ATE417857T1 - Quaternäre terpensalze als biologisch aktive tenside - Google Patents

Quaternäre terpensalze als biologisch aktive tenside

Info

Publication number
ATE417857T1
ATE417857T1 AT03703915T AT03703915T ATE417857T1 AT E417857 T1 ATE417857 T1 AT E417857T1 AT 03703915 T AT03703915 T AT 03703915T AT 03703915 T AT03703915 T AT 03703915T AT E417857 T1 ATE417857 T1 AT E417857T1
Authority
AT
Austria
Prior art keywords
quaternary
terpene
salts
biologically active
active surfactants
Prior art date
Application number
AT03703915T
Other languages
English (en)
Inventor
Pavel Krasutsky
Dmytro Avilov
Tatiana Sergeeva
Dmytro Krasutsky
Oksana Kolomitsyna
Original Assignee
Univ Minnesota
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Minnesota filed Critical Univ Minnesota
Application granted granted Critical
Publication of ATE417857T1 publication Critical patent/ATE417857T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT03703915T 2002-01-18 2003-01-21 Quaternäre terpensalze als biologisch aktive tenside ATE417857T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US34956402P 2002-01-18 2002-01-18

Publications (1)

Publication Number Publication Date
ATE417857T1 true ATE417857T1 (de) 2009-01-15

Family

ID=27613290

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03703915T ATE417857T1 (de) 2002-01-18 2003-01-21 Quaternäre terpensalze als biologisch aktive tenside

Country Status (10)

Country Link
US (5) US7199114B2 (de)
EP (1) EP1465914B1 (de)
JP (1) JP2005519913A (de)
AT (1) ATE417857T1 (de)
AU (1) AU2003205244B2 (de)
CA (1) CA2473799A1 (de)
DE (1) DE60325329D1 (de)
IL (1) IL163077A (de)
MX (1) MXPA04006953A (de)
WO (1) WO2003062260A1 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA04006953A (es) * 2002-01-18 2005-06-20 Univ Minnesota Sales cuaternarias de triperpeno como surfactantes biologicamente activos.
US20090131714A1 (en) * 2005-06-08 2009-05-21 Krasutsky Pavel A Synthesis of betulonic and betulinic aldehydes
FI121468B (fi) * 2006-06-07 2010-11-30 Valtion Teknillinen Betuliiniperäiset yhdisteet antimikrobisina aineina
JP2008123753A (ja) * 2006-11-09 2008-05-29 Koito Mfg Co Ltd 車両用灯具ユニット
WO2009073818A1 (en) * 2007-12-04 2009-06-11 Myriad Genetics, Inc. Compounds and therapeutic use thereof
HUE043175T2 (hu) 2008-01-11 2019-08-28 Reata Pharmaceuticals Inc Szintetikus triterpenoidok és alkalmazásuk betegség kezelésében
WO2009090063A1 (en) * 2008-01-16 2009-07-23 Jado Technologies Gmbh Steroid sapogenin, androstane and triterpenoid sapogenin derivatives for the treatment and prevention of infectious diseases
MX339476B (es) 2008-04-18 2016-05-27 Reata Pharmaceuticals Inc Compuestos que incluyen un nucleo farmaceutico antiinflamatorio y sus metodos de uso.
KR101713140B1 (ko) 2008-04-18 2017-03-08 리타 파마슈티컬스 잉크. Ｃ-환에서 포화된 산화방지성 염증 조절제 올레아놀산 유도체
CN104250280A (zh) 2008-04-18 2014-12-31 里亚塔医药公司 抗氧化剂炎症调节剂:c-17同系化齐墩果酸衍生物
ES2703274T3 (es) 2008-04-18 2019-03-07 Reata Pharmaceuticals Inc Moduladores de la inflamación antioxidantes: derivados del ácido oleanólico con modificaciones amino y otras en C-17
PT104607B (pt) * 2009-05-20 2012-03-23 Univ De Coimbra Derivados triterpenóides úteis como agentes antiproliferativos
HRP20171859T1 (hr) 2010-12-17 2018-01-26 Reata Pharmaceuticals, Inc. Pirazolil i pirimidinil triciklički enoni kao antioksidacijski modulatori upale
CA2829618C (en) 2011-03-11 2019-07-09 Reata Pharmaceuticals, Inc. C4-monomethyl triterpenoid derivatives and methods of use thereof
DK3444261T3 (da) 2012-04-27 2021-03-08 Reata Pharmaceuticals Inc 2,2-difluorpropionamidderivat af bardoxolonmethyl, farmaceutiske sammensætninger og polymorfer deraf til anvendelse ved behandling af visse lidelser
US9556222B2 (en) 2012-06-15 2017-01-31 Reata Pharmaceuticals, Inc. A-ring epoxidized triterpenoid-based anti-inflammation modulators and methods of use thereof
US9512094B2 (en) 2012-09-10 2016-12-06 Reata Pharmaceuticals, Inc. C17-heteroaryl derivatives of oleanolic acid and methods of use thereof
PL2892912T3 (pl) 2012-09-10 2019-10-31 Reata Pharmaceuticals Inc C17-alkanodiylowe i alkenodiylowe pochodne kwasu oleanolowego i sposoby ich zastosowania
US9278912B2 (en) 2012-09-10 2016-03-08 Reata Pharmaceuticals, Inc. C13-hydroxy derivatives of oleanolic acid and methods of use thereof
TWI649330B (zh) 2013-04-24 2019-02-01 艾伯維有限公司 甲基巴多索龍之２，２－二氟丙醯胺衍生物、其多晶形及其使用方法
CN104387440A (zh) * 2014-11-07 2015-03-04 上海应用技术学院 一种白桦脂醇氨基酸酯化合物及其制备方法和用途
EA201890767A1 (ru) 2015-09-23 2019-09-30 Рита Фармасьютикалз, Инк. C4-модифицированные производные олеаноловой кислоты для ингибирования il-17 и других применений
US11547666B2 (en) * 2018-05-30 2023-01-10 Translate Bio, Inc. Cationic lipids comprising a steroidal moiety
EP3810141A1 (de) 2018-06-20 2021-04-28 Reata Pharmaceuticals, Inc. Cysteinabhängige inverse agonisten von kernrezeptoren-ror-gamma/ror-gamma-t und verfahren zur behandlung von erkrankungen oder störungen damit
RU2725873C2 (ru) * 2018-08-20 2020-07-07 Федеральное государственное бюджетное научное учреждение Уфимский федеральный исследовательский центр Российской академии наук Способ получения 1-(3-гидрокси, 28-ацетоксилуп-20(29)-ен-30-ил)-пиридиний бромида и его применение в качестве средства с антибактериальной и противогрибковой активностью
KR102891865B1 (ko) 2019-07-19 2025-11-26 리아타 파마슈티컬즈, 아이엔씨. C17 극성-치환된 헤테로방향족 합성 트리터페노이드 및 그의 사용 방법
CN113876595A (zh) * 2021-10-18 2022-01-04 东华大学 桦木醇基季铵盐类抗菌型有机单体及其复合树脂的用途和其复合树脂的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1454749A (en) * 1972-11-29 1976-11-03 Akzo Nv 2beta, 16beta-diamino-androstanes and their preparation
ES423577A1 (es) * 1974-02-23 1976-05-16 Landerlan S A Procedimiento de obtencion de derivados de acidos triterpe-nicos.
CH602794A5 (de) * 1974-10-29 1978-08-15 Hoffmann La Roche
KR910008736B1 (ko) * 1989-06-13 1991-10-19 태평양화학주식회사 4급암모니움-치환된 사포닌 에테르 유도체 및 그 제조방법
US6303589B1 (en) 1998-12-08 2001-10-16 Micro Flo Company Pentacyclic triterpenes
MXPA04006953A (es) * 2002-01-18 2005-06-20 Univ Minnesota Sales cuaternarias de triperpeno como surfactantes biologicamente activos.

Also Published As

Publication number Publication date
AU2003205244B2 (en) 2009-01-08
US7410958B2 (en) 2008-08-12
US20050059642A1 (en) 2005-03-17
CA2473799A1 (en) 2003-07-31
EP1465914A1 (de) 2004-10-13
IL163077A (en) 2009-06-15
MXPA04006953A (es) 2005-06-20
US20070088009A1 (en) 2007-04-19
EP1465914B1 (de) 2008-12-17
US20070244081A1 (en) 2007-10-18
JP2005519913A (ja) 2005-07-07
US7199114B2 (en) 2007-04-03
US20070259842A1 (en) 2007-11-08
DE60325329D1 (de) 2009-01-29
WO2003062260A1 (en) 2003-07-31
US20070259839A1 (en) 2007-11-08

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