DK0870036T3 - Syntetisk pattedyrs-alfa-N-acetylglucosaminidase og genetiske sekvenser kodende derfor - Google Patents
Syntetisk pattedyrs-alfa-N-acetylglucosaminidase og genetiske sekvenser kodende derforInfo
- Publication number
- DK0870036T3 DK0870036T3 DK96938846T DK96938846T DK0870036T3 DK 0870036 T3 DK0870036 T3 DK 0870036T3 DK 96938846 T DK96938846 T DK 96938846T DK 96938846 T DK96938846 T DK 96938846T DK 0870036 T3 DK0870036 T3 DK 0870036T3
- Authority
- DK
- Denmark
- Prior art keywords
- acetylglucosaminidase
- encoding
- genetic sequences
- mammalian alpha
- synthetic mammalian
- Prior art date
Links
- 230000002068 genetic effect Effects 0.000 title abstract 2
- 102100034561 Alpha-N-acetylglucosaminidase Human genes 0.000 title 1
- 108010009380 alpha-N-acetyl-D-glucosaminidase Proteins 0.000 title 1
- 230000007812 deficiency Effects 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 238000011835 investigation Methods 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/0105—Alpha-N-acetylglucosaminidase (3.2.1.50)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPN6748A AUPN674895A0 (en) | 1995-11-23 | 1995-11-23 | Synthetic mammalian alpha-N-acetylglucosaminidase and genetic sequences encoding same |
| PCT/AU1996/000747 WO1997019177A1 (en) | 1995-11-23 | 1996-11-22 | SYNTHETIC MAMMALIAN α-N-ACETYLGLUCOSAMINIDASE AND GENETIC SEQUENCES ENCODING SAME |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0870036T3 true DK0870036T3 (da) | 2008-11-24 |
Family
ID=3791070
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96938846T DK0870036T3 (da) | 1995-11-23 | 1996-11-22 | Syntetisk pattedyrs-alfa-N-acetylglucosaminidase og genetiske sekvenser kodende derfor |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US6255096B1 (da) |
| EP (2) | EP2048235A3 (da) |
| JP (1) | JP2000500972A (da) |
| AT (1) | ATE411390T1 (da) |
| AU (1) | AUPN674895A0 (da) |
| DE (1) | DE69637715D1 (da) |
| DK (1) | DK0870036T3 (da) |
| ES (1) | ES2319828T3 (da) |
| PT (1) | PT870036E (da) |
| WO (1) | WO1997019177A1 (da) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1261379A2 (en) * | 2000-02-17 | 2002-12-04 | Genzyme Corporation | Genetic modification of the lung as a portal for gene delivery |
| JP5415283B2 (ja) * | 2007-02-07 | 2014-02-12 | グラダリス インク． | シアル酸産生を調節し、遺伝性封入体ミオパチーを治療する方法及び組成物 |
| WO2009131698A2 (en) * | 2008-04-23 | 2009-10-29 | Iowa State University Research Foundation, Inc. | PHOSPHORYLATED RECOMBINANT N-ACETYL-alpha-D- GLUCOSAMINIDASE (NaGlu) AND USES THEREOF |
| BR112012033214B1 (pt) | 2010-06-25 | 2020-11-03 | Shire Human Genetic Therapies, Inc. | uso de uma formulação estável compreendendo uma proteína de iduronato-2-sulfatase (i2s), formulação compreendendo a mesma e recipiente |
| EP2596123B1 (en) | 2010-07-22 | 2015-11-25 | Shire Human Genetic Therapies, Inc. | Crystal structure of human alpha-n-acetylglucosaminidase |
| ES2679374T3 (es) | 2012-11-27 | 2018-08-24 | Biomarin Pharmaceutical Inc. | Proteínas de fusión terapéuticas dirigidas de enzima lisosómica y usos de las mismas |
| CA3192771A1 (en) | 2020-08-28 | 2022-03-03 | Jcr Pharmaceuticals Co., Ltd. | Mutant of .alpha.-n-acetylglucosaminidase |
-
1995
- 1995-11-23 AU AUPN6748A patent/AUPN674895A0/en not_active Abandoned
-
1996
- 1996-11-22 AT AT96938846T patent/ATE411390T1/de active
- 1996-11-22 DE DE69637715T patent/DE69637715D1/de not_active Expired - Lifetime
- 1996-11-22 EP EP08165866A patent/EP2048235A3/en not_active Withdrawn
- 1996-11-22 JP JP9519238A patent/JP2000500972A/ja active Pending
- 1996-11-22 US US09/077,354 patent/US6255096B1/en not_active Expired - Lifetime
- 1996-11-22 EP EP96938846A patent/EP0870036B1/en not_active Expired - Lifetime
- 1996-11-22 WO PCT/AU1996/000747 patent/WO1997019177A1/en not_active Ceased
- 1996-11-22 ES ES96938846T patent/ES2319828T3/es not_active Expired - Lifetime
- 1996-11-22 DK DK96938846T patent/DK0870036T3/da active
- 1996-11-22 PT PT96938846T patent/PT870036E/pt unknown
-
2001
- 2001-04-17 US US09/836,613 patent/US20030039643A1/en not_active Abandoned
-
2007
- 2007-01-25 US US11/657,766 patent/US7604958B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP2048235A3 (en) | 2009-04-22 |
| EP0870036A1 (en) | 1998-10-14 |
| EP0870036B1 (en) | 2008-10-15 |
| US6255096B1 (en) | 2001-07-03 |
| EP0870036A4 (en) | 2000-01-19 |
| DE69637715D1 (de) | 2008-11-27 |
| ES2319828T3 (es) | 2009-05-12 |
| US7604958B2 (en) | 2009-10-20 |
| AUPN674895A0 (en) | 1995-12-14 |
| EP2048235A2 (en) | 2009-04-15 |
| JP2000500972A (ja) | 2000-02-02 |
| US20070212769A1 (en) | 2007-09-13 |
| ATE411390T1 (de) | 2008-10-15 |
| US20030039643A1 (en) | 2003-02-27 |
| PT870036E (pt) | 2009-01-22 |
| WO1997019177A1 (en) | 1997-05-29 |
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