ATE409465T1 - Parenteral verabreichbare mikropartikel- zubereitung mit kontrollierter freisetzung - Google Patents

Parenteral verabreichbare mikropartikel- zubereitung mit kontrollierter freisetzung

Info

Publication number
ATE409465T1
ATE409465T1 AT01975100T AT01975100T ATE409465T1 AT E409465 T1 ATE409465 T1 AT E409465T1 AT 01975100 T AT01975100 T AT 01975100T AT 01975100 T AT01975100 T AT 01975100T AT E409465 T1 ATE409465 T1 AT E409465T1
Authority
AT
Austria
Prior art keywords
controlled release
microparticle preparation
parenterally administered
curve
release
Prior art date
Application number
AT01975100T
Other languages
English (en)
Inventor
Mats Reslow
Soeren Bjoern
Joern Drustrup
Nils Gustafsson
Monica Joensson
Timo Laakso
Original Assignee
Pacira Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE0003614A external-priority patent/SE517610C2/sv
Application filed by Pacira Pharmaceuticals Inc filed Critical Pacira Pharmaceuticals Inc
Application granted granted Critical
Publication of ATE409465T1 publication Critical patent/ATE409465T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/27Growth hormone [GH], i.e. somatotropin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991Coated

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT01975100T 2000-10-06 2001-10-05 Parenteral verabreichbare mikropartikel- zubereitung mit kontrollierter freisetzung ATE409465T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0003614A SE517610C2 (sv) 2000-10-06 2000-10-06 Mikropartikelberedning
US26049501P 2001-01-08 2001-01-08

Publications (1)

Publication Number Publication Date
ATE409465T1 true ATE409465T1 (de) 2008-10-15

Family

ID=26655254

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01975100T ATE409465T1 (de) 2000-10-06 2001-10-05 Parenteral verabreichbare mikropartikel- zubereitung mit kontrollierter freisetzung

Country Status (8)

Country Link
US (1) US7033609B2 (de)
EP (1) EP1328258B1 (de)
JP (1) JP2004510730A (de)
AT (1) ATE409465T1 (de)
AU (1) AU2001294459A1 (de)
CA (1) CA2424896A1 (de)
DE (1) DE60136002D1 (de)
WO (1) WO2002028375A1 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6956021B1 (en) * 1998-08-25 2005-10-18 Advanced Inhalation Research, Inc. Stable spray-dried protein formulations
FR2861734B1 (fr) 2003-04-10 2006-04-14 Corneal Ind Reticulation de polysaccharides de faible et forte masse moleculaire; preparation d'hydrogels monophasiques injectables; polysaccharides et hydrogels obtenus
EP1726299A3 (de) * 2005-05-27 2007-04-18 StratoSphere Pharma AB Kerne und Mikrokapsel zur parenteralen Verabreichung sowie Verfahren zu deren Herstellung
US8017152B2 (en) 2005-05-27 2011-09-13 Stratosphere Pharma Ab Cores and microcapsules suitable for parenteral administration as well as process for their manufacture
EP2152743A2 (de) * 2007-05-23 2010-02-17 Allergan, Inc. Quervernetztes collagen und anwendungen davon
BRPI0811777A2 (pt) * 2007-05-23 2019-09-24 Allergan Inc partículas de ácido hialurõnico revestidas
US8318695B2 (en) * 2007-07-30 2012-11-27 Allergan, Inc. Tunably crosslinked polysaccharide compositions
US8697044B2 (en) 2007-10-09 2014-04-15 Allergan, Inc. Crossed-linked hyaluronic acid and collagen and uses thereof
EP2818184B1 (de) 2007-11-16 2018-10-31 Allergan, Inc. Zusammensetzungen Und Verfahren Zur Behandlung Von Purpura
US8394782B2 (en) 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having increased longevity
US20090143348A1 (en) * 2007-11-30 2009-06-04 Ahmet Tezel Polysaccharide gel compositions and methods for sustained delivery of drugs
US8394784B2 (en) * 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having multi-stage bioactive agent delivery
US8357795B2 (en) 2008-08-04 2013-01-22 Allergan, Inc. Hyaluronic acid-based gels including lidocaine
WO2010028025A1 (en) 2008-09-02 2010-03-11 Gurtner Geoffrey C Threads of hyaluronic acid and/or derivatives thereof, methods of making thereof and uses thereof
CN101574638B (zh) * 2009-06-15 2012-04-18 中国农业大学 一种淀粉纳米微球及其制备方法
US9114188B2 (en) 2010-01-13 2015-08-25 Allergan, Industrie, S.A.S. Stable hydrogel compositions including additives
US20110172180A1 (en) 2010-01-13 2011-07-14 Allergan Industrie. Sas Heat stable hyaluronic acid compositions for dermatological use
US20110171311A1 (en) * 2010-01-13 2011-07-14 Allergan Industrie, Sas Stable hydrogel compositions including additives
US20110171286A1 (en) * 2010-01-13 2011-07-14 Allergan, Inc. Hyaluronic acid compositions for dermatological use
US20130052647A1 (en) * 2010-02-10 2013-02-28 Marianna Goldrick Methods for fractionating and processing microparticles from biological samples and using them for biomarker discovery
EP2544652A2 (de) * 2010-03-12 2013-01-16 Allergan Industrie SAS Fluidzusammensetzung mit einem hyaluronanpolymer und mannitol zur verbesserung des hautzustandes
EP3520827B1 (de) 2010-03-22 2022-05-25 Allergan, Inc. Vernetzte hydrogele zur weichgewebevergrösserung
US8883139B2 (en) 2010-08-19 2014-11-11 Allergan Inc. Compositions and soft tissue replacement methods
US8697057B2 (en) 2010-08-19 2014-04-15 Allergan, Inc. Compositions and soft tissue replacement methods
US8889123B2 (en) 2010-08-19 2014-11-18 Allergan, Inc. Compositions and soft tissue replacement methods
US9005605B2 (en) 2010-08-19 2015-04-14 Allergan, Inc. Compositions and soft tissue replacement methods
US9393263B2 (en) 2011-06-03 2016-07-19 Allergan, Inc. Dermal filler compositions including antioxidants
US9149422B2 (en) 2011-06-03 2015-10-06 Allergan, Inc. Dermal filler compositions including antioxidants
US20130096081A1 (en) 2011-06-03 2013-04-18 Allergan, Inc. Dermal filler compositions
US9408797B2 (en) 2011-06-03 2016-08-09 Allergan, Inc. Dermal filler compositions for fine line treatment
US20130244943A1 (en) 2011-09-06 2013-09-19 Allergan, Inc. Hyaluronic acid-collagen matrices for dermal filling and volumizing applications
US9662422B2 (en) 2011-09-06 2017-05-30 Allergan, Inc. Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
EP3200838B1 (de) 2014-09-30 2019-09-18 Allergan Industrie, SAS Stabile hydrogelzusammensetzungen mit additiven
WO2016128783A1 (en) 2015-02-09 2016-08-18 Allergan Industrie Sas Compositions and methods for improving skin appearance
WO2016128550A1 (en) 2015-02-13 2016-08-18 Allergan Industrie, Sas Implants for sculpting, augmenting or correcting facial features such as the chin

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE744162A (fr) 1969-01-16 1970-06-15 Fuji Photo Film Co Ltd Procede d'encapsulage
US3881991A (en) 1969-01-24 1975-05-06 Hayashibara Co Process for producing amylose powders having a mean degree of polymerization between 20{14 30
DE2010115A1 (de) 1970-03-04 1971-09-16 Farbenfabriken Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung von Mikrogranulaten
US4389330A (en) 1980-10-06 1983-06-21 Stolle Research And Development Corporation Microencapsulation process
US4713249A (en) 1981-11-12 1987-12-15 Schroeder Ulf Crystallized carbohydrate matrix for biologically active substances, a process of preparing said matrix, and the use thereof
SE459005B (sv) 1985-07-12 1989-05-29 Aake Rikard Lindahl Saett att framstaella sfaeriska polymerpartiklar
GB2209937B (en) * 1987-09-21 1991-07-03 Depiopharm S A Water insoluble polypeptides
JP2670680B2 (ja) 1988-02-24 1997-10-29 株式会社ビーエムジー 生理活性物質含有ポリ乳酸系微小球およびその製造法
US5019400A (en) 1989-05-01 1991-05-28 Enzytech, Inc. Very low temperature casting of controlled release microspheres
ES2084698T5 (es) 1989-05-04 2005-03-01 Southern Research Institute Procedimiento de encapsulacion.
DK168790D0 (de) 1990-07-13 1990-07-13 Novo Nordisk As
EP0535937B2 (de) 1991-10-01 2008-05-21 Takeda Chemical Industries, Ltd. Mikropartikeln-Zusammenfassung zur verlängerten Freigabe und Herstellung derselbe
US5470582A (en) 1992-02-07 1995-11-28 Syntex (U.S.A.) Inc. Controlled delivery of pharmaceuticals from preformed porous polymeric microparticles
WO1993021008A1 (en) 1992-04-20 1993-10-28 Redding Bruce K Jr Method and apparatus for the modification of starch and other polymers
JPH08503950A (ja) 1992-12-02 1996-04-30 アルカーメス・コントロールド・セラピユーテイクス・インコーポレーテツド 徐放性成長ホルモン含有マイクロスフェア
US5981719A (en) 1993-03-09 1999-11-09 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
CA2157793C (en) 1993-03-09 1999-07-13 James E. Woiszwillo Macromolecular microparticles and methods of production
DE4434877A1 (de) 1994-09-29 1996-04-04 Fresenius Ag Verfahren zur Herstellung von Stärkeabbauprodukten
KR100201352B1 (ko) 1995-03-16 1999-06-15 성재갑 단일주사 백신 제형
US5942253A (en) * 1995-10-12 1999-08-24 Immunex Corporation Prolonged release of GM-CSF
SE505146C2 (sv) * 1995-10-19 1997-06-30 Biogram Ab Partiklar för fördröjd frisättning
US5959102A (en) 1997-06-30 1999-09-28 Rutgers University Starch purification by thermally tolerant broad pH range proteolytic enzymes
SE512663C2 (sv) 1997-10-23 2000-04-17 Biogram Ab Inkapslingsförfarande för aktiv substans i en bionedbrytbar polymer
JPH11302156A (ja) 1998-04-16 1999-11-02 Tanabe Seiyaku Co Ltd ポリペプチドの微粒子化方法
SE517422C2 (sv) * 2000-10-06 2002-06-04 Bioglan Ab Farmaceutiskt acceptabel stärkelse

Also Published As

Publication number Publication date
EP1328258B1 (de) 2008-10-01
WO2002028375A1 (en) 2002-04-11
US7033609B2 (en) 2006-04-25
AU2001294459A1 (en) 2002-04-15
JP2004510730A (ja) 2004-04-08
EP1328258A1 (de) 2003-07-23
CA2424896A1 (en) 2002-04-11
US20020102311A1 (en) 2002-08-01
DE60136002D1 (de) 2008-11-13

Similar Documents

Publication Publication Date Title
ATE409465T1 (de) Parenteral verabreichbare mikropartikel- zubereitung mit kontrollierter freisetzung
DE58909072D1 (en) Alloplastisches implantat.
CA2207286A1 (en) Localized delivery of factors enhancing survival of transplanted cells
HU9501942D0 (en) Microencapsulated 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles
DK1137400T3 (da) Præparater indeholdende et peptid og polymælkesyre-glycolsyre egnet til fremstilling af subkutane implantater med en forlænget frigivelsesperiode
UA29563C2 (uk) Мікрокапсула для тривалого вивільнення фізіологічно активного пептиду
GEP20022707B (en) Biodegrading Macromers for the Controlled Release of Biologically Active Substances
HU9700322D0 (en) Local anesthetics and compositions and methods
MY113488A (en) Compounds with growth hormone releasing properties
HRP20020929A2 (en) Sustained release pharmaceutical cmpositions for parenteral administration of hydrophilic compounds
ATE266988T1 (de) Kompresionsstrumpf oder -strumpfhose
IL115138A (en) Implantable polymer-containing molded articles for the administration of active substances to plants and processes for the preparation thereof
DE59909717D1 (de) Verfahren zur Herstellung von festen Dosierungsformen
NZ515999A (en) Biologically active materials
ATE217800T1 (de) Bioabbaubare, injizierbare oligomer-polymer- zusammensetzung
IT1293088B1 (it) Microparticelle per il rilascio controllato di molecole biologicamente attive e loro uso in terapia, profilassi e diagnostica in vitro e in
WO2000019997A8 (en) Controlled release dosage from comprising oxybutynin
SE0003614L (sv) Mikropartikelberedning
Magnin et al. Hepatitis caused by micronized natural progesterone given for preterm labor
RU96109846A (ru) Способ профилактики генерализации септической инфекции в раннем послеродовом периоде
WO2002018593A3 (en) Modulation of fas and fasl expression

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties