ATE412640T1 - Verfahren zur gewinnung eines zur gewinnung von valsartan nützlichen valsartan-salzes - Google Patents

Verfahren zur gewinnung eines zur gewinnung von valsartan nützlichen valsartan-salzes

Info

Publication number: ATE412640T1
Authority: AT; Austria
Prior art keywords: valsartan; obtaining; salt; dilithium salt; salt useful
Prior art date: 2007-06-07

Application number

AT07380165T

Other languages

English (en)

Inventor

Clotet Joan Huguet

Barjoan Pere Dalmases

Original Assignee

Inke Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-06-07

Filing date

2007-06-07

Publication date

2008-11-15

2007-06-07 Application filed by Inke Sa filed Critical Inke Sa

2008-11-15 Application granted granted Critical

2008-11-15 Publication of ATE412640T1 publication Critical patent/ATE412640T1/de

Links

SJSNUMAYCRRIOM-QFIPXVFZSA-N valsartan Chemical class C1=CC(CN(C(=O)CCCC)[C@@H](C(C)C)C(O)=O)=CC=C1C1=CC=CC=C1C1=NN=N[N]1 SJSNUMAYCRRIOM-QFIPXVFZSA-N 0.000 title abstract 7
239000004072 C09CA03 - Valsartan Substances 0.000 title abstract 6
229960004699 valsartan Drugs 0.000 title abstract 6
238000000034 method Methods 0.000 title abstract 2
SMBQBQBNOXIFSF-UHFFFAOYSA-N dilithium Chemical class [Li][Li] SMBQBQBNOXIFSF-UHFFFAOYSA-N 0.000 abstract 3
KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 abstract 2
230000008878 coupling Effects 0.000 abstract 2
238000010168 coupling process Methods 0.000 abstract 2
238000005859 coupling reaction Methods 0.000 abstract 2
WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 abstract 1
239000003054 catalyst Substances 0.000 abstract 1
150000004677 hydrates Chemical class 0.000 abstract 1
229910052744 lithium Inorganic materials 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
239000003960 organic solvent Substances 0.000 abstract 1
229910052763 palladium Inorganic materials 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000012453 solvate Substances 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

AT07380165T 2007-06-07 2007-06-07 Verfahren zur gewinnung eines zur gewinnung von valsartan nützlichen valsartan-salzes ATE412640T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP07380165A EP1849777B1 (de)	2007-06-07	2007-06-07	Verfahren zur Gewinnung eines zur Gewinnung von Valsartan nützlichen Valsartan-Salzes

Publications (1)

Publication Number	Publication Date
ATE412640T1 true ATE412640T1 (de)	2008-11-15

Family

ID=38473039

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT07380165T ATE412640T1 (de)	2007-06-07	2007-06-07	Verfahren zur gewinnung eines zur gewinnung von valsartan nützlichen valsartan-salzes

Country Status (7)

Country	Link
EP (1)	EP1849777B1 (de)
JP (1)	JP2010538971A (de)
KR (1)	KR20100020513A (de)
AT (1)	ATE412640T1 (de)
DE (1)	DE602007000211D1 (de)
ES (1)	ES2312162T3 (de)
WO (1)	WO2008148599A2 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPWO2012002189A1 (ja) *	2010-06-30	2013-08-22	株式会社トクヤマ	バルサルタンの製造方法
CN104030996B (zh) *	2014-05-21	2016-06-01	丽珠医药集团股份有限公司	一种缬沙坦的合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE122007000050I1 (de) *	1990-02-19	2007-11-08	Novartis Ag	Acylverbindungen
AR032758A1 (es) *	2000-07-19	2003-11-26	Novartis Ag	Sales valsartan, un proceso para su fabricacion, composiciones farmaceuticas y el uso de dichas sales para la preparacion de medicamentos
ES2251292B1 (es) *	2004-04-20	2007-07-01	Inke, S.A.	Procedimiento para la obtencion de un compuesto farmaceuticamente activo y de sus intermedios de sintesis.

2007
- 2007-06-07 EP EP07380165A patent/EP1849777B1/de active Active
- 2007-06-07 DE DE602007000211T patent/DE602007000211D1/de not_active Expired - Fee Related
- 2007-06-07 ES ES07380165T patent/ES2312162T3/es active Active
- 2007-06-07 AT AT07380165T patent/ATE412640T1/de not_active IP Right Cessation
2008
- 2008-04-10 JP JP2010510710A patent/JP2010538971A/ja active Pending
- 2008-04-10 KR KR1020107000321A patent/KR20100020513A/ko not_active Withdrawn
- 2008-04-10 WO PCT/EP2008/054386 patent/WO2008148599A2/en not_active Ceased

Also Published As

Publication number	Publication date
WO2008148599A2 (en)	2008-12-11
EP1849777A1 (de)	2007-10-31
DE602007000211D1 (de)	2008-12-11
KR20100020513A (ko)	2010-02-22
EP1849777B1 (de)	2008-10-29
ES2312162T3 (es)	2009-02-16
WO2008148599A3 (en)	2009-02-26
JP2010538971A (ja)	2010-12-16

Similar Documents

Publication	Publication Date	Title
ATE487702T1 (de)	2010-11-15	Verfahren zum herstellen von 3-dihalomethyl- pyrazol-4-carbonsäurederivaten
NO20082243L (no)	2008-07-21	Fremgangsmater og forbindelser for fremstiliing av CC-1065 analoger
DE602007003024D1 (de)	2009-12-10	Neues verfahren zur salzherstellung
ATE494274T1 (de)	2011-01-15	Verfahren zum herstellen von 2-dihalogenacyl-3- amino-acryls ureestern und 3-dihalogenmethyl- pyrazol-4-carbons ureestern
ATE453634T1 (de)	2010-01-15	Regioselektives verfahren zur zubereitung von benzimidazol-thiophenen
EA200900817A1 (ru)	2009-12-30	Способ получения фторметилзамещённых гетероциклических соединений
EP2123636A4 (de)	2010-12-15	Verfahren zur herstellung eines aminoacetylpyrrolidincarbonitrilderivats
ATE539054T1 (de)	2012-01-15	Verfahren zur herstellung von dihydropyrrolderivaten als zwischenprodukte
MX2009013869A (es)	2010-03-17	Proceso para hacer 2-amino-tiazolonas sustituidas.
WO2008021491A3 (en)	2008-04-17	Method for synthesis of 8-alkoxy-9h-isothiazolo[5,4-b]quinoline-3,4-diones
EA200701470A1 (ru)	2008-02-28	Способы получения производных 4-(фенокси-5-метилпиримидин-4-илокси)пиперидин-1-карбоновой кислоты и родственных соединений
ATE412640T1 (de)	2008-11-15	Verfahren zur gewinnung eines zur gewinnung von valsartan nützlichen valsartan-salzes
ATE532516T1 (de)	2011-11-15	Verfahren zur synthese von glyt-1-hemmern
NZ614088A (en)	2015-02-27	Process for preparing pyridinamines and novel polymorphs thereof
ATE496907T1 (de)	2011-02-15	Verfahren zur herstellung von cilostazol
EP2078709A4 (de)	2009-10-28	Verfahren zur herstellung von olefin
ATE447567T1 (de)	2009-11-15	Verfahren zur herstellung von tryptase- inhibitoren
Sarrafi et al.	2009	Microwave-assisted chemoselective copper-catalyzed amination of o-chloro and o-bromobenzoic acids using aromatic amines under solvent free conditions
ATE443045T1 (de)	2009-10-15	Verfahren zur herstellung von 1-halogen-2,7- naphthyridinylderivaten
ATE423096T1 (de)	2009-03-15	Verfahren zur herstellung von 2- azabicycloä3.3.0üoctan-3-carbonsäurederivaten
ATE555095T1 (de)	2012-05-15	Verfahren zur herstellung von 3-hydroxy-n-alkyl-1-cycloalkyl-6-alkyl-4-oxo-1, -dihydropyridin-2- carbonsäureamid und damit verwandten analoga
ATE473966T1 (de)	2010-07-15	Verfahren zur herstellung eines carbonsäureamidderivats
DE602006013970D1 (de)	2010-06-10	Verfahren zur herstellung substituierter pyrimidine
TW200738647A (en)	2007-10-16	Process for preparing benzimidazole compounds
UA98448C2 (ru)	2012-05-25	Способ получения 2-хлорэтоксиуксусной кислоты n,n-диметиламида, промежуточное соединение и способы его получения

Legal Events

Date	Code	Title	Description
2009-04-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties