ATE426015T1 - Systeme und verfahren zum screening pharmazeutischer chemikalien - Google Patents

Systeme und verfahren zum screening pharmazeutischer chemikalien

Info

Publication number
ATE426015T1
ATE426015T1 AT02752832T AT02752832T ATE426015T1 AT E426015 T1 ATE426015 T1 AT E426015T1 AT 02752832 T AT02752832 T AT 02752832T AT 02752832 T AT02752832 T AT 02752832T AT E426015 T1 ATE426015 T1 AT E426015T1
Authority
AT
Austria
Prior art keywords
systems
methods
pharmaceutical chemicals
model system
activator
Prior art date
Application number
AT02752832T
Other languages
English (en)
Inventor
Elliot Elson
William Mcconnaughey
Tetsuro Wakatsuki
Original Assignee
Univ St Louis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ St Louis filed Critical Univ St Louis
Application granted granted Critical
Publication of ATE426015T1 publication Critical patent/ATE426015T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5061—Muscle cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N3/00—Investigating strength properties of solid materials by application of mechanical stress
    • G01N3/32—Investigating strength properties of solid materials by application of mechanical stress by applying repeated or pulsating forces
    • G01N3/38—Investigating strength properties of solid materials by application of mechanical stress by applying repeated or pulsating forces generated by electromagnetic means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5064—Endothelial cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082—Supracellular entities, e.g. tissue, organisms
    • G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2203/00—Investigating strength properties of solid materials by application of mechanical stress
    • G01N2203/0001—Type of application of the stress
    • G01N2203/0005—Repeated or cyclic
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2203/00—Investigating strength properties of solid materials by application of mechanical stress
    • G01N2203/0014—Type of force applied
    • G01N2203/0016—Tensile or compressive
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2203/00—Investigating strength properties of solid materials by application of mechanical stress
    • G01N2203/0058—Kind of property studied
    • G01N2203/0069—Fatigue, creep, strain-stress relations or elastic constants
    • G01N2203/0073—Fatigue
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2203/00—Investigating strength properties of solid materials by application of mechanical stress
    • G01N2203/02—Details not specific for a particular testing method
    • G01N2203/026—Specifications of the specimen
    • G01N2203/0262—Shape of the specimen
    • G01N2203/0278—Thin specimens
    • G01N2203/0282—Two dimensional, e.g. tapes, webs, sheets, strips, disks or membranes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • Electromagnetism (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT02752832T 2001-08-14 2002-08-14 Systeme und verfahren zum screening pharmazeutischer chemikalien ATE426015T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31232201P 2001-08-14 2001-08-14

Publications (1)

Publication Number Publication Date
ATE426015T1 true ATE426015T1 (de) 2009-04-15

Family

ID=23210916

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02752832T ATE426015T1 (de) 2001-08-14 2002-08-14 Systeme und verfahren zum screening pharmazeutischer chemikalien

Country Status (8)

Country Link
US (2) US7449306B2 (de)
EP (2) EP1983043A1 (de)
JP (1) JP4638146B2 (de)
AT (1) ATE426015T1 (de)
AU (1) AU2002356043A1 (de)
CA (1) CA2497343C (de)
DE (1) DE60231625D1 (de)
WO (1) WO2003016860A2 (de)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2497343C (en) 2001-08-14 2013-04-02 Washington University In St. Louis Systems and methods for screening pharmaceutical chemicals
US8227240B2 (en) * 2001-08-14 2012-07-24 The Washington University Systems for screening pharmaceutical chemicals
US7348175B2 (en) * 2002-03-15 2008-03-25 St3 Development Corporation Bioreactor with plurality of chambers for conditioning intravascular tissue engineered medical products
US7497864B2 (en) 2003-04-30 2009-03-03 Marctec, Llc. Tissue fastener and methods for using same
EP2578676A1 (de) * 2003-06-20 2013-04-10 Axiogenesis Ag Formgebung zu Gewebe in einem embryonischen Stammzellen (ES) System
US7738682B2 (en) * 2003-10-22 2010-06-15 Medtrain Technologies, Llc Tissue engineered construct analytical imaging system and method of obtaining and analyzing images of tissue engineered constructs
EP1740945B1 (de) 2004-04-07 2018-09-19 Ncardia AG Nichtinvasive, in-vitro-funktionelle gewebetestsysteme
US8318488B1 (en) 2004-05-11 2012-11-27 Axiogenesis Ag Assay for drug discovery based on in vitro differentiated cells
KR100665299B1 (ko) * 2004-06-10 2007-01-04 서울반도체 주식회사 발광물질
WO2006044997A2 (en) * 2004-10-15 2006-04-27 The Trustees Of Columbia University In The City Of New York System and method for localized measurement and imaging of viscosity of tissues
US10687785B2 (en) 2005-05-12 2020-06-23 The Trustees Of Columbia Univeristy In The City Of New York System and method for electromechanical activation of arrhythmias
US8858441B2 (en) * 2005-05-12 2014-10-14 The Trustees Of Columbia University In The City Of New York System and method for electromechanical wave imaging of body structures
US20080025917A1 (en) * 2006-04-10 2008-01-31 Malcolm Whitman Methods for modulating formation and progression of cellulite
US8150128B2 (en) * 2006-08-30 2012-04-03 The Trustees Of Columbia University In The City Of New York Systems and method for composite elastography and wave imaging
JP4931017B2 (ja) * 2008-01-10 2012-05-16 国立大学法人山口大学 細胞への伸展刺激負荷デバイス
WO2011035312A1 (en) 2009-09-21 2011-03-24 The Trustees Of Culumbia University In The City Of New York Systems and methods for opening of a tissue barrier
EP2294177B8 (de) * 2008-06-05 2016-12-21 InvivoSciences, Inc. Dreidimensionale gewebe für testverfahren mit hohem durchsatz
WO2010014977A1 (en) 2008-08-01 2010-02-04 The Trustees Of Columbia University In The City Of New York Systems and methods for matching and imaging tissue characteristics
AU2009282480B2 (en) 2008-08-11 2015-05-07 Children's Medical Center Corporation Halofuginone analogs for inhibition of tRNA synthetases and uses thereof
WO2010030819A1 (en) 2008-09-10 2010-03-18 The Trustees Of Columbia University In The City Of New York Systems and methods for opening a tissue
JP2015037381A (ja) * 2009-03-18 2015-02-26 株式会社豊田中央研究所 筋細胞の出力装置及び筋細胞の出力評価方法
US20130184318A1 (en) * 2010-04-30 2013-07-18 The Regents Of The University Of California Modulating compliance of trabecular meshwork
JP5549547B2 (ja) * 2010-11-04 2014-07-16 株式会社豊田中央研究所 筋細胞の出力装置及び筋細胞の出力評価方法
US9320491B2 (en) 2011-04-18 2016-04-26 The Trustees Of Columbia University In The City Of New York Ultrasound devices methods and systems
WO2012162664A1 (en) 2011-05-26 2012-11-29 The Trustees Of Columbia University In The City Of New York Systems and methods for opening of a tissue barrier in primates
WO2012170490A2 (en) 2011-06-06 2012-12-13 Invivosciences, Llc Engineered cardiac tissues and methods of using them
US10155742B2 (en) 2012-01-13 2018-12-18 President And Fellows Of Harvard College Halofuginol derivatives and their use in cosmetic and pharmaceutical compositions
WO2014059170A1 (en) 2012-10-10 2014-04-17 The Trustees Of Columbia University In The City Of New York Systems and methods for mechanical mapping of cardiac rhythm
US9247921B2 (en) 2013-06-07 2016-02-02 The Trustees Of Columbia University In The City Of New York Systems and methods of high frame rate streaming for treatment monitoring
US10322178B2 (en) 2013-08-09 2019-06-18 The Trustees Of Columbia University In The City Of New York Systems and methods for targeted drug delivery
US10028723B2 (en) 2013-09-03 2018-07-24 The Trustees Of Columbia University In The City Of New York Systems and methods for real-time, transcranial monitoring of blood-brain barrier opening
KR102343744B1 (ko) * 2013-10-30 2021-12-24 밀리차 라디식 3차원 조직 배양을 위한 장치 및 방법
US20180273904A1 (en) * 2015-10-02 2018-09-27 Wake Forest University Health Sciences Spontaneously beating cardiac organoid constructs and integrated body-on-chip apparatus containing the same
DE102016110328B3 (de) * 2016-06-03 2017-09-07 Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin Lochplatte
FR3064359B1 (fr) * 2017-03-21 2021-04-16 Centre Nat Rech Scient Dispositif pour la caracterisation mecanique d'un element d'interet par exemple un ovocyte
US12411128B2 (en) * 2017-06-26 2025-09-09 The Regents Of The University Of California Methods and apparatuses for prediction of mechanism of activity of compounds
US12038432B2 (en) 2018-02-02 2024-07-16 Wake Forest University Health Sciences Organoids related to immunotherapy and methods of preparing and using the same
EP3801525A4 (de) 2018-06-08 2022-03-23 The General Hospital Corporation Inhibitoren der prolyl-trna-synthetase
WO2021145038A1 (ja) * 2020-01-17 2021-07-22 ロート製薬株式会社 組織形態・組織機能制御剤の評価／スクリーニング方法

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US526357A (en) * 1894-09-18 Antirust-ware
US4593042A (en) * 1985-10-18 1986-06-03 G. D. Searle & Co. Bicyclo-substituted phenylacetonitrile derivatives
US4705785A (en) 1986-04-09 1987-11-10 Ortho Pharmaceutical Corporation Substituted thiacycloalkeno (3,2-b) pyridines and pharmaceutical compositions and method of use
US4839280A (en) * 1987-05-04 1989-06-13 Banes Albert J Apparatus for applying stress to cell cultures
US5038795A (en) * 1987-08-05 1991-08-13 Roush Elsie S Muscle tonometer apparatus and method
US5464853A (en) 1993-05-20 1995-11-07 Immunopharmaceutics, Inc. N-(5-isoxazolyl)biphenylsulfonamides, N-(3-isoxazolyl)biphenylsulfonamides and derivatives thereof that modulate the activity of endothelin
US5122470A (en) * 1988-07-05 1992-06-16 Banes Albert J Floating cell culture device and method
US4940853A (en) * 1988-07-22 1990-07-10 Vandenburgh Herman H Method for growing tissue specimens in vitro
US4940856A (en) * 1989-06-26 1990-07-10 Burndy Corporation Electrical connector
US5326357A (en) * 1992-03-18 1994-07-05 Mount Sinai Hospital Corporation Reconstituted cartridge tissue
US5486457A (en) * 1993-08-25 1996-01-23 Children's Medical Center Corporation Method and system for measurement of mechanical properties of molecules and cells
US5571083A (en) * 1994-02-18 1996-11-05 Lemelson; Jerome H. Method and system for cell transplantation
DE19500498C2 (de) 1995-01-10 1997-05-07 Thomas Dr Med Eschenhagen Matrixkörper für die Messung isometrischer Kraftparameter von Zellgewebe, Verfahren zum Herstellen des Matrixkörpers, Set für dieses Verfahren und Verwendung des Matrixkörpers zum Kultivieren von Kardiomyozyten
WO1997011641A1 (en) 1995-09-27 1997-04-03 Artann Laboratories Measuring anisotropic mechanical properties of tissue
US5665391A (en) * 1995-10-12 1997-09-09 Spectral Diagnostics Inc. Cultured, full-thickness integument substitutes based on three-dimensional matrix membranes
US20060105357A1 (en) * 1998-02-18 2006-05-18 Myomics, Inc. Tissue sensor and uses thereof
DE69903800T2 (de) 1998-03-18 2003-10-02 Massachusetts Institute Of Technology, Cambridge Vaskularisierte perfundierte anordnungen für mikrogewebe und mikroorgane
WO2001000856A1 (en) 1999-06-25 2001-01-04 Genetronics, Inc. High efficiency transfection based on low electric field strength, long pulse length
CA2306275C (en) * 1999-04-23 2009-11-03 Bio Syntech Canada Inc. Universal mechanical testing device
DE10003521A1 (de) 2000-01-27 2001-08-09 Medigene Ag Vorrichtung zum Herstellen eines dreidimensionalen Matrixkörpers, Multi-Well-Platte, Lösung zum Kultivieren von Säugerkardiomyocyten, Verfahren zum Kultivieren einer Zellkultur, Vorrichtung für die Messung isometrischer Kraftparameter von Zellkulturen sowie Verfahren zum meßbaren Verfolgen von Kontraktionen eines in eine Trägersubstanz eingelagerten Zellgewebes
US8227240B2 (en) 2001-08-14 2012-07-24 The Washington University Systems for screening pharmaceutical chemicals
CA2497343C (en) 2001-08-14 2013-04-02 Washington University In St. Louis Systems and methods for screening pharmaceutical chemicals

Also Published As

Publication number Publication date
JP4638146B2 (ja) 2011-02-23
EP1425385B1 (de) 2009-03-18
JP2005523417A (ja) 2005-08-04
CA2497343A1 (en) 2003-02-27
EP1425385A2 (de) 2004-06-09
AU2002356043A1 (en) 2003-03-03
WO2003016860A2 (en) 2003-02-27
CA2497343C (en) 2013-04-02
EP1425385A4 (de) 2005-04-06
WO2003016860A3 (en) 2003-06-12
DE60231625D1 (de) 2009-04-30
US20030064358A1 (en) 2003-04-03
US7449306B2 (en) 2008-11-11
US20090068701A1 (en) 2009-03-12
US8071381B2 (en) 2011-12-06
EP1983043A1 (de) 2008-10-22

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