ATE418327T1 - Pharmazeutische granulatzusammensetzungen mit sofortiger freisetzung und kontinuierliches verfahren zu ihrer herstellung - Google Patents

Pharmazeutische granulatzusammensetzungen mit sofortiger freisetzung und kontinuierliches verfahren zu ihrer herstellung

Info

Publication number
ATE418327T1
ATE418327T1 AT03743276T AT03743276T ATE418327T1 AT E418327 T1 ATE418327 T1 AT E418327T1 AT 03743276 T AT03743276 T AT 03743276T AT 03743276 T AT03743276 T AT 03743276T AT E418327 T1 ATE418327 T1 AT E418327T1
Authority
AT
Austria
Prior art keywords
production
continuous process
immediate release
release pharmaceutical
granular compositions
Prior art date
Application number
AT03743276T
Other languages
English (en)
Inventor
Jean-Paul Remon
Kris Vervaet
Original Assignee
Univ Gent
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Gent filed Critical Univ Gent
Application granted granted Critical
Publication of ATE418327T1 publication Critical patent/ATE418327T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT03743276T 2002-03-06 2003-03-05 Pharmazeutische granulatzusammensetzungen mit sofortiger freisetzung und kontinuierliches verfahren zu ihrer herstellung ATE418327T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0205253.8A GB0205253D0 (en) 2002-03-06 2002-03-06 Immediate release pharmaceutical granule compositions and a continuous process for making them

Publications (1)

Publication Number Publication Date
ATE418327T1 true ATE418327T1 (de) 2009-01-15

Family

ID=9932403

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03743276T ATE418327T1 (de) 2002-03-06 2003-03-05 Pharmazeutische granulatzusammensetzungen mit sofortiger freisetzung und kontinuierliches verfahren zu ihrer herstellung

Country Status (21)

Country Link
US (4) US20050058705A1 (de)
EP (1) EP1480622B1 (de)
KR (1) KR20040091099A (de)
CN (1) CN1638738B (de)
AR (1) AR038880A1 (de)
AT (1) ATE418327T1 (de)
AU (1) AU2003215449B2 (de)
BR (1) BR0308231A (de)
CA (1) CA2477890C (de)
DE (1) DE60325461D1 (de)
DK (1) DK1480622T3 (de)
ES (1) ES2318147T3 (de)
GB (1) GB0205253D0 (de)
MX (1) MXPA04008543A (de)
MY (1) MY138752A (de)
PL (1) PL208133B1 (de)
PT (1) PT1480622E (de)
SA (1) SA03240089B1 (de)
TW (1) TWI296198B (de)
WO (1) WO2003074031A1 (de)
ZA (1) ZA200407998B (de)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0205253D0 (en) 2002-03-06 2002-04-17 Univ Gent Immediate release pharmaceutical granule compositions and a continuous process for making them
AU2004238321B2 (en) * 2003-05-07 2009-08-27 Samyang Biopharmaceuticals Corporation Highly plastic granules for making fast melting tablets
US8377952B2 (en) * 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
US8025899B2 (en) * 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
US7888412B2 (en) 2004-03-26 2011-02-15 Board Of Trustees Of The University Of Alabama Polymer dissolution and blend formation in ionic liquids
US7550520B2 (en) 2005-05-31 2009-06-23 The University Of Alabama Method of preparing high orientation nanoparticle-containing sheets or films using ionic liquids, and the sheets or films produced thereby
US8883193B2 (en) 2005-06-29 2014-11-11 The University Of Alabama Cellulosic biocomposites as molecular scaffolds for nano-architectures
DE602005007205D1 (de) * 2005-07-19 2008-07-10 Ethypharm Sa Gastroretentive Zusammensetzungen und Verfahren zur Herstellung
GB0612695D0 (en) * 2006-06-27 2006-08-09 Univ Gent Process for preparing a solid dosage form
US20100038816A1 (en) * 2006-08-16 2010-02-18 Novartis Ag Method of making solid dispersions of highly crystalline therapeutic compounds
EP2051696A2 (de) * 2006-08-18 2009-04-29 Morton Grove Pharmaceuticals, Inc. Stabile flüssige levetiracetam-zusammensetzungen und verfahren
CA2672863A1 (en) * 2006-12-19 2008-07-17 Schering-Plough Ltd. Effervescent formulations of florfenicol for addition in drinking water systems
BRPI0810601A2 (pt) * 2007-04-27 2014-10-21 Schering Plough Ltd Compostos e métodos para aumento da solubilidade de florfenicol e antibióticos estruturalmente relacionados usando ciclodextrinas
WO2009105236A1 (en) 2008-02-19 2009-08-27 The Board Of Trustees Of The University Of Alabama Ionic liquid systems for the processing of biomass, their components and/or derivatives, and mixtures thereof
EP2282973A2 (de) * 2008-04-28 2011-02-16 Formac Pharmaceuticals N.v. Geordnetes mesoporöses siliciumdioxidmaterial
FR2935084B1 (fr) * 2008-08-19 2011-05-06 Pancosma Sa Pour L Ind Des Produits Biochimiques Additif pour l'alimentation animale et son procede de preparation
WO2010078300A1 (en) 2008-12-29 2010-07-08 The Board Of Trustees Of The University Of Alabama Dual functioning ionic liquids and salts thereof
WO2010141470A2 (en) 2009-06-01 2010-12-09 The Board Of Trustees Of The University Of Alabama Process for forming films, fibers, and beads from chitinous biomass
US8784691B2 (en) 2009-07-24 2014-07-22 Board Of Trustees Of The University Of Alabama Conductive composites prepared using ionic liquids
BRPI1002023A2 (pt) 2010-03-01 2011-10-25 Nanocore Biotecnologia S A forma farmacêutica sólida de dissolução rápida para tratamento de infecções bacterianas
CN101843586B (zh) * 2010-04-29 2012-05-23 山东迅达康兽药有限公司 一种含有氟苯尼考的可溶于水的微粉及其制备方法
CN102178068B (zh) * 2010-07-06 2013-07-31 新疆农业大学 一种饲料添加剂的使用方法
US9394375B2 (en) 2011-03-25 2016-07-19 Board Of Trustees Of The University Of Alabama Compositions containing recyclable ionic liquids for use in biomass processing
AP2013007268A0 (en) * 2011-05-02 2013-11-30 Aptalis Pharmatech Inc Rapid dissolve tablet compositions for vaginal administration
EP2537518A1 (de) * 2011-06-24 2012-12-26 Elanco Animal Health Ireland Limited Schnell zerfallendene Azaperon-Granulatformulierungen
WO2014106962A1 (ko) 2013-01-07 2014-07-10 삼아제약 주식회사 향상된 용해도를 갖는 신규한 속용성 과립제형
BR102013020508B1 (pt) * 2013-08-12 2021-01-12 Ems S/A. Forma de dosagem que compreende um inibidor de esteroide 5-alfa-redutase e um bloqueador alfa, processo para a preparaçãode uma forma de dosagem e uso da forma de dosagem
US10100131B2 (en) 2014-08-27 2018-10-16 The Board Of Trustees Of The University Of Alabama Chemical pulping of chitinous biomass for chitin
US10011931B2 (en) 2014-10-06 2018-07-03 Natural Fiber Welding, Inc. Methods, processes, and apparatuses for producing dyed and welded substrates
US10982381B2 (en) 2014-10-06 2021-04-20 Natural Fiber Welding, Inc. Methods, processes, and apparatuses for producing welded substrates
AU2016221774B2 (en) 2015-02-17 2020-09-17 Orotech Nv Solid pharmaceutical dosage form suitable for use as drinking water medication
US20200030242A1 (en) * 2016-02-05 2020-01-30 Entrega Inc. Oral dosage form with drying agent for delivery of active agent
CN109069515A (zh) * 2016-03-04 2018-12-21 安比拉神经疗法公司 用于治疗成瘾或物质使用障碍的组合物和方法
US11766835B2 (en) 2016-03-25 2023-09-26 Natural Fiber Welding, Inc. Methods, processes, and apparatuses for producing welded substrates
WO2017192779A1 (en) 2016-05-03 2017-11-09 Natural Fiber Welding, Inc. Methods, processes, and apparatuses for producing dyed and welded substrates
CN108210501B (zh) * 2016-12-14 2019-03-08 中国人民解放军军事医学科学院毒物药物研究所 一种磺酰脲类药物的注射用药物组合物及其制备方法
US10927191B2 (en) 2017-01-06 2021-02-23 The Board Of Trustees Of The University Of Alabama Coagulation of chitin from ionic liquid solutions using kosmotropic salts
US11179377B2 (en) 2017-03-10 2021-11-23 Embera Neurotherapeutics, Inc. Pharmaceutical compositions and uses thereof
US10941258B2 (en) 2017-03-24 2021-03-09 The Board Of Trustees Of The University Of Alabama Metal particle-chitin composite materials and methods of making thereof
TWI829660B (zh) 2017-11-11 2024-01-21 美商天然纖維焊接股份有限公司 紗與熔接紗
MX2021002492A (es) * 2018-09-06 2021-09-08 Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd Formulación antibiótica inyectable de liberación sostenida.
CN114532451B (zh) * 2022-02-28 2023-06-02 安徽科技学院 一种促进肉羊育肥的中药组方添加剂及制备方法
CN115252821A (zh) * 2022-08-10 2022-11-01 四川科宏达集团有限责任公司 一种可溶性氟苯尼考粉的制备方法
CN116019771A (zh) * 2022-09-09 2023-04-28 沈阳伟嘉生物技术有限公司 一种氟苯尼考可混饮无定形固体分散体制剂及其制备方法和用途

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3639637A (en) * 1968-04-23 1972-02-01 Richardson Merrell Inc Water dispersible diethylstilbestrol compositions
US4235892A (en) * 1979-02-05 1980-11-25 Schering Corporation, Patent Dept. 1-Aryl-2-acylamido-3-fluoro-1-propanols, methods for their use as antibacterial agents and compositions useful therefor
IT1196033B (it) * 1984-02-22 1988-11-10 Chiesi Farma Spa Composto ad attivita' antiinfiammatoria ottenuto per complessazione con beta-ciclodestrina e relative formulazioni farmaceutiche
CH666690A5 (de) * 1984-09-14 1988-08-15 Glaxo Group Ltd Antibiotisch wirkende verbindungen der makrolidgruppe aus streptomyces-mikroorganismen, ihre herstellung und verwendung.
DE3440288C2 (de) * 1984-11-05 1987-03-12 Gergely, Gerhard, Dr.-Ing., Wien Pharmazeutische Zubereitung mit einem Gehalt an Ibuprofen sowie Verfahren zu ihrer Herstellung
IT1187751B (it) * 1985-10-15 1987-12-23 Eurand Spa Procedimento per la preparazione di formulazioni solidi di nifedipina ad elevata biodisponibilita' e ad effetto prolungato e formulazioni cosi' ottenute
FR2634376B1 (fr) 1988-07-21 1992-04-17 Farmalyoc Nouvelle forme unitaire, solide et poreuse comprenant des microparticules et/ou des nanoparticules, ainsi que sa preparation
GB8913889D0 (en) 1989-06-16 1989-08-02 May & Baker Ltd New compositions of matter
IT1246188B (it) * 1990-07-27 1994-11-16 Resa Farma Procedimento per la preparazione di composizioni farmaceutiche aventi aumentata velocita' di dissoluzione della sostanza attiva e composizioni ottenute.
US5082863A (en) * 1990-08-29 1992-01-21 Schering Corporation Pharmaceutical composition of florfenicol
WO1993011749A1 (en) * 1991-12-18 1993-06-24 Warner-Lambert Company A process for the preparation of a solid dispersion
US5362860A (en) * 1993-02-01 1994-11-08 Warner-Lambert Company Neutral stabilization complex for CI-979 HCl, a cognition activator
BE1006990A5 (nl) * 1993-04-22 1995-02-07 Univ Gent Werkwijze en samenstelling om een aktief bestanddeel in een vaste toedieningsvorm te brengen.
US5646131A (en) * 1994-02-22 1997-07-08 The Arab Company For Drug Industries And Medical Applicances (Acdima) Method for solubilizing drugs using cyclodextrins and carboxylic acids
HN1998000115A (es) * 1997-08-21 1999-06-02 Warner Lambert Co Formas de dosificación farmacéuticas sólidas
US6153206A (en) * 1997-08-27 2000-11-28 Revlon Consumer Products Corporation Cosmetic compositions
DE69819351D1 (de) 1997-09-11 2003-12-04 Nycomed Danmark As Roskilde Aus mehreren einzeleinheiten zusammengesetzte arzneimittel mit nicht-steroidalen wirkstoffen (nsaids)
US6010719A (en) * 1997-09-16 2000-01-04 Universiteit Gent Freeze-dried disintegrating tablets
US6211185B1 (en) * 1999-05-05 2001-04-03 Veterinary Pharmacy Corporation Concentrate comprising a sulfonamide in solution, a 2,4-diaminopyrimidine in stable suspension within said solution, and a suspending agent
US20010046526A1 (en) * 2000-04-19 2001-11-29 C-Quest Treatment of fungal infections
EP1292381B1 (de) * 2000-05-03 2009-07-15 D'SILVA, Joe Verfahren und vorrichtung zur herstellung von flüssigen verabreichungsformen
AU2002212200A1 (en) * 2000-08-31 2002-03-13 Universiteit Gent Controlled release pharmaceutical pellet compositions for reducing side effects of drugs
US6663897B2 (en) * 2001-02-06 2003-12-16 Dsm Ip Assets B.V. Oral itraconazole formulations and methods of making the same
MXPA04007428A (es) * 2002-02-01 2004-10-11 Pfizer Prod Inc Formas de dosificacion de liberacion inmediata que contienen dispersiones de farmaco solido.
GB0205253D0 (en) * 2002-03-06 2002-04-17 Univ Gent Immediate release pharmaceutical granule compositions and a continuous process for making them

Also Published As

Publication number Publication date
CA2477890A1 (en) 2003-09-12
US8337897B2 (en) 2012-12-25
PT1480622E (pt) 2009-03-06
HK1078006A1 (en) 2006-03-03
CN1638738B (zh) 2012-06-06
TWI296198B (en) 2008-05-01
AU2003215449A1 (en) 2003-09-16
GB0205253D0 (en) 2002-04-17
MXPA04008543A (es) 2004-12-06
AU2003215449B2 (en) 2007-07-26
CA2477890C (en) 2011-05-10
PL208133B1 (pl) 2011-03-31
TW200305446A (en) 2003-11-01
AR038880A1 (es) 2005-02-02
WO2003074031A1 (en) 2003-09-12
ZA200407998B (en) 2006-06-28
MY138752A (en) 2009-07-31
BR0308231A (pt) 2004-12-28
EP1480622B1 (de) 2008-12-24
CN1638738A (zh) 2005-07-13
US20110027377A1 (en) 2011-02-03
US20050058705A1 (en) 2005-03-17
US8349366B2 (en) 2013-01-08
DK1480622T3 (da) 2009-02-16
EP1480622A1 (de) 2004-12-01
US20110008454A1 (en) 2011-01-13
DE60325461D1 (de) 2009-02-05
ES2318147T3 (es) 2009-05-01
PL372579A1 (en) 2005-07-25
SA03240089B1 (ar) 2008-07-12
KR20040091099A (ko) 2004-10-27
US20070009592A1 (en) 2007-01-11

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