ATE425159T1 - Substituierte 4-phenylpiperidine zur verwendung als renininhibitoren - Google Patents

Substituierte 4-phenylpiperidine zur verwendung als renininhibitoren

Info

Publication number
ATE425159T1
ATE425159T1 AT07820887T AT07820887T ATE425159T1 AT E425159 T1 ATE425159 T1 AT E425159T1 AT 07820887 T AT07820887 T AT 07820887T AT 07820887 T AT07820887 T AT 07820887T AT E425159 T1 ATE425159 T1 AT E425159T1
Authority
AT
Austria
Prior art keywords
phenylpiperidine
substituted
renin inhibitors
renin
inhibitors
Prior art date
Application number
AT07820887T
Other languages
English (en)
Inventor
Peter Herold
Robert Mah
Stefan Stutz
Vincenzo Tschinke
Aleksandar Stojanovic
Dirk Behnke
Nathalie Jotterand
Stjepan Jelakovic
Original Assignee
Speedel Experimenta Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Speedel Experimenta Ag filed Critical Speedel Experimenta Ag
Application granted granted Critical
Publication of ATE425159T1 publication Critical patent/ATE425159T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
AT07820887T 2006-10-04 2007-10-03 Substituierte 4-phenylpiperidine zur verwendung als renininhibitoren ATE425159T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06121772A EP1911758A1 (de) 2006-10-04 2006-10-04 Phenylpiperidinderivative zur Verwendung als Renin Inhibitoren

Publications (1)

Publication Number Publication Date
ATE425159T1 true ATE425159T1 (de) 2009-03-15

Family

ID=37946086

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07820887T ATE425159T1 (de) 2006-10-04 2007-10-03 Substituierte 4-phenylpiperidine zur verwendung als renininhibitoren

Country Status (17)

Country Link
US (1) US7625893B2 (de)
EP (2) EP1911758A1 (de)
JP (1) JP2009532443A (de)
CN (1) CN101415703B (de)
AR (1) AR063124A1 (de)
AT (1) ATE425159T1 (de)
BR (1) BRPI0716114A2 (de)
CA (1) CA2642455A1 (de)
DE (1) DE602007000679D1 (de)
DK (1) DK1934207T3 (de)
ES (1) ES2322629T3 (de)
IL (1) IL193476A0 (de)
PL (1) PL1934207T3 (de)
PT (1) PT1934207E (de)
SI (1) SI1934207T1 (de)
TW (1) TW200831499A (de)
WO (1) WO2008040764A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0609534A2 (pt) * 2005-03-31 2010-04-13 Speedel Experimenta Ag piperidinas 3,4,5-substituìdas
TW200932241A (en) * 2007-12-05 2009-08-01 Speedel Experimenta Ag Organic compounds
JP5484069B2 (ja) 2007-12-19 2014-05-07 大日本住友製薬株式会社 二環性へテロ環誘導体
BRPI0910991A2 (pt) * 2008-04-02 2016-01-19 Novartis Ag piperidinas substituídas como compostos terapêuticos
KR20120109292A (ko) 2009-06-24 2012-10-08 다이닛본 스미토모 세이야꾸 가부시끼가이샤 Ｎ-치환-시클릭 아미노 유도체

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5194605A (en) * 1989-12-08 1993-03-16 Merck & Co., Inc. Cyclic renin inhibitors containing 2-substituted (3S,4S)-4-amino-5-cyclohexyl-3-hydroxy pentanoic acid, 2-substituted (3S,4S)-5-cyclohexyl-3,4-di-hydroxy pentanoic acid or 2-substituted (4S,5S)-5-amino-6-cyclohexyl-4-hydroxyhexanoic acid or its analogs
CA2031745A1 (en) * 1989-12-08 1991-06-09 William J. Greenlee Cyclic renin inhibitors containing 2-substituted(3s, 4s)-4-amino-5-cyclohexyl-3-hydroxy pentanoic acid, 2-substituted (3s, 4s)-5-cyclohexyl-3,4-dihydroxy-pentanoic acid or 2 -substituted (4s, 5s)-5-amino-6- yclohexyl-4-hydroxyhexanoic acid or its analogs
US6376672B1 (en) * 1999-04-27 2002-04-23 Hoffmann-La Roche Inc. Naphthalenylmethoxypiperidines as renin inhibitors
US20040204455A1 (en) * 2003-04-10 2004-10-14 Cody Wayne Livingston Piperidine derivative rennin inhibitors
AR053406A1 (es) * 2004-07-09 2007-05-09 Speedel Experimenta Ag Derivados de piperidina como inhibidores de renina. composiciones farmaceuticas

Also Published As

Publication number Publication date
SI1934207T1 (sl) 2009-08-31
IL193476A0 (en) 2009-05-04
AR063124A1 (es) 2008-12-30
HK1119678A1 (en) 2009-03-13
CN101415703B (zh) 2012-04-25
DE602007000679D1 (de) 2009-04-23
BRPI0716114A2 (pt) 2013-09-24
EP1934207A1 (de) 2008-06-25
EP1911758A1 (de) 2008-04-16
JP2009532443A (ja) 2009-09-10
TW200831499A (en) 2008-08-01
US7625893B2 (en) 2009-12-01
EP1934207B1 (de) 2009-03-11
CN101415703A (zh) 2009-04-22
ES2322629T3 (es) 2009-06-23
DK1934207T3 (da) 2009-06-02
PT1934207E (pt) 2009-05-21
WO2008040764A1 (en) 2008-04-10
US20090088426A1 (en) 2009-04-02
PL1934207T3 (pl) 2009-10-30
CA2642455A1 (en) 2008-04-10

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