ATE427653T1 - Stabilisierung der milch transgener tieren - Google Patents

Stabilisierung der milch transgener tieren

Info

Publication number: ATE427653T1
Authority: AT; Austria
Prior art keywords: milk; transgenic animals; stabilization; relates; antitrypsin
Prior art date: 1998-11-19

Application number

AT99972491T

Other languages

English (en)

Inventor

Ian Cottingham

Graham Mccreath

Original Assignee

Pharming Intellectual Pty Bv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-11-19

Filing date

1999-11-19

Publication date

2009-04-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26314697&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE427653(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1998-11-19 Priority claimed from GBGB9825374.3A external-priority patent/GB9825374D0/en

1999-11-19 Application filed by Pharming Intellectual Pty Bv filed Critical Pharming Intellectual Pty Bv

2009-04-15 Application granted granted Critical

2009-04-15 Publication of ATE427653T1 publication Critical patent/ATE427653T1/de

Links

241001465754 Metazoa Species 0.000 title abstract 4
239000008267 milk Substances 0.000 title abstract 4
210000004080 milk Anatomy 0.000 title abstract 4
235000013336 milk Nutrition 0.000 title abstract 4
230000009261 transgenic effect Effects 0.000 title abstract 4
230000006641 stabilisation Effects 0.000 title abstract 2
238000011105 stabilization Methods 0.000 title 1
102000008946 Fibrinogen Human genes 0.000 abstract 1
108010049003 Fibrinogen Proteins 0.000 abstract 1
101710187074 Serine proteinase inhibitor Proteins 0.000 abstract 1
102000015395 alpha 1-Antitrypsin Human genes 0.000 abstract 1
108010050122 alpha 1-Antitrypsin Proteins 0.000 abstract 1
229940024142 alpha 1-antitrypsin Drugs 0.000 abstract 1
230000004186 co-expression Effects 0.000 abstract 1
229940012952 fibrinogen Drugs 0.000 abstract 1
102000004169 proteins and genes Human genes 0.000 abstract 1
108090000623 proteins and genes Proteins 0.000 abstract 1
239000003001 serine protease inhibitor Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/75—Fibrinogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
- C07K14/8121—Serpins
- C07K14/8125—Alpha-1-antitrypsin
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/103—Ovine
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/01—Animal expressing industrially exogenous proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Biotechnology (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Medicinal Chemistry (AREA)
General Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Environmental Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Veterinary Medicine (AREA)
Gastroenterology & Hepatology (AREA)
Animal Behavior & Ethology (AREA)
Toxicology (AREA)
Microbiology (AREA)
Animal Husbandry (AREA)
Biodiversity & Conservation Biology (AREA)
Plant Pathology (AREA)
Hematology (AREA)
Physics & Mathematics (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Enzymes And Modification Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Dairy Products (AREA)
Feed For Specific Animals (AREA)
Fodder In General (AREA)

AT99972491T 1998-11-19 1999-11-19 Stabilisierung der milch transgener tieren ATE427653T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9825374.3A GB9825374D0 (en)	1998-11-19	1998-11-19	Method
US12854699P	1999-04-09	1999-04-09

Publications (1)

Publication Number	Publication Date
ATE427653T1 true ATE427653T1 (de)	2009-04-15

Family

ID=26314697

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99972491T ATE427653T1 (de)	1998-11-19	1999-11-19	Stabilisierung der milch transgener tieren

Country Status (8)

Country	Link
EP (1)	EP1130961B1 (de)
JP (1)	JP2011167196A (de)
AT (1)	ATE427653T1 (de)
AU (1)	AU765315B2 (de)
CA (1)	CA2351943A1 (de)
DE (1)	DE69940700D1 (de)
NZ (1)	NZ511299A (de)
WO (1)	WO2000030436A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2547337A1 (de)	2010-03-17	2013-01-23	Pharming Intellectual Property B.V.	Verwendung von antikoagulanzien bei der herstellung von rekombinanten proteinen in der milch von transgenen tieren
EP2793936A4 (de) *	2011-12-19	2015-05-27	Lfb Usa Inc	Rekombinantes menschliches alpha-1-antitrypsin zur behandlung von entzündungskrankheiten
EP3594230A1 (de)	2013-02-13	2020-01-15	Laboratoire Français du Fractionnement et des Biotechnologies	In hohem masse galactosylierte anti-tnf-alpha-antikörper und verwendungen davon
US10034921B2 (en)	2013-02-13	2018-07-31	Laboratoire Français Du Fractionnement Et Des Biotechnologies	Proteins with modified glycosylation and methods of production thereof
EP3088513B1 (de) *	2013-12-27	2019-02-06	Japan Blood Products Organization	Hochproduktionslinie für rekombinantes fibrinogen und verfahren zur herstellung davon
FR3038517B1 (fr)	2015-07-06	2020-02-28	Laboratoire Francais Du Fractionnement Et Des Biotechnologies	Utilisation de fragments fc modifies en immunotherapie
CN112666112A (zh) *	2020-10-01	2021-04-16	华中农业大学	骆驼奶与马奶的批量鉴别模型和方法
CN112666114A (zh) *	2020-10-01	2021-04-16	华中农业大学	利用光谱识别水牛奶与马奶的方法
CN112666113A (zh) *	2020-10-01	2021-04-16	华中农业大学	山羊奶和马奶的快速鉴别方法
CN112525850A (zh) *	2020-10-01	2021-03-19	华中农业大学	奶牛奶、马奶、骆驼奶、山羊奶和水牛奶的光谱指纹识别方法
CN112666111A (zh) *	2020-10-01	2021-04-16	华中农业大学	奶牛奶与马奶的快速鉴别方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9028062D0 (en) *	1990-12-24	1991-02-13	Agricultural & Food Res	Production of transgenic animals
US5272074A (en)	1992-04-23	1993-12-21	Mcmaster University	Fibrin coated polymer surfaces
WO1994019935A1 (en) *	1993-03-09	1994-09-15	Genzyme Corporation	Isolation of components of interest from milk
ATE374525T1 (de) *	1994-02-18	2007-10-15	American Nat Red Cross	Transgenes fibrinogen
US5639940A (en)	1994-03-03	1997-06-17	Pharmaceutical Proteins Ltd.	Production of fibrinogen in transgenic animals
US5880327A (en) *	1994-09-21	1999-03-09	American National Red Cross	Transgenic mammals expressing human coagulation factor VIII
GB9517780D0 (en)	1995-08-31	1995-11-01	Roslin Inst Edinburgh	Biological manipulation
GB9517779D0 (en)	1995-08-31	1995-11-01	Roslin Inst Edinburgh	Biological manipulation
SE9601091L (sv) *	1996-03-21	1997-09-22	Joyce Carlson	Användning av en proteinsubstans för bindning av steroid-liknande molekyler

1999
- 1999-11-19 NZ NZ511299A patent/NZ511299A/xx not_active IP Right Cessation
- 1999-11-19 WO PCT/GB1999/003868 patent/WO2000030436A1/en not_active Ceased
- 1999-11-19 AT AT99972491T patent/ATE427653T1/de not_active IP Right Cessation
- 1999-11-19 DE DE69940700T patent/DE69940700D1/de not_active Expired - Lifetime
- 1999-11-19 CA CA002351943A patent/CA2351943A1/en not_active Abandoned
- 1999-11-19 AU AU13956/00A patent/AU765315B2/en not_active Ceased
- 1999-11-19 EP EP99972491A patent/EP1130961B1/de not_active Expired - Lifetime
2011
- 2011-03-18 JP JP2011061142A patent/JP2011167196A/ja active Pending

Also Published As

Publication number	Publication date
NZ511299A (en)	2003-02-28
EP1130961B1 (de)	2009-04-08
EP1130961A1 (de)	2001-09-12
AU1395600A (en)	2000-06-13
CA2351943A1 (en)	2000-06-02
JP2011167196A (ja)	2011-09-01
WO2000030436A1 (en)	2000-06-02
AU765315B2 (en)	2003-09-18
DE69940700D1 (de)	2009-05-20

Legal Events

Date	Code	Title	Description
2009-10-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE442843T1 (de)	2009-10-15	Verwendung von c-terminal modifizierter oxamyl dipeptide als inhibitoren von der ice/ced-3 familie von cystein proteasen
ATE193304T1 (de)	2000-06-15	Inhibitoren der menschlichen neutrophilenelastase
CY1112267T1 (el)	2015-12-09	Νεα πεπτιδια ως αναστολεις πρωτεασης ns3-σερινης του ιου ηπατιτιδας c
ATE427653T1 (de)	2009-04-15	Stabilisierung der milch transgener tieren
WO2002048116A3 (en)	2007-10-25	Inhibitors of hepatitis c virus ns3 protease
NO942064L (no)	1994-12-05	yminhibitorer
TR199901191T2 (xx)	1999-12-21	Benzamidoaldehitlerin sistein proteaz� inhibit�r� olarak kullan�m�.
DK1202743T3 (da)	2005-02-14	Farmaceutiske og kosmetiske sammensætninger omfattende serinproteaser fra torsk og deres farmaceutiske og kosmetiske anvendelse
NO20004696L (no)	2000-09-20	Kinoloner som serinproteaseinhibitorer
DK0462207T3 (da)	2001-06-18	t-Pa mutanter resistente mod deres respektive inhibitorer
DE50002836D1 (de)	2003-08-14	Substituierte anilinverbindungen
DK1392291T3 (da)	2007-10-08	Tripeptidylpeptidaseinhibitorer
ATE170868T1 (de)	1998-09-15	Peptid-phosphinyloxymethyl-ketonen als inhibitoren von interleukin-1 beta- konvertierenden enzymen
NO20005261L (no)	2000-10-19	Nye heterocyklisk substituerte amider med cystein-protease- inhiberende virkning
ATE232873T1 (de)	2003-03-15	Phosphonsaürederivate als ptp-1b-inhibitoren
TR200002932T2 (tr)	2001-01-22	Azabisayklik 5HT1 Alıcı liganolları
ATE240299T1 (de)	2003-05-15	Diester prodrugs von decahydroischinoline-3- carbonsäure
DK1097233T3 (da)	2009-03-23	Promotor for vækstdifferentieringsfaktor og anvendelser deraf
WO1998020034A3 (en)	1998-08-06	Novel serine protease inhibitor nucleic acid molecules, proteins and uses thereof
MY137258A (en)	2009-01-30	Bacterial insecticidal protein
WO2003097593A3 (en)	2004-07-08	Protease inhibitors
SE0303120D0 (sv)	2003-11-25	Novel alkaline protease
WO2005034838A3 (en)	2005-07-28	Protease inhibitors
WO2002010124A3 (en)	2003-05-01	Salt forms of an hiv protease inhibitor
DE69921505D1 (de)	2004-12-02	Serinprotease-inhibitor