ATE427653T1 - Stabilisierung der milch transgener tieren - Google Patents

Stabilisierung der milch transgener tieren

Info

Publication number
ATE427653T1
ATE427653T1 AT99972491T AT99972491T ATE427653T1 AT E427653 T1 ATE427653 T1 AT E427653T1 AT 99972491 T AT99972491 T AT 99972491T AT 99972491 T AT99972491 T AT 99972491T AT E427653 T1 ATE427653 T1 AT E427653T1
Authority
AT
Austria
Prior art keywords
milk
transgenic animals
stabilization
relates
antitrypsin
Prior art date
Application number
AT99972491T
Other languages
English (en)
Inventor
Ian Cottingham
Graham Mccreath
Original Assignee
Pharming Intellectual Pty Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26314697&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE427653(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9825374.3A external-priority patent/GB9825374D0/en
Application filed by Pharming Intellectual Pty Bv filed Critical Pharming Intellectual Pty Bv
Application granted granted Critical
Publication of ATE427653T1 publication Critical patent/ATE427653T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
    • A01K67/0275Genetically modified vertebrates, e.g. transgenic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/75Fibrinogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/8107Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121Serpins
    • C07K14/8125Alpha-1-antitrypsin
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/10Mammal
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/10Mammal
    • A01K2227/103Ovine
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00Animals characterised by purpose
    • A01K2267/01Animal expressing industrially exogenous proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Dairy Products (AREA)
  • Fodder In General (AREA)
  • Feed For Specific Animals (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT99972491T 1998-11-19 1999-11-19 Stabilisierung der milch transgener tieren ATE427653T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9825374.3A GB9825374D0 (en) 1998-11-19 1998-11-19 Method
US12854699P 1999-04-09 1999-04-09

Publications (1)

Publication Number Publication Date
ATE427653T1 true ATE427653T1 (de) 2009-04-15

Family

ID=26314697

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99972491T ATE427653T1 (de) 1998-11-19 1999-11-19 Stabilisierung der milch transgener tieren

Country Status (8)

Country Link
EP (1) EP1130961B1 (de)
JP (1) JP2011167196A (de)
AT (1) ATE427653T1 (de)
AU (1) AU765315B2 (de)
CA (1) CA2351943A1 (de)
DE (1) DE69940700D1 (de)
NZ (1) NZ511299A (de)
WO (1) WO2000030436A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011115479A1 (en) * 2010-03-17 2011-09-22 Pharming Intellectual Property Bv Use of anticoagulants in the production of recombinant proteins in the milk of transgenic animals
CN104302312A (zh) * 2011-12-19 2015-01-21 Lfb美国股份有限公司 用于炎性病症治疗的重组人α-1-抗胰蛋白酶
BR112015019348A2 (pt) 2013-02-13 2017-08-22 Lab Francais Du Fractionnement Métodos para produção de proteína com glicosilação modificada e com sialilação aumentada, para aumentar a atividade de sialil transferase na glândula mamária e para produzir sialil transferase, proteína com glicosilação modificada ou proteína com sialilação aumentada, composição, sialil transferase, mamífero transgênico, e, célula epitelial mamária
KR20160002713A (ko) 2013-02-13 2016-01-08 라보라토이레 프란카이즈 듀 프락티온네먼트 에트 데스 바이오테크놀로지스 고도로 갈락토실화된 항-tnf-알파 항체 및 이의 용도
WO2015099124A1 (ja) 2013-12-27 2015-07-02 一般社団法人 日本血液製剤機構 組換えフィブリノゲン高産生株及びその製造方法
FR3038517B1 (fr) 2015-07-06 2020-02-28 Laboratoire Francais Du Fractionnement Et Des Biotechnologies Utilisation de fragments fc modifies en immunotherapie
CN112666113A (zh) * 2020-10-01 2021-04-16 华中农业大学 山羊奶和马奶的快速鉴别方法
CN112666111A (zh) * 2020-10-01 2021-04-16 华中农业大学 奶牛奶与马奶的快速鉴别方法
CN112525850A (zh) * 2020-10-01 2021-03-19 华中农业大学 奶牛奶、马奶、骆驼奶、山羊奶和水牛奶的光谱指纹识别方法
CN112666112A (zh) * 2020-10-01 2021-04-16 华中农业大学 骆驼奶与马奶的批量鉴别模型和方法
CN112666114A (zh) * 2020-10-01 2021-04-16 华中农业大学 利用光谱识别水牛奶与马奶的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9028062D0 (en) * 1990-12-24 1991-02-13 Agricultural & Food Res Production of transgenic animals
US5272074A (en) 1992-04-23 1993-12-21 Mcmaster University Fibrin coated polymer surfaces
ES2146648T3 (es) * 1993-03-09 2000-08-16 Genzyme Corp Procedimiento de aislamiento de proteinas de la leche.
ATE374525T1 (de) * 1994-02-18 2007-10-15 American Nat Red Cross Transgenes fibrinogen
US5639940A (en) 1994-03-03 1997-06-17 Pharmaceutical Proteins Ltd. Production of fibrinogen in transgenic animals
US5880327A (en) * 1994-09-21 1999-03-09 American National Red Cross Transgenic mammals expressing human coagulation factor VIII
GB9517780D0 (en) 1995-08-31 1995-11-01 Roslin Inst Edinburgh Biological manipulation
GB9517779D0 (en) 1995-08-31 1995-11-01 Roslin Inst Edinburgh Biological manipulation
SE9601091L (sv) * 1996-03-21 1997-09-22 Joyce Carlson Användning av en proteinsubstans för bindning av steroid-liknande molekyler

Also Published As

Publication number Publication date
DE69940700D1 (de) 2009-05-20
EP1130961B1 (de) 2009-04-08
AU1395600A (en) 2000-06-13
WO2000030436A1 (en) 2000-06-02
JP2011167196A (ja) 2011-09-01
NZ511299A (en) 2003-02-28
AU765315B2 (en) 2003-09-18
CA2351943A1 (en) 2000-06-02
EP1130961A1 (de) 2001-09-12

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