ATE438717T1 - Dp-75 kodierende dna und verfahren zu ihrer verwendung - Google Patents

Dp-75 kodierende dna und verfahren zu ihrer verwendung

Info

Publication number
ATE438717T1
ATE438717T1 AT97927980T AT97927980T ATE438717T1 AT E438717 T1 ATE438717 T1 AT E438717T1 AT 97927980 T AT97927980 T AT 97927980T AT 97927980 T AT97927980 T AT 97927980T AT E438717 T1 ATE438717 T1 AT E438717T1
Authority
AT
Austria
Prior art keywords
nucleic acid
fragments
present
acid sequence
coding dna
Prior art date
Application number
AT97927980T
Other languages
English (en)
Inventor
David Duhl
Original Assignee
Novartis Vaccines & Diagnostic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Vaccines & Diagnostic filed Critical Novartis Vaccines & Diagnostic
Application granted granted Critical
Publication of ATE438717T1 publication Critical patent/ATE438717T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
AT97927980T 1996-06-05 1997-06-04 Dp-75 kodierende dna und verfahren zu ihrer verwendung ATE438717T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1918096P 1996-06-05 1996-06-05
PCT/US1997/009715 WO1997046680A1 (en) 1996-06-05 1997-06-04 Dna encoding dp. 75 and a process for its use

Publications (1)

Publication Number Publication Date
ATE438717T1 true ATE438717T1 (de) 2009-08-15

Family

ID=21791849

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97927980T ATE438717T1 (de) 1996-06-05 1997-06-04 Dp-75 kodierende dna und verfahren zu ihrer verwendung

Country Status (8)

Country Link
US (1) US6300484B1 (de)
EP (1) EP0938553B1 (de)
JP (4) JP2000513571A (de)
AT (1) ATE438717T1 (de)
AU (1) AU3230797A (de)
DE (1) DE69739524D1 (de)
ES (1) ES2331441T3 (de)
WO (1) WO1997046680A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997046680A1 (en) 1996-06-05 1997-12-11 Chiron Corporation Dna encoding dp. 75 and a process for its use
US7329741B2 (en) 1996-06-05 2008-02-12 Chiron Corporation Polynucleotides that hybridize to DP-75 and their use
JP4707235B2 (ja) * 1999-01-06 2011-06-22 ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド Ｔｉａｍ２（ｔ細胞のリンパ腫の侵襲およびｍｅｔａｓｔａｓｉｓ２）ヌクレオチド交換因子
US20020165145A1 (en) * 2000-09-25 2002-11-07 Meyers Rachel E. 33521, a novel human guanine nucleotide exchange family member and uses thereof
CA2807552A1 (en) 2010-08-06 2012-02-09 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
ES3005233T3 (en) 2010-10-01 2025-03-14 Modernatx Inc Modified nucleosides, nucleotides, and nucleic acids, and uses thereof
JP2014511687A (ja) 2011-03-31 2014-05-19 モデルナ セラピューティクス インコーポレイテッド 工学操作された核酸の送達および製剤
US9464124B2 (en) 2011-09-12 2016-10-11 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
EP2763701B1 (de) 2011-10-03 2018-12-19 Moderna Therapeutics, Inc. Modifizierte nukleoside, nukleotide und nukleinsäuren und verwendungen davon
JP2015501844A (ja) 2011-12-16 2015-01-19 モデルナ セラピューティクス インコーポレイテッドＭｏｄｅｒｎａ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． 修飾ヌクレオシド、ヌクレオチドおよび核酸組成物
US9254311B2 (en) 2012-04-02 2016-02-09 Moderna Therapeutics, Inc. Modified polynucleotides for the production of proteins
WO2013151663A1 (en) 2012-04-02 2013-10-10 modeRNA Therapeutics Modified polynucleotides for the production of membrane proteins
US9572897B2 (en) 2012-04-02 2017-02-21 Modernatx, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
US9283287B2 (en) 2012-04-02 2016-03-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of nuclear proteins
ES2921623T3 (es) 2012-11-26 2022-08-30 Modernatx Inc ARN modificado terminalmente
US8980864B2 (en) 2013-03-15 2015-03-17 Moderna Therapeutics, Inc. Compositions and methods of altering cholesterol levels
WO2015048744A2 (en) 2013-09-30 2015-04-02 Moderna Therapeutics, Inc. Polynucleotides encoding immune modulating polypeptides
KR20160067219A (ko) 2013-10-03 2016-06-13 모더나 세라퓨틱스, 인코포레이티드 저밀도 지단백질 수용체를 암호화하는 폴리뉴클레오타이드

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0348458B1 (de) 1987-11-30 1997-04-09 University Of Iowa Research Foundation Durch modifikationen an der 3'-terminalen phosphodiesterbindung stabilisierte dna moleküle, ihre verwendung als nukleinsäuresonden sowie als therapeutische mittel zur hemmung der expression spezifischer zielgene
JP3348406B2 (ja) 1990-09-13 2002-11-20 デューク ユニバーシティー 酵母におけるｇタンパク質結合受容体の発現
US5422265A (en) * 1990-12-07 1995-06-06 State Of Oregon, Acting By And Through The State Board Of Higher Education On Behalf Of The Oregon Health Sciences University DNA sequence for the human dopamine receptor D4 and expression thereof in mammalian cells
WO1997046680A1 (en) 1996-06-05 1997-12-11 Chiron Corporation Dna encoding dp. 75 and a process for its use
US8174620B2 (en) 2007-11-06 2012-05-08 Microsoft Corporation High definition media content processing

Also Published As

Publication number Publication date
JP2000513571A (ja) 2000-10-17
US6300484B1 (en) 2001-10-09
JP2010017191A (ja) 2010-01-28
ES2331441T3 (es) 2010-01-04
WO1997046680A1 (en) 1997-12-11
DE69739524D1 (de) 2009-09-17
EP0938553B1 (de) 2009-08-05
EP0938553A1 (de) 1999-09-01
AU3230797A (en) 1998-01-05
JP2007289186A (ja) 2007-11-08
JP2011172588A (ja) 2011-09-08

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