ATE438097T1 - Gut reproduzierbares agglutinations- immunoassayverfahren und reagenzien - Google Patents
Gut reproduzierbares agglutinations- immunoassayverfahren und reagenzienInfo
- Publication number
- ATE438097T1 ATE438097T1 AT01958575T AT01958575T ATE438097T1 AT E438097 T1 ATE438097 T1 AT E438097T1 AT 01958575 T AT01958575 T AT 01958575T AT 01958575 T AT01958575 T AT 01958575T AT E438097 T1 ATE438097 T1 AT E438097T1
- Authority
- AT
- Austria
- Prior art keywords
- agglutination
- monomer
- carrier particles
- insoluble carrier
- antigenic substance
- Prior art date
Links
- 230000004520 agglutination Effects 0.000 title abstract 5
- 238000003018 immunoassay Methods 0.000 title abstract 3
- 239000003153 chemical reaction reagent Substances 0.000 title abstract 2
- 230000000890 antigenic effect Effects 0.000 abstract 3
- 239000000178 monomer Substances 0.000 abstract 3
- 239000002245 particle Substances 0.000 abstract 3
- 239000000126 substance Substances 0.000 abstract 3
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 abstract 3
- NJNWCIAPVGRBHO-UHFFFAOYSA-N 2-hydroxyethyl-dimethyl-[(oxo-$l^{5}-phosphanylidyne)methyl]azanium Chemical group OCC[N+](C)(C)C#P=O NJNWCIAPVGRBHO-UHFFFAOYSA-N 0.000 abstract 2
- SOGAXMICEFXMKE-UHFFFAOYSA-N Butylmethacrylate Chemical compound CCCCOC(=O)C(C)=C SOGAXMICEFXMKE-UHFFFAOYSA-N 0.000 abstract 2
- 238000006116 polymerization reaction Methods 0.000 abstract 2
- ZSZRUEAFVQITHH-UHFFFAOYSA-N 2-(2-methylprop-2-enoyloxy)ethyl 2-(trimethylazaniumyl)ethyl phosphate Chemical compound CC(=C)C(=O)OCCOP([O-])(=O)OCC[N+](C)(C)C ZSZRUEAFVQITHH-UHFFFAOYSA-N 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 229920001577 copolymer Polymers 0.000 abstract 1
- 229920001519 homopolymer Polymers 0.000 abstract 1
- 239000004816 latex Substances 0.000 abstract 1
- 229920000126 latex Polymers 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F230/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing phosphorus, selenium, tellurium or a metal
- C08F230/02—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing phosphorus, selenium, tellurium or a metal containing phosphorus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
- G01N33/545—Synthetic resin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
- G01N33/721—Haemoglobin
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/961—Chemistry: molecular biology and microbiology including a step of forming, releasing, or exposing the antigen or forming the hapten-immunogenic carrier complex or the antigen per se
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000259964 | 2000-08-29 | ||
| PCT/JP2001/007385 WO2002018953A1 (en) | 2000-08-29 | 2001-08-28 | Highly reproducible agglutination immunoassay method and reagents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE438097T1 true ATE438097T1 (de) | 2009-08-15 |
Family
ID=18748057
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01958575T ATE438097T1 (de) | 2000-08-29 | 2001-08-28 | Gut reproduzierbares agglutinations- immunoassayverfahren und reagenzien |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7166476B2 (de) |
| EP (1) | EP1314982B1 (de) |
| JP (1) | JP4733335B2 (de) |
| KR (1) | KR100778102B1 (de) |
| CN (1) | CN1215333C (de) |
| AT (1) | ATE438097T1 (de) |
| AU (1) | AU2001280210A1 (de) |
| CA (1) | CA2420770C (de) |
| DE (1) | DE60139408D1 (de) |
| WO (1) | WO2002018953A1 (de) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4680361B2 (ja) * | 2000-09-22 | 2011-05-11 | 一彦 石原 | 分離・回収方法 |
| DE60215635T2 (de) * | 2001-04-26 | 2009-07-09 | Nof Corp. | Inhibitoren zur Inhibierung unspezifischer Hybridisierung, klinische Diagnosereagenzien und ein Verfahren zur klinischen Analyse |
| JP4577747B2 (ja) * | 2001-06-05 | 2010-11-10 | 和光純薬工業株式会社 | 免疫学的測定法用凝集促進剤 |
| JP4512492B2 (ja) * | 2002-12-10 | 2010-07-28 | パナソニック株式会社 | 免疫反応測定方法およびそれに用いる免疫反応測定用試薬 |
| GB0229747D0 (en) * | 2002-12-20 | 2003-01-29 | Axis Shield Asa | Assay |
| JP4241301B2 (ja) * | 2003-09-30 | 2009-03-18 | 和光純薬工業株式会社 | 免疫学的測定用試薬 |
| JP3809177B2 (ja) * | 2004-05-24 | 2006-08-16 | 株式会社資生堂 | アフィニティー粒子及びアフィニティー分離方法 |
| AU2005203321A1 (en) * | 2004-08-03 | 2006-02-23 | Axis-Shield Diagnostics Limited | Assay |
| EP1717585B1 (de) * | 2005-04-28 | 2013-01-16 | FUJIFILM Corporation | Mikrochip und Analyseverfahren unter Verwendung desselben |
| JP4629563B2 (ja) * | 2005-12-07 | 2011-02-09 | 積水メディカル株式会社 | 抗リン脂質抗体測定試薬 |
| EP1956373B1 (de) * | 2005-12-07 | 2017-01-25 | Sekisui Medical Co., Ltd. | Verfharen zum nachweis eines antikörpers gegen treponema pallidum |
| KR101550253B1 (ko) * | 2007-10-22 | 2015-09-04 | 알프레사 파마 가부시키가이샤 | 면역학적 미소 입자의 응집 반응을 사용하는 검체의 아크롤레인 부가체의 측정 방법 및 측정용 키트 |
| JP2008058334A (ja) * | 2007-11-21 | 2008-03-13 | Towns:Kk | イムノクロマトグラフィー用展開溶媒、測定法およびキット |
| WO2011039775A1 (en) * | 2009-09-30 | 2011-04-07 | Department Of Biotechnology | A modified method of agglutination to detect infections caused by microorganisms |
| CN101819202B (zh) * | 2010-05-06 | 2012-12-26 | 上海太阳生物技术有限公司 | D-二聚体(D-Dimer)测定试剂盒(胶乳免疫比浊法) |
| CN102000067B (zh) * | 2010-09-30 | 2013-04-03 | 苏州中药研究所 | 一种蛇床子素在制备防治肺纤维化药物中的应用 |
| JP6107653B2 (ja) * | 2011-06-07 | 2017-04-05 | 和光純薬工業株式会社 | 凝集促進剤 |
| US9383356B2 (en) * | 2012-09-27 | 2016-07-05 | Sekisui Medical Co., Ltd. | Latex particles for particle agglutination assay |
| EP2947458A4 (de) * | 2013-01-16 | 2016-08-10 | Fujirebio Kk | Verfahren zur immunologischen bestimmung von hämoglobin-a1c in proben |
| FR3045834B1 (fr) * | 2015-12-21 | 2021-03-05 | Biomerieux Sa | Diluant de reactifs pour immunoessai |
| TWI800483B (zh) * | 2016-05-30 | 2023-05-01 | 日商榮研化學股份有限公司 | 抗人類血紅素單株抗體或抗體套組、抗人類血紅素單株抗體固定化不可溶性載體粒子、及使用其等之測定試劑或測定方法 |
| SG11202103027UA (en) * | 2018-09-28 | 2021-04-29 | Sekisui Medical Co Ltd | Glycated hemoglobin (%) assay method |
| JP7182724B2 (ja) * | 2019-02-15 | 2022-12-02 | シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレイテッド | 患者の液体試験サンプル中の糖化ヘモグロビンパーセントを決定するためのキャリブレーターおよびコントロール |
| JP7436838B2 (ja) * | 2020-05-20 | 2024-02-22 | 藤倉化成株式会社 | 抗体－デンドリマー複合体を用いるヘモグロビンＡ１ｃの測定方法 |
| CN113406323B (zh) * | 2021-06-18 | 2022-03-22 | 上海奥普生物医药股份有限公司 | 一种胶乳免疫比浊第二试剂、含其的组合及其制备方法 |
| CN119816734A (zh) | 2022-10-06 | 2025-04-11 | 积水医疗株式会社 | 非特异反应抑制剂、非特异反应抑制剂的使用方法、非特异反应抑制方法、生化测定用试剂、检体预处理液和生化测定用试剂盒 |
| CN120530323A (zh) * | 2022-12-27 | 2025-08-22 | 深圳迈瑞生物医疗电子股份有限公司 | 用于检测糖化血红蛋白的试剂、检测方法及应用 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS546325B2 (de) | 1974-05-10 | 1979-03-27 | ||
| JPS6047552B2 (ja) * | 1976-04-08 | 1985-10-22 | 栄研化学株式会社 | Ｃ反応性蛋白質測定用試薬 |
| JPS5924387B2 (ja) * | 1977-07-27 | 1984-06-08 | 栄研化学株式会社 | リウマチ因子検出用試薬゜ |
| JPS5811575A (ja) | 1981-07-13 | 1983-01-22 | Hohnen Oil Co Ltd | 耐水性接着剤 |
| JPS58154591A (ja) | 1982-03-09 | 1983-09-14 | Tadao Nakaya | リン脂質類似モノマ−の製造法 |
| US4609630A (en) * | 1983-03-23 | 1986-09-02 | Yanovsky Jorge F | Method for improving the specificity of immunoassays |
| JPS61159166A (ja) * | 1984-12-29 | 1986-07-18 | Nitto Electric Ind Co Ltd | 免疫学的診断試薬 |
| JPS61274261A (ja) | 1985-05-30 | 1986-12-04 | Nitto Electric Ind Co Ltd | 免疫学的診断試薬 |
| JPH0668492B2 (ja) | 1986-03-20 | 1994-08-31 | 日立化成工業株式会社 | リウマチ因子の定量法 |
| JPS62259063A (ja) * | 1986-05-02 | 1987-11-11 | Oriental Yeast Co Ltd | Ｃ−反応性蛋白質の定量方法 |
| JP2677753B2 (ja) * | 1993-07-22 | 1997-11-17 | 株式会社エスアールエル | 凝集イムノアッセイ法 |
| KR100226093B1 (ko) | 1995-04-03 | 1999-10-15 | 우노 마사야스 | 포스포릴콜린기 함유 중합체 수용액의 제조방법 및 포스포릴콜린기 함유중합체 수용액(method for producing aqueous solution of polymer having phosphorylcholing groups and aqueous solution of polymer having phosphorylcholine groups) |
| US5977257A (en) * | 1995-04-28 | 1999-11-02 | Nof Corporation | Polymer material, medical material and liquid high molecular composition |
| JP2654932B2 (ja) | 1995-06-16 | 1997-09-17 | オリエンタル酵母工業株式会社 | Ｃ−反応性蛋白質測定用試薬 |
| JP3782851B2 (ja) | 1996-07-31 | 2006-06-07 | 日本油脂株式会社 | 蛋白質の安定化方法および組成物 |
| JP3884510B2 (ja) | 1996-10-14 | 2007-02-21 | 日本油脂株式会社 | 固定化免疫学的活性物質の保存時安定化方法 |
-
2001
- 2001-08-28 AT AT01958575T patent/ATE438097T1/de not_active IP Right Cessation
- 2001-08-28 AU AU2001280210A patent/AU2001280210A1/en not_active Abandoned
- 2001-08-28 EP EP01958575A patent/EP1314982B1/de not_active Expired - Lifetime
- 2001-08-28 WO PCT/JP2001/007385 patent/WO2002018953A1/ja not_active Ceased
- 2001-08-28 CA CA2420770A patent/CA2420770C/en not_active Expired - Lifetime
- 2001-08-28 US US10/363,038 patent/US7166476B2/en not_active Expired - Lifetime
- 2001-08-28 CN CNB018148476A patent/CN1215333C/zh not_active Expired - Lifetime
- 2001-08-28 DE DE60139408T patent/DE60139408D1/de not_active Expired - Lifetime
- 2001-08-28 KR KR1020037002767A patent/KR100778102B1/ko not_active Expired - Lifetime
- 2001-08-28 JP JP2002523622A patent/JP4733335B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002018953A1 (en) | 2002-03-07 |
| CA2420770A1 (en) | 2002-03-07 |
| KR20030029860A (ko) | 2003-04-16 |
| KR100778102B1 (ko) | 2007-11-27 |
| CN1215333C (zh) | 2005-08-17 |
| JP4733335B2 (ja) | 2011-07-27 |
| DE60139408D1 (de) | 2009-09-10 |
| CN1449495A (zh) | 2003-10-15 |
| EP1314982A4 (de) | 2006-06-28 |
| US7166476B2 (en) | 2007-01-23 |
| CA2420770C (en) | 2010-05-25 |
| EP1314982A1 (de) | 2003-05-28 |
| AU2001280210A1 (en) | 2002-03-13 |
| US20030166302A1 (en) | 2003-09-04 |
| EP1314982B1 (de) | 2009-07-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE438097T1 (de) | Gut reproduzierbares agglutinations- immunoassayverfahren und reagenzien | |
| ATE244406T1 (de) | Verfahren zur bestimmung von mehr als einem immunologischen liganden und bestimmungsreagenz sowie satz dafuer | |
| ATE228247T1 (de) | Testreagentien und testvorrichtungen | |
| KR890702038A (ko) | 인간 혈청에서의 hiv 항원 검출용 효소 면역 분석법 | |
| EP0335244A3 (en) | Solid-phase analytical device and method for using same | |
| FI90799C (fi) | Immunologisia määritysmenetelmiä ja niissä käytettävä reagenssi | |
| CA2188752A1 (en) | Immunoassay for homocysteine | |
| ATE310956T1 (de) | Festphasenverfahren und testsatz zur antigen- und antikörperprüfung in der blutgruppen-serologie | |
| DK196282A (da) | Fremgangsmaade samt kit til bestemmelse af antistoffer mod oploeselige antigener | |
| RU2001115777A (ru) | Метод обнаружения антител к трансглутаминазе для применения в диагностике целиакии | |
| CA2349274A1 (en) | Assay for anti transglutaminase antibodies | |
| CA2285219A1 (en) | Detection of low level analytes in samples | |
| DE69819643D1 (de) | Zwei-Inkubations mit markiertem Antigen verwendenes Immunoassay | |
| DE59712595D1 (de) | Homogene Nachweisverfahren zur Bestimmung von Subpopulationen eines Analyten | |
| SE9502024D0 (sv) | Pathogen assay method | |
| DE60137792D1 (de) | Immunologisches verfahren | |
| CA2499355A1 (en) | Compositions, methods and kits for detection of an antigen on a cell and in a biological mixture | |
| ATE405830T1 (de) | Verfahren zur beseitigung von störungen in immunochromatographischen assays | |
| RU2004139110A (ru) | Тест-система в виде биологического чипа, основанная на реакциях взаимодействия антитела с антигеном, и ее применение | |
| US20100197042A1 (en) | Reagent and method for immunological analysis | |
| ATE174688T1 (de) | Verfahren zur bestimmung von antigenen oder antikörpern in gegenwart eines immunkomplexes | |
| KR930703613A (ko) | 시료 희석물중 과산화물 디스뮤타제의 용도 | |
| DE69830174D1 (de) | Antikörper und sonstige bindungsmoleküle gegen hepatitis b virusantigene | |
| KR890702034A (ko) | 자체 완비된 다중-면역 분석 진단시스템 | |
| DK0433629T3 (da) | Fremgangsmåde til kvalitativ og kvantitativ bestemmelse af antistoffer mod bakterielle antigener ved hjælp af den fotometriske måling af agglutination |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |