ATE420653T1 - Von tryptophanyl-trna-synthetase stammende polypeptide zur regulierung der angiogenese - Google Patents

Von tryptophanyl-trna-synthetase stammende polypeptide zur regulierung der angiogenese

Info

Publication number
ATE420653T1
ATE420653T1 AT02802957T AT02802957T ATE420653T1 AT E420653 T1 ATE420653 T1 AT E420653T1 AT 02802957 T AT02802957 T AT 02802957T AT 02802957 T AT02802957 T AT 02802957T AT E420653 T1 ATE420653 T1 AT E420653T1
Authority
AT
Austria
Prior art keywords
polypeptide
tryptophanyl
sequence
encodes
trna synthetase
Prior art date
Application number
AT02802957T
Other languages
English (en)
Inventor
Paul Schimmel
Keisuke Wakasugi
Martin Friedlander
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Application granted granted Critical
Publication of ATE420653T1 publication Critical patent/ATE420653T1/de

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y601/00—Ligases forming carbon-oxygen bonds (6.1)
    • C12Y601/01—Ligases forming aminoacyl-tRNA and related compounds (6.1.1)
    • C12Y601/01002—Tryptophan-tRNA ligase (6.1.1.2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
AT02802957T 2001-02-23 2002-02-22 Von tryptophanyl-trna-synthetase stammende polypeptide zur regulierung der angiogenese ATE420653T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27095101P 2001-02-23 2001-02-23

Publications (1)

Publication Number Publication Date
ATE420653T1 true ATE420653T1 (de) 2009-01-15

Family

ID=23033541

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02802957T ATE420653T1 (de) 2001-02-23 2002-02-22 Von tryptophanyl-trna-synthetase stammende polypeptide zur regulierung der angiogenese

Country Status (18)

Country Link
US (1) US20030017564A1 (de)
EP (2) EP2080520A1 (de)
JP (2) JP4361734B2 (de)
KR (1) KR100869914B1 (de)
CN (1) CN100486992C (de)
AT (1) ATE420653T1 (de)
AU (2) AU2002306558B2 (de)
BR (1) BR0207449A (de)
CA (1) CA2438273C (de)
DE (1) DE60230860D1 (de)
ES (1) ES2318063T3 (de)
IL (3) IL157558A0 (de)
MX (1) MXPA03007586A (de)
NZ (1) NZ528193A (de)
PL (1) PL208008B1 (de)
RU (1) RU2297425C2 (de)
WO (1) WO2002067970A1 (de)
ZA (1) ZA200307383B (de)

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US7838290B2 (en) * 2002-07-25 2010-11-23 The Scripps Research Institute Hematopoietic stem cells and methods of treatment of neovascular eye diseases therewith
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US20060079672A1 (en) * 2004-10-07 2006-04-13 Paul Glidden Kits for modulating angiogenesis
US8282921B2 (en) 2004-08-02 2012-10-09 Paul Glidden tRNA synthetase fragments
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US20060078556A1 (en) * 2004-10-07 2006-04-13 Paul Glidden Antibodies and epitopes specific to tRNA synthetase fragments
US20060078553A1 (en) * 2004-10-07 2006-04-13 Paul Glidden Diverse multi-unit complexes including a tRNA synthetase fragment
US20060079673A1 (en) * 2004-08-02 2006-04-13 Paul Glidden Polynucleotides encoding tRNA synthetase fragments and uses thereof
US20060024286A1 (en) * 2004-08-02 2006-02-02 Paul Glidden Variants of tRNA synthetase fragments and uses thereof
US20060079473A1 (en) * 2004-10-07 2006-04-13 Paul Glidden Multi-unit complexes and uses thereof
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Also Published As

Publication number Publication date
ZA200307383B (en) 2005-03-30
EP1377305B1 (de) 2009-01-14
US20030017564A1 (en) 2003-01-23
EP2080520A1 (de) 2009-07-22
IL201755A (en) 2015-01-29
AU2007219318A1 (en) 2007-10-18
DE60230860D1 (de) 2009-03-05
AU2002306558B2 (en) 2007-06-28
JP2004532010A (ja) 2004-10-21
JP4361734B2 (ja) 2009-11-11
ES2318063T3 (es) 2009-05-01
BR0207449A (pt) 2004-04-06
PL208008B1 (pl) 2011-03-31
IL157558A (en) 2010-06-16
JP2009261409A (ja) 2009-11-12
CN1527719A (zh) 2004-09-08
EP1377305A1 (de) 2004-01-07
CA2438273C (en) 2013-06-18
WO2002067970A1 (en) 2002-09-06
MXPA03007586A (es) 2003-12-11
JP4448925B2 (ja) 2010-04-14
AU2007219318B2 (en) 2009-12-17
KR100869914B1 (ko) 2008-11-21
IL157558A0 (en) 2004-03-28
RU2297425C2 (ru) 2007-04-20
EP1377305A4 (de) 2005-02-09
HK1069322A1 (zh) 2005-05-20
NZ528193A (en) 2006-02-24
CA2438273A1 (en) 2002-09-06
RU2003128420A (ru) 2005-02-20
PL364596A1 (en) 2004-12-13
KR20030078935A (ko) 2003-10-08
CN100486992C (zh) 2009-05-13

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