ATE411390T1 - Synthetische säugetier alpha-n- acetylglukosaminidase und dafür kodierende genetische sequenzen - Google Patents

Synthetische säugetier alpha-n- acetylglukosaminidase und dafür kodierende genetische sequenzen

Info

Publication number
ATE411390T1
ATE411390T1 AT96938846T AT96938846T ATE411390T1 AT E411390 T1 ATE411390 T1 AT E411390T1 AT 96938846 T AT96938846 T AT 96938846T AT 96938846 T AT96938846 T AT 96938846T AT E411390 T1 ATE411390 T1 AT E411390T1
Authority
AT
Austria
Prior art keywords
synthetic
genetic sequences
sequences coding
acetyl glucosaminidase
mammal alpha
Prior art date
Application number
AT96938846T
Other languages
English (en)
Inventor
John Hopwood
Hamish Scott
Birgit Weber
Lianne Blanch
Donald Anson
Original Assignee
Womens & Childrens Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Womens & Childrens Hospital filed Critical Womens & Childrens Hospital
Application granted granted Critical
Publication of ATE411390T1 publication Critical patent/ATE411390T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/0105—Alpha-N-acetylglucosaminidase (3.2.1.50)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT96938846T 1995-11-23 1996-11-22 Synthetische säugetier alpha-n- acetylglukosaminidase und dafür kodierende genetische sequenzen ATE411390T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AUPN6748A AUPN674895A0 (en) 1995-11-23 1995-11-23 Synthetic mammalian alpha-N-acetylglucosaminidase and genetic sequences encoding same

Publications (1)

Publication Number Publication Date
ATE411390T1 true ATE411390T1 (de) 2008-10-15

Family

ID=3791070

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96938846T ATE411390T1 (de) 1995-11-23 1996-11-22 Synthetische säugetier alpha-n- acetylglukosaminidase und dafür kodierende genetische sequenzen

Country Status (10)

Country Link
US (3) US6255096B1 (de)
EP (2) EP2048235A3 (de)
JP (1) JP2000500972A (de)
AT (1) ATE411390T1 (de)
AU (1) AUPN674895A0 (de)
DE (1) DE69637715D1 (de)
DK (1) DK0870036T3 (de)
ES (1) ES2319828T3 (de)
PT (1) PT870036E (de)
WO (1) WO1997019177A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1261379A2 (de) * 2000-02-17 2002-12-04 Genzyme Corporation Lungentransfektion als genverabreichungsmethode
JP5415283B2 (ja) * 2007-02-07 2014-02-12 グラダリス インク． シアル酸産生を調節し、遺伝性封入体ミオパチーを治療する方法及び組成物
WO2009131698A2 (en) * 2008-04-23 2009-10-29 Iowa State University Research Foundation, Inc. PHOSPHORYLATED RECOMBINANT N-ACETYL-alpha-D- GLUCOSAMINIDASE (NaGlu) AND USES THEREOF
BR112012033214B1 (pt) 2010-06-25 2020-11-03 Shire Human Genetic Therapies, Inc. uso de uma formulação estável compreendendo uma proteína de iduronato-2-sulfatase (i2s), formulação compreendendo a mesma e recipiente
EP2596123B1 (de) 2010-07-22 2015-11-25 Shire Human Genetic Therapies, Inc. Kristallstruktur einer humanen alpha-n-acetylglucosaminidase
ES2679374T3 (es) 2012-11-27 2018-08-24 Biomarin Pharmaceutical Inc. Proteínas de fusión terapéuticas dirigidas de enzima lisosómica y usos de las mismas
CA3192771A1 (en) 2020-08-28 2022-03-03 Jcr Pharmaceuticals Co., Ltd. Mutant of .alpha.-n-acetylglucosaminidase

Also Published As

Publication number Publication date
EP2048235A3 (de) 2009-04-22
EP0870036A1 (de) 1998-10-14
EP0870036B1 (de) 2008-10-15
US6255096B1 (en) 2001-07-03
EP0870036A4 (de) 2000-01-19
DK0870036T3 (da) 2008-11-24
DE69637715D1 (de) 2008-11-27
ES2319828T3 (es) 2009-05-12
US7604958B2 (en) 2009-10-20
AUPN674895A0 (en) 1995-12-14
EP2048235A2 (de) 2009-04-15
JP2000500972A (ja) 2000-02-02
US20070212769A1 (en) 2007-09-13
US20030039643A1 (en) 2003-02-27
PT870036E (pt) 2009-01-22
WO1997019177A1 (en) 1997-05-29

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