ATE443775T1 - Hif-prolylhydroxylase-aktivitätstest - Google Patents
Hif-prolylhydroxylase-aktivitätstestInfo
- Publication number
- ATE443775T1 ATE443775T1 AT05755214T AT05755214T ATE443775T1 AT E443775 T1 ATE443775 T1 AT E443775T1 AT 05755214 T AT05755214 T AT 05755214T AT 05755214 T AT05755214 T AT 05755214T AT E443775 T1 ATE443775 T1 AT E443775T1
- Authority
- AT
- Austria
- Prior art keywords
- activity test
- prolyl hydroxylase
- hydroxylase activity
- hif prolyl
- methods
- Prior art date
Links
- 102000004079 Prolyl Hydroxylases Human genes 0.000 title 1
- 108010043005 Prolyl Hydroxylases Proteins 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/902—Oxidoreductases (1.)
- G01N2333/90245—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57532404P | 2004-05-28 | 2004-05-28 | |
| PCT/US2005/018577 WO2005118836A2 (en) | 2004-05-28 | 2005-05-26 | Hif prolyl hydroxylase activity assay |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE443775T1 true ATE443775T1 (de) | 2009-10-15 |
Family
ID=34979114
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05755214T ATE443775T1 (de) | 2004-05-28 | 2005-05-26 | Hif-prolylhydroxylase-aktivitätstest |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20080113383A1 (de) |
| EP (1) | EP1766047B1 (de) |
| JP (1) | JP2008500834A (de) |
| AT (1) | ATE443775T1 (de) |
| AU (1) | AU2005250412B2 (de) |
| CA (1) | CA2567619A1 (de) |
| DE (1) | DE602005016800D1 (de) |
| ES (1) | ES2332798T3 (de) |
| IL (1) | IL179441A (de) |
| NZ (1) | NZ551632A (de) |
| WO (1) | WO2005118836A2 (de) |
| ZA (1) | ZA200610164B (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2044028B1 (de) | 2006-01-27 | 2012-05-16 | Fibrogen, Inc. | Cyanoisochinoline zur stabilisierung des hypoxie-induzierten faktors (hif) |
| US7588924B2 (en) | 2006-03-07 | 2009-09-15 | Procter & Gamble Company | Crystal of hypoxia inducible factor 1 alpha prolyl hydroxylase |
| BRPI0710527B8 (pt) | 2006-04-04 | 2021-05-25 | Fibrogen Inc | compostos de pirrolo- e tiazolo-piridina e composição farmacêutica que os compreende |
| MX2009000286A (es) | 2006-06-26 | 2009-03-20 | Procter & Gamble | Inhibidores de prolil hidroxilasa y metodos de uso. |
| MY160066A (en) | 2009-11-06 | 2017-02-15 | Aerpio Therapeutics Inc | Methods for increasing the stabilization of hypoxia inducible factor-1 alpha |
| CN103608346B (zh) | 2011-02-02 | 2016-06-15 | 菲布罗根有限公司 | 作为缺氧诱导因子(hif)羟化酶抑制剂的萘啶衍生物 |
| GB201102659D0 (en) | 2011-02-15 | 2011-03-30 | Isis Innovation | Assay |
| NO2686520T3 (de) | 2011-06-06 | 2018-03-17 | ||
| MX2013014310A (es) | 2011-06-06 | 2014-01-23 | Akebia Therapeutics Inc | Compuestos y composiciones para estabilizar el factor-2 alfa inducible por hipoxia como un metodo para tratar el cancer. |
| GB201113101D0 (en) | 2011-07-28 | 2011-09-14 | Isis Innovation | Assay |
| NZ700760A (en) | 2012-03-09 | 2016-08-26 | Fibrogen Inc | 4 -hydroxy- isoquinoline compounds as hif hydroxylase inhibitors |
| JP6491093B2 (ja) | 2012-07-16 | 2019-03-27 | フィブロジェン インコーポレイテッド | プロリルヒドロキシラーゼ阻害剤の結晶形態 |
| KR102145272B1 (ko) | 2012-07-16 | 2020-08-18 | 피브로겐, 인크. | 이소퀴놀린 화합물의 제조 방법 |
| CN114404414A (zh) | 2013-06-13 | 2022-04-29 | 阿克比治疗有限公司 | 用于治疗贫血症的组合物和方法 |
| EP3247355A4 (de) | 2015-01-23 | 2018-06-13 | Akebia Therapeutics, Inc. | Feste formen von 2-(5-(3-fluorphenyl)-3-hydroxypicolinamido)essigsäure, zusammensetzungen und verwendungen davon |
| EA036920B1 (ru) | 2015-04-01 | 2021-01-15 | Экебиа Терапьютикс, Инк. | Композиции и способы для лечения анемии |
| TW202406895A (zh) | 2018-05-09 | 2024-02-16 | 美商阿克比治療有限公司 | 用於製備2-[[5-(3-氯苯基)-3-羥基吡啶-2-羰基]胺基]乙酸之方法 |
| CN114577945B (zh) * | 2022-03-10 | 2023-06-02 | 中国科学院兰州化学物理研究所 | 一种从中药提取物中筛选脯氨酰羟化酶2抑制剂的胶束电动色谱方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040146964A1 (en) * | 2001-03-21 | 2004-07-29 | Maxwell Patrick Henry | Assays, methods and means |
| CN102526044A (zh) * | 2001-12-06 | 2012-07-04 | 法布罗根股份有限公司 | 提高内源性红细胞生成素(epo)的方法 |
-
2005
- 2005-05-26 NZ NZ551632A patent/NZ551632A/en unknown
- 2005-05-26 US US11/597,261 patent/US20080113383A1/en not_active Abandoned
- 2005-05-26 CA CA002567619A patent/CA2567619A1/en not_active Abandoned
- 2005-05-26 ZA ZA200610164A patent/ZA200610164B/en unknown
- 2005-05-26 WO PCT/US2005/018577 patent/WO2005118836A2/en not_active Ceased
- 2005-05-26 JP JP2007515346A patent/JP2008500834A/ja not_active Ceased
- 2005-05-26 DE DE602005016800T patent/DE602005016800D1/de not_active Expired - Lifetime
- 2005-05-26 EP EP05755214A patent/EP1766047B1/de not_active Expired - Lifetime
- 2005-05-26 ES ES05755214T patent/ES2332798T3/es not_active Expired - Lifetime
- 2005-05-26 AU AU2005250412A patent/AU2005250412B2/en not_active Ceased
- 2005-05-26 AT AT05755214T patent/ATE443775T1/de not_active IP Right Cessation
-
2006
- 2006-11-21 IL IL179441A patent/IL179441A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005118836A2 (en) | 2005-12-15 |
| IL179441A (en) | 2010-12-30 |
| ZA200610164B (en) | 2008-02-27 |
| AU2005250412A1 (en) | 2005-12-15 |
| WO2005118836A3 (en) | 2006-04-06 |
| ES2332798T3 (es) | 2010-02-12 |
| AU2005250412B2 (en) | 2009-09-17 |
| CA2567619A1 (en) | 2005-12-15 |
| HK1102197A1 (en) | 2007-11-09 |
| EP1766047A2 (de) | 2007-03-28 |
| EP1766047B1 (de) | 2009-09-23 |
| US20080113383A1 (en) | 2008-05-15 |
| NZ551632A (en) | 2009-09-25 |
| DE602005016800D1 (de) | 2009-11-05 |
| IL179441A0 (en) | 2007-05-15 |
| JP2008500834A (ja) | 2008-01-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |