ATE488588T1 - Verfahren zur kennzeichnung mesenchymaler stammzellen unter verwendung verschiedener marker - Google Patents
Verfahren zur kennzeichnung mesenchymaler stammzellen unter verwendung verschiedener markerInfo
- Publication number
- ATE488588T1 ATE488588T1 AT07017847T AT07017847T ATE488588T1 AT E488588 T1 ATE488588 T1 AT E488588T1 AT 07017847 T AT07017847 T AT 07017847T AT 07017847 T AT07017847 T AT 07017847T AT E488588 T1 ATE488588 T1 AT E488588T1
- Authority
- AT
- Austria
- Prior art keywords
- mesenchymal stem
- marker
- detecting
- stem cell
- gene
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Plant Pathology (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003063077 | 2003-03-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE488588T1 true ATE488588T1 (de) | 2010-12-15 |
Family
ID=32984419
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07017847T ATE488588T1 (de) | 2003-03-10 | 2004-02-27 | Verfahren zur kennzeichnung mesenchymaler stammzellen unter verwendung verschiedener marker |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20060166214A1 (de) |
| EP (2) | EP1605044A4 (de) |
| JP (1) | JP2004290189A (de) |
| KR (1) | KR100818689B1 (de) |
| CN (2) | CN1761749A (de) |
| AT (1) | ATE488588T1 (de) |
| AU (1) | AU2004219820B2 (de) |
| DE (1) | DE602004030172D1 (de) |
| WO (1) | WO2004081174A2 (de) |
Families Citing this family (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1870455A4 (de) * | 2005-03-31 | 2010-01-20 | Two Cells Co Ltd | Verfahren zur unterscheidung einer mesenchym-stammzelle unter verwendung eines molekularen markers und verwendung davon |
| EP1878789A4 (de) * | 2005-04-14 | 2008-08-27 | Japan As Represented By Genera | Aus fett stammende vorläuferzelle und verwendung davon |
| US20060246498A1 (en) * | 2005-04-28 | 2006-11-02 | Ramot At Tel Aviv University Ltd. | HNRPLL polypeptides, polynucleotides encoding same and compositions and methods of using same |
| JP4958094B2 (ja) * | 2005-09-22 | 2012-06-20 | 国立大学法人広島大学 | 間葉系幹細胞の均質性識別方法、その方法を利用して得られる均質間葉系幹細胞 |
| EA017812B1 (ru) | 2005-12-08 | 2013-03-29 | Медарекс, Инк. | Выделенное моноклональное антитело или его антигенсвязывающий участок, которые связываются с протеинтирозинкиназой 7 ( ptk7) человека, и их применение |
| US20090061478A1 (en) * | 2006-01-30 | 2009-03-05 | Lene Have Poulsen | High-Speed Quantification of Antigen Specific T-Cells in Whole Blood by Flow Cytometry |
| JP2008092919A (ja) * | 2006-10-16 | 2008-04-24 | Hiroshima Univ | 病変間葉系幹細胞の検出マーカーの利用 |
| AU2008210421B2 (en) * | 2007-01-30 | 2014-03-13 | Pharmacyclics Llc | Methods for determining cancer resistance to histone deacetylase inhibitors |
| WO2008116468A2 (en) | 2007-03-26 | 2008-10-02 | Dako Denmark A/S | Mhc peptide complexes and uses thereof in infectious diseases |
| KR100888924B1 (ko) | 2007-06-04 | 2009-03-16 | 주식회사 제이비줄기세포연구소 | 인간 제대혈 유래 중간엽 줄기세포와 섬유아세포 분별방법 |
| EP3620465B1 (de) | 2007-07-03 | 2025-02-19 | Dako Denmark A/S | Verbesserte verfahren zur herstellung, markierung und verwendung von mhc-multimeren |
| US10611818B2 (en) | 2007-09-27 | 2020-04-07 | Agilent Technologies, Inc. | MHC multimers in tuberculosis diagnostics, vaccine and therapeutics |
| WO2009076638A2 (en) * | 2007-12-13 | 2009-06-18 | Robert Bradbury | Compositions and methods relating to characterization and therapeutic application of pristine stem cells |
| DK2254592T3 (da) | 2008-02-28 | 2019-09-09 | Dako Denmark As | MHC-multimerer til Borrelia-diagnostik og sygdom |
| WO2010009735A2 (en) * | 2008-07-23 | 2010-01-28 | Dako Denmark A/S | Combinatorial analysis and repair |
| GB0817244D0 (en) * | 2008-09-20 | 2008-10-29 | Univ Cardiff | Use of a protein kinase inhibitor to detect immune cells, such as T cells |
| WO2010037402A1 (en) | 2008-10-02 | 2010-04-08 | Dako Denmark A/S | Molecular vaccines for infectious disease |
| US11992518B2 (en) | 2008-10-02 | 2024-05-28 | Agilent Technologies, Inc. | Molecular vaccines for infectious disease |
| JP2010189302A (ja) * | 2009-02-17 | 2010-09-02 | Hiroshima Univ | 病変間葉系幹細胞が関連する疾患の治療剤および間葉系幹細胞の検出マーカーの利用 |
| JP5602850B2 (ja) * | 2009-07-14 | 2014-10-08 | ザ スクリプス リサーチ インスティテュート | 間葉幹細胞分化 |
| WO2012048276A2 (en) | 2010-10-08 | 2012-04-12 | Caridianbct, Inc. | Customizable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system |
| ES2384790B1 (es) * | 2010-12-10 | 2013-05-20 | Instituto De Salud Carlos Iii | Células madre mesenquimales aisladas a partir de sangre periférica. |
| EP2687847B1 (de) | 2011-03-16 | 2019-03-06 | Tohoku University | Sonde zum analysieren biologischer gewebe und verfahren zu ihrer anwendung |
| KR101374247B1 (ko) | 2011-09-23 | 2014-03-13 | 가톨릭대학교기술지주 주식회사 | 고해상도 mica 대립유전자 검출용 sprex―dna 칩 키트 |
| ES2700980T3 (es) * | 2012-02-17 | 2019-02-20 | Schepens Eye Res Inst | Perfil fenotípico de células progenitoras de retina humana |
| EP2841564B1 (de) * | 2012-04-24 | 2018-03-07 | Stemlab, S.A. | Stammzellenzusammensetzung und verfahren zur erhaltung von herzgewebe |
| CN102732633B (zh) * | 2012-07-06 | 2014-02-26 | 广州好芝生物科技有限公司 | 人idh基因突变的检测引物和试剂盒 |
| CN102925579B (zh) * | 2012-11-16 | 2014-12-17 | 上海赛安医学检验所有限公司 | Idh2基因突变的快速检测方法 |
| CN105008519A (zh) | 2013-02-01 | 2015-10-28 | 国立大学法人东北大学 | 从生物组织分离细胞的方法 |
| GB201310354D0 (en) * | 2013-06-11 | 2013-07-24 | Ge Healthcare Uk Ltd | Method for cell differentiation |
| WO2015073913A1 (en) | 2013-11-16 | 2015-05-21 | Terumo Bct, Inc. | Expanding cells in a bioreactor |
| JP6339814B2 (ja) * | 2014-02-05 | 2018-06-06 | 株式会社島津製作所 | がん転移マーカー及びその分析方法 |
| WO2015148704A1 (en) | 2014-03-25 | 2015-10-01 | Terumo Bct, Inc. | Passive replacement of media |
| EP3198006B1 (de) | 2014-09-26 | 2021-03-24 | Terumo BCT, Inc. | Geplante fütterung |
| KR102045130B1 (ko) * | 2014-12-05 | 2019-11-14 | 메리디젠 바이오테크 컴퍼니 리미티드 | 중간엽 줄기세포를 구별하는 방법 |
| CN104844705B (zh) * | 2015-01-30 | 2018-08-03 | 暨南大学 | Kctd12蛋白在细胞周期调控中的应用 |
| CN104655857B (zh) * | 2015-02-10 | 2017-05-31 | 南京大学 | 一种微生物细胞内多聚磷酸盐的定量检测方法 |
| CN108064342A (zh) * | 2015-03-17 | 2018-05-22 | 国立研究开发法人产业技术综合研究所 | 用于检测干细胞的方法及试剂盒 |
| WO2017004592A1 (en) | 2015-07-02 | 2017-01-05 | Terumo Bct, Inc. | Cell growth with mechanical stimuli |
| CN105018524B (zh) * | 2015-07-13 | 2020-03-27 | 广州赛琅生物技术有限公司 | 一种细胞寿命延长及成血管能力增强的人干细胞的制备方法及其试剂盒 |
| US11965175B2 (en) | 2016-05-25 | 2024-04-23 | Terumo Bct, Inc. | Cell expansion |
| US11104874B2 (en) | 2016-06-07 | 2021-08-31 | Terumo Bct, Inc. | Coating a bioreactor |
| US11685883B2 (en) | 2016-06-07 | 2023-06-27 | Terumo Bct, Inc. | Methods and systems for coating a cell growth surface |
| CN106771256B (zh) * | 2017-01-23 | 2019-02-01 | 福建医科大学 | 骨骼肌组织冰冻切片肌球蛋白三磷酸腺苷酶染色方法 |
| CN116590227A (zh) * | 2017-03-03 | 2023-08-15 | 日本乐敦制药株式会社 | 间充质干细胞和肝疾病治疗剂 |
| CN117247899A (zh) | 2017-03-31 | 2023-12-19 | 泰尔茂比司特公司 | 细胞扩增 |
| US11624046B2 (en) | 2017-03-31 | 2023-04-11 | Terumo Bct, Inc. | Cell expansion |
| US12234441B2 (en) | 2017-03-31 | 2025-02-25 | Terumo Bct, Inc. | Cell expansion |
| BR112019020959A2 (pt) * | 2017-04-10 | 2020-05-05 | Immatics Biotechnologies Gmbh | peptídeos e combinações dos mesmos para uso na imunoterapia contra câncer |
| WO2020127222A2 (en) | 2018-12-17 | 2020-06-25 | Immudex Aps | Panel comprising borrelia mhc multimers |
| PL241520B1 (pl) * | 2020-03-27 | 2022-10-17 | Polski Bank Komorek Macierzystych Spolka Akcyjna | Zastosowanie panelu genów do określania potencjału teratogennego komórek mezenchymalnych i pochodzenia perinatalnego |
| US20240018588A1 (en) * | 2020-12-07 | 2024-01-18 | Samsung Life Public Welfare Foundation | Method for selecting mesenchymal stem cells having improved self-maintenance ability, and mesenchymal stem cells selected thereby |
| EP4314244B1 (de) | 2021-03-23 | 2025-07-23 | Terumo BCT, Inc. | Zellerfassung und -erweiterung |
| EP4408979A1 (de) * | 2021-09-30 | 2024-08-07 | Polski Bank Komórek Macierzystych S.A. | Expressionsanalyse eines spezifischen genpools zur bestimmung der population fettgewebe-derivierter mesenchymzellen |
| US12209689B2 (en) | 2022-02-28 | 2025-01-28 | Terumo Kabushiki Kaisha | Multiple-tube pinch valve assembly |
| CN114622019A (zh) * | 2022-03-23 | 2022-06-14 | 新乡医学院 | Birc5基因作为人骨髓间充质干细胞成骨分化抑制剂的应用 |
| USD1099116S1 (en) | 2022-09-01 | 2025-10-21 | Terumo Bct, Inc. | Display screen or portion thereof with a graphical user interface for displaying cell culture process steps and measurements of an associated bioreactor device |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5340739A (en) * | 1988-07-13 | 1994-08-23 | Brigham & Women's Hospital | Hematopoietic cell specific transcriptional regulatory elements of serglycin and uses thereof |
| CA2271758A1 (en) * | 1996-11-15 | 1998-05-22 | Osiris Therapeutics, Inc. | Msc-megakaryocyte precursor composition and method of isolating mscs associated with isolated megakaryocytes by isolating megakaryocytes |
| AU2180799A (en) * | 1998-02-13 | 1999-08-30 | Peter Sonderegger | Neuroserpin |
| DE60120151D1 (de) * | 2000-04-28 | 2006-07-06 | Childrens Medical Center | Isolierung von mesenchymalen stammzellen und deren verwendung |
| CA2411601A1 (en) * | 2000-06-05 | 2001-12-13 | Avalon Pharmaceuticals | Cancer gene determination and therapeutic screening using signature gene sets |
| AU2126502A (en) * | 2000-10-03 | 2002-04-15 | Gene Logic, Inc. | Gene expression profiles in granulocytic cells |
| JP2003052365A (ja) * | 2001-08-20 | 2003-02-25 | Japan Science & Technology Corp | 哺乳動物からの間葉系幹細胞の分離及びその利用方法 |
| EP1288293A1 (de) * | 2001-08-30 | 2003-03-05 | Norio Sakuragawa | Humane neuronale Stammzellen aus humanen mesenchymalen Amnionzellschichten |
-
2004
- 2004-02-27 DE DE602004030172T patent/DE602004030172D1/de not_active Expired - Lifetime
- 2004-02-27 EP EP04715524A patent/EP1605044A4/de not_active Withdrawn
- 2004-02-27 EP EP07017847A patent/EP1860186B1/de not_active Expired - Lifetime
- 2004-02-27 WO PCT/JP2004/002457 patent/WO2004081174A2/ja not_active Ceased
- 2004-02-27 CN CNA2004800075500A patent/CN1761749A/zh active Pending
- 2004-02-27 KR KR1020057016952A patent/KR100818689B1/ko not_active Expired - Fee Related
- 2004-02-27 AT AT07017847T patent/ATE488588T1/de not_active IP Right Cessation
- 2004-02-27 US US10/548,681 patent/US20060166214A1/en not_active Abandoned
- 2004-02-27 AU AU2004219820A patent/AU2004219820B2/en not_active Ceased
- 2004-02-27 CN CNA200810081304XA patent/CN101265503A/zh active Pending
- 2004-03-10 JP JP2004067037A patent/JP2004290189A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR20050115278A (ko) | 2005-12-07 |
| EP1605044A4 (de) | 2006-12-06 |
| CN101265503A (zh) | 2008-09-17 |
| CN1761749A (zh) | 2006-04-19 |
| EP1860186A2 (de) | 2007-11-28 |
| KR100818689B1 (ko) | 2008-04-02 |
| AU2004219820A1 (en) | 2004-09-23 |
| WO2004081174A3 (ja) | 2004-12-02 |
| EP1860186A3 (de) | 2008-03-12 |
| US20060166214A1 (en) | 2006-07-27 |
| WO2004081174A2 (ja) | 2004-09-23 |
| EP1605044A2 (de) | 2005-12-14 |
| EP1860186B1 (de) | 2010-11-17 |
| JP2004290189A (ja) | 2004-10-21 |
| DE602004030172D1 (de) | 2010-12-30 |
| AU2004219820B2 (en) | 2008-06-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |