ATE440819T1 - Substanz mit oxidationshemmender, geroprotektiver und antiischämischer wirkung und verfahren zu deren herstellung - Google Patents

Substanz mit oxidationshemmender, geroprotektiver und antiischämischer wirkung und verfahren zu deren herstellung

Info

Publication number
ATE440819T1
ATE440819T1 AT05807224T AT05807224T ATE440819T1 AT E440819 T1 ATE440819 T1 AT E440819T1 AT 05807224 T AT05807224 T AT 05807224T AT 05807224 T AT05807224 T AT 05807224T AT E440819 T1 ATE440819 T1 AT E440819T1
Authority
AT
Austria
Prior art keywords
geroprotective
antischemic
inhibiting
oxidation
substance
Prior art date
Application number
AT05807224T
Other languages
English (en)
Inventor
Leonid Dmitrievich Smipnov
Michail Arkadievich Ostrovsky
Aleksey Michailovich Sipyagin
Aleksandr Doncov
Original Assignee
Marvel Lifesciences Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Marvel Lifesciences Ltd filed Critical Marvel Lifesciences Ltd
Application granted granted Critical
Publication of ATE440819T1 publication Critical patent/ATE440819T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Anti-Oxidant Or Stabilizer Compositions (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT05807224T 2004-05-12 2005-07-11 Substanz mit oxidationshemmender, geroprotektiver und antiischämischer wirkung und verfahren zu deren herstellung ATE440819T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU2004114314/04A RU2276138C2 (ru) 2004-05-12 2004-05-12 Вещество, обладающее антиоксидантной, геропротекторной и противоишемической активностью, и способ его получения
PCT/IB2005/003636 WO2007017713A1 (fr) 2004-05-12 2005-07-11 Substance possedant un effet antioxydant, geroprotecteur et anti-ischemique et procede de fabrication correspondant

Publications (1)

Publication Number Publication Date
ATE440819T1 true ATE440819T1 (de) 2009-09-15

Family

ID=36021747

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05807224T ATE440819T1 (de) 2004-05-12 2005-07-11 Substanz mit oxidationshemmender, geroprotektiver und antiischämischer wirkung und verfahren zu deren herstellung

Country Status (11)

Country Link
US (1) US8044210B2 (de)
EP (1) EP1911746B1 (de)
JP (1) JP2009501712A (de)
CN (1) CN101233110B (de)
AT (1) ATE440819T1 (de)
BR (1) BRPI0520433A2 (de)
CA (1) CA2614857A1 (de)
DE (1) DE602005016317D1 (de)
PL (1) PL1911746T3 (de)
RU (1) RU2276138C2 (de)
WO (1) WO2007017713A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2276138C2 (ru) 2004-05-12 2006-05-10 Марвел Лайф Сайнсез Лтд. Вещество, обладающее антиоксидантной, геропротекторной и противоишемической активностью, и способ его получения
RU2326665C1 (ru) * 2007-04-03 2008-06-20 Марвел ЛайфСайнсез Лимитед, Великобритания Средство, обладающее противогипоксическим, противоинсультным, улучшающим память действием
EA011238B1 (ru) * 2007-04-03 2009-02-27 Марвел Лайфсайнсез Лтд. Средство, обладающее противогипоксическим, противоинсультным, улучшающим память действием
CN101903352B (zh) * 2007-12-18 2013-07-10 德米特里·瓦莱利维奇·比留科夫 取代的3-羟基吡啶系化合物及其药物组合物
EP2265252A2 (de) * 2008-02-19 2010-12-29 Marvel Lifesciences Limited Sterile ophthalmische zubereitungen und herstellungsverfahren dafür
WO2009116078A2 (en) * 2008-02-19 2009-09-24 M. J. Biopharm Pvt. Ltd. Oral dosage formulations and process of preparation thereof
EP2252265A4 (de) * 2008-02-19 2011-04-20 Marvel Lifesciences Ltd Injizierbare zubereitungen und herstellungsverfahren dafür
EA020371B1 (ru) 2012-07-19 2014-10-30 Хэндельсорт Аг Алкилзамещенные 3-гидроксипиридины для лечения депрессии
RU2671200C2 (ru) * 2015-12-07 2018-10-30 Закрытое Акционерное Общество "Фармфирма "Сотекс" Способ получения 6-метил-2-этилпиридин-3-ол соли (2S)-2-ацетаминопентандиовой кислоты

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2847926B2 (ja) * 1990-08-01 1999-01-20 トヨタ自動車株式会社 自動変速機の変速制御装置
JPH0496277A (ja) * 1990-08-06 1992-03-27 Fujitsu Ltd 不揮発性半導体記憶装置
IT1247528B (it) * 1991-04-24 1994-12-17 Medea Res Srl Composto ad attivita' terapeutica,sua preparazione e composizioni farmaceutiche che lo contengono
RU2070010C1 (ru) * 1993-08-31 1996-12-10 Эдуард Сергеевич Аветисов Средство антиоксидантной защиты сред и тканей глаза
RU2112512C1 (ru) 1995-09-22 1998-06-10 Иванов Евгений Васильевич Биологичеcки активная пищевая добавка "глутапирон", обладающая антиканцерогенным и геропротекторным действием
RU2153872C2 (ru) * 1997-10-15 2000-08-10 Амбалов Юрий Михайлович Способ лечения дифтерии
RU2197199C2 (ru) * 2000-05-12 2003-01-27 Государственное учреждение Межотраслевой научно-технический комплекс "Микрохирургия глаза" Способ лечения амблиопии
JP2002017295A (ja) * 2000-07-05 2002-01-22 Yamagami Suehito 眼疾患改善作用及び眼の機能維持作用を有する健康補助食品
RU2210568C1 (ru) * 2001-12-14 2003-08-20 Промоненков Виктор Кириллович Способ получения производных 2-этил-6-метил-3-гидроксипиридина
RU2250210C1 (ru) * 2003-07-25 2005-04-20 Институт Проблем Химической Физики Российской Академии Наук (Ипхф Ран) Нитроксисукцинат 2,4,6-триметил-3-оксипиридина и способ его получения
RU2276138C2 (ru) 2004-05-12 2006-05-10 Марвел Лайф Сайнсез Лтд. Вещество, обладающее антиоксидантной, геропротекторной и противоишемической активностью, и способ его получения

Also Published As

Publication number Publication date
RU2276138C2 (ru) 2006-05-10
PL1911746T3 (pl) 2010-07-30
EP1911746B1 (de) 2009-08-26
US20090198068A1 (en) 2009-08-06
WO2007017713A1 (fr) 2007-02-15
CN101233110A (zh) 2008-07-30
DE602005016317D1 (de) 2009-10-08
CN101233110B (zh) 2011-09-14
JP2009501712A (ja) 2009-01-22
US8044210B2 (en) 2011-10-25
BRPI0520433A2 (pt) 2009-05-12
CA2614857A1 (en) 2007-02-15
EP1911746A1 (de) 2008-04-16

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