ATE417857T1 - Quaternäre terpensalze als biologisch aktive tenside - Google Patents

Quaternäre terpensalze als biologisch aktive tenside

Info

Publication number
ATE417857T1
ATE417857T1 AT03703915T AT03703915T ATE417857T1 AT E417857 T1 ATE417857 T1 AT E417857T1 AT 03703915 T AT03703915 T AT 03703915T AT 03703915 T AT03703915 T AT 03703915T AT E417857 T1 ATE417857 T1 AT E417857T1
Authority
AT
Austria
Prior art keywords
quaternary
terpene
salts
biologically active
active surfactants
Prior art date
Application number
AT03703915T
Other languages
English (en)
Inventor
Pavel Krasutsky
Dmytro Avilov
Tatiana Sergeeva
Dmytro Krasutsky
Oksana Kolomitsyna
Original Assignee
Univ Minnesota
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Minnesota filed Critical Univ Minnesota
Application granted granted Critical
Publication of ATE417857T1 publication Critical patent/ATE417857T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT03703915T 2002-01-18 2003-01-21 Quaternäre terpensalze als biologisch aktive tenside ATE417857T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US34956402P 2002-01-18 2002-01-18

Publications (1)

Publication Number Publication Date
ATE417857T1 true ATE417857T1 (de) 2009-01-15

Family

ID=27613290

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03703915T ATE417857T1 (de) 2002-01-18 2003-01-21 Quaternäre terpensalze als biologisch aktive tenside

Country Status (10)

Country Link
US (5) US7199114B2 (de)
EP (1) EP1465914B1 (de)
JP (1) JP2005519913A (de)
AT (1) ATE417857T1 (de)
AU (1) AU2003205244B2 (de)
CA (1) CA2473799A1 (de)
DE (1) DE60325329D1 (de)
IL (1) IL163077A (de)
MX (1) MXPA04006953A (de)
WO (1) WO2003062260A1 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003205244B2 (en) * 2002-01-18 2009-01-08 Regents Of The University Of Minnesota Triterpene quaternary salts as biologically active surfactants
US20090131714A1 (en) * 2005-06-08 2009-05-21 Krasutsky Pavel A Synthesis of betulonic and betulinic aldehydes
FI121468B (fi) * 2006-06-07 2010-11-30 Valtion Teknillinen Betuliiniperäiset yhdisteet antimikrobisina aineina
JP2008123753A (ja) * 2006-11-09 2008-05-29 Koito Mfg Co Ltd 車両用灯具ユニット
EP2231163A4 (de) * 2007-12-04 2012-10-31 Myriad Pharmaceuticals Inc Verbindungen und ihre therapeutische anwendung
TWI492745B (zh) 2008-01-11 2015-07-21 Reata Pharmaceuticals Inc 合成的三萜系化合物及其使用於治療疾病之方法
WO2009090063A1 (en) * 2008-01-16 2009-07-23 Jado Technologies Gmbh Steroid sapogenin, androstane and triterpenoid sapogenin derivatives for the treatment and prevention of infectious diseases
EA022588B1 (ru) 2008-04-18 2016-01-29 Ритэ Фамэсутикл, Инк. Антиоксидантные модуляторы воспаления: производные олеанолевой кислоты с насыщением в с-кольце
DK2276493T3 (da) 2008-04-18 2019-01-02 Reata Pharmaceuticals Inc Antioxidative inflammationsmodulatorer: oleanolsyrederivater med amino- og andre modifikationer ved c-17
WO2009129548A1 (en) 2008-04-18 2009-10-22 Reata Pharmaceuticals, Inc. Antioxidant inflammation modulators: c-17 homologated oleanolic acid derivatives
MX2010011435A (es) 2008-04-18 2011-01-25 Reata Pharmaceuticals Inc Compuestos que incluyen un nucleo farmaceutico antiinflamatorio y sus metodos de uso.
PT104607B (pt) * 2009-05-20 2012-03-23 Univ De Coimbra Derivados triterpenóides úteis como agentes antiproliferativos
NZ612788A (en) 2010-12-17 2015-10-30 Reata Pharmaceuticals Inc Pyrazolyl and pyrimidinyl tricyclic enones as antioxidant inflammation modulators
EP2683731B1 (de) 2011-03-11 2019-04-24 Reata Pharmaceuticals, Inc. C4-monomethyl-triterpenoidderivate und verwendungsverfahren dafür
SI3444261T1 (sl) 2012-04-27 2021-04-30 Reata Pharmaceuticals, Inc. 2,2-difluoropropionamidni derivat bardoksolon metila, njegovi farmacevtski sestavki in polimorfi za uporabo pri zdravljenju določenih stanj
WO2013188818A1 (en) 2012-06-15 2013-12-19 Reata Pharmaceuticals, Inc. A-ring epoxidized triterpenoid-based anti-inflammation modulators and methods of use thereof
US9278912B2 (en) 2012-09-10 2016-03-08 Reata Pharmaceuticals, Inc. C13-hydroxy derivatives of oleanolic acid and methods of use thereof
PL2892912T3 (pl) 2012-09-10 2019-10-31 Reata Pharmaceuticals Inc C17-alkanodiylowe i alkenodiylowe pochodne kwasu oleanolowego i sposoby ich zastosowania
US9512094B2 (en) 2012-09-10 2016-12-06 Reata Pharmaceuticals, Inc. C17-heteroaryl derivatives of oleanolic acid and methods of use thereof
UY35534A (es) 2013-04-24 2014-10-31 Abbvie Inc Derivados de 2,2-difluoropropanamida y metil bardoxolona, formas polimórficas y métodos de uso
CN104387440A (zh) * 2014-11-07 2015-03-04 上海应用技术学院 一种白桦脂醇氨基酸酯化合物及其制备方法和用途
MX386256B (es) 2015-09-23 2025-03-18 Reata Pharmaceuticals Inc Derivados de acido oleanolico modificado en c4 para la inhibicion de il-17 y otros usos.
CA3100214A1 (en) * 2018-05-30 2019-12-05 Translate Bio, Inc. Cationic lipids comprising a steroidal moiety
US12060340B2 (en) 2018-06-20 2024-08-13 Reata Pharmaceuticals, Inc Cysteine-dependent inverse agonists of nuclear receptors ROR-gamma/ROR-gamma-t and methods of treating diseases or disorders therewith
RU2725873C2 (ru) * 2018-08-20 2020-07-07 Федеральное государственное бюджетное научное учреждение Уфимский федеральный исследовательский центр Российской академии наук Способ получения 1-(3-гидрокси, 28-ацетоксилуп-20(29)-ен-30-ил)-пиридиний бромида и его применение в качестве средства с антибактериальной и противогрибковой активностью
WO2021016191A1 (en) 2019-07-19 2021-01-28 Reata Pharmaceuticals, Inc. C17 polar-substituted heteroaromatic synthetic triterpenoids and methods of use thereof
CN113876595A (zh) * 2021-10-18 2022-01-04 东华大学 桦木醇基季铵盐类抗菌型有机单体及其复合树脂的用途和其复合树脂的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1454749A (en) * 1972-11-29 1976-11-03 Akzo Nv 2beta, 16beta-diamino-androstanes and their preparation
ES423577A1 (es) * 1974-02-23 1976-05-16 Landerlan S A Procedimiento de obtencion de derivados de acidos triterpe-nicos.
CH602794A5 (de) * 1974-10-29 1978-08-15 Hoffmann La Roche
KR910008736B1 (ko) * 1989-06-13 1991-10-19 태평양화학주식회사 4급암모니움-치환된 사포닌 에테르 유도체 및 그 제조방법
US6303589B1 (en) 1998-12-08 2001-10-16 Micro Flo Company Pentacyclic triterpenes
AU2003205244B2 (en) 2002-01-18 2009-01-08 Regents Of The University Of Minnesota Triterpene quaternary salts as biologically active surfactants

Also Published As

Publication number Publication date
US7199114B2 (en) 2007-04-03
DE60325329D1 (de) 2009-01-29
AU2003205244B2 (en) 2009-01-08
CA2473799A1 (en) 2003-07-31
EP1465914A1 (de) 2004-10-13
MXPA04006953A (es) 2005-06-20
US20070244081A1 (en) 2007-10-18
US20070088009A1 (en) 2007-04-19
JP2005519913A (ja) 2005-07-07
US20050059642A1 (en) 2005-03-17
US7410958B2 (en) 2008-08-12
US20070259842A1 (en) 2007-11-08
WO2003062260A1 (en) 2003-07-31
EP1465914B1 (de) 2008-12-17
US20070259839A1 (en) 2007-11-08
IL163077A (en) 2009-06-15

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