NO20061083L - Kombinasjoner omfattende alfa-2-delta ligander og serotonin/noradrenalin gjenopptaksinhibitorer - Google Patents
Kombinasjoner omfattende alfa-2-delta ligander og serotonin/noradrenalin gjenopptaksinhibitorerInfo
- Publication number
- NO20061083L NO20061083L NO20061083A NO20061083A NO20061083L NO 20061083 L NO20061083 L NO 20061083L NO 20061083 A NO20061083 A NO 20061083A NO 20061083 A NO20061083 A NO 20061083A NO 20061083 L NO20061083 L NO 20061083L
- Authority
- NO
- Norway
- Prior art keywords
- serotonin
- alpha
- noradrenaline reuptake
- combinations
- reuptake inhibitors
- Prior art date
Links
- 239000002767 noradrenalin uptake inhibitor Substances 0.000 title abstract 3
- 239000003446 ligand Substances 0.000 title abstract 2
- QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 title 2
- 229940076279 serotonin Drugs 0.000 title 1
- 239000003772 serotonin uptake inhibitor Substances 0.000 title 1
- 229940126569 noradrenaline reuptake inhibitor Drugs 0.000 abstract 2
- 229940124834 selective serotonin reuptake inhibitor Drugs 0.000 abstract 2
- 239000012896 selective serotonin reuptake inhibitor Substances 0.000 abstract 2
- 208000002193 Pain Diseases 0.000 abstract 1
- 230000009977 dual effect Effects 0.000 abstract 1
- 208000004296 neuralgia Diseases 0.000 abstract 1
- 208000021722 neuropathic pain Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000011885 synergistic combination Substances 0.000 abstract 1
Classifications
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
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- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
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- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
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- Pain & Pain Management (AREA)
- Physical Education & Sports Medicine (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Virology (AREA)
- Addiction (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Nutrition Science (AREA)
- Obesity (AREA)
- Psychology (AREA)
- Immunology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Psychiatry (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
Abstract
Foreliggende oppfinnelse angår en kombinasjon, spesielt en synergistisk kombinasjon, av en alfa-2-delta-ligand og en dual serotonin-noradrenalin gjenopptaksinhibitor (DSNRI) eller én eller begge av en selektiv serotonin-gjenopptaksinhibitor (SSRI) og en selektiv noradrenalin gjenopptaksinhibitor (SNRI) og farmasøytisk akseptable salter derav, farmasøytiske preparater derav og anvendelse av dem ved behandling av smerte, spesielt nevropatisk smerte.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50255603P | 2003-09-12 | 2003-09-12 | |
| PCT/IB2004/002943 WO2005025675A1 (en) | 2003-09-12 | 2004-09-06 | Combinations comprising alpha-2-delta ligands and serotonin / noradrenaline re-uptake inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20061083L true NO20061083L (no) | 2006-06-06 |
Family
ID=34312404
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20061083A NO20061083L (no) | 2003-09-12 | 2006-03-06 | Kombinasjoner omfattende alfa-2-delta ligander og serotonin/noradrenalin gjenopptaksinhibitorer |
Country Status (21)
| Country | Link |
|---|---|
| US (4) | US20050059715A1 (no) |
| EP (2) | EP2156863A3 (no) |
| JP (2) | JP2007505097A (no) |
| KR (1) | KR100828218B1 (no) |
| CN (1) | CN1849153A (no) |
| AR (1) | AR045634A1 (no) |
| AT (1) | ATE449633T1 (no) |
| AU (2) | AU2004271800A1 (no) |
| BR (1) | BRPI0414343A (no) |
| CA (1) | CA2537402C (no) |
| CO (1) | CO5660280A2 (no) |
| DE (1) | DE602004024317D1 (no) |
| ES (1) | ES2334673T3 (no) |
| IL (1) | IL173904A0 (no) |
| MX (1) | MXPA06002789A (no) |
| NO (1) | NO20061083L (no) |
| NZ (1) | NZ545494A (no) |
| RU (1) | RU2320369C2 (no) |
| TW (1) | TW200526249A (no) |
| WO (1) | WO2005025675A1 (no) |
| ZA (1) | ZA200602077B (no) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL126999A (en) | 1996-07-24 | 2002-03-10 | Warner Lambert Co | Pharmaceutical preparations containing isobutylgaba and its history for use in the treatment of pain |
| US7704527B2 (en) * | 2002-10-25 | 2010-04-27 | Collegium Pharmaceutical, Inc. | Modified release compositions of milnacipran |
| BRPI0511941A (pt) * | 2004-06-09 | 2008-01-22 | Pfizer | uso de (s, s)-reboxetina ou reboxetina racêmica |
| WO2007088473A2 (en) * | 2006-02-03 | 2007-08-09 | Neurocure Ltd | Treatment and prevention of depression with pain, depression secondary to pain, and of neuropathic pain |
| TW200914457A (en) * | 2007-05-31 | 2009-04-01 | Kyowa Hakko Kogyo Kk | Pyrimidodiazepinone derivative |
| WO2009136375A1 (en) * | 2008-05-08 | 2009-11-12 | Pfizer Inc | Treatment of interstitial cystitis |
| EP2123626A1 (en) * | 2008-05-21 | 2009-11-25 | Laboratorios del Dr. Esteve S.A. | Co-crystals of duloxetine and co-crystal formers for the treatment of pain |
| PT2453910T (pt) * | 2009-07-15 | 2016-12-07 | Portola Pharm Inc | Formulação de dose unitária de antídoto contra inibidores de fator xa para uso na prevenção de sangramento |
| CA2805371C (en) | 2010-07-30 | 2017-10-31 | Toray Industries, Inc. | Therapeutic agent or prophylactic agent for neuropathic pain |
| US10576045B2 (en) | 2011-02-16 | 2020-03-03 | Nir Barak | Low dosage combinations of fluoxetine and reboxetine for treating obesity |
| WO2014112152A1 (ja) * | 2013-01-18 | 2014-07-24 | 有限会社ケムフィズ | 神経因性疾病の治療のための医薬 |
| JP6491213B2 (ja) * | 2013-12-18 | 2019-03-27 | ノヴァッセイ エスエー | 疼痛および他の障害の治療のためのガンマ−アミノ酪酸(gaba)類似体 |
| BR112018007374B1 (pt) | 2015-10-22 | 2023-11-28 | Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. | Composição farmacêutica |
| IT201900006602A1 (it) | 2019-05-07 | 2020-11-07 | Acraf | Composizione farmaceutica per il trattamento del dolore neuropatico |
Family Cites Families (72)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3454554A (en) | 1960-10-14 | 1969-07-08 | Colgate Palmolive Co | Aminoalkyliminodibenzyl compounds |
| BE674185A (no) | 1961-10-10 | |||
| US3198834A (en) | 1964-07-27 | 1965-08-03 | Snc Science Union Et Compagnie | Optical isomers of trifluoromethylated phenethylamines |
| NL129434C (no) | 1966-03-12 | |||
| GB1177525A (en) | 1967-04-13 | 1970-01-14 | Leo Ab | New Heterocyclic Aminoketones of Therapeutic Interest |
| US3885046A (en) | 1969-12-04 | 1975-05-20 | Burroughs Wellcome Co | Meta chloro or fluoro substituted alpha-T-butylaminopropionphenones in the treatment of depression |
| BE759838A (fr) | 1969-12-04 | 1971-06-03 | Wellcome Found | Cetones a activite biologique |
| GB1422263A (en) | 1973-01-30 | 1976-01-21 | Ferrosan As | 4-phenyl-piperidine compounds |
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-
2004
- 2004-09-06 NZ NZ545494A patent/NZ545494A/en not_active IP Right Cessation
- 2004-09-06 AU AU2004271800A patent/AU2004271800A1/en not_active Abandoned
- 2004-09-06 RU RU2006107552/15A patent/RU2320369C2/ru not_active IP Right Cessation
- 2004-09-06 CN CNA2004800261754A patent/CN1849153A/zh active Pending
- 2004-09-06 DE DE602004024317T patent/DE602004024317D1/de not_active Expired - Lifetime
- 2004-09-06 EP EP09176933A patent/EP2156863A3/en not_active Ceased
- 2004-09-06 MX MXPA06002789A patent/MXPA06002789A/es active IP Right Grant
- 2004-09-06 BR BRPI0414343-4A patent/BRPI0414343A/pt not_active IP Right Cessation
- 2004-09-06 KR KR1020067004976A patent/KR100828218B1/ko not_active Expired - Fee Related
- 2004-09-06 CA CA002537402A patent/CA2537402C/en not_active Expired - Fee Related
- 2004-09-06 JP JP2006525924A patent/JP2007505097A/ja not_active Withdrawn
- 2004-09-06 ES ES04769341T patent/ES2334673T3/es not_active Expired - Lifetime
- 2004-09-06 EP EP04769341A patent/EP1663398B1/en not_active Expired - Lifetime
- 2004-09-06 AT AT04769341T patent/ATE449633T1/de not_active IP Right Cessation
- 2004-09-06 WO PCT/IB2004/002943 patent/WO2005025675A1/en not_active Ceased
- 2004-09-08 US US10/935,824 patent/US20050059715A1/en not_active Abandoned
- 2004-09-10 TW TW093127537A patent/TW200526249A/zh unknown
- 2004-09-10 AR ARP040103262A patent/AR045634A1/es not_active Application Discontinuation
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2006
- 2006-02-23 IL IL173904A patent/IL173904A0/en unknown
- 2006-03-03 CO CO06021162A patent/CO5660280A2/es not_active Application Discontinuation
- 2006-03-06 NO NO20061083A patent/NO20061083L/no not_active Application Discontinuation
- 2006-03-10 ZA ZA200602077A patent/ZA200602077B/en unknown
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2009
- 2009-12-02 US US12/629,516 patent/US20100081718A1/en not_active Abandoned
-
2011
- 2011-02-21 AU AU2011200717A patent/AU2011200717A1/en not_active Abandoned
-
2012
- 2012-03-07 JP JP2012049988A patent/JP2012144545A/ja not_active Withdrawn
- 2012-08-29 US US13/597,462 patent/US20120329781A1/en not_active Abandoned
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2014
- 2014-03-19 US US14/219,351 patent/US20140206670A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0414343A (pt) | 2006-11-07 |
| EP1663398A1 (en) | 2006-06-07 |
| US20140206670A1 (en) | 2014-07-24 |
| EP2156863A3 (en) | 2011-01-12 |
| WO2005025675A1 (en) | 2005-03-24 |
| JP2012144545A (ja) | 2012-08-02 |
| RU2320369C2 (ru) | 2008-03-27 |
| RU2006107552A (ru) | 2007-09-20 |
| KR20060082861A (ko) | 2006-07-19 |
| ATE449633T1 (de) | 2009-12-15 |
| CN1849153A (zh) | 2006-10-18 |
| US20100081718A1 (en) | 2010-04-01 |
| NZ545494A (en) | 2009-10-30 |
| CO5660280A2 (es) | 2006-07-31 |
| MXPA06002789A (es) | 2006-06-14 |
| KR100828218B1 (ko) | 2008-05-07 |
| ZA200602077B (en) | 2007-06-27 |
| AR045634A1 (es) | 2005-11-02 |
| US20120329781A1 (en) | 2012-12-27 |
| AU2011200717A1 (en) | 2011-03-10 |
| CA2537402C (en) | 2009-05-05 |
| CA2537402A1 (en) | 2005-03-24 |
| ES2334673T3 (es) | 2010-03-15 |
| US20050059715A1 (en) | 2005-03-17 |
| DE602004024317D1 (de) | 2010-01-07 |
| TW200526249A (en) | 2005-08-16 |
| IL173904A0 (en) | 2006-07-05 |
| AU2004271800A1 (en) | 2005-03-24 |
| EP1663398B1 (en) | 2009-11-25 |
| EP2156863A2 (en) | 2010-02-24 |
| JP2007505097A (ja) | 2007-03-08 |
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