ATE437225T1 - Verfahren zur polynukleotidsynthese - Google Patents

Verfahren zur polynukleotidsynthese

Info

Publication number
ATE437225T1
ATE437225T1 AT01967728T AT01967728T ATE437225T1 AT E437225 T1 ATE437225 T1 AT E437225T1 AT 01967728 T AT01967728 T AT 01967728T AT 01967728 T AT01967728 T AT 01967728T AT E437225 T1 ATE437225 T1 AT E437225T1
Authority
AT
Austria
Prior art keywords
polynucleotide synthesis
loops
polynucleotides
isothermal
synthesis
Prior art date
Application number
AT01967728T
Other languages
English (en)
Inventor
Kentaro Nagamine
Original Assignee
Eiken Chemical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=18768163&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE437225(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Eiken Chemical filed Critical Eiken Chemical
Application granted granted Critical
Publication of ATE437225T1 publication Critical patent/ATE437225T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
AT01967728T 2000-09-19 2001-09-19 Verfahren zur polynukleotidsynthese ATE437225T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000283862 2000-09-19
PCT/JP2001/008142 WO2002024902A1 (en) 2000-09-19 2001-09-19 Method of synthesizing polynucleotide

Publications (1)

Publication Number Publication Date
ATE437225T1 true ATE437225T1 (de) 2009-08-15

Family

ID=18768163

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01967728T ATE437225T1 (de) 2000-09-19 2001-09-19 Verfahren zur polynukleotidsynthese

Country Status (9)

Country Link
US (3) US7374913B2 (de)
EP (2) EP2031058B1 (de)
JP (2) JP4918210B2 (de)
CN (1) CN1222614C (de)
AT (1) ATE437225T1 (de)
AU (1) AU2001288065A1 (de)
DE (1) DE60139331D1 (de)
ES (2) ES2327712T3 (de)
WO (1) WO2002024902A1 (de)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8445664B2 (en) * 1998-06-24 2013-05-21 Enzo Diagnostics, Inc. Kits for amplifying and detecting nucleic acid sequences
DE60139331D1 (de) * 2000-09-19 2009-09-03 Eiken Chemical Verfahren zur polynukleotidsynthese
CN100516211C (zh) 2002-02-20 2009-07-22 希森美康株式会社 用于持家基因mRNA检测的核酸扩增用引物和使用该引物的检查方法
US8076080B2 (en) 2002-05-21 2011-12-13 Sysmex Corporation Nucleic acid amplification primers for detecting cytokeratins and examination method with the use of the primers
AU2003280603A1 (en) 2002-10-29 2004-05-25 Kabushiki Kaisha Dnaform Method of amplifying nucleic acid
CN1813064B (zh) * 2003-06-27 2011-11-02 荣研化学株式会社 检测sars冠状病毒的方法
JP2005110587A (ja) * 2003-10-08 2005-04-28 Sapporo Breweries Ltd アリサイクロバチラス属菌検出用プライマー
JP3897805B2 (ja) * 2003-12-25 2007-03-28 独立行政法人理化学研究所 核酸の増幅法およびこれを利用した変異核酸の検出法
JP2008000002A (ja) * 2004-09-30 2008-01-10 Sysmex Corp リブロース２リン酸カルボキシラーゼスモールチェーン１Ａ（ＲＢＣＳ−１Ａ）遺伝子及び／又は該遺伝子のｍＲＮＡを検出するための核酸増幅用プライマ、及び内部標準として該遺伝子及び／又は該遺伝子のｍＲＮＡを用いた検査方法。
ES2382446T3 (es) 2004-11-01 2012-06-08 Eiken Kagaku Kabushiki Kaisha Método de detección del virus de la gripe aviar H5
JP2006254784A (ja) * 2005-03-17 2006-09-28 Institute Of Physical & Chemical Research プライマーダイマーからの非特異的増幅を減少させる方法
FR2885140B1 (fr) 2005-04-29 2010-12-31 Millipore Corp Procede de detection et de caracterisation de microorgarnismes sur une membrane.
US8956850B2 (en) * 2008-06-05 2015-02-17 Butamax Advanced Biofuels Llc Enhanced pyruvate to acetolactate conversion in yeast
WO2007069331A1 (ja) * 2005-12-16 2007-06-21 Eiken Kagaku Kabushiki Kaisha ヒト免疫不全ウイルス１型の検出方法
JP4580875B2 (ja) * 2006-01-20 2010-11-17 株式会社東芝 核酸検出法のためのプライマーの設計方法
JP4881623B2 (ja) 2006-01-27 2012-02-22 シスメックス株式会社 Ｃｅａ核酸増幅用プライマー、プライマーセット、及びがんの診断支援方法
EP2108048A1 (de) * 2007-01-17 2009-10-14 Meridian Bioscience, Inc. Stabile reagenzien und kits für loop-vermittelte isotherme verstärkung
CA2622649C (en) 2007-03-09 2018-04-24 Riken Nucleic acid amplification method using primer exhibiting exciton effect
JP4410268B2 (ja) 2007-03-28 2010-02-03 株式会社東芝 メチレンテトラヒドロ葉酸還元酵素（ｍｔｈｆｒ）の遺伝子型を検出するための核酸プライマーセット及び核酸プローブ
JP4410269B2 (ja) 2007-03-28 2010-02-03 株式会社東芝 Ｎ−アセチルトランスフェラーゼ２（ｎａｔ２）の遺伝子型を検出するための核酸プライマーセット、キット、及び該プライマーセットを用いた検出方法
JP4490988B2 (ja) 2007-04-26 2010-06-30 株式会社東芝 血清アミロイドａ１（ｓａａ１）の遺伝子型を検出するための核酸プライマーセット、キット、及び該プライマーセットを用いた検出方法
US20100221787A1 (en) 2007-10-25 2010-09-02 Riken Isothermal amplification method and dna polymerase used in the same
US20110053168A1 (en) * 2008-03-28 2011-03-03 Sysmex Corporation REAGENT COMPRISING PRIMER FOR DETECTION OF mRNA FOR CYTOKERATIN-7
CN102105584B (zh) 2008-05-28 2014-05-14 花王株式会社 耐热菌类的检测方法
EP2325309B1 (de) 2008-05-29 2014-10-22 Kao Corporation Verfahren zum nachweis von paecilomyces variotii
US20110236900A1 (en) 2008-11-27 2011-09-29 Riken Novel muts protein and method for determing mutation using the same
CN104215756B (zh) 2008-12-25 2016-11-23 环球生物研究株式会社 生物相关物质的测定系统
GB0910302D0 (en) * 2009-06-15 2009-07-29 Lumora Ltd Nucleic acid amplification
EP2746395B1 (de) 2011-09-08 2017-11-29 Kabushiki Kaisha DNAFORM Primer-set, verfahren zur amplifizierung einer nukleinsäuresequenz damit und verfahren zur erkennung von mutierter nukleinsäure damit
WO2013065574A1 (ja) 2011-10-31 2013-05-10 栄研化学株式会社 標的核酸の検出法
EP2925878A1 (de) 2012-11-28 2015-10-07 Abwiz Bio Inc. Herstellung von genspezifischen templates zur verwendung in der einzelprimeramplifikation
US9677981B2 (en) 2013-03-15 2017-06-13 3M Innovative Properties Company Sample concentrator and method of use
CN105722977A (zh) 2013-10-30 2016-06-29 绿色生活生物技术有限责任公司 用于柑橘绿化枯萎病的发病定量系统和治疗方法
WO2016011280A1 (en) 2014-07-16 2016-01-21 Tangen Biosciences, Inc. Isothermal methods for amplifying nucleic acid samples
US11559801B2 (en) 2014-11-03 2023-01-24 Tangen Biosciences, Inc. Apparatus and method for cell, spore, or virus capture and disruption
JP6605238B2 (ja) * 2014-12-19 2019-11-13 国立大学法人 長崎大学 ザイールエボラウイルス検出用プライマーセット、アッセイキットおよび増幅方法
WO2016098892A1 (ja) * 2014-12-19 2016-06-23 国立大学法人 長崎大学 ザイールエボラウイルス検出用プライマーセット、アッセイキットおよび増幅方法
RU2017137788A (ru) 2015-03-30 2019-04-30 Гринлайт Байосайенсис, Инк. Бесклеточное получение рибонуклеиновой кислоты
WO2017212904A1 (ja) * 2016-06-06 2017-12-14 国立大学法人 宮崎大学 複数のプライマーセットを組み合わせたｌａｍｐ法を用いたアフリカ豚コレラウイルスの迅速検出法
WO2018209092A1 (en) * 2017-05-10 2018-11-15 Board Of Regents, The University Of Texas System Methods and devices related to amplifying nucleic acid at a variety of temperatures
JP7176682B2 (ja) 2018-02-22 2022-11-22 佐藤製薬株式会社 白癬菌の遺伝子をｌａｍｐ法により検出するためのプライマーセット及びそれを含むキット並びにそれらを用いて白癬菌を検出する方法
CN109658982B (zh) * 2018-12-25 2020-06-19 人和未来生物科技（长沙）有限公司 一种用于基因测序的引物设计方法及系统
US12590324B2 (en) * 2019-01-14 2026-03-31 Camena Bioscience Limited Compositions and methods for template-free geometric enzymatic nucleic acid synthesis
EP3911765A1 (de) 2019-01-15 2021-11-24 3M Innovative Properties Company Schleifenvermittelte isotherme amplifikationsprimer für den nachweis von shiga-toxin-produzierenden e. coli (stec)
SG10201910254YA (en) 2019-11-04 2021-06-29 Denka Company Ltd Nucleic Acid Detection Method Using Lamp And Probe Detection
CN110878367A (zh) * 2019-12-05 2020-03-13 华南农业大学 一种可检测snp的新型cpa方法、引物组和试剂盒
WO2021172370A1 (ja) 2020-02-27 2021-09-02 栄研化学株式会社 一本鎖ｒｎａウイルスを検出する方法
JP7313537B2 (ja) 2020-03-05 2023-07-24 栄研化学株式会社 コロナウイルス（ＳＡＲＳ－ＣｏＶ－２）の検出方法
KR102814480B1 (ko) 2020-03-13 2025-05-29 어-오 랩스 인코포레이션 표적 핵산을 검출하기 위한 루프형 프라이머 및 루프-드-루프 방법
WO2021224355A1 (en) 2020-05-05 2021-11-11 Genomtec Sa Diagnostic primers, kits and methods for viral detection
CA3186580A1 (en) 2020-06-12 2021-12-16 Sherlock Biosciences, Inc. Crispr-based sars-cov-2 detection
CN116075596A (zh) 2020-08-07 2023-05-05 牛津纳米孔科技公开有限公司 鉴定核酸条形码的方法
CN112553300A (zh) * 2020-10-15 2021-03-26 德歌生物技术(山东)有限公司 引物设计方法、引物及等温扩增核酸片段的方法
EP3992300A1 (de) 2020-10-30 2022-05-04 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk Onderzoek TNO Probenvorbehandlung zur isothermen amplifikation
WO2022155246A1 (en) 2021-01-12 2022-07-21 Definitive Biotechnologies Llc Device and method for detecting nucleic acids in biological samples
EP4291678A1 (de) 2021-02-09 2023-12-20 Sherlock Biosciences, Inc. Nukleinsäureamplifikation unter verwendung von promotorprimern
US11788129B2 (en) 2021-02-23 2023-10-17 Industrial Technology Research Institute Nucleic acid detection kit and nucleic acid detection method
PL437280A1 (pl) 2021-03-12 2022-09-19 Genomtec Spółka Akcyjna Zestaw starterów do powielania, sposób wykrywania infekcji bakteryjnej przenoszonej drogą płciową oraz zestaw do wykrywania infekcji
PL437660A1 (pl) 2021-04-22 2022-10-24 Genomtec Spółka Akcyjna Zestaw starterów, skład reagentów oraz metoda wykrywania bakterii Staphylococcus aureus opornej na metycylinę (MRSA)
CN113201583B (zh) * 2021-04-29 2022-02-08 国科宁波生命与健康产业研究院 恒温条件下合成核酸的方法及试剂盒和应用
EP4105327A4 (de) * 2021-04-29 2023-01-18 Ningbo Institute of Life and Health Industry University of Chinese Academy of Sciences Verfahren zur herstellung von nukleinsäuren mit konstanter temperatur und kit und verwendung davon
JP2025500496A (ja) 2021-12-24 2025-01-09 エフ． ホフマン－ラ ロシュ アーゲー Ｌａｍｐ増幅産物の改良された検出
WO2025009968A1 (en) 2023-07-03 2025-01-09 Erasmus University Medical Center Rotterdam Methods for specific quantitation of the inducible hiv reservoir
EP4488391A1 (de) 2023-07-04 2025-01-08 Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO Verfahren und mittel zum nachweis von legionella
GB202501167D0 (en) 2025-01-27 2025-03-12 Genomtec Sa A method for detecting nucleotide varients in a nucleic acid sequence

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6743605B1 (en) * 1998-06-24 2004-06-01 Enzo Life Sciences, Inc. Linear amplification of specific nucleic acid sequences
EP1020534B2 (de) 1998-11-09 2011-01-05 Eiken Kagaku Kabushiki Kaisha Verfahren zur synthese von nukleinsäuren
KR100612551B1 (ko) 1999-11-08 2006-08-11 에이켄 카가꾸 가부시끼가이샤 핵산의 합성방법
WO2001034838A1 (en) * 1999-11-08 2001-05-17 Eiken Kagaku Kabushiki Kaisha Method of detecting variation or polymorphism
CN100422323C (zh) * 2000-04-07 2008-10-01 荣研化学株式会社 使用双链核酸为模板扩增核酸的方法
DE60139331D1 (de) * 2000-09-19 2009-09-03 Eiken Chemical Verfahren zur polynukleotidsynthese

Also Published As

Publication number Publication date
CN1474870A (zh) 2004-02-11
US7374913B2 (en) 2008-05-20
ES2327712T3 (es) 2009-11-03
US7846695B2 (en) 2010-12-07
US20080213842A1 (en) 2008-09-04
JP2012085652A (ja) 2012-05-10
JP4918210B2 (ja) 2012-04-18
EP2031058A1 (de) 2009-03-04
EP1327679A1 (de) 2003-07-16
ES2390242T3 (es) 2012-11-07
JPWO2002024902A1 (ja) 2004-01-29
HK1055445A1 (en) 2004-01-09
EP1327679A4 (de) 2005-06-01
US20040038253A1 (en) 2004-02-26
EP1327679B1 (de) 2009-07-22
US20080213790A1 (en) 2008-09-04
CN1222614C (zh) 2005-10-12
DE60139331D1 (de) 2009-09-03
EP2031058B1 (de) 2012-07-18
AU2001288065A1 (en) 2002-04-02
US7851186B2 (en) 2010-12-14
WO2002024902A1 (en) 2002-03-28

Similar Documents

Publication Publication Date Title
DE60139331D1 (de) Verfahren zur polynukleotidsynthese
DE60020340D1 (de) Syntheseverfahren zum ökonomischen aufbau langer dna-sequenzen und zusammensetzungen hierfür
DK1828381T3 (da) Templatedirigeret split-and-mix-syntese af småmolekylebiblioteker
DE69940623D1 (de) Prozess zur Synthetisierung von Nukleinsäure
ATE264268T1 (de) Verfahren zur herstellung von zsm-5 und zsm-11
UA83910C2 (ru) Способ получения 5-гидрокси-4-тиометилпиразольного соединения
ATE221893T1 (de) Verfahren zur herstellung von acylphosphinen und derivaten
ATE517857T1 (de) Herstellung von 4-phenylbutansäure
ATE323703T1 (de) Synthese von verbindungen die zur herstellung von ketorolac dienen
ATE318803T1 (de) Verfahren zur herstellung von laktonen
ATE525341T1 (de) Verfahren zur herstellung von 1-acetyl-1- chlorcyclopropan
DE602004012151D1 (de) Verfahren zur herstellung von chlorsulfonylisocyanat
HUP0100943A2 (hu) Eljárás poliamidok előállítására
DE3886501D1 (de) Verfahren zur Synthese von N,N-Dialkylhydroxylaminen.
ATE469141T1 (de) Verfahren zur herstellung von substituierten thiophensulfonylisocyanaten
ATE46190T1 (de) Gerbstoff und verfahren zu seiner herstellung.
ATE384730T1 (de) Verfahren zur herstellung von palladium(0)- haltigen verbindungen
DE60230366D1 (de) Verfahren zur Herstellung eines optisch aktiven Amids ausgehend von einem alpha, beta-ungesättigtem Amid Derivat in Anwesenheit eines optisch aktiven Übergangsmetallkomplexes, der eine Phosphin-Phosphoran Verbindung und Rhodium enthält
DE60219341D1 (de) Verfahren zur hydrierung von aceton
DE60203187D1 (de) Verfahren zur herstellung von di tert.-butyl-cis-1-propenylphosphonat
DE69812858D1 (de) Verfahren zur Herstellung von (R)-3-Hydroxy-4-Butyrolacton, nützlich für die Herstellung von (R)-Carnitin
DE60218533D1 (de) Nukleotidsequenzen mit aktivität zur steuerung der translationseffizienz und deren nutzung
ATE527213T1 (de) Verfahren zur herstellung von ammoniumpolythiomolybdat
DE60230740D1 (de) Unkatalysierte additionsreaktionen
ATE458723T1 (de) Verfahren zur herstellung von 4,6-dichlor-5- fluorpyrimidin

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties