)	2003-01-20	2004-07-22	Tno	Sphingolipiden voor verbetering van de samenstelling van de darmflora.
GB0301395D0 (en)	2003-01-21	2003-02-19	Univ Aston	Inflammatory disorder treatment
US9717754B2 (en)	2003-02-27	2017-08-01	Enzo Therapeutics, Inc.	Glucocerebroside treatment of disease
US20040171522A1 (en)	2003-02-27	2004-09-02	Yaron Ilan	Regulation of immune responses by manipulation of intermediary metabolite levels
EP1617808A4 (de)	2003-04-25	2011-11-02	Penn State Res Found	Verfahren und system für die systemische abgabe von wachstumshemmenden von lipiden stammenden bioaktiven verbindungen
US8282773B2 (en)	2007-12-14	2012-10-09	Andritz Inc.	Method and system to enhance fiber development by addition of treatment agent during mechanical pulping

2003
- 2003-01-20 NL NL1022443A patent/NL1022443C2/nl not_active IP Right Cessation
2004
- 2004-01-20 DE DE602004016727T patent/DE602004016727D1/de not_active Expired - Lifetime
- 2004-01-20 WO PCT/NL2004/000046 patent/WO2004064819A1/en not_active Ceased
- 2004-01-20 US US10/542,838 patent/US8703172B2/en not_active Expired - Fee Related
- 2004-01-20 JP JP2006500733A patent/JP2006516278A/ja active Pending
- 2004-01-20 AT AT04703547T patent/ATE409030T1/de not_active IP Right Cessation
- 2004-01-20 EP EP04703547A patent/EP1585509B1/de not_active Revoked

Also Published As

Publication number	Publication date
JP2006516278A (ja)	2006-06-29
DE602004016727D1 (de)	2008-11-06
US8703172B2 (en)	2014-04-22
EP1585509B1 (de)	2008-09-24
WO2004064819A1 (en)	2004-08-05
NL1022443C2 (nl)	2004-07-22
EP1585509A1 (de)	2005-10-19
US20060134182A1 (en)	2006-06-22

Legal Events

Date	Code	Title	Description
2009-03-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
EA201170053A1 (ru)	2011-08-30	Способ получения и сушки твердого разагилина в форме основания
ATE409030T1 (de)	2008-10-15	Sphingolipiden zur verbesserung der darmflorazusammensetzung
TW200505837A (en)	2005-02-16	Novel compounds
ATE485262T1 (de)	2010-11-15	Verfahren zur herstellung von di- und polyaminen der diphenylmethanreihe
TW200519075A (en)	2005-06-16	Novel compounds
DE60235810D1 (de)	2010-05-12	Verfahren zur herstellung von l-aminosäuren durch enterobacteriaceae-stämme mit verstärkter expression des fba-gens
ATE427106T1 (de)	2009-04-15	Die verwendung von sphingolipiden zur senkung der cholesterin- und triglyzeridspiegel im plasma.
DE602004030239D1 (de)	2011-01-05	Verfahren und zwischenprodukte zur herstellung von (1r,2s,5s)-6,6-dimethyl-3-azabicycloä3,1,0 ühexan-2-carboxylaten oder salzen davon
TW200510277A (en)	2005-03-16	Crystalline form of β2-adrenergic receptor agonist
ATE444950T1 (de)	2009-10-15	Verfahren zur herstellung von 1-amino-3,5- dimethyladamantan-hydrochlorid
IN2012DN04085A (de)	2015-08-07
TW200621690A (en)	2006-07-01	Novel compounds
EP1920774A4 (de)	2008-09-24	Zusammensetzung mit fucoidan oder fucoidan-hydrolysat und immunpotenzierendes material
WO2003048784A3 (en)	2003-12-18	Internal standards for sphingolipids for use in mass spectrometry
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DE602007008731D1 (de)	2010-10-07	Verfahren zur herstellung einer l-aminosäure unter verwendung eines bakteriums der familie enterobacteriaceae mit abgeschwächter expression des rspab-operons
JP2006516278A5 (de)	2007-03-01
ATE531784T1 (de)	2011-11-15	Verfahren zur herstellung von sapucainha-öl oder butter, kosmetische oder pharmazeutische zusammensetzung und verwendung des sapucainha-öls oder der sapucainha-butter,
DE60308066D1 (de)	2006-10-12	Verfahren zur herstellung von hyperpolarisiertem 129xe
TW200640898A (en)	2006-12-01	Anethole dithiolethione and other dithiolethiones for the treatment of conditions associated with dysfunction of monoamine neurotransmission
DE602005024809D1 (de)	2010-12-30	Verfahren zur herstellung von gabapentin
NO20033707L (no)	2003-10-20	Fremgangsmåte for fremstilling av D-pantotensyre og/eller salter som tilsetning til dyrefôr
NO20033706D0 (no)	2003-08-20	Fremgangsmåte for fremstilling av D-pantotensyre og/eller salter som tilsetning til dyrefôr