NO20061395L - Nye pyridinderivater - Google Patents

Nye pyridinderivater

Info

Publication number: NO20061395L
Authority: NO; Norway
Prior art keywords: pyridine derivatives; compounds; new pyridine; preparation; relates
Prior art date: 2003-09-26

Application number

NO20061395A

Other languages

English (en)

Norwegian (no)

Inventor

Thomas Weller

Martine Clozel

Boris Mathys

Daniel Bur

Claus Mueller

Michael Scherz

Joerg Velker

Original Assignee

Actelion Pharmaceuticals Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-09-26

Filing date

2006-03-27

Publication date

2006-06-22

2006-03-27 Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd

2006-06-22 Publication of NO20061395L publication Critical patent/NO20061395L/no

Links

150000003222 pyridines Chemical class 0.000 title abstract 2
150000001875 compounds Chemical class 0.000 abstract 3
238000002360 preparation method Methods 0.000 abstract 2
102000050488 Urotensin II Human genes 0.000 abstract 1
108010018369 Urotensin II Proteins 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
239000005557 antagonist Substances 0.000 abstract 1
239000003112 inhibitor Substances 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
230000002644 neurohormonal effect Effects 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
239000000825 pharmaceutical preparation Substances 0.000 abstract 1
HFNHAPQMXICKCF-USJMABIRSA-N urotensin-ii Chemical compound N([C@@H](CC(O)=O)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H](CC=2C=CC(O)=CC=2)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC=2C3=CC=CC=C3NC=2)NC(=O)[C@H](CC=2C=CC=CC=2)NC1=O)C(=O)N[C@@H](C(C)C)C(O)=O)C(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@@H](N)CCC(O)=O)[C@@H](C)O HFNHAPQMXICKCF-USJMABIRSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Diabetes (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Hematology (AREA)
Pain & Pain Management (AREA)
Pulmonology (AREA)
Psychiatry (AREA)
Endocrinology (AREA)
Ophthalmology & Optometry (AREA)
Urology & Nephrology (AREA)
Hospice & Palliative Care (AREA)
Physical Education & Sports Medicine (AREA)
Addiction (AREA)
Oncology (AREA)
Vascular Medicine (AREA)
Obesity (AREA)
Gynecology & Obstetrics (AREA)
Reproductive Health (AREA)
Orthopedic Medicine & Surgery (AREA)
Emergency Medicine (AREA)
Gastroenterology & Hepatology (AREA)
Communicable Diseases (AREA)

NO20061395A 2003-09-26 2006-03-27 Nye pyridinderivater NO20061395L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP0310746		2003-09-26
PCT/EP2004/010559 WO2005030209A1 (en)	2003-09-26	2004-09-21	Pyridine derivatives and use thereof as urotensin ii antagonists

Publications (1)

Publication Number	Publication Date
NO20061395L true NO20061395L (no)	2006-06-22

Family

ID=34384524

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20061395A NO20061395L (no)	2003-09-26	2006-03-27	Nye pyridinderivater

Country Status (18)

Country	Link
US (1)	US7750161B2 (de)
EP (1)	EP1670470B1 (de)
JP (1)	JP4851328B2 (de)
KR (1)	KR20070014108A (de)
CN (1)	CN1856305B (de)
AR (1)	AR045949A1 (de)
AT (1)	ATE427748T1 (de)
AU (1)	AU2004275488A1 (de)
BR (1)	BRPI0414777A (de)
CA (1)	CA2540196C (de)
DE (1)	DE602004020486D1 (de)
IL (1)	IL174497A0 (de)
MX (1)	MXPA06003264A (de)
NO (1)	NO20061395L (de)
RU (1)	RU2006113948A (de)
TW (1)	TW200526630A (de)
WO (1)	WO2005030209A1 (de)
ZA (1)	ZA200602442B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20050026844A1 (en)	2003-04-03	2005-02-03	Regents Of The University Of California	Inhibitors for the soluble epoxide hydrolase
DE10358539A1 (de) *	2003-12-15	2005-07-07	Merck Patent Gmbh	Carbonsäureamidderivate
EP1765311A4 (de)	2004-03-16	2009-04-29	Univ California	Verringerung von nephropathie mit hemmern der löslichen epoxid-hydrolase und von epoxyeicosanoiden
MX2007004293A (es) *	2004-10-12	2007-06-18	Actelion Pharmaceuticals Ltd	1[2-(4-bencil-4-hidroxi-piperidin-1-il)-etil]-3-(2-metil-quinolin -4-il)-urea como la sal de sulfato cristalina.
TW200630337A (en)	2004-10-14	2006-09-01	Euro Celtique Sa	Piperidinyl compounds and the use thereof
AU2005295167B2 (en)	2004-10-20	2012-05-10	The Regents Of The University Of California	Improved inhibitors for the soluble epoxide hydrolase
SE0403084D0 (sv)	2004-12-17	2004-12-17	Astrazeneca Ab	Chemical process
US20070043104A1 (en) *	2005-06-10	2007-02-22	Luthman Ingrid K	UII-modulating compounds and their use
TW200808723A (en)	2006-03-13	2008-02-16	Univ California	Conformationally restricted urea inhibitors of soluble epoxide hydrolase
WO2007110449A1 (en) *	2006-03-29	2007-10-04	Euro-Celtique S.A.	Benzenesulfonamide compounds and their use
TW200812963A (en) *	2006-04-13	2008-03-16	Euro Celtique Sa	Benzenesulfonamide compounds and the use thereof
WO2007118853A1 (en) *	2006-04-13	2007-10-25	Euro-Celtique S.A.	Benzenesulfonamide compounds and their use as blockers of calcium channels
CA2669561A1 (en) *	2006-12-22	2008-07-03	Actelion Pharmaceuticals Ltd	5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine derivatives
US8399486B2 (en)	2007-04-09	2013-03-19	Purdue Pharma L.P.	Benzenesulfonyl compounds and the use thereof
US8765736B2 (en) *	2007-09-28	2014-07-01	Purdue Pharma L.P.	Benzenesulfonamide compounds and the use thereof
BRPI0820701A2 (pt)	2007-12-11	2015-06-16	Cytopathfinder Inc	Composto de carboxamida e seu uso como agonistas do receptor de quimiocina
US9296693B2 (en)	2010-01-29	2016-03-29	The Regents Of The University Of California	Acyl piperidine inhibitors of soluble epoxide hydrolase

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FI97540C (fi)	1989-11-06	1997-01-10	Sanofi Sa	Menetelmä terapeuttisesti käyttökelpoisten, aromaattisesti substituoitujen piperidiini- ja piperatsiinijohdannaisten valmistamiseksi
US6159700A (en)	1997-01-27	2000-12-12	Smithkline Beecham Corporation	Method of finding agonist and antagonist to human and rat GPR14
AUPP003197A0 (en)	1997-09-03	1997-11-20	Fujisawa Pharmaceutical Co., Ltd.	New heterocyclic compounds
US6444686B1 (en) *	1998-12-18	2002-09-03	Brsitol-Myers Squibb Pharma Company	N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
US6331541B1 (en) *	1998-12-18	2001-12-18	Soo S. Ko	N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
WO2001009088A1 (en)	1999-07-28	2001-02-08	Kirin Beer Kabushiki Kaisha	Urea derivatives as inhibitors of ccr-3 receptor
JP2003518057A (ja)	1999-12-21	2003-06-03	スミスクライン・ビーチャム・コーポレイション	ウロテンシン−ｉｉ受容体アンタゴニスト
WO2001045711A1 (en)	1999-12-21	2001-06-28	Smithkline Beecham Corporation	Urotensin-ii receptor antagonists
EP1246619B1 (de)	1999-12-21	2004-10-20	Smithkline Beecham Corporation	Urotensin-ii rezeptorantagonisten
EP1262195A4 (de)	2000-03-07	2003-05-21	Takeda Chemical Industries Ltd	Vasoaktieve agentia
EP1363881A2 (de) *	2000-06-21	2003-11-26	Bristol-Myers Squibb Pharma Company	N-ureidoalkyl-piperidine zur verwendung als chemokin-receptor-modulatoren
US7091247B2 (en)	2000-06-28	2006-08-15	Takeda Pharmaceutical Company Limited	Biphenyl compound
US20040063699A1 (en)	2000-07-04	2004-04-01	Naoki Tarui	Gpr14 antagonist
US20040039017A1 (en)	2000-12-11	2004-02-26	Dashyant Dhanak	Urotensin-II receptor antagonists
JP2004515507A (ja)	2000-12-11	2004-05-27	スミスクライン・ビーチャム・コーポレイション	ウロテンシン−ｉｉ受容体アンタゴニスト
JP2004524295A (ja)	2001-01-26	2004-08-12	スミスクライン・ビーチャム・コーポレイション	ウロテンシン−ｉｉ受容体アンタゴニスト
DE60205234T2 (de) *	2001-03-27	2006-05-24	Actelion Pharmaceuticals Ltd.	1,2,3,4-tetrahydroisochinolin-derivate als urotensin ii rezeptor-antagonisten
US20040142923A1 (en)	2001-03-29	2004-07-22	Dashyant Dhanak	Pyrrolidine sulfonamides
JP2004525156A (ja)	2001-03-29	2004-08-19	スミスクライン・ビーチャム・コーポレイション	ピロリジンスルホンアミド
WO2002079155A1 (en)	2001-03-29	2002-10-10	Smithkline Beecham Corporation	Pyrrolidine sulfonamides
WO2002078707A1 (en)	2001-03-29	2002-10-10	Smithkline Beecham Corporation	Pyrrolidine sulfonamides
JP2004529168A (ja)	2001-05-07	2004-09-24	スミスクライン・ビーチャム・コーポレイション	スルホンアミド
AU2002256497A1 (en)	2001-05-07	2002-11-18	Smithkline Beecham Corporation	Sulfonamides
AR033879A1 (es)	2001-05-07	2004-01-07	Smithkline Beecham Corp	Compuesto sulfonamida, composicion farmaceutica que lo comprende, su uso para preparar dicha composicion y procedimiento para la obtencion de dicho compuesto
EP1399137A4 (de)	2001-05-07	2005-12-14	Smithkline Beecham Corp	Sulfonamide
JP2004529164A (ja)	2001-05-07	2004-09-24	スミスクライン・ビーチャム・コーポレイション	スルホンアミド
EP1385841A4 (de)	2001-05-07	2005-03-02	Smithkline Beecham Corp	Sulfonamide
DK1499607T3 (da) *	2001-12-04	2006-04-18	Actelion Pharmaceuticals Ltd	4-(piperidyl- og pyrrolidyl-alkyl-ureido)-quinoliner som urotensin II-receptorantagonister
RU2005111589A (ru)	2002-09-17	2006-01-20	Актелион Фармасьютиклз Лтд. (Ch)	Производные 1-пиридин-4-илмочевины
WO2004043368A2 (en)	2002-11-06	2004-05-27	Smithkline Beecham Corporation	Sulfonamides
WO2004043917A1 (en)	2002-11-06	2004-05-27	Smithkline Beecham Corporation	Sulfonamides
AU2003291303A1 (en)	2002-11-06	2004-06-03	Smithkline Beecham Corporation	Sulfonamides
WO2004043369A2 (en)	2002-11-06	2004-05-27	Smithkline Beecham Corporation	Sulfonamides
AR041885A1 (es)	2002-11-06	2005-06-01	Smithkline Beecham Corp	Compuesto de sulfonamida, composicion farmaceutica que lo comprende y su uso para preparar dicha composicion
EP2415760A3 (de)	2003-02-20	2012-02-22	Encysive Pharmaceuticals, Inc.	CCR-9-Antagonisten
JP2006525273A (ja) *	2003-05-07	2006-11-09	アクテリオン　ファマシューティカルズ　リミテッド	新規なピペラジン誘導体

2004
- 2004-09-21 BR BRPI0414777-4A patent/BRPI0414777A/pt not_active Application Discontinuation
- 2004-09-21 CN CN2004800277254A patent/CN1856305B/zh not_active Expired - Fee Related
- 2004-09-21 CA CA2540196A patent/CA2540196C/en not_active Expired - Fee Related
- 2004-09-21 AT AT04765436T patent/ATE427748T1/de not_active IP Right Cessation
- 2004-09-21 DE DE602004020486T patent/DE602004020486D1/de not_active Expired - Lifetime
- 2004-09-21 AU AU2004275488A patent/AU2004275488A1/en not_active Abandoned
- 2004-09-21 WO PCT/EP2004/010559 patent/WO2005030209A1/en not_active Ceased
- 2004-09-21 EP EP04765436A patent/EP1670470B1/de not_active Expired - Lifetime
- 2004-09-21 JP JP2006527332A patent/JP4851328B2/ja not_active Expired - Fee Related
- 2004-09-21 US US10/573,516 patent/US7750161B2/en not_active Expired - Fee Related
- 2004-09-21 KR KR1020067005848A patent/KR20070014108A/ko not_active Withdrawn
- 2004-09-21 RU RU2006113948/04A patent/RU2006113948A/ru unknown
- 2004-09-21 MX MXPA06003264A patent/MXPA06003264A/es unknown
- 2004-09-24 AR ARP040103475A patent/AR045949A1/es unknown
- 2004-09-24 TW TW093129149A patent/TW200526630A/zh unknown
2006
- 2006-03-22 IL IL174497A patent/IL174497A0/en unknown
- 2006-03-24 ZA ZA200602442A patent/ZA200602442B/en unknown
- 2006-03-27 NO NO20061395A patent/NO20061395L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
DE602004020486D1 (de)	2009-05-20
EP1670470A1 (de)	2006-06-21
CA2540196C (en)	2012-03-20
IL174497A0 (en)	2006-08-01
JP4851328B2 (ja)	2012-01-11
CA2540196A1 (en)	2005-04-07
TW200526630A (en)	2005-08-16
CN1856305B (zh)	2010-04-28
MXPA06003264A (es)	2006-06-08
ZA200602442B (en)	2007-09-26
WO2005030209A1 (en)	2005-04-07
RU2006113948A (ru)	2007-11-10
AU2004275488A1 (en)	2005-04-07
KR20070014108A (ko)	2007-01-31
JP2007506692A (ja)	2007-03-22
US7750161B2 (en)	2010-07-06
BRPI0414777A (pt)	2006-11-21
EP1670470B1 (de)	2009-04-08
AR045949A1 (es)	2005-11-16
US20070043081A1 (en)	2007-02-22
ATE427748T1 (de)	2009-04-15
CN1856305A (zh)	2006-11-01
WO2005030209A8 (en)	2006-05-11

Legal Events

Date	Code	Title	Description
2007-08-20	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
NO20050932L (no)	2005-04-15	1-pyridin-4-yl-ureaderivater
NO20050290L (no)	2005-01-19	Nye tetrahydropyridin-derivater som renin-inhibitorer
NO20061395L (no)	2006-06-22	Nye pyridinderivater
NO20042844L (no)	2004-08-23	4-(piperidyl- og pyrrolidyl-alkyl-ureido)-kinoliner som uprotensin II reseptor-antagonister
NO20051102L (no)	2005-05-04	Sulfonylamino-eddiksyre-derivater
NO20032905D0 (no)	2003-06-24	Nye benzodiazepiner og beslektede heterocykliske derivater som er anvendelige som orexinreseptorantagonister
NO20070224L (no)	2007-04-02	2-karbamid-4-fenyltiazolderivater, fremstilling og terapeutisk anvendelse derav
NO20066055L (no)	2007-01-24	Pyridinderivater
NO20074258L (no)	2007-11-27	Pyridin-2-karboksamidderivater som MGLUR5 antagonister
NO20060001L (no)	2006-03-02	Nye P2X7-reseptorantagonister og deres anvendelse
ECSP045378A (es)	2004-11-26	Derivados novedosos de diazabiciclononeno
NO20082269L (no)	2008-05-20	Nye piperaziner som antimalariamidler
NO20064584L (no)	2006-10-10	Tetrahydropyridoindolderivater
NO20056192L (no)	2005-12-27	Kapaseinhibitorer og anvendelse derav
NO20076682L (no)	2008-03-05	Nye pyridinanaloger
DE602004011204D1 (de)	2008-02-21	Quinoxalin-3-on-verdindungen als orexin-rezeptor antagonisten.
NO20054974L (no)	2005-11-28	9-azabicyklo(3.3.1)non-6-en derivater med et heteroatom i 3-posisjonen som renin inhibitorer
NO20055623L (no)	2005-11-29	Azabicyklononenderivater
NO20055624L (no)	2005-11-29	Tropanderivater og deres anvendelse som Ace-inhibitorer
NO20060963L (no)	2006-02-27	Nikotinamidderivater anvendelige som PDE4-inhibitorer
DE60326263D1 (de)	2009-04-02	Pyrimidin-sulfonamide und ihre verwendung als endothelin-rezeptor-antagonisten
DK1307445T3 (da)	2006-04-10	Benzofuranderivater og deres anvendelse som antibakterielle midler
ATE462703T1 (de)	2010-04-15	Bicyclononen-derivate als renin-inhibitoren
NO20073046L (no)	2007-06-25	Utvalgte benzofuranderivater
TW200628468A (en)	2006-08-16	Bicyclononene derivatives