ATE420157T1 - Zielgerichtete genveraenderung mit parvoviralen vektoren - Google Patents

Zielgerichtete genveraenderung mit parvoviralen vektoren

Info

Publication number
ATE420157T1
ATE420157T1 AT98919818T AT98919818T ATE420157T1 AT E420157 T1 ATE420157 T1 AT E420157T1 AT 98919818 T AT98919818 T AT 98919818T AT 98919818 T AT98919818 T AT 98919818T AT E420157 T1 ATE420157 T1 AT E420157T1
Authority
AT
Austria
Prior art keywords
genetic modification
parvoviral vectors
targeted genetic
parvoviral
vectors
Prior art date
Application number
AT98919818T
Other languages
English (en)
Inventor
David Russell
Roli Hirata
Original Assignee
Univ Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Washington filed Critical Univ Washington
Application granted granted Critical
Publication of ATE420157T1 publication Critical patent/ATE420157T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Gyroscopes (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Electrotherapy Devices (AREA)
AT98919818T 1997-04-24 1998-04-20 Zielgerichtete genveraenderung mit parvoviralen vektoren ATE420157T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4478997P 1997-04-24 1997-04-24

Publications (1)

Publication Number Publication Date
ATE420157T1 true ATE420157T1 (de) 2009-01-15

Family

ID=21934349

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98919818T ATE420157T1 (de) 1997-04-24 1998-04-20 Zielgerichtete genveraenderung mit parvoviralen vektoren

Country Status (8)

Country Link
US (2) US7972856B2 (de)
EP (1) EP0981604B1 (de)
JP (1) JP2001522244A (de)
AT (1) ATE420157T1 (de)
AU (1) AU744445B2 (de)
CA (2) CA2797661C (de)
DE (1) DE69840439D1 (de)
WO (1) WO1998048005A1 (de)

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AU744445B2 (en) 1997-04-24 2002-02-21 University Of Washington Targeted gene modification by parvoviral vectors
US6054312A (en) 1997-08-29 2000-04-25 Selective Genetics, Inc. Receptor-mediated gene delivery using bacteriophage vectors
NZ522840A (en) 2000-06-01 2004-12-24 Univ North Carolina A parvovirus vector that carries a duplexed genome resulting in co-packaging of strands of plus and minus polarity tethered together
US8105831B2 (en) 2007-03-09 2012-01-31 University Of Washington Parvoviral production of HLA homozygous cells
EP2625278A1 (de) 2010-10-08 2013-08-14 Regents of the University of Minnesota Verfahren zur erhöhung der gentargeting-frequenz
EP2711428A1 (de) 2012-09-21 2014-03-26 Lonza Biologics plc. Ortsspezifische Integration
CN106460009A (zh) 2014-03-21 2017-02-22 小利兰·斯坦福大学托管委员会 无核酸酶的基因组编辑
KR20230067694A (ko) 2014-09-24 2023-05-16 시티 오브 호프 고효율 게놈 편집을 위한 아데노-관련 바이러스 벡터 변이체 및 이의 방법
US10584363B2 (en) 2016-06-03 2020-03-10 Takara Bio Usa, Inc. Methods of producing and using single-stranded deoxyribonucleic acids and compositions for use in practicing the same
WO2018083606A1 (en) 2016-11-01 2018-05-11 Novartis Ag Methods and compositions for enhancing gene editing
ES2979232T3 (es) 2017-03-31 2024-09-25 Cellectis Sa Células inmunitarias con receptor de antígeno quimérico anti-CD22 universal
US20190256867A1 (en) 2018-02-01 2019-08-22 Homology Medicines, Inc. Adeno-associated virus compositions for restoring pah gene function and methods of use thereof
US10610606B2 (en) 2018-02-01 2020-04-07 Homology Medicines, Inc. Adeno-associated virus compositions for PAH gene transfer and methods of use thereof
CN112041437A (zh) 2018-02-19 2020-12-04 同源药物公司 用于恢复f8基因功能的腺相关病毒组合物和其使用方法
TW202140791A (zh) 2020-01-13 2021-11-01 美商霍蒙拉奇醫藥公司 治療苯酮尿症之方法
US20230111672A1 (en) * 2020-04-27 2023-04-13 The Regents Of The University Of California Compositions and methods for production of recombinant adeno-associated virus
TW202208632A (zh) 2020-05-27 2022-03-01 美商同源醫藥公司 用於恢復ｐａｈ基因功能的腺相關病毒組成物及其使用方法
EP4157301A4 (de) * 2020-06-02 2025-03-19 Janssen Biotech, Inc. Materialien und verfahren zur virusreinigung

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US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
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US5464764A (en) * 1989-08-22 1995-11-07 University Of Utah Research Foundation Positive-negative selection methods and vectors
EP0502976B1 (de) 1989-12-01 1996-07-03 Pharming B.V. Herstellung rekombinanter polypeptide durch rinder und transgene methoden
AU7906691A (en) 1990-05-23 1991-12-10 United States of America, as represented by the Secretary, U.S. Department of Commerce, The Adeno-associated virus (aav)-based eucaryotic vectors
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WO1994028884A1 (en) 1993-06-15 1994-12-22 Glyzinc Pharmaceuticals Limited Zinc monoglycerolate complex for anti-rejection treatment of the human or animal body
DE69433592T2 (de) * 1993-11-09 2005-02-10 Targeted Genetics Corp., Seattle Die erzielung hoher titer des rekombinanten aav-vektors
US5604090A (en) 1994-06-06 1997-02-18 Fred Hutchinson Cancer Research Center Method for increasing transduction of cells by adeno-associated virus vectors
US5843780A (en) * 1995-01-20 1998-12-01 Wisconsin Alumni Research Foundation Primate embryonic stem cells
US5814300A (en) * 1995-03-03 1998-09-29 Cephalon, Inc. Gene-targeted non-human mammals deficient in the SOD-1 gene
US5773289A (en) * 1995-06-06 1998-06-30 University Of Pittsburgh AAV directed targeted integration
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US5801030A (en) * 1995-09-01 1998-09-01 Genvec, Inc. Methods and vectors for site-specific recombination
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Also Published As

Publication number Publication date
EP0981604A4 (de) 2002-10-25
JP2001522244A (ja) 2001-11-13
US8846387B2 (en) 2014-09-30
EP0981604A1 (de) 2000-03-01
US20120070890A1 (en) 2012-03-22
WO1998048005A1 (en) 1998-10-29
US20110097804A1 (en) 2011-04-28
US7972856B2 (en) 2011-07-05
CA2797661C (en) 2015-06-16
CA2797661A1 (en) 1998-10-29
AU744445B2 (en) 2002-02-21
CA2289277C (en) 2013-02-12
AU7252198A (en) 1998-11-13
DE69840439D1 (de) 2009-02-26
CA2289277A1 (en) 1998-10-29
EP0981604B1 (de) 2009-01-07

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