ATE431326T1 - Calcium-dicarboxylatether, verfahren zu deren herstellung - Google Patents

Calcium-dicarboxylatether, verfahren zu deren herstellung

Info

Publication number
ATE431326T1
ATE431326T1 AT01900037T AT01900037T ATE431326T1 AT E431326 T1 ATE431326 T1 AT E431326T1 AT 01900037 T AT01900037 T AT 01900037T AT 01900037 T AT01900037 T AT 01900037T AT E431326 T1 ATE431326 T1 AT E431326T1
Authority
AT
Austria
Prior art keywords
production
calcium dicarboxylate
dicarboxylate ether
ether
calcium
Prior art date
Application number
AT01900037T
Other languages
English (en)
Inventor
Howard ANDO
Donald BUTLER
Gary DOZEMAN
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Application granted granted Critical
Publication of ATE431326T1 publication Critical patent/ATE431326T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/125—Saturated compounds having only one carboxyl group and containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235—Saturated compounds containing more than one carboxyl group
    • C07C59/305—Saturated compounds containing more than one carboxyl group containing ether groups, groups, groups, or groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
AT01900037T 2000-01-25 2001-01-11 Calcium-dicarboxylatether, verfahren zu deren herstellung ATE431326T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17782300P 2000-01-25 2000-01-25
PCT/IB2001/000026 WO2001055078A1 (en) 2000-01-25 2001-01-11 Calcium dicarboxylate ethers, methods of making same, and treatment of vascular disease and diabetes therewith

Publications (1)

Publication Number Publication Date
ATE431326T1 true ATE431326T1 (de) 2009-05-15

Family

ID=22650106

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01900037T ATE431326T1 (de) 2000-01-25 2001-01-11 Calcium-dicarboxylatether, verfahren zu deren herstellung

Country Status (39)

Country Link
EP (1) EP1259474B1 (de)
JP (1) JP4750995B2 (de)
KR (1) KR20020073182A (de)
CN (1) CN1395555A (de)
AP (1) AP2002002587A0 (de)
AR (1) AR029436A1 (de)
AT (1) ATE431326T1 (de)
AU (1) AU2214001A (de)
BG (1) BG106851A (de)
BR (1) BR0107763A (de)
CA (1) CA2397960C (de)
CO (1) CO5261537A1 (de)
CZ (1) CZ20022474A3 (de)
DE (1) DE60138686D1 (de)
DK (1) DK1259474T3 (de)
DZ (1) DZ3239A1 (de)
EA (1) EA004862B1 (de)
EE (1) EE200200404A (de)
ES (1) ES2324281T3 (de)
GE (1) GEP20053428B (de)
GT (1) GT200100015A (de)
HN (1) HN2001000011A (de)
HU (1) HUP0204422A3 (de)
IL (1) IL150541A0 (de)
IS (1) IS6442A (de)
MA (1) MA26867A1 (de)
MX (1) MXPA02007223A (de)
NO (1) NO20023526L (de)
NZ (1) NZ519550A (de)
OA (1) OA12166A (de)
PA (1) PA8510601A1 (de)
PE (1) PE20011064A1 (de)
PL (1) PL357076A1 (de)
SK (1) SK10622002A3 (de)
SV (1) SV2002000290A (de)
TN (1) TNSN01013A1 (de)
UY (1) UY26550A1 (de)
WO (1) WO2001055078A1 (de)
ZA (1) ZA200205880B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1045691T1 (en) * 1997-12-12 2005-04-30 Warner-Lambert Company Llc Statin-carboxyalkylether combinations
EP1539127A1 (de) * 2002-08-22 2005-06-15 Warner-Lambert Company Llc Verfahren zur behandlung von osteoarthritis
CA2605331A1 (en) * 2005-04-19 2006-11-02 Eisai R & D Management Co., Ltd. Calcium bis[(2s)-3-[3-[(2s)-3-(4-chloro-2-cyanophenoxy)-2- fluoropropoxy]phenyl]-2-isopropoxypropionate] and intermediate thereof
US7816405B2 (en) 2005-04-19 2010-10-19 Eisai R&D Management Co., Ltd. Calcium bis [(2S)-3-[3-[(2S)-3-(4-chloro-2-cyanophenoxy)-2-fluoropropoxy]phenyl ]-2-isopropoxypropionate] and intermediate thereof
WO2016077832A2 (en) * 2014-11-14 2016-05-19 Gemphire Therapeutics Inc. PROCESSES AND INTERMEDIATES FOR PREPARING α,ω-DICARBOXYLIC ACID-TERMINATED DIALKANE ETHERS
CA3059073A1 (en) * 2017-04-18 2018-10-25 Gemphire Therapeutics Inc. Gemcabene, pharmaceutically acceptable salts thereof, compositions thereof and methods of use therefor
JP2022505033A (ja) * 2018-10-18 2022-01-14 ジェムフィアー セラピューティクス インコーポレイテッド ゲムカベン、薬学的に許容されるその塩、その組成物、およびその使用方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5648387A (en) 1995-03-24 1997-07-15 Warner-Lambert Company Carboxyalkylethers, formulations, and treatment of vascular diseases
NZ503982A (en) 1997-12-12 2002-03-28 Warner Lambert Co Statin-carboxyalkylether combinations useful for treating vascular disorders and diabetes mellitus

Also Published As

Publication number Publication date
SV2002000290A (es) 2002-07-16
PA8510601A1 (es) 2002-08-26
DE60138686D1 (de) 2009-06-25
DZ3239A1 (fr) 2001-08-02
EA004862B1 (ru) 2004-08-26
DK1259474T3 (da) 2009-07-20
TNSN01013A1 (fr) 2005-11-10
IL150541A0 (en) 2003-02-12
EP1259474A1 (de) 2002-11-27
CA2397960C (en) 2008-09-09
HUP0204422A3 (en) 2003-08-28
CN1395555A (zh) 2003-02-05
EP1259474B1 (de) 2009-05-13
NO20023526L (no) 2002-08-27
BG106851A (en) 2003-01-31
AU2214001A (en) 2001-08-07
GEP20053428B (en) 2005-01-25
MA26867A1 (fr) 2004-12-20
SK10622002A3 (sk) 2003-07-01
KR20020073182A (ko) 2002-09-19
NO20023526D0 (no) 2002-07-24
CO5261537A1 (es) 2003-03-31
MXPA02007223A (es) 2002-11-29
JP4750995B2 (ja) 2011-08-17
ZA200205880B (en) 2003-07-23
BR0107763A (pt) 2002-11-12
CZ20022474A3 (cs) 2003-06-18
ES2324281T3 (es) 2009-08-04
IS6442A (is) 2002-06-25
JP2003520835A (ja) 2003-07-08
EE200200404A (et) 2003-10-15
AP2002002587A0 (en) 2002-09-30
HN2001000011A (es) 2001-06-13
HUP0204422A2 (en) 2003-05-28
EA200200641A1 (ru) 2002-12-26
AR029436A1 (es) 2003-06-25
UY26550A1 (es) 2001-08-27
NZ519550A (en) 2003-11-28
PE20011064A1 (es) 2001-10-22
GT200100015A (es) 2001-10-19
WO2001055078A1 (en) 2001-08-02
CA2397960A1 (en) 2001-08-02
OA12166A (en) 2003-11-07
PL357076A1 (en) 2004-07-12

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Legal Events

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