ATE440153T1 - Verfahren und kit zur abschätzung der nebenwirkung durch eine paclitaxel-therapie - Google Patents
Verfahren und kit zur abschätzung der nebenwirkung durch eine paclitaxel-therapieInfo
- Publication number
- ATE440153T1 ATE440153T1 AT04799655T AT04799655T ATE440153T1 AT E440153 T1 ATE440153 T1 AT E440153T1 AT 04799655 T AT04799655 T AT 04799655T AT 04799655 T AT04799655 T AT 04799655T AT E440153 T1 ATE440153 T1 AT E440153T1
- Authority
- AT
- Austria
- Prior art keywords
- ims
- seq
- kit
- assessing
- adverse effects
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 229930012538 Paclitaxel Natural products 0.000 title abstract 2
- 229960001592 paclitaxel Drugs 0.000 title abstract 2
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 title abstract 2
- 238000002560 therapeutic procedure Methods 0.000 title abstract 2
- 230000002411 adverse Effects 0.000 title 1
- 230000000694 effects Effects 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 abstract 1
- 201000010000 Agranulocytosis Diseases 0.000 abstract 1
- 101150109801 CYP2C8 gene Proteins 0.000 abstract 1
- 206010071602 Genetic polymorphism Diseases 0.000 abstract 1
- 206010018687 Granulocytopenia Diseases 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/172—Haplotypes
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Biomedical Technology (AREA)
- Plant Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003375369 | 2003-11-05 | ||
| PCT/JP2004/016805 WO2005045029A1 (ja) | 2003-11-05 | 2004-11-05 | パクリタキセル療法による副作用を予測する方法およびキット |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE440153T1 true ATE440153T1 (de) | 2009-09-15 |
Family
ID=34567070
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04799655T ATE440153T1 (de) | 2003-11-05 | 2004-11-05 | Verfahren und kit zur abschätzung der nebenwirkung durch eine paclitaxel-therapie |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20070238098A1 (de) |
| EP (1) | EP1688492B1 (de) |
| JP (1) | JP4549297B2 (de) |
| KR (1) | KR20070003777A (de) |
| CN (1) | CN1871349B (de) |
| AT (1) | ATE440153T1 (de) |
| DE (1) | DE602004022702D1 (de) |
| WO (1) | WO2005045029A1 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7468248B2 (en) | 2002-12-31 | 2008-12-23 | Cargill, Incorporated | Methods and systems for inferring bovine traits |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6528260B1 (en) * | 1999-03-25 | 2003-03-04 | Genset, S.A. | Biallelic markers related to genes involved in drug metabolism |
| US6136846A (en) * | 1999-10-25 | 2000-10-24 | Supergen, Inc. | Formulation for paclitaxel |
| AU2002344369A1 (en) * | 2001-06-01 | 2002-12-16 | Epidauros Biotechnologie Ag | Polymorphisms in the human gene for cytochrome p450 polypeptide 2c8 and their use in diagnostic and therapeutic applications |
| JP2003093068A (ja) * | 2001-09-25 | 2003-04-02 | Kokuritsu Iyakuhin Shokuhin Eisei Kenkyusho | 代謝酵素cyp2c8の多型を利用した、薬物代謝の検査方法および検査薬並びに薬物代謝を改善する化合物のスクリーニング方法 |
| WO2003045227A2 (en) * | 2001-11-28 | 2003-06-05 | Dnaprint Genomics, Inc. | Single nucleotide polymorphisms and combinations thereof predictive for paclitaxel responsiveness |
-
2004
- 2004-11-05 DE DE602004022702T patent/DE602004022702D1/de not_active Expired - Lifetime
- 2004-11-05 AT AT04799655T patent/ATE440153T1/de not_active IP Right Cessation
- 2004-11-05 US US10/578,077 patent/US20070238098A1/en not_active Abandoned
- 2004-11-05 WO PCT/JP2004/016805 patent/WO2005045029A1/ja not_active Ceased
- 2004-11-05 CN CN2004800313890A patent/CN1871349B/zh not_active Expired - Fee Related
- 2004-11-05 KR KR1020067010911A patent/KR20070003777A/ko not_active Withdrawn
- 2004-11-05 EP EP04799655A patent/EP1688492B1/de not_active Expired - Lifetime
- 2004-11-05 JP JP2005515376A patent/JP4549297B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1688492B1 (de) | 2009-08-19 |
| DE602004022702D1 (de) | 2009-10-01 |
| KR20070003777A (ko) | 2007-01-05 |
| JP4549297B2 (ja) | 2010-09-22 |
| CN1871349B (zh) | 2011-04-06 |
| CN1871349A (zh) | 2006-11-29 |
| US20070238098A1 (en) | 2007-10-11 |
| EP1688492A1 (de) | 2006-08-09 |
| JPWO2005045029A1 (ja) | 2007-05-17 |
| WO2005045029A1 (ja) | 2005-05-19 |
| EP1688492A4 (de) | 2006-12-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |