ATE432936T1 - Imidazotriazin verbindungen zur behandlung von krebserkrankungen - Google Patents

Imidazotriazin verbindungen zur behandlung von krebserkrankungen

Info

Publication number
ATE432936T1
ATE432936T1 AT04749497T AT04749497T ATE432936T1 AT E432936 T1 ATE432936 T1 AT E432936T1 AT 04749497 T AT04749497 T AT 04749497T AT 04749497 T AT04749497 T AT 04749497T AT E432936 T1 ATE432936 T1 AT E432936T1
Authority
AT
Austria
Prior art keywords
compounds used
treat cancer
cancer diseases
imidazotriazine compounds
imidazotriazine
Prior art date
Application number
AT04749497T
Other languages
English (en)
Inventor
Mui Cheung
Nigel Paul King
Kevin Wayne Kuntz
Robert Anthony Mook Jr
Mark Pobanz
James Michael Salovich
Brian John Wilson
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Application granted granted Critical
Publication of ATE432936T1 publication Critical patent/ATE432936T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT04749497T 2003-04-01 2004-03-29 Imidazotriazin verbindungen zur behandlung von krebserkrankungen ATE432936T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45929303P 2003-04-01 2003-04-01
PCT/US2004/009553 WO2004087652A2 (en) 2003-04-01 2004-03-29 Imidazotriazine compounds

Publications (1)

Publication Number Publication Date
ATE432936T1 true ATE432936T1 (de) 2009-06-15

Family

ID=33131876

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04749497T ATE432936T1 (de) 2003-04-01 2004-03-29 Imidazotriazin verbindungen zur behandlung von krebserkrankungen

Country Status (7)

Country Link
US (1) US7462614B2 (de)
EP (1) EP1608656B1 (de)
JP (1) JP2006522127A (de)
AT (1) ATE432936T1 (de)
DE (1) DE602004021363D1 (de)
ES (1) ES2326808T3 (de)
WO (1) WO2004087652A2 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006258842B2 (en) * 2005-06-13 2011-09-15 Merck Sharp & Dohme Limited Therapeutic agents
EP2474546A1 (de) * 2006-01-23 2012-07-11 Vertex Pharmaceuticals Inc. Thiophencarboxamide als Proteinkinaseinhibitoren
US7504513B2 (en) 2006-02-27 2009-03-17 Hoffman-La Roche Inc. Thiazolyl-benzimidazoles
WO2007120760A2 (en) 2006-04-13 2007-10-25 Vertex Pharmaceuticals Incorporated Thiophene-carboxamides useful as inhibitors of protein kinases
WO2007139816A2 (en) 2006-05-23 2007-12-06 Vertex Pharmaceuticals Incorporated Thiophene-carboxamides useful as inhibitors of protein kinases
WO2007139795A1 (en) 2006-05-23 2007-12-06 Vertex Pharmaceuticals Incorporated Thiophene-carboxamides useful as inhibitors of protein kinases
EP2100894A1 (de) 2008-03-12 2009-09-16 4Sc Ag Pyridopyrimidinone verwendbar als Plk1 (polo-like kinase) Hemmen
WO2010121675A2 (en) 2008-12-18 2010-10-28 F. Hoffmann-La Roche Ag Thiazolyl-benzimidazoles
CN102532159B (zh) * 2010-11-12 2015-02-11 姚雪彪 动点马达蛋白CENP-E小分子抑制剂Syntelin
CN102827022A (zh) * 2012-09-21 2012-12-19 西华大学 2-乙酰氧基-n-(4-甲氧基苯基)苯甲酰胺及其制备方法和用途
IL296025A (en) * 2020-03-02 2022-10-01 Sironax Ltd Proptosis inhibitors - diarylamine para-acetamides
JP7774579B2 (ja) 2020-05-20 2025-11-21 シロナックス リミテッド． ピペラジン複素環アミド尿素類を含む受容体共役タンパク質１阻害剤
GB202018412D0 (en) * 2020-11-23 2021-01-06 Exscientia Ltd Malt-1 modulators ii
WO2025024726A1 (en) * 2023-07-26 2025-01-30 Kinnate Biopharma Inc. Inhibitors of cyclin-dependent kinase

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE791025A (fr) * 1971-11-19 1973-05-07 Allen & Hanburys Ltd Composes heterocycliques
GB1457873A (en) * 1973-01-04 1976-12-08 Allen & Hanburys Ltd Imidazotriazines
DK109578A (da) * 1977-03-25 1978-09-26 Allen & Hanburys Ltd Fremgangsmaade til fremstilling af heterocycliske forbindelser
US4308384A (en) * 1978-09-18 1981-12-29 Glaxo Group Limited Production of triazinones
JPS59164553A (ja) * 1983-03-08 1984-09-17 Fuji Photo Film Co Ltd カラ−写真感光材料
US4838925A (en) * 1986-04-25 1989-06-13 E. I. Du Pont De Nemours And Company Heterocyclic acyl sulfonamides
CA2395558C (en) * 1997-11-12 2007-07-17 Bayer Aktiengesellschaft Intermediates for 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors
DE10011530A1 (de) 2000-03-13 2001-09-27 Robert Elez Hochwirksame Antisense-Oligodesoxynucleotide gegen Polio-like Kinasel
DE10230604A1 (de) * 2002-07-08 2004-01-29 Bayer Ag Heterocyclisch substituierte Imidazotriazine

Also Published As

Publication number Publication date
EP1608656B1 (de) 2009-06-03
US7462614B2 (en) 2008-12-09
DE602004021363D1 (de) 2009-07-16
JP2006522127A (ja) 2006-09-28
ES2326808T3 (es) 2009-10-20
EP1608656A2 (de) 2005-12-28
US20060217382A1 (en) 2006-09-28
WO2004087652A2 (en) 2004-10-14
WO2004087652A3 (en) 2005-02-10

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