ATE432945T1 - Die aktivität von ccrl2 modulierende mittel und verfahren zu deren anwendung - Google Patents
Die aktivität von ccrl2 modulierende mittel und verfahren zu deren anwendungInfo
- Publication number
- ATE432945T1 ATE432945T1 AT04801256T AT04801256T ATE432945T1 AT E432945 T1 ATE432945 T1 AT E432945T1 AT 04801256 T AT04801256 T AT 04801256T AT 04801256 T AT04801256 T AT 04801256T AT E432945 T1 ATE432945 T1 AT E432945T1
- Authority
- AT
- Austria
- Prior art keywords
- ccrl2
- polypeptide
- activity
- methods
- mip
- Prior art date
Links
- 102100025074 C-C chemokine receptor-like 2 Human genes 0.000 title abstract 5
- 101000934394 Homo sapiens C-C chemokine receptor-like 2 Proteins 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 3
- 230000000694 effects Effects 0.000 title abstract 2
- 108010082155 Chemokine CCL18 Proteins 0.000 abstract 4
- 229920001184 polypeptide Polymers 0.000 abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 4
- 102100023701 C-C motif chemokine 18 Human genes 0.000 abstract 2
- 230000003993 interaction Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/52—Assays involving cytokines
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/715—Assays involving receptors, cell surface antigens or cell surface determinants for cytokines; for lymphokines; for interferons
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Obesity (AREA)
- Pathology (AREA)
- Endocrinology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Physics & Mathematics (AREA)
- Rheumatology (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Dermatology (AREA)
- AIDS & HIV (AREA)
- Emergency Medicine (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0328275A GB0328275D0 (en) | 2003-12-05 | 2003-12-05 | Ligands |
| GB0403014A GB0403014D0 (en) | 2004-02-11 | 2004-02-11 | Ligands |
| GB0418568A GB0418568D0 (en) | 2004-08-19 | 2004-08-19 | Ligands |
| PCT/GB2004/005057 WO2005057220A2 (en) | 2003-12-05 | 2004-12-02 | Agents modulating the activity of ccrl2 and methods of using the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE432945T1 true ATE432945T1 (de) | 2009-06-15 |
Family
ID=34681898
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04801256T ATE432945T1 (de) | 2003-12-05 | 2004-12-02 | Die aktivität von ccrl2 modulierende mittel und verfahren zu deren anwendung |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7521194B2 (de) |
| EP (1) | EP1692171B1 (de) |
| JP (1) | JP4734256B2 (de) |
| AT (1) | ATE432945T1 (de) |
| DE (1) | DE602004021419D1 (de) |
| ES (1) | ES2327126T3 (de) |
| WO (1) | WO2005057220A2 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0513878D0 (en) * | 2005-07-06 | 2005-08-10 | Mars Inc | Cat allergen |
| WO2007055636A1 (en) * | 2005-11-08 | 2007-05-18 | Astrazeneca Ab | Single nucleotide polymorphisms in the ckrx gene associated with respiratory disease |
| WO2008028692A2 (en) * | 2006-09-06 | 2008-03-13 | Humanitas Mirasole S.P.A. | Method for screening drug candidates for inflammatory diseases mediated by lps-inducible cc chemokine receptor mechanism |
| WO2010019811A2 (en) * | 2008-08-15 | 2010-02-18 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for screening for modulators of ccrl2 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE262914T1 (de) | 1993-12-22 | 2004-04-15 | Human Genome Sciences Inc | Entzündungsproteine aus makrophagen mip-3, mip-4 und mip-1gamma |
| AU3134695A (en) | 1995-05-05 | 1996-11-21 | Human Genome Sciences, Inc. | Human chemokine beta-8, chemokine beta-1 and macrophage infl ammatory protein-4 |
| JP2000514295A (ja) | 1996-07-05 | 2000-10-31 | シェーリング コーポレイション | 哺乳動物のケモカイン試薬 |
| WO2001066598A2 (en) | 2000-03-03 | 2001-09-13 | Icos Corporation | Chemoattractant receptor characterization and cell selection materials and methods and chemokine receptor ccr11 materials and methods |
| WO2002022856A2 (en) | 2000-09-13 | 2002-03-21 | Schering Corporation | Uses of the mammalian ccl18 and related reagents |
| EP1352240A2 (de) | 2001-01-18 | 2003-10-15 | Rijksuniversiteit Groningen | Klonierung und expression eines neuen mcp-rezeptors in glialzellen |
| WO2004045525A2 (en) * | 2002-11-15 | 2004-06-03 | Morehouse School Of Medicine | Anti-chemokine and associated receptor antibodies and uses for inhibition of inflammation. |
| GB0306428D0 (en) | 2003-03-20 | 2003-04-23 | Oxagen Ltd | Receptor proteins |
-
2004
- 2004-12-02 JP JP2006542005A patent/JP4734256B2/ja not_active Expired - Fee Related
- 2004-12-02 ES ES04801256T patent/ES2327126T3/es not_active Expired - Lifetime
- 2004-12-02 US US10/579,386 patent/US7521194B2/en not_active Expired - Fee Related
- 2004-12-02 AT AT04801256T patent/ATE432945T1/de not_active IP Right Cessation
- 2004-12-02 EP EP04801256A patent/EP1692171B1/de not_active Expired - Lifetime
- 2004-12-02 WO PCT/GB2004/005057 patent/WO2005057220A2/en not_active Ceased
- 2004-12-02 DE DE602004021419T patent/DE602004021419D1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1692171A2 (de) | 2006-08-23 |
| WO2005057220A3 (en) | 2006-02-02 |
| JP4734256B2 (ja) | 2011-07-27 |
| US7521194B2 (en) | 2009-04-21 |
| ES2327126T3 (es) | 2009-10-26 |
| US20070036781A1 (en) | 2007-02-15 |
| DE602004021419D1 (de) | 2009-07-16 |
| WO2005057220A2 (en) | 2005-06-23 |
| JP2007520210A (ja) | 2007-07-26 |
| EP1692171B1 (de) | 2009-06-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |