ATE432071T1 - Fettsäureanaloge zur behandlung von entzündungs- und autoimmunerkrankungen - Google Patents
Fettsäureanaloge zur behandlung von entzündungs- und autoimmunerkrankungenInfo
- Publication number
- ATE432071T1 ATE432071T1 AT01998347T AT01998347T ATE432071T1 AT E432071 T1 ATE432071 T1 AT E432071T1 AT 01998347 T AT01998347 T AT 01998347T AT 01998347 T AT01998347 T AT 01998347T AT E432071 T1 ATE432071 T1 AT E432071T1
- Authority
- AT
- Austria
- Prior art keywords
- fatty acid
- acid analogues
- inflammatory
- treatment
- autoimmune diseases
- Prior art date
Links
- 235000014113 dietary fatty acids Nutrition 0.000 title abstract 2
- 229930195729 fatty acid Natural products 0.000 title abstract 2
- 239000000194 fatty acid Substances 0.000 title abstract 2
- 150000004665 fatty acids Chemical class 0.000 title abstract 2
- 208000027866 inflammatory disease Diseases 0.000 title abstract 2
- 208000023275 Autoimmune disease Diseases 0.000 title 1
- 230000002757 inflammatory effect Effects 0.000 title 1
- IPBCWPPBAWQYOO-UHFFFAOYSA-N 2-(tetradecylthio)acetic acid Chemical compound CCCCCCCCCCCCCCSCC(O)=O IPBCWPPBAWQYOO-UHFFFAOYSA-N 0.000 abstract 1
- LUQGQZIVDLUXLE-UHFFFAOYSA-N CCCCCCCCCCCCCCCC(O)=[Se] Chemical compound CCCCCCCCCCCCCCCC(O)=[Se] LUQGQZIVDLUXLE-UHFFFAOYSA-N 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 201000009594 Systemic Scleroderma Diseases 0.000 abstract 1
- 208000004732 Systemic Vasculitis Diseases 0.000 abstract 1
- 206010042953 Systemic sclerosis Diseases 0.000 abstract 1
- 206010047115 Vasculitis Diseases 0.000 abstract 1
- 201000001981 dermatomyositis Diseases 0.000 abstract 1
- 208000005987 polymyositis Diseases 0.000 abstract 1
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 201000000596 systemic lupus erythematosus Diseases 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Communicable Diseases (AREA)
- Endocrinology (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Pulmonology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Virology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO20006008A NO20006008L (no) | 2000-11-28 | 2000-11-28 | Fettsyreanaloger for behandling av inflammatoriske og autoimmune sykdommer |
| PCT/NO2001/000470 WO2002043728A1 (en) | 2000-11-28 | 2001-11-27 | Fatty acid analogues for the treatment of inflammatory and autoimmune disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE432071T1 true ATE432071T1 (de) | 2009-06-15 |
Family
ID=19911849
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01998347T ATE432071T1 (de) | 2000-11-28 | 2001-11-27 | Fettsäureanaloge zur behandlung von entzündungs- und autoimmunerkrankungen |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US8088825B2 (de) |
| EP (1) | EP1351672B1 (de) |
| JP (1) | JP4368579B2 (de) |
| KR (1) | KR100905335B1 (de) |
| CN (1) | CN1296039C (de) |
| AT (1) | ATE432071T1 (de) |
| AU (2) | AU2316202A (de) |
| BR (1) | BR0115527A (de) |
| CA (1) | CA2457925C (de) |
| DE (1) | DE60138834D1 (de) |
| ES (1) | ES2326159T3 (de) |
| MX (1) | MXPA03004427A (de) |
| NO (1) | NO20006008L (de) |
| NZ (1) | NZ525889A (de) |
| RU (1) | RU2259823C2 (de) |
| WO (1) | WO2002043728A1 (de) |
| ZA (1) | ZA200303668B (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO328803B1 (no) | 2000-03-03 | 2010-05-18 | Thia Medica | Nye fettsyreanaloger |
| AU2003278602C1 (en) | 2002-06-20 | 2010-08-12 | Pronova Biopharma Norge As | Sulfur-containing phospholipid derivatives |
| JP2007522118A (ja) * | 2004-01-30 | 2007-08-09 | ペプリン バイオリピッズ ピーティーワイ エルティーディー | 治療用分子および担体分子 |
| JP2008506773A (ja) * | 2004-07-19 | 2008-03-06 | ティア メディカ アクスイェ セルスカプ | タンパク質材料と非酸化性脂肪酸体を含む組成物 |
| WO2009006668A1 (en) * | 2007-02-05 | 2009-01-15 | Children, Youth And Women's Health Service | Modulators of antigen-dependent t cell proliferation |
| DE102011050519A1 (de) * | 2011-05-20 | 2012-11-22 | Universität Rostock | Alkylschwefelalkansäurederivate und ihre pharmazeutisch verträglichen Salze zur Behandlung chronisch entzündlicher Erkrankungen |
| WO2014140934A2 (en) | 2013-03-11 | 2014-09-18 | Life Science Nutrition As | Natural lipids containing non-oxidizable fatty acids |
| AU2014228387B2 (en) | 2013-03-11 | 2016-09-01 | Sciadonics, Inc. | Lipid compositions containing bioactive fatty acids |
| AU2018354090B2 (en) | 2017-10-23 | 2024-10-24 | Epitracker, Inc. | Fatty acid analogs and their use in the treatment of conditions related to metabolic syndrome |
| EP3796976A4 (de) | 2018-05-23 | 2022-03-30 | Epitracker, Inc. | Zusammensetzungen und verfahren zur diagnose und behandlung von alterungs- und langlebigen bedingungen |
| EP3908374A4 (de) | 2019-01-09 | 2022-12-28 | Epitracker, Inc. | Zusammensetzungen und verfahren zur diagnose und behandlung von neurodegenerativen erkrankungen |
| JP7404382B2 (ja) | 2019-03-04 | 2023-12-25 | エピトラッカー インコーポレイテッド | 脂肪酸アナログ、ならびに認知機能障害、行動症状および慢性疼痛の処置におけるそれらの使用 |
| JP2024539823A (ja) | 2021-11-03 | 2024-10-31 | エピトラッカー インコーポレイテッド | 老化の質および寿命に関係する状態の治療のためのペンタデカノイルカルニチン |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS56164120A (en) * | 1980-05-22 | 1981-12-17 | Chisso Corp | Antitumor agent |
| FR2631339B1 (fr) * | 1988-05-10 | 1990-11-16 | Cird | Nouveaux eicosanoides sulfures et leur application en pharmacie et en cosmetique |
| DE4120917A1 (de) * | 1991-06-25 | 1993-01-07 | Basf Ag | Ester von fettsaeuren mit aminoalkoholen zur verwendung bei der bekaempfung von krankheiten |
| US5807884A (en) * | 1992-10-30 | 1998-09-15 | Emory University | Treatment for atherosclerosis and other cardiovascular and inflammatory diseases |
| US5618955A (en) * | 1992-11-30 | 1997-04-08 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Fatty acid derivatives and pharmaceutical compositions containing same |
| IL103932A (en) * | 1992-11-30 | 1997-02-18 | Yissum Res & Dev | Fatty acid and pharmaceutical compositions containing them |
| CN1088058C (zh) * | 1994-10-13 | 2002-07-24 | 肽技术有限公司 | 经修饰的多不饱和脂肪酸 |
| NO952796D0 (no) * | 1995-07-14 | 1995-07-14 | Rolf Berge | Fettsyre analoger med ikkeoksyderbart B-sete, fremstilling og anvendelse i krapeutiske preparater |
| RU2089179C1 (ru) * | 1995-12-14 | 1997-09-10 | Закрытое акционерное общество "ВАМ" | Стимулятор эндогенной продукции цитокинов и гепопоэтических факторов и способ его использования |
| US6262119B1 (en) * | 1996-04-12 | 2001-07-17 | Peptide Technology Limited | Methods of treating immunopathologies using polyunsaturated fatty acids |
| IL121165A0 (en) * | 1997-06-26 | 1997-11-20 | Yissum Res Dev Co | Pharmaceutical compositions containing carboxylic acids and derivatives thereof |
| WO1999058120A1 (en) * | 1998-05-08 | 1999-11-18 | Rolf Berge | USE OF NON-β-OXIDIZABLE FATTY ACID ANALOGUES FOR TREATMENT OF SYNDROME-X CONDITIONS |
| AUPQ291499A0 (en) * | 1999-09-17 | 1999-10-07 | Women's And Children's Hospital Adelaide | Novel nitro and sulphur containing compounds |
-
2000
- 2000-11-28 NO NO20006008A patent/NO20006008L/no not_active Application Discontinuation
-
2001
- 2001-11-27 BR BR0115527-0A patent/BR0115527A/pt not_active IP Right Cessation
- 2001-11-27 CN CNB018196969A patent/CN1296039C/zh not_active Expired - Fee Related
- 2001-11-27 AT AT01998347T patent/ATE432071T1/de not_active IP Right Cessation
- 2001-11-27 KR KR1020037007097A patent/KR100905335B1/ko not_active Expired - Fee Related
- 2001-11-27 CA CA2457925A patent/CA2457925C/en not_active Expired - Fee Related
- 2001-11-27 MX MXPA03004427A patent/MXPA03004427A/es active IP Right Grant
- 2001-11-27 WO PCT/NO2001/000470 patent/WO2002043728A1/en not_active Ceased
- 2001-11-27 AU AU2316202A patent/AU2316202A/xx active Pending
- 2001-11-27 EP EP01998347A patent/EP1351672B1/de not_active Expired - Lifetime
- 2001-11-27 AU AU2002223162A patent/AU2002223162B2/en not_active Ceased
- 2001-11-27 US US10/416,378 patent/US8088825B2/en not_active Expired - Fee Related
- 2001-11-27 DE DE60138834T patent/DE60138834D1/de not_active Expired - Lifetime
- 2001-11-27 ES ES01998347T patent/ES2326159T3/es not_active Expired - Lifetime
- 2001-11-27 RU RU2003115423/15A patent/RU2259823C2/ru not_active IP Right Cessation
- 2001-11-27 JP JP2002545699A patent/JP4368579B2/ja not_active Expired - Fee Related
- 2001-11-27 NZ NZ525889A patent/NZ525889A/en unknown
-
2003
- 2003-05-13 ZA ZA200303668A patent/ZA200303668B/en unknown
-
2011
- 2011-12-29 US US13/340,157 patent/US20120101161A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2457925A1 (en) | 2002-06-06 |
| KR100905335B1 (ko) | 2009-07-01 |
| ES2326159T3 (es) | 2009-10-02 |
| JP4368579B2 (ja) | 2009-11-18 |
| DE60138834D1 (de) | 2009-07-09 |
| AU2002223162B2 (en) | 2006-11-30 |
| JP2004514693A (ja) | 2004-05-20 |
| CA2457925C (en) | 2013-03-26 |
| NO20006008D0 (no) | 2000-11-28 |
| NO20006008L (no) | 2002-05-29 |
| US8088825B2 (en) | 2012-01-03 |
| CN1633284A (zh) | 2005-06-29 |
| EP1351672A1 (de) | 2003-10-15 |
| CN1296039C (zh) | 2007-01-24 |
| KR20030055322A (ko) | 2003-07-02 |
| NZ525889A (en) | 2004-10-29 |
| ZA200303668B (en) | 2004-01-30 |
| RU2259823C2 (ru) | 2005-09-10 |
| MXPA03004427A (es) | 2004-05-04 |
| EP1351672B1 (de) | 2009-05-27 |
| WO2002043728A1 (en) | 2002-06-06 |
| BR0115527A (pt) | 2003-09-23 |
| AU2316202A (en) | 2002-06-11 |
| HK1073793A1 (en) | 2005-10-21 |
| US20050165103A1 (en) | 2005-07-28 |
| US20120101161A1 (en) | 2012-04-26 |
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