ATE431365T1 - Verfahren zur aufreinigung des alpha-1-proteinase-inhibitors (a1pi) - Google Patents
Verfahren zur aufreinigung des alpha-1-proteinase-inhibitors (a1pi)Info
- Publication number
- ATE431365T1 ATE431365T1 AT06776720T AT06776720T ATE431365T1 AT E431365 T1 ATE431365 T1 AT E431365T1 AT 06776720 T AT06776720 T AT 06776720T AT 06776720 T AT06776720 T AT 06776720T AT E431365 T1 ATE431365 T1 AT E431365T1
- Authority
- AT
- Austria
- Prior art keywords
- a1pi
- alpha
- proteinase inhibitor
- purifying
- purification
- Prior art date
Links
- 102000015395 alpha 1-Antitrypsin Human genes 0.000 title abstract 7
- 108010050122 alpha 1-Antitrypsin Proteins 0.000 title abstract 7
- 238000000034 method Methods 0.000 title abstract 3
- 238000000746 purification Methods 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 238000010257 thawing Methods 0.000 abstract 1
- 238000005406 washing Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
- C07K14/8121—Serpins
- C07K14/8125—Alpha-1-antitrypsin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/202,349 US7807435B2 (en) | 2005-08-11 | 2005-08-11 | Method for the purification of alpha-1 proteinase inhibitor (a1PI) |
| PCT/EP2006/007899 WO2007017277A1 (en) | 2005-08-11 | 2006-08-09 | METHOD FOR THE PURIFICATION OF ALPHA-1 PROTEINASE INHIBITOR (a1PI) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE431365T1 true ATE431365T1 (de) | 2009-05-15 |
Family
ID=37401472
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06776720T ATE431365T1 (de) | 2005-08-11 | 2006-08-09 | Verfahren zur aufreinigung des alpha-1-proteinase-inhibitors (a1pi) |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7807435B2 (de) |
| EP (1) | EP1913024B1 (de) |
| JP (2) | JP5091862B2 (de) |
| AT (1) | ATE431365T1 (de) |
| AU (1) | AU2006278143B2 (de) |
| CA (1) | CA2614838A1 (de) |
| DE (1) | DE602006006840D1 (de) |
| ES (1) | ES2325819T3 (de) |
| WO (1) | WO2007017277A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8772462B2 (en) | 2010-05-26 | 2014-07-08 | Baxter International Inc. | Removal of serine proteases by treatment with finely divided silicon dioxide |
| AU2010202125B1 (en) | 2010-05-26 | 2010-09-02 | Takeda Pharmaceutical Company Limited | A method to produce an immunoglobulin preparation with improved yield |
| TWI629283B (zh) | 2012-02-23 | 2018-07-11 | 巴克斯歐塔公司 | 來自血漿中的免疫球蛋白之ｉ-ｉｖ-１部分沉澱 |
| US9353165B2 (en) * | 2012-07-25 | 2016-05-31 | Grifols, S.A. | Purification of cell culture derived alpha1 protease inhibitor |
| WO2016161418A1 (en) * | 2015-04-02 | 2016-10-06 | Kieu Hoang | A method of manufacturing an afod intra venous injection from fraction iv |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4629567A (en) * | 1986-03-07 | 1986-12-16 | Smithkline-Rit | Alpha-1-antiprotease purification |
| US6284874B1 (en) | 1994-06-17 | 2001-09-04 | Alpha Therapeutic Corporation | Process for separating α1-proteinase inhibitor from cohn fraction IV1 and IV4 paste |
| US5610285A (en) * | 1994-08-24 | 1997-03-11 | Bayer Corporation | Purification of α-1 proteinase inhibitor using novel chromatographic separation conditions |
| DE19531637A1 (de) * | 1995-08-28 | 1997-03-06 | Immuno Ag | Pharmazeutische Zusammensetzung zur Behandlung von Blutgerinnungsstörugnen, Verfahren zur Herstellung derselben und deren Verwendung |
| US5616693A (en) | 1996-07-01 | 1997-04-01 | Alpha Therapeutic Corporation | Process for seperating alpha-1-proteinase inhibitor from COHN IV1 +1V4 paste |
| US6093804A (en) * | 1998-09-24 | 2000-07-25 | American National Red Cross | Method for purification of alpha-1 proteinase inhibitor |
-
2005
- 2005-08-11 US US11/202,349 patent/US7807435B2/en not_active Expired - Lifetime
-
2006
- 2006-08-09 JP JP2008525482A patent/JP5091862B2/ja active Active
- 2006-08-09 AT AT06776720T patent/ATE431365T1/de active
- 2006-08-09 EP EP06776720A patent/EP1913024B1/de active Active
- 2006-08-09 AU AU2006278143A patent/AU2006278143B2/en active Active
- 2006-08-09 CA CA002614838A patent/CA2614838A1/en not_active Abandoned
- 2006-08-09 WO PCT/EP2006/007899 patent/WO2007017277A1/en not_active Ceased
- 2006-08-09 ES ES06776720T patent/ES2325819T3/es active Active
- 2006-08-09 DE DE602006006840T patent/DE602006006840D1/de active Active
-
2012
- 2012-03-19 JP JP2012062481A patent/JP2012140452A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2006278143A1 (en) | 2007-02-15 |
| DE602006006840D1 (de) | 2009-06-25 |
| WO2007017277A1 (en) | 2007-02-15 |
| US7807435B2 (en) | 2010-10-05 |
| CA2614838A1 (en) | 2007-02-15 |
| HK1119185A1 (en) | 2009-02-27 |
| ES2325819T3 (es) | 2009-09-18 |
| US20070037270A1 (en) | 2007-02-15 |
| EP1913024B1 (de) | 2009-05-13 |
| AU2006278143B2 (en) | 2011-12-22 |
| JP2012140452A (ja) | 2012-07-26 |
| JP5091862B2 (ja) | 2012-12-05 |
| JP2009504594A (ja) | 2009-02-05 |
| EP1913024A1 (de) | 2008-04-23 |
| WO2007017277A8 (en) | 2007-04-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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