ATE419228T1 - Herstellung von fluoromethyl-2,2,2-trifluoro-1- (trifluoromethyl)ethylether - Google Patents

Herstellung von fluoromethyl-2,2,2-trifluoro-1- (trifluoromethyl)ethylether

Info

Publication number
ATE419228T1
ATE419228T1 AT01922664T AT01922664T ATE419228T1 AT E419228 T1 ATE419228 T1 AT E419228T1 AT 01922664 T AT01922664 T AT 01922664T AT 01922664 T AT01922664 T AT 01922664T AT E419228 T1 ATE419228 T1 AT E419228T1
Authority
AT
Austria
Prior art keywords
fluoromethyl
trifluoro
trifluoromethyl
production
ethyl ether
Prior art date
Application number
AT01922664T
Other languages
English (en)
Inventor
Ashot Khrimian
Barry Jones
Original Assignee
Halocarbon Prod Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Halocarbon Prod Corp filed Critical Halocarbon Prod Corp
Application granted granted Critical
Publication of ATE419228T1 publication Critical patent/ATE419228T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01Preparation of ethers
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01BNON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B7/00Halogens; Halogen acids
    • C01B7/19Fluorine; Hydrogen fluoride
    • C01B7/191Hydrogen fluoride
    • C01B7/195Separation; Purification
    • C01B7/196Separation; Purification by distillation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01Preparation of ethers
    • C07C41/34Separation; Purification; Stabilisation; Use of additives
    • C07C41/40Separation; Purification; Stabilisation; Use of additives by change of physical state, e.g. by crystallisation
    • C07C41/42Separation; Purification; Stabilisation; Use of additives by change of physical state, e.g. by crystallisation by distillation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/02Ethers
    • C07C43/03Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/04Saturated ethers
    • C07C43/12Saturated ethers containing halogen
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/582Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Anesthesiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT01922664T 2000-03-16 2001-03-15 Herstellung von fluoromethyl-2,2,2-trifluoro-1- (trifluoromethyl)ethylether ATE419228T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/527,045 US6469219B1 (en) 2000-03-16 2000-03-16 Production of fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether

Publications (1)

Publication Number Publication Date
ATE419228T1 true ATE419228T1 (de) 2009-01-15

Family

ID=24099874

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01922664T ATE419228T1 (de) 2000-03-16 2001-03-15 Herstellung von fluoromethyl-2,2,2-trifluoro-1- (trifluoromethyl)ethylether

Country Status (15)

Country Link
US (1) US6469219B1 (de)
EP (3) EP2272816A1 (de)
JP (4) JP4112862B2 (de)
KR (3) KR100685072B1 (de)
CN (2) CN100509735C (de)
AT (1) ATE419228T1 (de)
AU (1) AU2001249438A1 (de)
BR (1) BR0109376A (de)
CA (3) CA2691933A1 (de)
CZ (1) CZ304716B6 (de)
DE (2) DE60137206D1 (de)
ES (2) ES2319162T3 (de)
HU (1) HUP0300589A3 (de)
PL (1) PL202495B1 (de)
WO (1) WO2001068577A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6469219B1 (en) * 2000-03-16 2002-10-22 Halocarbon Products Corporation Production of fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether
WO2004065340A1 (en) 2003-01-14 2004-08-05 Baxter International Inc. Process for recovery of 1,1,1,3,3,3-hexafluoroisopropanol from the waste stream of sevoflurane synthesis
BRPI0506698A (pt) * 2004-01-05 2007-05-02 Halocarbon Prod Corp método cromatográfico para a análise tanto no processo quanto no sevoflurano acabado
CA2597788C (en) * 2005-02-15 2013-07-09 Halocarbon Products Corporation Separation/purification of desflurane from hydrogen fluoride
DK1910258T3 (da) * 2005-08-04 2012-05-07 Halocarbon Prod Corp Oprensning af fluormethyl-1,1,1,3,3,3-hexafluorisopropylether (sevofluran)
JP5315609B2 (ja) * 2006-06-05 2013-10-16 ダイキン工業株式会社 新規カルボン酸化合物、その用途及びその製造方法
JP5114880B2 (ja) * 2006-07-06 2013-01-09 ダイキン工業株式会社 新規α−フルオロメトキシカルボン酸エステル、該α−フルオロメトキシカルボン酸エステルの製造方法及びセボフルランの製造方法
CN100484910C (zh) * 2006-09-08 2009-05-06 山东新时代药业有限公司 七氟烷生产过程中的副产物提取及转化为六氟异丙醇
JP5163064B2 (ja) * 2007-11-13 2013-03-13 ダイキン工業株式会社 新規カルボン酸エステル、その用途及びその製造方法
US7732647B2 (en) * 2007-12-27 2010-06-08 Halocarbon Products Corporation Process for the purification of fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl ether (sevoflurane)
US20090275785A1 (en) 2008-05-01 2009-11-05 Barry Jones Distillation Method For The Purification Of Sevoflurane And The Maintenance Of Certain Equipment That May Be Used In The Distillation Process
CN101659603B (zh) 2008-08-27 2014-05-07 中化蓝天集团有限公司 一种制备氟甲基-1,1,1,3,3,3-六氟异丙基醚的方法
JP5434236B2 (ja) 2009-04-28 2014-03-05 セントラル硝子株式会社 フルオロメチルヘキサフルオロイソプロピルエーテルの製造方法
US9102604B1 (en) 2010-02-15 2015-08-11 Baxter International Inc. Methods for cleaning distilling columns
DE102011077681A1 (de) 2011-06-17 2012-12-20 Evonik Degussa Gmbh Verfahren zur Herstellung von 3-Cyano-3,5,5-trimethylcyclohexanon
US8729313B2 (en) 2011-08-15 2014-05-20 Baxter International Inc. Process for the manufacturing of sevoflurane
EP4108651A4 (de) * 2020-03-19 2024-05-01 Central Glass Company, Limited Verfahren zur herstellung von (hydro)halogenkohlenstoff
CN113943214B (zh) * 2021-11-11 2023-12-19 福建海西联合药业有限公司 一种运用于七氟烷生产的工艺
CN120025236B (zh) * 2025-04-21 2025-06-27 江苏恒瑞医药股份有限公司 一种制备七氟烷及其中间体的方法

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2425752A (en) * 1944-09-15 1947-08-19 Phillips Petroleum Co Separation of hydrogen fluoride from water and organic contaminants by distillation and decantation
US2992276A (en) * 1959-05-20 1961-07-11 Du Pont Process for preparing polyfluoro alkyl compounds
US3911024A (en) 1966-12-08 1975-10-07 Louise S Croix Fluorinated isopropyl derivatives
US3689571A (en) * 1970-07-31 1972-09-05 Baxter Laboratories Inc Fluorinated ether
US3683092A (en) * 1970-07-31 1972-08-08 Baxter Laboratories Inc Method of anesthesia
US3773907A (en) * 1971-03-09 1973-11-20 Buss Ag Process for the production of pure concentrated hf from impure fluosilicic acid
US3897502A (en) 1971-10-22 1975-07-29 Airco Inc Process for making fluorinated ethers
USRE29084E (en) * 1974-04-17 1976-12-21 Universal Oil Products Company Separate recycle of regenerated acid and of isoparaffin from HF catalyst regeneration zone
US4469898A (en) * 1979-12-26 1984-09-04 Baxter Travenol Laboratories, Inc. Method of synthesizing fluoromethylhexafluoroisopropyl ether
US4250334A (en) * 1979-12-26 1981-02-10 Baxter Travenol Laboratories, Inc. Method of synthesizing fluoromethylhexafluoroisopropyl ether
US4314087A (en) * 1979-12-26 1982-02-02 Baxter Travenol Laboratories, Inc. Methods of synthesizing hexafluoroisopropanol from impure mixtures and synthesis of a fluoromethyl ether therefrom
US4874901A (en) 1988-05-06 1989-10-17 Boc, Inc. Process for the production of polyfluorinated ethers
US4874902A (en) 1988-05-20 1989-10-17 Boc, Inc. Method for the preparation of fluoromethyl 1,1,1,3,3,3-hexafluoro-2-propyl ether
DK0518506T3 (da) * 1991-06-14 1998-03-30 Ici Plc Fremstilling af bis-(fluomethyl)-ether og difluormethan
GB9124087D0 (en) * 1991-11-13 1992-01-02 Ici Plc Chemical process
JPH0532568A (ja) * 1991-07-31 1993-02-09 Daikin Ind Ltd フツ化水素とジクロロフルオロメタンの混合物からフツ化水素を除去する方法
CA2068068A1 (en) * 1991-08-30 1993-03-01 James H. Mestepey Recovery of anhydrous hydrogen fluoride from depleted uranium
GB9126355D0 (en) * 1991-12-11 1992-02-12 Ici Plc Production of hydrofluorocarbons
GB9208769D0 (en) * 1992-04-23 1992-06-10 Ici Plc Production of bis (fluoromethyl) ether and difluoromethane
JP2865554B2 (ja) * 1994-04-08 1999-03-08 セントラル硝子株式会社 フルオロメチル−1,1,1,3,3,3−ヘキサフルオロイソプロピルエーテルのガスクロマトグラフ分析
GB9600072D0 (en) * 1996-01-04 1996-03-06 Ici Plc Process for the production of fluoromethylhexafluoroisopropylether
JP3240043B2 (ja) * 1996-01-23 2001-12-17 セントラル硝子株式会社 フルオロメチル−1,1,1,3,3,3−ヘキサフルオロイソプロピルエーテルの精製方法
ES2169345T5 (es) 1996-02-21 2005-05-01 Central Glass Company, Limited Procedimiento de preparacion de eter de fluorometilo 1,1,1,3,3,3-hexafluoroisopropilico.
US6352677B1 (en) * 1996-06-04 2002-03-05 Alliedsignal, Inc. Process to produce commercial grade anhydrous hydrogen fluoride (AHF) and uranium oxide from the delfuorination of uranium hexafluoride (UF6)
GB9616879D0 (en) * 1996-08-10 1996-09-25 Ici Plc Removal of water from process streams
US5705710A (en) 1997-01-15 1998-01-06 University Of Iowa Research Foundation Process for the synthesis of hexafluoroisopropyl ethers
US5969193A (en) 1997-08-18 1999-10-19 Medeva Pharmaceuticals Pa, Inc. Method for the preparation of sevoflurane
US5886239A (en) 1997-11-21 1999-03-23 Baxter International Inc. Method of preparing monofluoromethyl ethers
US6469219B1 (en) * 2000-03-16 2002-10-22 Halocarbon Products Corporation Production of fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether

Also Published As

Publication number Publication date
PL365368A1 (en) 2004-12-27
DE08173108T1 (de) 2009-08-13
CN100509735C (zh) 2009-07-08
CA2689573A1 (en) 2001-09-20
EP1268381A4 (de) 2004-10-20
JP2008143915A (ja) 2008-06-26
DE60137206D1 (de) 2009-02-12
JP5711050B2 (ja) 2015-04-30
JP5086118B2 (ja) 2012-11-28
KR20020082886A (ko) 2002-10-31
EP2272816A1 (de) 2011-01-12
PL202495B1 (pl) 2009-06-30
KR20050105289A (ko) 2005-11-03
KR100685072B1 (ko) 2007-02-22
AU2001249438A1 (en) 2001-09-24
CA2691933A1 (en) 2001-09-20
CA2689573C (en) 2012-05-22
KR100698653B1 (ko) 2007-03-23
EP2036877A2 (de) 2009-03-18
CZ304716B6 (cs) 2014-09-10
KR20050107528A (ko) 2005-11-11
ES2320720T1 (es) 2009-05-28
CN1636864A (zh) 2005-07-13
CA2403105A1 (en) 2001-09-20
KR100685070B1 (ko) 2007-02-22
EP1268381B1 (de) 2008-12-31
HUP0300589A3 (en) 2003-10-28
EP2036877B1 (de) 2015-08-12
JP4112862B2 (ja) 2008-07-02
EP2036877A3 (de) 2009-07-15
ES2319162T3 (es) 2009-05-05
CN100515926C (zh) 2009-07-22
CA2403105C (en) 2010-02-16
JP2014005287A (ja) 2014-01-16
JP2003530323A (ja) 2003-10-14
CZ20023069A3 (cs) 2003-05-14
JP2011207902A (ja) 2011-10-20
WO2001068577A1 (en) 2001-09-20
HUP0300589A2 (hu) 2003-07-28
US6469219B1 (en) 2002-10-22
EP1268381A1 (de) 2003-01-02
CN1430592A (zh) 2003-07-16
BR0109376A (pt) 2004-01-13

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