ATE437886T1 - Verfahren und reagentien zum nachweis von endotoxin - Google Patents

Verfahren und reagentien zum nachweis von endotoxin

Info

Publication number
ATE437886T1
ATE437886T1 AT02768293T AT02768293T ATE437886T1 AT E437886 T1 ATE437886 T1 AT E437886T1 AT 02768293 T AT02768293 T AT 02768293T AT 02768293 T AT02768293 T AT 02768293T AT E437886 T1 ATE437886 T1 AT E437886T1
Authority
AT
Austria
Prior art keywords
reagents
methods
detecting endotoxin
endotoxin
factor
Prior art date
Application number
AT02768293T
Other languages
English (en)
Inventor
Lin Chen
Michael Pepe
Original Assignee
Lonza Walkersville Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23162060&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE437886(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lonza Walkersville Inc filed Critical Lonza Walkersville Inc
Application granted granted Critical
Publication of ATE437886T1 publication Critical patent/ATE437886T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/579—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving limulus lysate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/50—Lipopolysaccharides; LPS

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
AT02768293T 2001-06-28 2002-06-28 Verfahren und reagentien zum nachweis von endotoxin ATE437886T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30112501P 2001-06-28 2001-06-28
PCT/US2002/020395 WO2003002976A2 (en) 2001-06-28 2002-06-28 Methods and reagents for detecting endotoxin

Publications (1)

Publication Number Publication Date
ATE437886T1 true ATE437886T1 (de) 2009-08-15

Family

ID=23162060

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02768293T ATE437886T1 (de) 2001-06-28 2002-06-28 Verfahren und reagentien zum nachweis von endotoxin

Country Status (14)

Country Link
US (2) US20040235080A1 (de)
EP (1) EP1409984B2 (de)
JP (2) JP2005500520A (de)
CN (1) CN100390193C (de)
AT (1) ATE437886T1 (de)
AU (1) AU2002330860C1 (de)
BR (1) BRPI0210681B8 (de)
CY (1) CY1109554T1 (de)
DE (1) DE60233142D1 (de)
DK (1) DK1409984T4 (de)
ES (1) ES2329664T5 (de)
MX (1) MXPA03012032A (de)
PT (1) PT1409984E (de)
WO (1) WO2003002976A2 (de)

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CN1318848C (zh) * 2003-11-26 2007-05-30 中国科学院大连化学物理研究所 一种用于细菌内毒素鲎试验检测法的缓冲液及其制备方法
JP5495490B2 (ja) * 2004-05-07 2014-05-21 アレス トレーディング エスエイ ランダム共重合体を用いる疾患の治療方法
JP2008518625A (ja) * 2004-11-05 2008-06-05 ダウ・アグロサイエンス・エル・エル・シー 細胞の低温保存
US20060223074A1 (en) * 2005-04-05 2006-10-05 Bunch Thomas A Spotting compositions and methods of use thereof
WO2007047498A2 (en) * 2005-10-14 2007-04-26 The Regents Of The University Of California Formation and encapsulation of molecular bilayer and monolayer membranes
US9233846B2 (en) * 2005-10-14 2016-01-12 The Regents Of The University Of California Formation and encapsulation of molecular bilayer and monolayer membranes
US20090208995A1 (en) * 2006-07-07 2009-08-20 Seikagaku Corporation Pro-clotting enzyme, and method for detection of endotoxin or (1-3)-beta-d-glucan using the same
CA2667890C (en) 2006-10-31 2015-01-27 Surmodics Pharmaceuticals, Inc. Spheronized polymer particles
EP2219620B1 (de) * 2007-11-13 2017-07-19 Surmodics, Inc. Viskose terpolymere als arzneiabgabe-plattform
EP2293921A4 (de) * 2008-05-22 2013-05-22 Univ California Membranvorläufer und daraus hergestellte membrane
US7846678B2 (en) * 2008-08-18 2010-12-07 BioDtech, Inc. Enhancing endotoxin detection
AU2009308841B2 (en) 2008-10-29 2014-07-17 T2 Biosystems, Inc. NMR detection of coagulation time
US20100168807A1 (en) * 2008-12-23 2010-07-01 Burton Kevin W Bioactive terpolymer compositions and methods of making and using same
US8974808B2 (en) 2008-12-23 2015-03-10 Surmodics, Inc. Elastic implantable composites and implants comprising same
US8951546B2 (en) * 2008-12-23 2015-02-10 Surmodics Pharmaceuticals, Inc. Flexible implantable composites and implants comprising same
US9480643B2 (en) 2008-12-23 2016-11-01 Surmodics Pharmaceuticals, Inc. Implantable composites and implants comprising same
US9415197B2 (en) * 2008-12-23 2016-08-16 Surmodics, Inc. Implantable suction cup composites and implants comprising same
EP2446018B1 (de) 2009-06-26 2017-01-18 Charles River Laboratories, Inc. Wärmebehandelte limulus-amebocyt-lysaten
WO2011085047A1 (en) 2010-01-05 2011-07-14 The Regents Of The University Of California Droplet bilayer formation using throughput liquid handling techniques
WO2011146463A2 (en) * 2010-05-17 2011-11-24 BioDtech, Inc. Enhancing endotoxin detection
EP2611868B1 (de) 2010-08-30 2020-01-08 Surmodics Pharmaceuticals, Inc. Biologisch abbaubare terpolymere und terpolymermischungen als haftkleber
WO2012118800A2 (en) * 2011-02-28 2012-09-07 BioDtech, Inc. Enhancing endotoxin detection
US20140024062A1 (en) * 2011-02-28 2014-01-23 Seikagaku Corporation Agent for measuring endotoxin
WO2013010080A1 (en) 2011-07-13 2013-01-17 T2 Biosystems, Inc. Nmr methods for monitoring blood clot formation
WO2013043858A1 (en) 2011-09-21 2013-03-28 T2 Biosystems, Inc. Nmr methods for endotoxin analysis
EP2578207A3 (de) 2011-10-05 2015-10-07 Jacob J. Schmidt Maskierungsvorrichtung, die Automatisierung und Lösungsaustausch in sessilen Fetttröpfchen-Doppelschichten ermöglicht
CU24073B1 (es) 2011-12-27 2015-01-29 Ct De Investigación Y Desarrollo De Medicamentos Cidem COMPOSICIÓN A PARTIR DE EXTRACTO DE HEMOCITOS DE LANGOSTA PARA LA DETECCIÓN DE LIPOPOLISACÁRIDOS, PEPTIDOGLICANOS Y 1,3-ß-D-GLUCANOS
CN103290042A (zh) * 2012-02-27 2013-09-11 上海拜生生物科技有限公司 内毒素检测及去除关键分子中国鲎c因子克隆和序列分析
CN103290041A (zh) * 2012-02-27 2013-09-11 上海拜生生物科技有限公司 中国鲎c因子原核及昆虫杆状病毒重组表达载体的构建
CN103290054A (zh) * 2012-02-27 2013-09-11 上海拜生生物科技有限公司 应用昆虫细胞表达重组的中国鲎c因子
EP2740791A1 (de) 2012-12-05 2014-06-11 MicroCoat Biotechnologie GmbH Verfahren für die rekombinante Herstellung von Pfeilschwanzkrebs-Faktor-C-Protein in Protozoen
EP2929047A4 (de) 2012-12-07 2016-08-03 T2 Biosystems Inc Verfahren zur überwachung der formierung von dichten gerinnseln
CN108642030A (zh) 2012-12-10 2018-10-12 生化学工业株式会社 新重组因子c、其制造方法、及内毒素的测定法
CN104356211B (zh) * 2014-09-22 2017-08-29 山东信得科技股份有限公司 一种应用Triton X‑114和尿囊素去除重组蛋白质溶液中内毒素的方法
US20190241629A1 (en) 2016-10-18 2019-08-08 Seikagaku Corporation Recombinant proteins derived from genus limulus, and dna molecules encoding same
CN111077307B (zh) * 2018-10-21 2022-08-23 厦门鲎试剂生物科技股份有限公司 一种用革兰氏阴性细菌感染快速检测脓毒病的新方法
JP7349104B2 (ja) * 2019-11-13 2023-09-22 株式会社島津製作所 ベロ毒素の検出方法
EP4137817A4 (de) 2020-04-16 2024-08-07 Kikkoman Corporation Hydrolase verwendendes verfahren zur spurenstoffmessung
JPWO2024204498A1 (de) 2023-03-30 2024-10-03
WO2024204497A1 (ja) 2023-03-30 2024-10-03 キッコーマン株式会社 組換えタンパク質
CN119881319B (zh) * 2024-12-04 2025-11-28 苏州鲎源生物科技有限公司 一种重组鲎三因子试剂及试剂盒

Family Cites Families (12)

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CA1159754A (en) * 1980-06-27 1984-01-03 Roxane N. Dikeman Process for preparing limulus lysate
US4322217A (en) * 1980-06-27 1982-03-30 Mallinckrodt, Inc. Process for preparing Limulus lysate
JPH03187378A (ja) * 1989-12-16 1991-08-15 Taiyo Fishery Co Ltd 酵素前駆体ファクターｃの調整方法及びその調整試薬
JP3524120B2 (ja) * 1992-05-08 2004-05-10 生化学工業株式会社 前処理剤、前処理方法、前処理された試料による測定法、測定用キット及び試料の判定方法
JP3402476B2 (ja) * 1992-08-24 2003-05-06 生化学工業株式会社 リポ多糖結合性タンパク質及びその製造法
JP3429036B2 (ja) * 1993-09-30 2003-07-22 生化学工業株式会社 エンドトキシンの特異的測定剤
US5716834A (en) * 1994-08-19 1998-02-10 National University Of Singapore Cloned factor C cDNA of the Singapore horseshoe crab, Carcinoscorpius rotundicauda and purification of factor C proenzyme
JP3869094B2 (ja) * 1996-10-21 2007-01-17 生化学工業株式会社 エンドトキシンの測定方法
EP0837330B1 (de) 1996-10-21 2005-08-24 Seikagaku Corporation Verfahren zur Bestimmung von Endotoxin
WO1999015676A1 (en) * 1997-09-19 1999-04-01 National University Of Singapore A novel generation of cloned horseshoe crab recombinant factor c for detection and removal of endotoxin
JP3957386B2 (ja) * 1998-01-08 2007-08-15 生化学工業株式会社 昆虫体液反応性物質の特異的測定剤及び測定方法
WO2001027289A2 (en) * 1999-10-15 2001-04-19 National University Of Singapore Recombinant proteins and peptides for endotoxin biosensors, endotoxin removal, and anti-microbial and anti-endotoxin therapeutics

Also Published As

Publication number Publication date
US20040235080A1 (en) 2004-11-25
EP1409984A2 (de) 2004-04-21
ES2329664T5 (es) 2013-08-28
CY1109554T1 (el) 2014-08-13
DE60233142D1 (de) 2009-09-10
CN100390193C (zh) 2008-05-28
AU2002330860B2 (en) 2008-12-04
US6849426B2 (en) 2005-02-01
BR0210681A (pt) 2004-09-21
DK1409984T3 (da) 2009-11-16
CN1529711A (zh) 2004-09-15
EP1409984A4 (de) 2006-07-19
BRPI0210681B8 (pt) 2021-07-27
JP5039729B2 (ja) 2012-10-03
JP2009150903A (ja) 2009-07-09
EP1409984B2 (de) 2013-04-10
PT1409984E (pt) 2009-10-29
ES2329664T3 (es) 2009-11-30
BRPI0210681B1 (pt) 2016-03-29
JP2005500520A (ja) 2005-01-06
AU2002330860C1 (en) 2009-05-14
US20030054432A1 (en) 2003-03-20
DK1409984T4 (da) 2013-07-08
WO2003002976A2 (en) 2003-01-09
WO2003002976A3 (en) 2003-05-15
EP1409984B1 (de) 2009-07-29
MXPA03012032A (es) 2005-07-01

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