ATE423117T1 - Heterocyclische 7-aminoalkylidenylchinolone und - naphthyridone - Google Patents

Heterocyclische 7-aminoalkylidenylchinolone und - naphthyridone

Info

Publication number
ATE423117T1
ATE423117T1 AT04783671T AT04783671T ATE423117T1 AT E423117 T1 ATE423117 T1 AT E423117T1 AT 04783671 T AT04783671 T AT 04783671T AT 04783671 T AT04783671 T AT 04783671T AT E423117 T1 ATE423117 T1 AT E423117T1
Authority
AT
Austria
Prior art keywords
aminoalkylidenylquinolones
naphthyridones
heterocyclic
Prior art date
Application number
AT04783671T
Other languages
English (en)
Inventor
Grant Iii Eugene Bowers
Mark Joseph Macielag
Xiaoqing Xu
Steven David Paget
Michele Ann Weidner-Wells
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of ATE423117T1 publication Critical patent/ATE423117T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT04783671T 2003-09-22 2004-09-09 Heterocyclische 7-aminoalkylidenylchinolone und - naphthyridone ATE423117T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US50492403P 2003-09-22 2003-09-22

Publications (1)

Publication Number Publication Date
ATE423117T1 true ATE423117T1 (de) 2009-03-15

Family

ID=34421521

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04783671T ATE423117T1 (de) 2003-09-22 2004-09-09 Heterocyclische 7-aminoalkylidenylchinolone und - naphthyridone

Country Status (24)

Country Link
US (1) US7179805B2 (de)
EP (1) EP1675852B1 (de)
JP (2) JP2007522093A (de)
KR (1) KR101137311B1 (de)
CN (1) CN1997642B (de)
AR (1) AR045805A1 (de)
AT (1) ATE423117T1 (de)
AU (1) AU2004278320B2 (de)
BR (1) BRPI0414573A (de)
CA (1) CA2539349C (de)
CY (1) CY1109424T1 (de)
DE (1) DE602004019555D1 (de)
DK (1) DK1675852T3 (de)
ES (1) ES2321722T3 (de)
IL (1) IL174397A (de)
MY (1) MY176860A (de)
NZ (1) NZ545970A (de)
PL (1) PL1675852T3 (de)
PT (1) PT1675852E (de)
RU (1) RU2350615C2 (de)
SI (1) SI1675852T1 (de)
TW (1) TWI359150B (de)
WO (1) WO2005033108A1 (de)
ZA (1) ZA200603223B (de)

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EP2319404B1 (de) * 2003-01-24 2015-03-11 The General Hospital Corporation System und Verfahren zur Gewebeidentifizierung mittels Interferometrie mit niedriger Kohärenz
US7732612B2 (en) * 2004-09-09 2010-06-08 Janssen Pharmaceutica, N.V. 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones
US20090156577A1 (en) * 2004-09-09 2009-06-18 Benjamin Davis 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones
AU2012244358B2 (en) * 2005-03-21 2015-05-28 Janssen Pharmaceutica, N.V. 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones
EP1891037A1 (de) * 2005-06-15 2008-02-27 Hetero Drugs Limited Gemifloxacin-verfahren und - polymorphe
JO2752B1 (en) * 2005-06-28 2014-03-15 شركة جانسين فارماسوتيكا ان. في Quinoline derivatives acting as antibacterial agents
EP1909910A1 (de) 2005-08-04 2008-04-16 Sirtris Pharmaceuticals, Inc. Benzimidazol-derivative als sirtuin-modulatoren
MX2008002414A (es) * 2005-09-02 2008-03-27 Pfizer 1h-imidazopiridinas sustituidas con hidroxi y procedimientos.
SI1954697T1 (sl) * 2005-10-21 2010-05-31 Glaxo Group Ltd Peri kondenzirane triciklične spojine uporabne kot antibakterijska sredstva
ATE465163T1 (de) 2005-12-22 2010-05-15 Glaxo Group Ltd Heterocyclische verbindungen, ihre herstellung und ihre verwendung als antibakterielle mittel
WO2007110835A2 (en) 2006-03-28 2007-10-04 The Procter & Gamble Company A coupling process for preparing quinolone intermediates
PL2001862T3 (pl) * 2006-03-28 2011-09-30 Warner Chilcott Co Llc Jabłczany oraz odmiany polimorficzne kwasu (3S,5S)-7-[3-amino-5-metylo-piperydynylo]-1-cyklopropylo-1,4-dihydro-8-metoksy-4-okso-3-chinolinokarboksylowego
EP1999106B1 (de) 2006-03-28 2012-06-27 TaiGen Biotechnology Co., Ltd. Hybridreduktionsverfahren zur herstellung von chinolon-zwischenverbindungen
US20080009628A1 (en) * 2006-07-05 2008-01-10 Michael Reuman One-Pot Condensation-Reduction Methods for Preparing Substituted Allylic Alcohols
CN101888780B (zh) * 2007-10-05 2014-08-13 生华生物科技股份有限公司 喹诺酮类似物及其相关方法
CA2762022A1 (en) 2009-05-15 2010-11-18 Redx Pharma Limited Redox drug derivatives
MX2012008031A (es) * 2010-01-11 2012-11-12 Janssen Pharmaceutica Nv Profarmacos de acido (e)-7-(3-(2-amino-1-fluoroetiliden)piperidin- 1-il)-1-ciclopropil-6-fluoro-8-metoxi-4-oxo-1,4-dihidroquinolin-3 -carboxilico.
CN104098588B (zh) * 2013-04-02 2016-05-25 广州白云山医药集团股份有限公司白云山制药总厂 一类三环喹诺酮衍生物及其制备方法和用途
AU2015264201A1 (en) * 2014-05-21 2017-01-12 New York University Oxopiperazine helix mimetics for control of hypoxia-inducible gene expression
CA3005730A1 (en) 2015-11-20 2017-05-26 Senhwa Biosciences, Inc. Combination therapy of tetracyclic quinolone analogs for treating cancer
US9957282B2 (en) 2015-12-14 2018-05-01 Senhwa Biosciences, Inc. Crystalline forms of quinolone analogs and their salts
TWI884912B (zh) 2018-02-15 2025-06-01 生華生物科技股份有限公司 喹啉酮類似物及其鹽、組合物及其使用方法
RU2671573C1 (ru) * 2018-09-03 2018-11-02 Алина Викторовна Шумадалова 2-[6-метил-4-(тиетан-3-илокси)пиримидин-2-илтио]ацетогидразид малеиновой кислоты, проявляющий противомикробную активность

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JPS605539B2 (ja) * 1980-03-17 1985-02-12 日東紡績株式会社 耐アルカリ性、耐熱性無機質繊維
FI871419L (fi) * 1986-03-31 1987-10-01 Sankyo Co Kinolin-3-karboxylsyraderivat, deras framstaellning och anvaendning.
JPH0262875A (ja) * 1988-05-23 1990-03-02 Wakunaga Pharmaceut Co Ltd 新規イソインドリン誘導体
CA1332605C (en) * 1988-10-03 1994-10-18 Yasuhiro Nishitani Pyridonecarboxylic acids
US5580872A (en) * 1990-05-02 1996-12-03 Abbott Laboratories Quinolizinone type compounds
FR2681865B1 (fr) * 1991-10-01 1993-11-19 Bel Laboratoire Roger Nouveaux derives de la benzonaphtyridine-1,8 leur preparation et les compositions qui les contiennent.
FR2692577B1 (fr) * 1992-05-26 1996-02-02 Bouchara Sa Nouvelles quinolones fluorees, leur procede de preparation et les compositions pharmaceutiques en renfermant.
JPH06263754A (ja) * 1993-03-12 1994-09-20 Hokuriku Seiyaku Co Ltd ７−アミノピロリジニルキノリン−３−カルボン酸誘導体
ZA944369B (en) * 1993-08-27 1995-02-13 Hokuriku Seuyaku Co Ltd 5-amino-8-methyl-7-pyrrolidinylquinoline-3-carboxylic acid derivative
JPH09503783A (ja) * 1993-10-14 1997-04-15 アボツト・ラボラトリーズ キノリジノン型化合物
US5392154A (en) * 1994-03-30 1995-02-21 Bell Communications Research, Inc. Self-regulating multiwavelength optical amplifier module for scalable lightwave communications systems
KR0131999B1 (ko) * 1994-06-16 1998-04-17 성재갑 7-(4-아미노메틸-3-옥심)피롤리딘 치환제를 갖는 신규 퀴놀린 카르복실산 유도체 및 그의 제조방법
EP0871628A1 (de) * 1995-06-06 1998-10-21 Abbott Laboratories Verbindungen des chinolizinon-typs
EP0882049B1 (de) * 1996-02-23 2002-11-20 Bayer Ag Gegebenenfalls substituierte 8-cyan-1-cyclopropyl-7-(2,8-diazabicyclo- 4.3.0]-nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäuren und ihre derivate
ES2321042T3 (es) * 1997-09-15 2009-06-01 THE PROCTER & GAMBLE COMPANY Quinolonas antimicrobianas, composiciones y usos de las mismas.
KR100330409B1 (ko) * 1998-07-23 2002-08-27 한국과학기술원 파장분할다중 방식 다중화/역다중화 장치와 이를 이용한 파장분할다중 방식 수동형 광 가입자망
US6964966B2 (en) * 2001-04-25 2005-11-15 Wockhardt Limited Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments

Also Published As

Publication number Publication date
SI1675852T1 (sl) 2009-06-30
ZA200603223B (en) 2007-09-26
WO2005033108A1 (en) 2005-04-14
EP1675852B1 (de) 2009-02-18
AU2004278320A1 (en) 2005-04-14
RU2350615C2 (ru) 2009-03-27
KR20060097119A (ko) 2006-09-13
BRPI0414573A (pt) 2006-11-07
ES2321722T3 (es) 2009-06-10
PT1675852E (pt) 2009-03-25
CN1997642B (zh) 2012-06-13
TWI359150B (en) 2012-03-01
IL174397A (en) 2014-01-30
AU2004278320B2 (en) 2010-06-24
KR101137311B1 (ko) 2012-04-23
RU2006109004A (ru) 2007-09-27
DK1675852T3 (da) 2009-05-25
TW200526654A (en) 2005-08-16
JP5431515B2 (ja) 2014-03-05
MY176860A (en) 2020-08-24
PL1675852T3 (pl) 2009-07-31
IL174397A0 (en) 2006-08-01
US7179805B2 (en) 2007-02-20
CY1109424T1 (el) 2014-08-13
CN1997642A (zh) 2007-07-11
NZ545970A (en) 2009-05-31
AR045805A1 (es) 2005-11-16
DE602004019555D1 (de) 2009-04-02
JP2012162529A (ja) 2012-08-30
CA2539349A1 (en) 2005-04-14
JP2007522093A (ja) 2007-08-09
US20050101588A1 (en) 2005-05-12
EP1675852A1 (de) 2006-07-05
CA2539349C (en) 2012-06-05

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