MA26867A1 - Ether-dicarboxylates de calcium, procedes pour leur preparation et traitement de maladies vasculaires et du diabete avec ces composés - Google Patents
Ether-dicarboxylates de calcium, procedes pour leur preparation et traitement de maladies vasculaires et du diabete avec ces composésInfo
- Publication number
- MA26867A1 MA26867A1 MA26735A MA26735A MA26867A1 MA 26867 A1 MA26867 A1 MA 26867A1 MA 26735 A MA26735 A MA 26735A MA 26735 A MA26735 A MA 26735A MA 26867 A1 MA26867 A1 MA 26867A1
- Authority
- MA
- Morocco
- Prior art keywords
- treatment
- dicarboxylates
- diabetes
- preparation
- vascular diseases
- Prior art date
Links
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 title abstract 2
- 229910052791 calcium Inorganic materials 0.000 title abstract 2
- 239000011575 calcium Substances 0.000 title abstract 2
- 206010012601 diabetes mellitus Diseases 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 208000019553 vascular disease Diseases 0.000 title abstract 2
- SDMBRCRVFFHJKR-UHFFFAOYSA-N 6-(5-carboxy-5-methylhexoxy)-2,2-dimethylhexanoic acid Chemical compound OC(=O)C(C)(C)CCCCOCCCCC(C)(C)C(O)=O SDMBRCRVFFHJKR-UHFFFAOYSA-N 0.000 abstract 1
- 208000032928 Dyslipidaemia Diseases 0.000 abstract 1
- 208000017170 Lipid metabolism disease Diseases 0.000 abstract 1
- 150000001298 alcohols Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/125—Saturated compounds having only one carboxyl group and containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/235—Saturated compounds containing more than one carboxyl group
- C07C59/305—Saturated compounds containing more than one carboxyl group containing ether groups, groups, groups, or groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
DEPOSANT Société dite: WARNER-LAMBERTCOMPANY REVENDICATION DE PRIORITES US 25 Janvier 2000 60/177,823 "Ether-dicarboxylates de calcium, procédés pour leur préparation et traitement de maladies vasculaires et du diabète avec ces composés" Les produits de solvatation avec des alcools et l'eau du sel monocalcique d'acide 6-(5-carboxy-5-méthyi-hexyloxy)-2,2-diméthyl-hexanoïque sont cristallins et répondent à la formule (I), dans laquelle R1 représente H ou un groupe alkyle inférieur, et x est un nombre de 0 à 10, et sont utiles pour le traitement de la dyslipidémie.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17782300P | 2000-01-25 | 2000-01-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA26867A1 true MA26867A1 (fr) | 2004-12-20 |
Family
ID=22650106
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA26735A MA26867A1 (fr) | 2000-01-25 | 2002-07-22 | Ether-dicarboxylates de calcium, procedes pour leur preparation et traitement de maladies vasculaires et du diabete avec ces composés |
Country Status (39)
| Country | Link |
|---|---|
| EP (1) | EP1259474B1 (fr) |
| JP (1) | JP4750995B2 (fr) |
| KR (1) | KR20020073182A (fr) |
| CN (1) | CN1395555A (fr) |
| AP (1) | AP2002002587A0 (fr) |
| AR (1) | AR029436A1 (fr) |
| AT (1) | ATE431326T1 (fr) |
| AU (1) | AU2214001A (fr) |
| BG (1) | BG106851A (fr) |
| BR (1) | BR0107763A (fr) |
| CA (1) | CA2397960C (fr) |
| CO (1) | CO5261537A1 (fr) |
| CZ (1) | CZ20022474A3 (fr) |
| DE (1) | DE60138686D1 (fr) |
| DK (1) | DK1259474T3 (fr) |
| DZ (1) | DZ3239A1 (fr) |
| EA (1) | EA004862B1 (fr) |
| EE (1) | EE200200404A (fr) |
| ES (1) | ES2324281T3 (fr) |
| GE (1) | GEP20053428B (fr) |
| GT (1) | GT200100015A (fr) |
| HN (1) | HN2001000011A (fr) |
| HU (1) | HUP0204422A3 (fr) |
| IL (1) | IL150541A0 (fr) |
| IS (1) | IS6442A (fr) |
| MA (1) | MA26867A1 (fr) |
| MX (1) | MXPA02007223A (fr) |
| NO (1) | NO20023526L (fr) |
| NZ (1) | NZ519550A (fr) |
| OA (1) | OA12166A (fr) |
| PA (1) | PA8510601A1 (fr) |
| PE (1) | PE20011064A1 (fr) |
| PL (1) | PL357076A1 (fr) |
| SK (1) | SK10622002A3 (fr) |
| SV (1) | SV2002000290A (fr) |
| TN (1) | TNSN01013A1 (fr) |
| UY (1) | UY26550A1 (fr) |
| WO (1) | WO2001055078A1 (fr) |
| ZA (1) | ZA200205880B (fr) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1481962A1 (fr) * | 1997-12-12 | 2004-12-01 | Warner-Lambert Company LLC | Nouveau carboxyéthylether reduisant la cholesterolémie |
| AU2003255937A1 (en) * | 2002-08-22 | 2004-03-11 | Warner-Lambert Company Llc | Method of treating osteoarthritis |
| US7816405B2 (en) | 2005-04-19 | 2010-10-19 | Eisai R&D Management Co., Ltd. | Calcium bis [(2S)-3-[3-[(2S)-3-(4-chloro-2-cyanophenoxy)-2-fluoropropoxy]phenyl ]-2-isopropoxypropionate] and intermediate thereof |
| JPWO2006115130A1 (ja) * | 2005-04-19 | 2008-12-18 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ビス［（２ｓ）−３−［３−［（２ｓ）−３−（４−クロロ−２−シアノフェノキシ）−２−フルオロプロポキシ］フェニル］−２−イソプロポキシプロピオン酸］カルシウム及びその中間体 |
| SG10201912713YA (en) * | 2014-11-14 | 2020-02-27 | Gemphire Therapeutics Inc | PROCESSES AND INTERMEDIATES FOR PREPARING α,ω-DICARBOXYLIC ACID-TERMINATED DIALKANE ETHERS |
| CA3059073A1 (fr) | 2017-04-18 | 2018-10-25 | Gemphire Therapeutics Inc. | Gemcabene, sels pharmaceutiquement acceptables de celui-ci, compositions de celui-ci et procedes d'utilisation de celui-ci |
| WO2020081837A1 (fr) * | 2018-10-18 | 2020-04-23 | Gemphire Therapeutics Inc. | Gemcabène, sels pharmaceutiquement acceptables de celui-ci, compositions correspondantes et procédés d'utilisation associés |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5648387A (en) | 1995-03-24 | 1997-07-15 | Warner-Lambert Company | Carboxyalkylethers, formulations, and treatment of vascular diseases |
| NZ503982A (en) | 1997-12-12 | 2002-03-28 | Warner Lambert Co | Statin-carboxyalkylether combinations useful for treating vascular disorders and diabetes mellitus |
-
2001
- 2001-01-11 EP EP01900037A patent/EP1259474B1/fr not_active Expired - Lifetime
- 2001-01-11 CN CN01804045A patent/CN1395555A/zh active Pending
- 2001-01-11 IL IL15054101A patent/IL150541A0/xx unknown
- 2001-01-11 DZ DZ013239A patent/DZ3239A1/fr active
- 2001-01-11 DE DE60138686T patent/DE60138686D1/de not_active Expired - Lifetime
- 2001-01-11 SK SK1062-2002A patent/SK10622002A3/sk not_active Application Discontinuation
- 2001-01-11 NZ NZ519550A patent/NZ519550A/en unknown
- 2001-01-11 AU AU22140/01A patent/AU2214001A/en not_active Abandoned
- 2001-01-11 EA EA200200641A patent/EA004862B1/ru not_active IP Right Cessation
- 2001-01-11 MX MXPA02007223A patent/MXPA02007223A/es active IP Right Grant
- 2001-01-11 DK DK01900037T patent/DK1259474T3/da active
- 2001-01-11 HU HU0204422A patent/HUP0204422A3/hu unknown
- 2001-01-11 CZ CZ20022474A patent/CZ20022474A3/cs unknown
- 2001-01-11 KR KR1020027009519A patent/KR20020073182A/ko not_active Ceased
- 2001-01-11 AP APAP/P/2002/002587A patent/AP2002002587A0/en unknown
- 2001-01-11 CA CA002397960A patent/CA2397960C/fr not_active Expired - Lifetime
- 2001-01-11 ES ES01900037T patent/ES2324281T3/es not_active Expired - Lifetime
- 2001-01-11 AT AT01900037T patent/ATE431326T1/de not_active IP Right Cessation
- 2001-01-11 JP JP2001555021A patent/JP4750995B2/ja not_active Expired - Fee Related
- 2001-01-11 GE GE4872A patent/GEP20053428B/en unknown
- 2001-01-11 BR BR0107763-5A patent/BR0107763A/pt not_active IP Right Cessation
- 2001-01-11 WO PCT/IB2001/000026 patent/WO2001055078A1/fr not_active Ceased
- 2001-01-11 OA OA1200200226A patent/OA12166A/en unknown
- 2001-01-11 EE EEP200200404A patent/EE200200404A/xx unknown
- 2001-01-11 PL PL01357076A patent/PL357076A1/xx not_active Application Discontinuation
- 2001-01-22 UY UY26550A patent/UY26550A1/es not_active Application Discontinuation
- 2001-01-22 SV SV2001000290A patent/SV2002000290A/es not_active Application Discontinuation
- 2001-01-23 PA PA20018510601A patent/PA8510601A1/es unknown
- 2001-01-23 GT GT200100015A patent/GT200100015A/es unknown
- 2001-01-23 AR ARP010100284A patent/AR029436A1/es unknown
- 2001-01-24 TN TNTNSN01013A patent/TNSN01013A1/fr unknown
- 2001-01-24 HN HN2001000011A patent/HN2001000011A/es unknown
- 2001-01-24 PE PE2001000076A patent/PE20011064A1/es not_active Application Discontinuation
- 2001-01-24 CO CO01005267A patent/CO5261537A1/es not_active Application Discontinuation
-
2002
- 2002-06-20 BG BG106851A patent/BG106851A/xx unknown
- 2002-06-25 IS IS6442A patent/IS6442A/is unknown
- 2002-07-22 MA MA26735A patent/MA26867A1/fr unknown
- 2002-07-23 ZA ZA200205880A patent/ZA200205880B/xx unknown
- 2002-07-24 NO NO20023526A patent/NO20023526L/no not_active Application Discontinuation
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