ATE422362T1 - Vakzine und verwendung davon zur behandlung amyotrophischer lateralsklerose - Google Patents

Vakzine und verwendung davon zur behandlung amyotrophischer lateralsklerose

Info

Publication number: ATE422362T1
Authority: AT; Austria
Prior art keywords: cop; lateral sclerosis; amyotrophic lateral; vaccines; treating amyotrophic
Prior art date: 2001-12-06

Application number

AT02788511T

Other languages

English (en)

Inventor

Michal Eisenbach-Schwartz

Esther Yoles

Original Assignee

Yeda Res & Dev

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-12-06

Filing date

2002-12-05

Publication date

2009-02-15

2002-12-05 Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev

2009-02-15 Application granted granted Critical

2009-02-15 Publication of ATE422362T1 publication Critical patent/ATE422362T1/de

Links

206010002026 amyotrophic lateral sclerosis Diseases 0.000 title abstract 3
229960005486 vaccine Drugs 0.000 title abstract 2
WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 abstract 3
208000026072 Motor neurone disease Diseases 0.000 abstract 2
239000013543 active substance Substances 0.000 abstract 2
108090000765 processed proteins & peptides Proteins 0.000 abstract 2
206010061818 Disease progression Diseases 0.000 abstract 1
206010056677 Nerve degeneration Diseases 0.000 abstract 1
239000002671 adjuvant Substances 0.000 abstract 1
230000005750 disease progression Effects 0.000 abstract 1
229930195712 glutamate Natural products 0.000 abstract 1
229920001184 polypeptide Polymers 0.000 abstract 1
102000004196 processed proteins & peptides Human genes 0.000 abstract 1
230000001988 toxicity Effects 0.000 abstract 1
231100000419 toxicity Toxicity 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0007—Nervous system antigens; Prions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Immunology (AREA)
Mycology (AREA)
Microbiology (AREA)
Rheumatology (AREA)
Ophthalmology & Optometry (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)

AT02788511T 2001-12-06 2002-12-05 Vakzine und verwendung davon zur behandlung amyotrophischer lateralsklerose ATE422362T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US33613901P	2001-12-06	2001-12-06

Publications (1)

Publication Number	Publication Date
ATE422362T1 true ATE422362T1 (de)	2009-02-15

Family

ID=23314742

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02788511T ATE422362T1 (de)	2001-12-06	2002-12-05	Vakzine und verwendung davon zur behandlung amyotrophischer lateralsklerose

Country Status (23)

Country	Link
US (1)	US7351686B2 (de)
EP (1)	EP1429800B1 (de)
JP (1)	JP4542339B2 (de)
KR (1)	KR20040081431A (de)
CN (2)	CN1617736A (de)
AT (1)	ATE422362T1 (de)
AU (1)	AU2002353486B2 (de)
CA (1)	CA2469092C (de)
CY (1)	CY1109044T1 (de)
DE (1)	DE60231131D1 (de)
DK (1)	DK1429800T3 (de)
ES (1)	ES2322566T3 (de)
HU (1)	HU228207B1 (de)
IL (1)	IL160105A0 (de)
IS (1)	IS2670B (de)
MX (1)	MXPA04005537A (de)
NO (1)	NO336231B1 (de)
NZ (1)	NZ533356A (de)
PL (1)	PL205469B1 (de)
PT (1)	PT1429800E (de)
RU (1)	RU2303996C2 (de)
SI (1)	SI1429800T1 (de)
WO (1)	WO2003047500A2 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7399740B2 (en)	2001-06-28	2008-07-15	Yeda Research And Development Co. Ltd.	Poly-Glu,Tyr for neuroprotective therapy
CA2512735C (en) *	2003-01-07	2016-03-08	Yeda Research And Development Co. Ltd.	Eye-drop vaccine containing copolymer 1 for therapeutic immunization
EP2301569B1 (de)	2003-11-12	2018-05-02	Yeda Research and Development Co. Ltd.	Impfstoff und Verfahren zur Behandlung neurodegenerativer Krankheiten
CA2548310C (en)	2003-12-09	2014-02-18	Yeda Research And Development Co. Ltd.	Method and vaccine comprising copolymer 1 for treatment of psychiatric disorders
AU2005218625A1 (en) *	2004-03-03	2005-09-15	Teva Pharmaceutical Industries, Ltd.	Combination therapy with glatiramer acetate and riluzole
US7655221B2 (en)	2004-05-07	2010-02-02	Peptimmune, Inc.	Methods of treating disease with random copolymers
MXPA06012864A (es) *	2004-05-07	2007-07-18	Peptimmune Inc	Metodo de tratamiento de enfermedades con copolimeros aleatorios.
CA2615506A1 (en)	2005-07-15	2007-01-25	Novartis Ag	Pamps, pathogen associated molecular patterns
CN100448481C (zh) *	2006-06-22	2009-01-07	中国科学院遗传与发育生物学研究所	xCT蛋白及其编码基因的新用途
EP2195008A1 (de)	2007-09-24	2010-06-16	Hadasit Medical Research Services & Development Ltd.	Verwendung von copolymer 1 zur behandlung von muskeldystrophie
USRE49251E1 (en)	2010-01-04	2022-10-18	Mapi Pharma Ltd.	Depot systems comprising glatiramer or pharmacologically acceptable salt thereof
US8759302B2 (en) *	2010-03-16	2014-06-24	Teva Pharmaceutical Industries, Ltd.	Methods of treating a subject afflicted with an autoimmune disease using predictive biomarkers of clinical response to glatiramer acetate therapy in multiple sclerosis
PL2627669T3 (pl)	2010-10-11	2017-02-28	Teva Pharmaceutical Industries Ltd.	Biomarkery cytokinowe jako biomarkery prognostyczne odpowiedzi klinicznej na octan glatirameru
EP2699317B1 (de)	2011-04-21	2016-08-10	Mapi Pharma Limited	Zufallspentapolymer zur behandlung von autoimmunkrankheiten
EP2765857A4 (de)	2011-10-10	2015-12-09	Teva Pharma	Einzelnukleotidpolymorphismen zur vorhersage des klinischen ansprechens auf glatirameracetat
EP2788017B1 (de) *	2011-12-05	2017-05-31	Ben-Gurion University of The Negev Research and Development Authority	INHIBITOREN VON IgG-A2BG2 ZUR BEHANDLUNG UND DIAGNOSE VON AMYOTROPHISCHER LATERALSKLEROSE
CA2907909A1 (en) *	2012-03-26	2013-10-03	Neuroquest Ltd.	Cellular markers for diagnosis of alzheimer's disease and for alzheimer's disease progression
EP2892353A4 (de)	2012-09-10	2016-10-26	Yeda Res & Dev	Individualisierte immunmodulationstherapie für neurodegenerative erkrankungen, zns-läsionen sowie altersbedingte demenz
US12097292B2 (en)	2016-08-28	2024-09-24	Mapi Pharma Ltd.	Process for preparing microparticles containing glatiramer acetate
AU2017319728B2 (en)	2016-08-31	2024-09-05	Mapi Pharma Ltd	Depot systems comprising glatiramer acetate
MX2019010174A (es)	2017-03-26	2019-10-15	Mapi Pharma Ltd	Sistemas de deposito de glatiramer para el tratamiento de formas progresivas de esclerosis multiple.

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL36670A (en) *	1971-04-21	1974-09-10	Sela M	Therapeutic basic copolymers of amino acids
US3849650A (en)	1973-03-29	1974-11-19	Picker Corp	Automatic x-ray inspection system
US5800808A (en) *	1994-05-24	1998-09-01	Veda Research And Development Co., Ltd.	Copolymer-1 improvements in compositions of copolymers
SE505316C2 (sv) *	1995-10-17	1997-08-04	Kenneth G Haglid	Användning av proteinet S-100b för framställning av läkemedel för nervceller
RU2211697C2 (ru) *	1996-09-27	2003-09-10	Гилфорд Фармасьютикалз Инк.	Способ лечения глутаматных расстройств
AU2868699A (en) *	1998-02-13	1999-08-30	Autoimmune, Inc.	Treatment of multiple sclerosis using cop-1 and th2-enhancing cytokines
US20020072493A1 (en)	1998-05-19	2002-06-13	Yeda Research And Development Co. Ltd.	Activated T cells, nervous system-specific antigens and their uses
US20030108528A1 (en)	1998-05-19	2003-06-12	Michal Eisenbach-Schwartz	Activated t-cells, nervous system-specific antigens and their uses
CA2328612A1 (en)	1998-05-19	1999-11-25	Yeda Research And Development Co., Ltd.	Activated t cells, nervous system-specific antigens and their uses
EP1039929A1 (de)	1998-07-21	2000-10-04	YEDA RESEARCH AND DEVELOPMENT Co. Ltd.	Aktivierten t-zellen und deren verwendung
CA2336238A1 (en)	1998-07-23	2000-02-03	The President And Fellows Of Harvard College	Synthetic peptides and methods of use for autoimmune disease therapies
RU2155063C1 (ru) *	1999-10-20	2000-08-27	Санкт-Петербургская общественная организация "Институт биорегуляции и геронтологии"	Тетрапептид, стимулирующий функциональную активность нейронов, фармакологическое средство на его основе и способ его применения
ATE302020T1 (de)	2000-01-20	2005-09-15	Yeda Res & Dev	Verwendung von copolymer 1- und verwandten peptiden sowie von polypeptiden und damit behandelten t-zellen zur neuroprotektiven therapie
ES2256200T3 (es)	2000-06-07	2006-07-16	Yeda Research And Development Co., Ltd.	El uso de copolimero 1 y peptidos y polipeptidos relacionados, y de celulas t tratadas con los mismos, para neuroproteccion frente a la toxicidad del glutamato.
WO2002076503A1 (en) *	2000-06-20	2002-10-03	Mayo Foundation For Medical Education And Research	Treatment of central nervous system diseases by antibodies against glatiramer acetate
US6835711B2 (en) *	2001-06-28	2004-12-28	Yeda Research And Development Co. Ltd.	Use of poly-Glu,Tyr for neuroprotective therapy
US7399740B2 (en) *	2001-06-28	2008-07-15	Yeda Research And Development Co. Ltd.	Poly-Glu,Tyr for neuroprotective therapy

2002
- 2002-12-05 AU AU2002353486A patent/AU2002353486B2/en not_active Ceased
- 2002-12-05 EP EP02788511A patent/EP1429800B1/de not_active Expired - Lifetime
- 2002-12-05 KR KR10-2004-7008780A patent/KR20040081431A/ko not_active Ceased
- 2002-12-05 ES ES02788511T patent/ES2322566T3/es not_active Expired - Lifetime
- 2002-12-05 MX MXPA04005537A patent/MXPA04005537A/es active IP Right Grant
- 2002-12-05 SI SI200230800T patent/SI1429800T1/sl unknown
- 2002-12-05 PT PT02788511T patent/PT1429800E/pt unknown
- 2002-12-05 AT AT02788511T patent/ATE422362T1/de active
- 2002-12-05 WO PCT/IL2002/000979 patent/WO2003047500A2/en not_active Ceased
- 2002-12-05 US US10/485,576 patent/US7351686B2/en not_active Expired - Lifetime
- 2002-12-05 PL PL370070A patent/PL205469B1/pl unknown
- 2002-12-05 IL IL16010502A patent/IL160105A0/xx unknown
- 2002-12-05 RU RU2004120536/14A patent/RU2303996C2/ru not_active IP Right Cessation
- 2002-12-05 JP JP2003548761A patent/JP4542339B2/ja not_active Expired - Fee Related
- 2002-12-05 HU HU0500039A patent/HU228207B1/hu not_active IP Right Cessation
- 2002-12-05 DK DK02788511T patent/DK1429800T3/da active
- 2002-12-05 NZ NZ533356A patent/NZ533356A/en not_active IP Right Cessation
- 2002-12-05 CN CNA028277015A patent/CN1617736A/zh active Pending
- 2002-12-05 CA CA2469092A patent/CA2469092C/en not_active Expired - Fee Related
- 2002-12-05 DE DE60231131T patent/DE60231131D1/de not_active Expired - Lifetime
- 2002-12-05 CN CN201110056639.8A patent/CN102151330B/zh not_active Expired - Fee Related
2004
- 2004-06-03 IS IS7296A patent/IS2670B/is unknown
- 2004-07-05 NO NO20042833A patent/NO336231B1/no not_active IP Right Cessation
2009
- 2009-05-06 CY CY20091100485T patent/CY1109044T1/el unknown

Also Published As

Publication number	Publication date
CY1109044T1 (el)	2014-07-02
CA2469092A1 (en)	2003-06-12
NO20042833L (no)	2004-08-12
ES2322566T3 (es)	2009-06-23
RU2004120536A (ru)	2005-03-27
AU2002353486A1 (en)	2003-06-17
HUP0500039A3 (en)	2010-01-28
DK1429800T3 (da)	2009-04-27
SI1429800T1 (sl)	2009-08-31
WO2003047500A3 (en)	2004-03-18
EP1429800B1 (de)	2009-02-11
CN1617736A (zh)	2005-05-18
HK1067043A1 (en)	2005-04-01
RU2303996C2 (ru)	2007-08-10
PT1429800E (pt)	2009-04-27
NO336231B1 (no)	2015-06-22
CN102151330A (zh)	2011-08-17
IL160105A0 (en)	2004-06-20
EP1429800A4 (de)	2006-03-22
DE60231131D1 (de)	2009-03-26
NZ533356A (en)	2006-10-27
KR20040081431A (ko)	2004-09-21
MXPA04005537A (es)	2004-11-01
CN102151330B (zh)	2017-04-12
JP4542339B2 (ja)	2010-09-15
IS2670B (is)	2010-09-15
PL205469B1 (pl)	2010-04-30
AU2002353486B2 (en)	2009-01-15
IS7296A (is)	2004-06-03
JP2005515198A (ja)	2005-05-26
US20050220802A1 (en)	2005-10-06
EP1429800A2 (de)	2004-06-23
HU228207B1 (hu)	2013-01-28
PL370070A1 (en)	2005-05-16
WO2003047500A2 (en)	2003-06-12
CA2469092C (en)	2013-02-19
HUP0500039A2 (hu)	2005-03-29
US7351686B2 (en)	2008-04-01

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2009-10-15

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Publication	Publication Date	Title
ATE422362T1 (de)	2009-02-15	Vakzine und verwendung davon zur behandlung amyotrophischer lateralsklerose
DE69718150D1 (de)	2003-02-06	Peptid-immunogene zur schutzimpfung gegen und behandlung von allergien
SE9302308L (sv)	1995-01-06	Proteinberedning
DE69400799D1 (de)	1996-11-28	Verwendung von riluzol zur behandlung von parkinson und den parkinson-syndromen
CY1110727T1 (el)	2015-06-10	Παρασκευασματα θετικων κατα gram βακτηριων για τη θεραπεια ασθενειων που περιλαμβανουν μια ανοσολογικη δυσρυθμιση
PL324531A1 (en)	1998-06-08	Derivatives of cyclosporin effective against hiv virus
ATE347376T1 (de)	2006-12-15	Behandlung von allergien
WO2003061578A3 (en)	2003-12-04	Compositions for treatment or prevention of bioterrorism
DE60233898D1 (de)	2009-11-12	Transdermales therapeutisches system für parkinson-krankheit mit hohen rotigotin-plasmaspiegeln
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BR0211970A (pt)	2004-09-21	Uso de bibn4096 em combinação com outras drogas antienxaqueca para o tratamento de enxaqueca
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