ATE416385T1 - Verfahren zur quantifizierung der phosphokinaseaktivität auf proteinen - Google Patents

Verfahren zur quantifizierung der phosphokinaseaktivität auf proteinen

Info

Publication number
ATE416385T1
ATE416385T1 AT01973567T AT01973567T ATE416385T1 AT E416385 T1 ATE416385 T1 AT E416385T1 AT 01973567 T AT01973567 T AT 01973567T AT 01973567 T AT01973567 T AT 01973567T AT E416385 T1 ATE416385 T1 AT E416385T1
Authority
AT
Austria
Prior art keywords
phosphorylation
protein
proteins
quantifying
tau
Prior art date
Application number
AT01973567T
Other languages
English (en)
Inventor
Kevin Reagan
Erik Schaeffer
Jimin Wang
Original Assignee
Invitrogen Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Invitrogen Corp filed Critical Invitrogen Corp
Application granted granted Critical
Publication of ATE416385T1 publication Critical patent/ATE416385T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4709—Amyloid plaque core protein

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT01973567T 2000-09-27 2001-09-27 Verfahren zur quantifizierung der phosphokinaseaktivität auf proteinen ATE416385T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US23562000P 2000-09-27 2000-09-27

Publications (1)

Publication Number Publication Date
ATE416385T1 true ATE416385T1 (de) 2008-12-15

Family

ID=22886277

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01973567T ATE416385T1 (de) 2000-09-27 2001-09-27 Verfahren zur quantifizierung der phosphokinaseaktivität auf proteinen

Country Status (7)

Country Link
US (4) US20030162230A1 (de)
EP (3) EP2040078A1 (de)
JP (2) JP2004516823A (de)
AT (1) ATE416385T1 (de)
CA (1) CA2423979C (de)
DE (1) DE60136840D1 (de)
WO (1) WO2002027017A2 (de)

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US7807789B2 (en) * 2004-12-21 2010-10-05 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in EGFR-signaling pathways
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WO2007133688A2 (en) * 2006-05-12 2007-11-22 Cell Signaling Technology, Inc. Reagents for the detection of tyrosine phosphorylation in brain ischemia signaling pathways
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US20130231305A1 (en) * 2010-03-29 2013-09-05 Medvet Science Pty. Ltd. Method of Modulating Protein 14-3-3 Functionality By Facilitating or Inhibiting Phosphorylation
US20170016900A1 (en) 2010-09-07 2017-01-19 Stephen G. Marx Kit for monitoring, detecting and staging gvhd
WO2012032511A2 (en) * 2010-09-07 2012-03-15 Stephen G Marx Kit for monitoring, detecting and staging gvhd
US9200068B2 (en) 2012-12-18 2015-12-01 Regents Of The University Of Minnesota Compositions and methods related to tauopathy
AU2014368696A1 (en) 2013-12-20 2016-06-02 F. Hoffmann-La Roche Ag Humanized anti-Tau(pS422) antibodies and methods of use
JP6584322B2 (ja) * 2013-12-27 2019-10-02 国立大学法人 東京医科歯科大学 アルツハイマー病及び前頭側頭葉変性症の診断方法、診断薬、治療薬、及びこれら薬剤のスクリーニング方法
JP6840541B2 (ja) * 2014-03-31 2021-03-10 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ 修飾特異的バインダーを使用することによる分析物を分析するための方法
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CN113929779B (zh) 2015-06-24 2025-02-25 豪夫迈·罗氏有限公司 人源化的抗-Tau(pS422)抗体和使用方法
JO3711B1 (ar) 2015-07-13 2021-01-31 H Lundbeck As أجسام مضادة محددة لبروتين تاو وطرق استعمالها
US20190388519A1 (en) * 2016-03-01 2019-12-26 Macquarie University Use of phosphorylated tau and p38gamma to treat a neurological condition
NZ748983A (en) 2016-07-12 2022-12-23 H Lundbeck As Antibodies specific for hyperphosphorylated tau and methods of use thereof
EP3324187B1 (de) * 2016-11-21 2020-03-11 Ruhr-Universität Bochum Kombinations-assay für die differenzialdiagnose der alzheimer-krankheit
JP7217710B2 (ja) 2017-01-04 2023-02-03 ハー・ルンドベック・アクチエゼルスカベット 眼疾患の治療のための過リン酸化タウに特異的な抗体
KR20200100726A (ko) * 2017-12-18 2020-08-26 예일 유니버시티 섬유증 치료용 화합물 및 조성물
AU2019232631A1 (en) 2018-03-05 2020-09-24 Janssen Pharmaceutica Nv Anti-PHF-tau antibodies and uses thereof
MX2020009278A (es) 2018-03-05 2021-01-08 Janssen Pharmaceutica Nv Ensayos para detectar la neurodegeneración.
US11085935B2 (en) * 2018-05-03 2021-08-10 Washington University Methods of treating based on site-specific tau phosphorylation
US12331320B2 (en) 2018-10-10 2025-06-17 The Research Foundation For The State University Of New York Genome edited cancer cell vaccines
MX2022002880A (es) 2019-09-10 2022-03-25 Washington University St Louis Ensayo basado en sangre para diagnosticar y tratar fosforilacion de tau especifica con base en el sitio.

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Also Published As

Publication number Publication date
US20090104628A1 (en) 2009-04-23
US7888050B2 (en) 2011-02-15
US20120135426A1 (en) 2012-05-31
CA2423979A1 (en) 2002-04-04
US8114617B2 (en) 2012-02-14
EP1328812B1 (de) 2008-12-03
WO2002027017A3 (en) 2003-01-16
EP2298814A2 (de) 2011-03-23
EP1328812A2 (de) 2003-07-23
DE60136840D1 (de) 2009-01-15
US20030162230A1 (en) 2003-08-28
EP2298814A3 (de) 2012-05-30
WO2002027017A2 (en) 2002-04-04
US20110165588A1 (en) 2011-07-07
CA2423979C (en) 2012-03-06
JP2004516823A (ja) 2004-06-10
JP2006225396A (ja) 2006-08-31
EP2040078A1 (de) 2009-03-25

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