ATE424219T1 - Hemmende antikörper der her3-aktivität - Google Patents
Hemmende antikörper der her3-aktivitätInfo
- Publication number
- ATE424219T1 ATE424219T1 AT02794590T AT02794590T ATE424219T1 AT E424219 T1 ATE424219 T1 AT E424219T1 AT 02794590 T AT02794590 T AT 02794590T AT 02794590 T AT02794590 T AT 02794590T AT E424219 T1 ATE424219 T1 AT E424219T1
- Authority
- AT
- Austria
- Prior art keywords
- inhibiting antibodies
- her3
- her3 activity
- activity
- composition
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01119260A EP1283053A1 (de) | 2001-08-09 | 2001-08-09 | Inhibitore der HER3 Aktivität |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE424219T1 true ATE424219T1 (de) | 2009-03-15 |
Family
ID=8178284
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02794590T ATE424219T1 (de) | 2001-08-09 | 2002-08-09 | Hemmende antikörper der her3-aktivität |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US9011851B2 (de) |
| EP (3) | EP1283053A1 (de) |
| JP (1) | JP5226926B2 (de) |
| CN (2) | CN102078613A (de) |
| AT (1) | ATE424219T1 (de) |
| AU (1) | AU2002333384B2 (de) |
| CA (1) | CA2456723C (de) |
| CY (1) | CY1110322T1 (de) |
| DE (1) | DE60231407D1 (de) |
| DK (1) | DK1414494T3 (de) |
| ES (1) | ES2323772T3 (de) |
| PT (1) | PT1414494E (de) |
| WO (1) | WO2003013602A1 (de) |
Families Citing this family (78)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPQ105799A0 (en) | 1999-06-18 | 1999-07-08 | Victor Chang Cardiac Research Institute, The | Cell growth inhibition |
| EP1283053A1 (de) | 2001-08-09 | 2003-02-12 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Inhibitore der HER3 Aktivität |
| EP2400021B1 (de) | 2002-03-26 | 2016-11-30 | Zensun (Shanghai) Science & Technology, Co., Ltd. | Verfahren und Zusammensetzungen auf ErbB3-Basis zur Behandlung von Neoplasmen |
| US8505468B2 (en) * | 2002-11-19 | 2013-08-13 | Sharp Kabushiki Kaisha | Substrate accommodating tray |
| AR056857A1 (es) * | 2005-12-30 | 2007-10-24 | U3 Pharma Ag | Anticuerpos dirigidos hacia her-3 (receptor del factor de crecimiento epidérmico humano-3) y sus usos |
| AU2007324868B2 (en) | 2006-11-28 | 2014-03-20 | Daiichi Sankyo Europe Gmbh | Activated HER3 as a marker for predicting therapeutic efficacy |
| WO2008100624A2 (en) | 2007-02-16 | 2008-08-21 | Merrimack Pharmaceuticals, Inc. | Antibodies against erbb3 and uses thereof |
| AU2008239594B2 (en) | 2007-04-13 | 2013-10-24 | Beth Israel Deaconess Medical Center | Methods for treating cancer resistant to ErbB therapeutics |
| PE20090321A1 (es) | 2007-06-04 | 2009-04-20 | Genentech Inc | Anticuerpos anti-notch1 nrr, metodo de preparacion y composicion farmaceutica |
| KR101553723B1 (ko) * | 2007-07-13 | 2015-09-16 | 네스텍 소시에테아노님 | 항체기반 어레이를 사용한 폐 암 치료를 위한 약물 선별법 |
| EP2138511A1 (de) * | 2008-06-27 | 2009-12-30 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | HER3 als Determinante für eine Melanomprognose |
| ES2433424T3 (es) * | 2008-08-15 | 2013-12-11 | Merrimack Pharmaceuticals, Inc. | Métodos y sistemas para predecir respuesta de células frente a un agente terapéutico |
| US8470542B2 (en) | 2008-12-01 | 2013-06-25 | Laboratory Corporation Of America Holdings | Methods and assays for measuring p95 and/or p95 complexes in a sample and antibodies specific for p95 |
| CA2749846C (en) | 2009-01-15 | 2018-08-07 | Laboratory Corporation Of America Holdings | Methods of determining patient response by measurement of her-3 |
| WO2010085845A1 (en) * | 2009-01-28 | 2010-08-05 | The University Of Queensland | Cancer therapy and/or diagnosis |
| WO2010108127A1 (en) | 2009-03-20 | 2010-09-23 | Genentech, Inc. | Bispecific anti-her antibodies |
| AU2010242914B2 (en) * | 2009-04-29 | 2014-11-13 | Trellis Bioscience, Llc | Improved antibodies immunoreactive with heregulin-coupled HER3 |
| MX358013B (es) | 2009-11-13 | 2018-08-01 | Amgen Inc | Materiales y metodos para el tratamiento o prevencion de enfermedades asociadas al her-3. |
| HUE029026T2 (en) * | 2009-12-22 | 2017-01-30 | Roche Glycart Ag | ANTI-HER3 Antibodies and uses thereof |
| EP2544680B1 (de) * | 2010-03-11 | 2015-01-14 | Merrimack Pharmaceuticals, Inc. | Verwendung von erbb3-hemmern bei der behandlung von dreifach negativem brustkrebs |
| PH12012502022B1 (en) | 2010-04-09 | 2019-03-08 | Aveo Pharmaceuticals Inc | Anti-erbb3 antibodies |
| AR084469A1 (es) | 2010-07-09 | 2013-05-22 | Exelixis Inc | Combinaciones de inhibidores de quinasas para el tratamiento del cancer |
| AU2011290672B2 (en) | 2010-08-20 | 2015-07-09 | Novartis Ag | Antibodies for epidermal growth factor receptor 3 (HER3) |
| TW201302793A (zh) * | 2010-09-03 | 2013-01-16 | Glaxo Group Ltd | 新穎之抗原結合蛋白 |
| EP2635604B1 (de) | 2010-11-01 | 2016-11-30 | Symphogen A/S | Pan-her-antikörperzusammensetzung |
| KR20140044796A (ko) | 2011-03-11 | 2014-04-15 | 메리맥 파마슈티컬즈, 인크. | 호르몬 무반응 유방암의 치료에서 egfr-패밀리 수용체의 저해제의 용도 |
| EA201301025A1 (ru) | 2011-03-15 | 2014-01-30 | Мерримак Фармасьютикалс, Инк. | Преодоление устойчивости к ингибиторам пути erbb |
| TWI631136B (zh) | 2011-04-19 | 2018-08-01 | 莫瑞麥克製藥公司 | 單特異性及雙特異性抗igf-1r及抗erbb3抗體 |
| ES2657862T3 (es) | 2011-05-13 | 2018-03-07 | Gamamabs Pharma | Anticuerpos contra HER3 |
| CN103890010B (zh) * | 2011-05-19 | 2017-04-19 | 法国国家健康医学研究院 | 抗‑人‑her3抗体及其用途 |
| EP2722343A4 (de) * | 2011-06-20 | 2014-12-17 | Kyowa Hakko Kirin Co Ltd | Anti-erbb3-antikörper |
| SG11201400150TA (en) | 2011-09-30 | 2014-03-28 | Regeneron Pharma | Anti-erbb3 antibodies and uses thereof |
| US9273143B2 (en) | 2011-09-30 | 2016-03-01 | Regeneron Pharmaceuticals, Inc. | Methods and compositions comprising a combination of an anti-ErbB3 antibody and an anti-EGFR antibody |
| AU2012318541B2 (en) | 2011-10-06 | 2018-04-12 | Aveo Pharmaceuticals, Inc. | Predicting tumor response to anti-ERBB3 antibodies |
| CA2855298A1 (en) * | 2011-11-09 | 2013-05-16 | The Uab Research Foundation | Her3 antibodies and uses thereof |
| ES2745684T3 (es) * | 2011-11-23 | 2020-03-03 | Medimmune Llc | Moléculas de unión específicas para HER3 y usos de las mismas |
| US9192663B2 (en) | 2011-12-05 | 2015-11-24 | Novartis Ag | Antibodies for epidermal growth factor receptor 3 (HER3) |
| CN104136464A (zh) | 2012-02-23 | 2014-11-05 | U3制药有限公司 | 用于调节放射敏感性的her3抑制剂 |
| AU2013343667A1 (en) | 2012-11-08 | 2015-04-02 | F. Hoffmann-La Roche Ag | HER3 antigen binding proteins binding to the beta-hairpin of HER3 |
| MA38164B1 (fr) | 2012-11-08 | 2018-11-30 | Hoffmann La Roche | Protéines de liaison à l'antigène anti-her3/her4 se liant à la boucle en épingle à cheveux beta |
| US9695228B2 (en) | 2012-11-21 | 2017-07-04 | Janssen Biotech, Inc. | EGFR and c-Met fibronectin type III domain binding molecules |
| CN113201073A (zh) | 2012-11-21 | 2021-08-03 | 詹森生物科技公司 | 双特异性EGFR/c-Met抗体 |
| US20170275367A1 (en) | 2012-11-21 | 2017-09-28 | Janssen Biotech, Inc. | Bispecific EGFR/C-Met Antibodies |
| US9180185B2 (en) | 2013-01-11 | 2015-11-10 | Hoffman-La Roche Inc. | Combination therapy of anti-HER3 antibodies |
| EP2970494B1 (de) | 2013-03-14 | 2017-12-13 | The Board of Regents of The University of Texas System | Her3-spezifischer monoklonaler antikörper zur diagnostischen und therapeutischen verwendung |
| EP2981828A1 (de) * | 2013-04-05 | 2016-02-10 | Laboratory Corporation of America Holdings | Systeme und verfahren zur erleichterung der diagnose, prognose und behandlung von krebs auf basis der erkennung einer her3-aktivierung |
| EP2821071A1 (de) | 2013-07-04 | 2015-01-07 | Institut d'Investigació Biomèdica de Bellvitge (IDIBELL) | Verbindungen zur Brustkrebsbehandlung |
| US11305012B2 (en) | 2013-09-24 | 2022-04-19 | Medimmune, Llc | Binding molecules specific for HER3 and uses thereof |
| KR20160067966A (ko) | 2013-10-14 | 2016-06-14 | 얀센 바이오테크 인코포레이티드 | 시스테인 조작된 피브로넥틴 iii형 도메인 결합 분자 |
| US10519247B2 (en) * | 2013-11-01 | 2019-12-31 | Board Of Regents,The University Of Texas System | Targeting HER2 and HER3 with bispecific antibodies in cancerous cells |
| EP3087394A2 (de) | 2013-12-27 | 2016-11-02 | Merrimack Pharmaceuticals, Inc. | Biomarkerprofile zur vorhersage der ergebnisse einer krebstherapie mit erbb3-inhibitoren und/oder chemotherapien |
| CN111228511B (zh) | 2014-04-10 | 2024-06-18 | 第一三共株式会社 | 抗her3抗体-药物偶联物 |
| WO2015157634A1 (en) | 2014-04-11 | 2015-10-15 | Kolltan Pharmaceuticals, Inc. | Anti-erbb antibodies and methods of use thereof |
| MX2016014416A (es) | 2014-05-14 | 2017-02-23 | Hoffmann La Roche | Anticuerpos anti-her3 que se unen a la horquilla beta de her3. |
| US10184006B2 (en) | 2015-06-04 | 2019-01-22 | Merrimack Pharmaceuticals, Inc. | Biomarkers for predicting outcomes of cancer therapy with ErbB3 inhibitors |
| EP4385569A3 (de) | 2015-06-24 | 2024-09-25 | Janssen Biotech, Inc. | Immunmodulation und behandlung von soliden tumoren mit spezifisch an cd38 bindenden antikörpern |
| JP6787890B2 (ja) | 2015-06-29 | 2020-11-18 | 第一三共株式会社 | 抗体−薬物コンジュゲートの選択的製造方法 |
| KR102770238B1 (ko) | 2015-09-30 | 2025-02-18 | 얀센 바이오테크 인코포레이티드 | 인간 cd40에 특이적으로 결합하는 작용성 항체 및 사용 방법 |
| EA201990067A1 (ru) | 2016-06-21 | 2019-07-31 | Янссен Байотек, Инк. | Цистеин-модифицированные связывающие молекулы на основе домена фибронектина iii типа |
| TWI862473B (zh) | 2016-12-12 | 2024-11-21 | 日商第一三共股份有限公司 | 抗體-藥物結合物與免疫檢查點抑制劑之組合、以及醫藥組成物之用途 |
| AU2017378226A1 (en) | 2016-12-14 | 2019-06-20 | Janssen Biotech, Inc. | CD8A-binding fibronectin type III domains |
| EP3554561B1 (de) | 2016-12-14 | 2023-06-28 | Janssen Biotech, Inc. | Cd137-bindende fibronectin-typ-iii-domänen |
| US10597438B2 (en) | 2016-12-14 | 2020-03-24 | Janssen Biotech, Inc. | PD-L1 binding fibronectin type III domains |
| TWI780104B (zh) | 2017-01-17 | 2022-10-11 | 日商第一三共股份有限公司 | 抗gpr20抗體及抗gpr20抗體-藥物結合物、以及其製造方法及用途 |
| JP2020510673A (ja) | 2017-03-03 | 2020-04-09 | ヤンセン バイオテツク,インコーポレーテツド | がんの治療のための低分子csf−1r阻害剤とcd40に特異的に結合するアゴニスト抗体とを含む併用療法 |
| TWI855528B (zh) | 2017-05-15 | 2024-09-11 | 日商第一三共股份有限公司 | 抗體-藥物結合物之製造方法 |
| US11318212B2 (en) | 2017-08-31 | 2022-05-03 | Daiichi Sankyo Company, Limited | Method for producing antibody-drug conjugate |
| AU2018327171B2 (en) | 2017-08-31 | 2023-03-09 | Daiichi Sankyo Company, Limited | Improved method for producing antibody-drug conjugate |
| SMT202300227T1 (it) | 2018-05-18 | 2023-09-06 | Glycotope Gmbh | Anticorpo anti-muc1 |
| IL280296B2 (en) | 2018-07-27 | 2025-03-01 | Daiichi Sankyo Co Ltd | Drug recognition protein of an antibody-drug conjugate |
| AU2019315177A1 (en) | 2018-07-31 | 2021-02-25 | Daiichi Sankyo Company, Limited | Treatment of metastatic brain tumor by administration of antibody-drug conjugate |
| GB201913079D0 (en) * | 2019-09-11 | 2019-10-23 | Hummingbird Bioscience Holdings Pte Ltd | Treatment and prevention of cancer using her3 antigen-binding molecules |
| WO2021076543A1 (en) | 2019-10-14 | 2021-04-22 | Aro Biotherapeutics Company | Epcam binding fibronectin type iii domains |
| US11781138B2 (en) | 2019-10-14 | 2023-10-10 | Aro Biotherapeutics Company | FN3 domain-siRNA conjugates and uses thereof |
| US11628222B2 (en) | 2019-10-14 | 2023-04-18 | Aro Biotherapeutics Company | CD71 binding fibronectin type III domains |
| AU2022258584A1 (en) | 2021-04-14 | 2023-10-12 | Aro Biotherapeutics Company | Fn3 domain-sirna conjugates and uses thereof |
| TW202304971A (zh) | 2021-04-14 | 2023-02-01 | 美商亞羅生物治療公司 | 結合cd71之纖連蛋白iii型結構域 |
| EP4355787A4 (de) * | 2021-06-15 | 2025-04-30 | Beijing Sinotau Bio-Pharmaceuticals Technology Co., Ltd. | Anti-her3-antikörper, antikörper-wirkstoff-konjugat damit und verwendung davon |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US5183884A (en) * | 1989-12-01 | 1993-02-02 | United States Of America | Dna segment encoding a gene for a receptor related to the epidermal growth factor receptor |
| EP0444961A1 (de) | 1990-03-02 | 1991-09-04 | Bristol-Myers Squibb Company | Her3: Ein neues EGF-Rezeptor Homologes |
| NZ255101A (en) | 1992-07-24 | 1997-08-22 | Cell Genesys Inc | A yeast artificial chromosome (yac) vector containing an hprt minigene expressible in murine stem cells and genetically modified rodent therefor |
| US5804396A (en) * | 1994-10-12 | 1998-09-08 | Sugen, Inc. | Assay for agents active in proliferative disorders |
| CA2246429C (en) | 1996-03-27 | 2007-07-24 | Genentech, Inc. | Erbb3 antibodies |
| US5968511A (en) * | 1996-03-27 | 1999-10-19 | Genentech, Inc. | ErbB3 antibodies |
| AU722178B2 (en) | 1996-07-12 | 2000-07-27 | Genentech Inc. | Chimeric heteromultimer adhesins |
| JP3687900B2 (ja) * | 1998-11-19 | 2005-08-24 | ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー | チロシンキナーゼの不可逆的阻害剤であるn−[4−(3−クロロ−4−フルオロフェニルアミノ)−7−(3−モルホリン−4−イルプロポキシ)キナゾリン−6−イル]アクリルアミド |
| AUPQ105799A0 (en) * | 1999-06-18 | 1999-07-08 | Victor Chang Cardiac Research Institute, The | Cell growth inhibition |
| TR200200472T2 (tr) | 1999-08-27 | 2002-06-21 | Genentech, Inc. | Anti-Erb B2 antikorları ile tedavi için dozajlar |
| US6277640B1 (en) * | 2000-07-31 | 2001-08-21 | Isis Pharmaceuticals, Inc. | Antisense modulation of Her-3 expression |
| EP1228766A1 (de) | 2001-01-31 | 2002-08-07 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | PYK2 Phosphorylierung durch HER3 induziert Tumorinvasion |
| EP1283053A1 (de) | 2001-08-09 | 2003-02-12 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Inhibitore der HER3 Aktivität |
-
2001
- 2001-08-09 EP EP01119260A patent/EP1283053A1/de not_active Withdrawn
-
2002
- 2002-08-09 ES ES02794590T patent/ES2323772T3/es not_active Expired - Lifetime
- 2002-08-09 JP JP2003518606A patent/JP5226926B2/ja not_active Expired - Lifetime
- 2002-08-09 PT PT02794590T patent/PT1414494E/pt unknown
- 2002-08-09 WO PCT/EP2002/008938 patent/WO2003013602A1/en not_active Ceased
- 2002-08-09 AU AU2002333384A patent/AU2002333384B2/en not_active Expired
- 2002-08-09 EP EP02794590A patent/EP1414494B1/de not_active Revoked
- 2002-08-09 AT AT02794590T patent/ATE424219T1/de active
- 2002-08-09 DE DE60231407T patent/DE60231407D1/de not_active Expired - Lifetime
- 2002-08-09 DK DK02794590T patent/DK1414494T3/da active
- 2002-08-09 CN CN2010105512370A patent/CN102078613A/zh active Pending
- 2002-08-09 CN CN028156153A patent/CN1541109B/zh not_active Expired - Lifetime
- 2002-08-09 US US10/486,113 patent/US9011851B2/en active Active
- 2002-08-09 EP EP09002792A patent/EP2067792A2/de not_active Withdrawn
- 2002-08-09 CA CA2456723A patent/CA2456723C/en not_active Expired - Lifetime
-
2009
- 2009-06-03 CY CY20091100593T patent/CY1110322T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1283053A1 (de) | 2003-02-12 |
| ES2323772T3 (es) | 2009-07-24 |
| CN102078613A (zh) | 2011-06-01 |
| US20040197332A1 (en) | 2004-10-07 |
| EP1414494B1 (de) | 2009-03-04 |
| CA2456723A1 (en) | 2003-02-20 |
| DE60231407D1 (de) | 2009-04-16 |
| CN1541109A (zh) | 2004-10-27 |
| JP5226926B2 (ja) | 2013-07-03 |
| CY1110322T1 (el) | 2015-01-14 |
| US9011851B2 (en) | 2015-04-21 |
| EP1414494A1 (de) | 2004-05-06 |
| CN1541109B (zh) | 2013-07-10 |
| EP2067792A2 (de) | 2009-06-10 |
| CA2456723C (en) | 2016-02-09 |
| DK1414494T3 (da) | 2009-07-06 |
| JP2005504044A (ja) | 2005-02-10 |
| PT1414494E (pt) | 2009-06-12 |
| AU2002333384B2 (en) | 2007-11-15 |
| WO2003013602A1 (en) | 2003-02-20 |
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