DK1429800T3 - Vaccine og anvendelse deraf til behandling af amyotrofisk lateral sklerose - Google Patents

Vaccine og anvendelse deraf til behandling af amyotrofisk lateral sklerose

Info

Publication number: DK1429800T3
Authority: DK; Denmark
Prior art keywords: cop; vaccine; lateral sclerosis; amyotrophic lateral; treatment
Prior art date: 2001-12-06

Application number

DK02788511T

Other languages

English (en)

Inventor

Michal Eisenbach-Schwartz

Esther Yoles

Original Assignee

Yeda Res & Dev

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-12-06

Filing date

2002-12-05

Publication date

2009-04-27

2002-12-05 Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev

2009-04-27 Application granted granted Critical

2009-04-27 Publication of DK1429800T3 publication Critical patent/DK1429800T3/da

Links

206010002026 amyotrophic lateral sclerosis Diseases 0.000 title abstract 3
229960005486 vaccine Drugs 0.000 title abstract 2
WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 abstract 3
208000026072 Motor neurone disease Diseases 0.000 abstract 2
239000013543 active substance Substances 0.000 abstract 2
108090000765 processed proteins & peptides Proteins 0.000 abstract 2
206010061818 Disease progression Diseases 0.000 abstract 1
206010056677 Nerve degeneration Diseases 0.000 abstract 1
239000002671 adjuvant Substances 0.000 abstract 1
230000005750 disease progression Effects 0.000 abstract 1
229930195712 glutamate Natural products 0.000 abstract 1
229920001184 polypeptide Polymers 0.000 abstract 1
102000004196 processed proteins & peptides Human genes 0.000 abstract 1
230000001988 toxicity Effects 0.000 abstract 1
231100000419 toxicity Toxicity 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0007—Nervous system antigens; Prions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Immunology (AREA)
Mycology (AREA)
Microbiology (AREA)
Rheumatology (AREA)
Ophthalmology & Optometry (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)

DK02788511T 2001-12-06 2002-12-05 Vaccine og anvendelse deraf til behandling af amyotrofisk lateral sklerose DK1429800T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US33613901P	2001-12-06	2001-12-06
PCT/IL2002/000979 WO2003047500A2 (en)	2001-12-06	2002-12-05	Vaccine and method for treatment of motor neurone diseases

Publications (1)

Publication Number	Publication Date
DK1429800T3 true DK1429800T3 (da)	2009-04-27

Family

ID=23314742

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK02788511T DK1429800T3 (da)	2001-12-06	2002-12-05	Vaccine og anvendelse deraf til behandling af amyotrofisk lateral sklerose

Country Status (23)

Country	Link
US (1)	US7351686B2 (da)
EP (1)	EP1429800B1 (da)
JP (1)	JP4542339B2 (da)
KR (1)	KR20040081431A (da)
CN (2)	CN1617736A (da)
AT (1)	ATE422362T1 (da)
AU (1)	AU2002353486B2 (da)
CA (1)	CA2469092C (da)
CY (1)	CY1109044T1 (da)
DE (1)	DE60231131D1 (da)
DK (1)	DK1429800T3 (da)
ES (1)	ES2322566T3 (da)
HU (1)	HU228207B1 (da)
IL (1)	IL160105A0 (da)
IS (1)	IS2670B (da)
MX (1)	MXPA04005537A (da)
NO (1)	NO336231B1 (da)
NZ (1)	NZ533356A (da)
PL (1)	PL205469B1 (da)
PT (1)	PT1429800E (da)
RU (1)	RU2303996C2 (da)
SI (1)	SI1429800T1 (da)
WO (1)	WO2003047500A2 (da)

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US7399740B2 (en)	2001-06-28	2008-07-15	Yeda Research And Development Co. Ltd.	Poly-Glu,Tyr for neuroprotective therapy
CN102580069B (zh) *	2003-01-07	2015-09-30	耶达研究及发展有限公司	用于治疗性免疫接种的含共聚物1的滴眼用疫苗
WO2005056574A2 (en)	2003-12-09	2005-06-23	Yeda Research And Development Co. Ltd.	Method and vaccine comprising copolymer 1 for treatment of psychiatric disorders
CA2546077C (en)	2003-11-12	2016-07-05	Yeda Research And Development Co. Ltd.	Vaccine and method for treatment of neurodegenerative diseases
AU2005218625A1 (en) *	2004-03-03	2005-09-15	Teva Pharmaceutical Industries, Ltd.	Combination therapy with glatiramer acetate and riluzole
KR20070036062A (ko) *	2004-05-07	2007-04-02	펩팀문, 인코포레이티드	랜덤 공중합체에 의해 질병을 치료하는 방법
US7655221B2 (en)	2004-05-07	2010-02-02	Peptimmune, Inc.	Methods of treating disease with random copolymers
US8165823B2 (en)	2005-07-15	2012-04-24	Novartis Ag	Pamps, pathogen associated molecular patterns
CN100448481C (zh) *	2006-06-22	2009-01-07	中国科学院遗传与发育生物学研究所	xCT蛋白及其编码基因的新用途
US8193147B2 (en)	2007-09-24	2012-06-05	Hadasit Medical Research Services & Development Ltd.	Use of copolymer 1 for treatment of muscular dystrophy
USRE49251E1 (en)	2010-01-04	2022-10-18	Mapi Pharma Ltd.	Depot systems comprising glatiramer or pharmacologically acceptable salt thereof
US8759302B2 (en) *	2010-03-16	2014-06-24	Teva Pharmaceutical Industries, Ltd.	Methods of treating a subject afflicted with an autoimmune disease using predictive biomarkers of clinical response to glatiramer acetate therapy in multiple sclerosis
NZ703122A (en)	2010-10-11	2016-06-24	Teva Pharma	Cytokine biomarkers as predictive biomarkers of clinical response for glatiramer acetate
ES2601892T3 (es)	2011-04-21	2017-02-16	Mapi Pharma Limited	Pentapolímero aleatorio para el tratamiento de enfermedades autoinmunes
KR20140101730A (ko)	2011-10-10	2014-08-20	테바 파마슈티컬 인더스트리즈 리미티드	글라티라머 아세테이트에 대한 임상 반응을 예측하는 데 유용한 단일 뉴클레오티드 다형성
EP2788017B1 (en) *	2011-12-05	2017-05-31	Ben-Gurion University of The Negev Research and Development Authority	INHIBITORS OF IgG-A2BG2 FOR USE IN TREATING AND DIAGNOSING AMYOTROPHIC LATERAL SCLEROSIS
WO2013144957A1 (en) *	2012-03-26	2013-10-03	Yeda Research And Development Co. Ltd. At The Weizmann Institute Of Science	Cellular markers for diagnosis of alzheimer's disease and for alzheimer's disease progression
EP2892353A4 (en)	2012-09-10	2016-10-26	Yeda Res & Dev	INDIVIDUALIZED IMMUNOMODULATION THERAPY FOR NEURODEGENERATIVE ILLNESSES, CNS LESIONS AND AGGREGATIVE DEMENTIA
US12097292B2 (en)	2016-08-28	2024-09-24	Mapi Pharma Ltd.	Process for preparing microparticles containing glatiramer acetate
HUE071047T2 (hu)	2016-08-31	2025-07-28	Mapi Pharma Ltd	Glatiramer-acetátot tartalmazó depórendszerek
CN110382052A (zh)	2017-03-26	2019-10-25	Mapi医药公司	用于治疗进展型形式的多发性硬化症的格拉替雷储库系统

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IL36670A (en) *	1971-04-21	1974-09-10	Sela M	Therapeutic basic copolymers of amino acids
US3849650A (en)	1973-03-29	1974-11-19	Picker Corp	Automatic x-ray inspection system
IL113812A (en) *	1994-05-24	2000-06-29	Yeda Res & Dev	Copolymer-1 pharmaceutical compositions containing it and its use
SE505316C2 (sv) *	1995-10-17	1997-08-04	Kenneth G Haglid	Användning av proteinet S-100b för framställning av läkemedel för nervceller
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US20030108528A1 (en) *	1998-05-19	2003-06-12	Michal Eisenbach-Schwartz	Activated t-cells, nervous system-specific antigens and their uses
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JP2002500199A (ja)	1998-07-21	2002-01-08	イェダリサーチアンドデベロップメントカンパニーリミテッド	活性化ｔ細胞、及びそれらの用途
JP2003521448A (ja)	1998-07-23	2003-07-15	ザ・プレジデント・アンド・フェローズ・オブ・ハーバード・カレッジ	合成ペプチドおよび自己免疫疾患治療のための使用方法
RU2155063C1 (ru) *	1999-10-20	2000-08-27	Санкт-Петербургская общественная организация "Институт биорегуляции и геронтологии"	Тетрапептид, стимулирующий функциональную активность нейронов, фармакологическое средство на его основе и способ его применения
PT1248643E (pt) *	2000-01-20	2005-10-31	Yeda Res & Dev	Utilizacao de copolimero 1 e peptidos e polipeptidos congeneres e de celulas t tratadas co estes compostos para terapia neuroprotectora
DK1294390T3 (da) *	2000-06-07	2006-04-03	Yeda Res & Dev	Anvendelse af copolymer 1 og beslægtede peptider og polypeptider og T-celelr behandlet dermed til neurobeskyttelse mod glutamattoksicitet
WO2002076503A1 (en) *	2000-06-20	2002-10-03	Mayo Foundation For Medical Education And Research	Treatment of central nervous system diseases by antibodies against glatiramer acetate
US6835711B2 (en) *	2001-06-28	2004-12-28	Yeda Research And Development Co. Ltd.	Use of poly-Glu,Tyr for neuroprotective therapy
US7399740B2 (en) *	2001-06-28	2008-07-15	Yeda Research And Development Co. Ltd.	Poly-Glu,Tyr for neuroprotective therapy

2002
- 2002-12-05 IL IL16010502A patent/IL160105A0/xx unknown
- 2002-12-05 NZ NZ533356A patent/NZ533356A/en not_active IP Right Cessation
- 2002-12-05 EP EP02788511A patent/EP1429800B1/en not_active Expired - Lifetime
- 2002-12-05 DE DE60231131T patent/DE60231131D1/de not_active Expired - Lifetime
- 2002-12-05 PT PT02788511T patent/PT1429800E/pt unknown
- 2002-12-05 HU HU0500039A patent/HU228207B1/hu not_active IP Right Cessation
- 2002-12-05 US US10/485,576 patent/US7351686B2/en not_active Expired - Lifetime
- 2002-12-05 ES ES02788511T patent/ES2322566T3/es not_active Expired - Lifetime
- 2002-12-05 SI SI200230800T patent/SI1429800T1/sl unknown
- 2002-12-05 MX MXPA04005537A patent/MXPA04005537A/es active IP Right Grant
- 2002-12-05 RU RU2004120536/14A patent/RU2303996C2/ru not_active IP Right Cessation
- 2002-12-05 CA CA2469092A patent/CA2469092C/en not_active Expired - Fee Related
- 2002-12-05 KR KR10-2004-7008780A patent/KR20040081431A/ko not_active Ceased
- 2002-12-05 CN CNA028277015A patent/CN1617736A/zh active Pending
- 2002-12-05 AT AT02788511T patent/ATE422362T1/de active
- 2002-12-05 PL PL370070A patent/PL205469B1/pl unknown
- 2002-12-05 WO PCT/IL2002/000979 patent/WO2003047500A2/en not_active Ceased
- 2002-12-05 DK DK02788511T patent/DK1429800T3/da active
- 2002-12-05 JP JP2003548761A patent/JP4542339B2/ja not_active Expired - Fee Related
- 2002-12-05 AU AU2002353486A patent/AU2002353486B2/en not_active Ceased
- 2002-12-05 CN CN201110056639.8A patent/CN102151330B/zh not_active Expired - Fee Related
2004
- 2004-06-03 IS IS7296A patent/IS2670B/is unknown
- 2004-07-05 NO NO20042833A patent/NO336231B1/no not_active IP Right Cessation
2009
- 2009-05-06 CY CY20091100485T patent/CY1109044T1/el unknown

Also Published As

Publication number	Publication date
HK1067043A1 (en)	2005-04-01
JP2005515198A (ja)	2005-05-26
ES2322566T3 (es)	2009-06-23
US7351686B2 (en)	2008-04-01
HUP0500039A3 (en)	2010-01-28
HUP0500039A2 (hu)	2005-03-29
KR20040081431A (ko)	2004-09-21
CA2469092C (en)	2013-02-19
CA2469092A1 (en)	2003-06-12
CN102151330A (zh)	2011-08-17
IL160105A0 (en)	2004-06-20
DE60231131D1 (de)	2009-03-26
IS7296A (is)	2004-06-03
PT1429800E (pt)	2009-04-27
WO2003047500A2 (en)	2003-06-12
NZ533356A (en)	2006-10-27
RU2004120536A (ru)	2005-03-27
AU2002353486A1 (en)	2003-06-17
NO20042833L (no)	2004-08-12
IS2670B (is)	2010-09-15
SI1429800T1 (sl)	2009-08-31
EP1429800B1 (en)	2009-02-11
EP1429800A2 (en)	2004-06-23
RU2303996C2 (ru)	2007-08-10
WO2003047500A3 (en)	2004-03-18
PL370070A1 (en)	2005-05-16
JP4542339B2 (ja)	2010-09-15
MXPA04005537A (es)	2004-11-01
ATE422362T1 (de)	2009-02-15
PL205469B1 (pl)	2010-04-30
CN1617736A (zh)	2005-05-18
AU2002353486B2 (en)	2009-01-15
CY1109044T1 (el)	2014-07-02
HU228207B1 (hu)	2013-01-28
CN102151330B (zh)	2017-04-12
US20050220802A1 (en)	2005-10-06
NO336231B1 (no)	2015-06-22
EP1429800A4 (en)	2006-03-22

Publication	Publication Date	Title
DK1429800T3 (da)	2009-04-27	Vaccine og anvendelse deraf til behandling af amyotrofisk lateral sklerose
ATE455561T1 (de)	2010-02-15	Konjugate von zytotoxischen mitteln und biologisch aktiven peptiden
NO20035740L (no)	2004-02-16	Fremgangsmater for a indusere en cytotoksisk immunrespons og rekombinante ape-adenovirussammensetninger nyttige for disse
DE60233898D1 (de)	2009-11-12	Transdermales therapeutisches system für parkinson-krankheit mit hohen rotigotin-plasmaspiegeln
ATE504308T1 (de)	2011-04-15	Antimikrobielle kationische peptide und diese enthaltende formulierungen
BR0109027A (pt)	2003-06-03	Peptìdios derivados de caseìna e usos dos mesmos em terapia
MA28149A1 (fr)	2006-09-01	Compositions de vaccin comprenant une interleukine 18 et un systeme adjuvant de type saponine
MXPA05002814A (es)	2005-05-27	Formulacion para agentes lipofilicos.
BR9916857A (pt)	2001-12-04	4 heteroaril diarilaminas
BG103786A (bg)	2000-10-31	Състав и метод за профилактика и лечение на нiv и други инфекциозни заболявания при човека
DK1409006T3 (da)	2011-06-14	Monodispergerede blandinger og fremgangsmåder til behandling af diabetes
MXPA02005563A (es)	2004-09-10	Formulacion estable de interferon en solucion acuosa, metodo de preparacion y usos de la misma.
ATE458496T1 (de)	2010-03-15	Hiv-vakzine und anwendungsverfahren
EA201000386A1 (ru)	2011-06-30	Нетоксичные для нервной ткани плазминоген-активирующие факторы для лечения инсульта
YU45103A (sh)	2006-08-17	Upotreba sarp/1 za lečenje i prevenciju skleroderme
UY27373A1 (es)	2003-02-28	Formulaciones de interferón beta-humano
MXPA02011533A (es)	2003-04-25	Nuevas formulaciones de alfa-2,4-disulfofenil-n-terc-butilnitrona.
BR0303384A (pt)	2004-03-30	Citalopram e seus usos no tratamento de pressão sanguìnea elevada
PT1150981E (pt)	2003-08-29	Composto nucleosidico terapeutico
HRP20030701A2 (en)	2006-06-30	Natural antibodies active against hiv virus
SE9902674D0 (sv)	1999-07-12	New composition
IT1276453B1 (it)	1997-10-31	Vaccino/composizioni terapautica di helycobacter pylori, loro preparazione ed impiego.
SE9902673D0 (sv)	1999-07-12	New composition