ATE442364T1 - Kristalline form von linezolid - Google Patents
Kristalline form von linezolidInfo
- Publication number
- ATE442364T1 ATE442364T1 AT03769887T AT03769887T ATE442364T1 AT E442364 T1 ATE442364 T1 AT E442364T1 AT 03769887 T AT03769887 T AT 03769887T AT 03769887 T AT03769887 T AT 03769887T AT E442364 T1 ATE442364 T1 AT E442364T1
- Authority
- AT
- Austria
- Prior art keywords
- crystalline form
- linezolide
- linezolid
- preparation
- relates
- Prior art date
Links
- TYZROVQLWOKYKF-ZDUSSCGKSA-N linezolid Chemical compound O=C1O[C@@H](CNC(=O)C)CN1C(C=C1F)=CC=C1N1CCOCC1 TYZROVQLWOKYKF-ZDUSSCGKSA-N 0.000 title abstract 2
- 229960003907 linezolid Drugs 0.000 title abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Photoreceptors In Electrophotography (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IN2003/000336 WO2005035530A1 (en) | 2003-10-16 | 2003-10-16 | A novel crystalline form of linezolid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE442364T1 true ATE442364T1 (de) | 2009-09-15 |
Family
ID=34430675
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03769887T ATE442364T1 (de) | 2003-10-16 | 2003-10-16 | Kristalline form von linezolid |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US7714128B2 (de) |
| EP (3) | EP2100884A1 (de) |
| AT (1) | ATE442364T1 (de) |
| AU (1) | AU2003278592A1 (de) |
| DE (2) | DE60329237D1 (de) |
| DK (1) | DK1673370T3 (de) |
| ES (3) | ES2331001T3 (de) |
| HU (1) | HUE051230T2 (de) |
| PT (1) | PT1673370E (de) |
| WO (1) | WO2005035530A1 (de) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1673370E (pt) | 2003-10-16 | 2009-11-05 | Symed Labs Ltd | Forma cristalina de linezolida |
| WO2005099353A2 (en) | 2004-04-19 | 2005-10-27 | Symed Labs Limited | A novel process for the preparation of linezolid and related compounds |
| CA2572207A1 (en) * | 2004-06-29 | 2006-10-19 | Teva Pharmaceutical Industries Ltd. | Solid forms of linezolid and processes for preparation thereof |
| EP2174935A1 (de) * | 2004-06-29 | 2010-04-14 | Teva Pharmaceutical Industries Ltd | Linezolidzusammensetzungen |
| EP1866295A2 (de) | 2005-02-24 | 2007-12-19 | Teva Pharmaceutical Industries Ltd | Verfahren zur herstellung von linezolidzwischenprodukten |
| DK1749517T3 (da) * | 2005-07-20 | 2008-11-03 | Teva Pharma | Stabil farmaceutiske sammensætning af linezolid form IV |
| EP2033960A3 (de) | 2007-09-04 | 2009-04-29 | Dipharma Francis S.r.l. | Kristalline Linezolidhydratform und Linezolidsalze |
| IT1390957B1 (it) * | 2008-07-07 | 2011-10-27 | Dipharma Francis Srl | Sali di linezolid e loro uso nella preparazione di forme cristalline di linezolid |
| US20090093631A1 (en) * | 2007-09-06 | 2009-04-09 | Ben-Zion Dolitzky | Processes for the preparation of a linezolid intermediate, linezolid hydroxide |
| WO2009140466A2 (en) * | 2008-05-14 | 2009-11-19 | Dr. Reddy's Laboratories Ltd. | Linezolid co-crystals |
| EP2493867A1 (de) | 2009-10-28 | 2012-09-05 | Synthon BV | Verfahren zur herstellung einer kristallinen form von linezolid |
| WO2011050826A1 (en) * | 2009-10-28 | 2011-05-05 | Synthon B.V. | Process for making crystalline form a of linezolid |
| US20130137864A1 (en) | 2009-12-26 | 2013-05-30 | Jayaraman Venkat Raman | Process for the preparation of linezolid |
| EP2603505A1 (de) | 2010-08-11 | 2013-06-19 | Synthon BV | Verfahren zur herstellung von linezolid |
| EP2690100A1 (de) | 2010-08-11 | 2014-01-29 | Synhton B.V. | Verfahren zur Linezpolid Herstellung |
| WO2012029074A2 (en) | 2010-09-02 | 2012-03-08 | Hetero Research Foundation | Pharmaceutical compositions of linezolid |
| CN102070548B (zh) * | 2011-01-13 | 2012-12-26 | 浙江新东港药业股份有限公司 | 一种晶型ⅰ型利奈唑胺的蒸发结晶工艺 |
| US20140114065A1 (en) | 2011-02-24 | 2014-04-24 | Lee Phama Limited | Anhydrous linezolid crystalline form-ii |
| EP2683696A1 (de) | 2011-03-09 | 2014-01-15 | Synthon BV | Verfahren zur herstellung einer kristallinen form von linezolid |
| CN105461648B (zh) * | 2011-05-03 | 2018-01-12 | 江苏豪森药业集团有限公司 | 利奈唑胺的晶型及其制备方法 |
| ITMI20111311A1 (it) * | 2011-07-14 | 2013-01-15 | Dipharma Francis Srl | Sali di linezolid e loro uso nella preparazione di forme cristalline di linezolid |
| WO2013072923A1 (en) | 2011-09-19 | 2013-05-23 | Cadila Healthcare Limited | Process for the preparation of crystalline linezolid |
| WO2013093751A1 (en) * | 2011-12-24 | 2013-06-27 | Alembic Pharmaceuticals Limited | Packaging for linezolid |
| WO2013111048A1 (en) | 2012-01-24 | 2013-08-01 | Jubilant Life Sciences Limited | Improved process for the preparation of stable crystalline form-i of linezolid, substantially free of residual solvent |
| WO2013120496A1 (en) | 2012-02-14 | 2013-08-22 | Pharmathen S.A. | Process for the preparation of linezolid in crystalline form and salts thereof |
| WO2013190559A1 (en) * | 2012-06-19 | 2013-12-27 | Symed Labs Limited | Improved processes for the preparation of linezolid crystalline form iii |
| US9492459B2 (en) | 2012-08-10 | 2016-11-15 | Indoco Remedies Limited | Pharmaceutical composition of linezolid |
| WO2014071990A1 (en) | 2012-11-09 | 2014-05-15 | Synthon Bv | Process for making linezolid |
| WO2014118809A1 (en) | 2013-01-29 | 2014-08-07 | Actavis Group Ptc Ehf. | Pharmaceutical composition with linezolid |
| WO2015068121A1 (en) | 2013-11-06 | 2015-05-14 | Unimark Remedies Ltd. | Process for preparation of crystalline form i of linezolid and its compositions |
| CN105254580B (zh) * | 2014-04-22 | 2018-01-02 | 江苏豪森药业集团有限公司 | 利奈唑胺晶型的制备方法 |
| WO2016113751A1 (en) * | 2015-01-13 | 2016-07-21 | Nosch Labs Private Limited | Process for preparing crystalline linezolid form-iii |
| WO2018051360A1 (en) * | 2016-09-16 | 2018-03-22 | Lee Pharma Limited | A novel process for the preparation of crystalline linezolid form-iii |
| JP7101694B2 (ja) | 2016-11-16 | 2022-07-15 | ペルシカ ファーマシューティカルズ リミテッド | 腰痛のための抗生物質製剤 |
| EP3709970B1 (de) | 2017-11-16 | 2025-05-14 | Persica Pharmaceuticals Ltd. | Linezolidformulierungen |
| CN110194750A (zh) * | 2019-06-19 | 2019-09-03 | 四川美大康华康药业有限公司 | 一种利奈唑胺的制备方法及精制方法 |
| EP4415722A1 (de) | 2021-10-12 | 2024-08-21 | Persica Pharmaceuticals Ltd. | Behandlung von rückenschmerzen |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US583870A (en) * | 1897-06-01 | Wrench | ||
| DE2810349A1 (de) | 1978-03-10 | 1979-09-20 | Kali Chemie Pharma Gmbh | Verfahren zur herstellung von 3-hydroxy-6-phenyl-1,2,3,4-tetrahydro- 1,5-benzodiazocinen |
| FR2506769A2 (fr) | 1978-06-09 | 1982-12-03 | Delalande Sa | Para-((cyano-5 n pentyl-1) phenyl)-3 methoxymethyl-5 oxazolidinone-2, son procede de preparation et ses applications en therapeutique |
| US4340606A (en) | 1980-10-23 | 1982-07-20 | E. I. Du Pont De Nemours And Company | 3-(p-Alkylsulfonylphenyl)oxazolidinone derivatives as antibacterial agents |
| FR2608604B1 (fr) | 1986-12-19 | 1989-04-28 | Delalande Sa | Derives 5-hydroxyethyles de l'oxazolidinone-2, leurs procedes de preparation et leurs applications en therapeutique |
| US5006528A (en) | 1988-10-31 | 1991-04-09 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives |
| DE9310451U1 (de) | 1993-03-05 | 1994-06-30 | Landis & Gyr Business Support Ag, Zug | Steuer- bzw. Regeleinrichtung für Gas-Feuerungsautomaten von Heizungsanlagen |
| DE59306401D1 (de) | 1993-03-11 | 1997-06-12 | Landis & Gyr Tech Innovat | Brennerregler |
| US5688792A (en) * | 1994-08-16 | 1997-11-18 | Pharmacia & Upjohn Company | Substituted oxazine and thiazine oxazolidinone antimicrobials |
| MY115155A (en) | 1993-09-09 | 2003-04-30 | Upjohn Co | Substituted oxazine and thiazine oxazolidinone antimicrobials. |
| ES2166073T3 (es) * | 1996-04-11 | 2002-04-01 | Upjohn Co | Procedimiento para preparar oxazolidinonas. |
| EP0890791A1 (de) | 1997-07-11 | 1999-01-13 | Electrowatt Technology Innovation AG | Steuer- und Regelgerät für einen Brenner |
| DK1028940T3 (da) | 1997-11-07 | 2007-07-30 | Pharmacia & Upjohn Co Llc | Fremgangsmåde til fremstilling af oxazolidinoner |
| US6444813B2 (en) | 2000-02-02 | 2002-09-03 | Pharmacia & Upjohn Company | Linezolid-crystal form II |
| AR027261A1 (es) * | 2000-02-02 | 2003-03-19 | Upjohn Co | Linezolid forma cristalina ii |
| MY127336A (en) | 2000-03-22 | 2006-11-30 | Upjohn Co | Container for linezolid iv solution |
| DE10037585A1 (de) * | 2000-08-02 | 2002-02-14 | Valeo Schalter & Sensoren Gmbh | Rückstellvorrichtung für einen Blinkerschalter in Kraftfahrzeugen |
| KR100818875B1 (ko) | 2000-08-14 | 2008-04-01 | 테바 파마슈티컬 인더스트리즈 리미티드 | 리스페리돈의 제조 |
| WO2002072066A1 (en) * | 2001-02-05 | 2002-09-19 | Pharmacia & Upjohn Company | Composition for rectal delivery of an oxazolidinone antibacterial drug |
| JP2005504007A (ja) * | 2001-04-20 | 2005-02-10 | ファルマシア アンド アップジョン カンパニー リミティド ライアビリティー カンパニー | オキサゾリジノンの製法 |
| CN1155585C (zh) | 2001-12-19 | 2004-06-30 | 中国医学科学院医药生物技术研究所 | 3,5-取代噁唑烷酮衍生物及其制备方法和应用 |
| US6992219B2 (en) | 2002-08-09 | 2006-01-31 | Cephalon France | Modafinil polymorphic forms |
| PT1673370E (pt) | 2003-10-16 | 2009-11-05 | Symed Labs Ltd | Forma cristalina de linezolida |
| WO2005099353A2 (en) | 2004-04-19 | 2005-10-27 | Symed Labs Limited | A novel process for the preparation of linezolid and related compounds |
| EP2174935A1 (de) | 2004-06-29 | 2010-04-14 | Teva Pharmaceutical Industries Ltd | Linezolidzusammensetzungen |
| EP1768967B1 (de) | 2004-07-20 | 2009-04-22 | Symed Labs Limited | Neue zwischenprodukte für linezolid und verwandte verbindungen |
-
2003
- 2003-10-16 PT PT03769887T patent/PT1673370E/pt unknown
- 2003-10-16 EP EP20090163348 patent/EP2100884A1/de not_active Withdrawn
- 2003-10-16 EP EP03769887A patent/EP1673370B1/de not_active Revoked
- 2003-10-16 DE DE60329237T patent/DE60329237D1/de not_active Expired - Lifetime
- 2003-10-16 ES ES03769887T patent/ES2331001T3/es not_active Expired - Lifetime
- 2003-10-16 ES ES15155714T patent/ES2803516T3/es not_active Expired - Lifetime
- 2003-10-16 AU AU2003278592A patent/AU2003278592A1/en not_active Abandoned
- 2003-10-16 WO PCT/IN2003/000336 patent/WO2005035530A1/en not_active Ceased
- 2003-10-16 HU HUE15155714A patent/HUE051230T2/hu unknown
- 2003-10-16 AT AT03769887T patent/ATE442364T1/de active
- 2003-10-16 DK DK03769887T patent/DK1673370T3/da active
- 2003-10-16 US US10/524,478 patent/US7714128B2/en not_active Expired - Lifetime
- 2003-10-16 DE DE2009163348 patent/DE09163348T1/de active Pending
- 2003-10-16 EP EP15155714.7A patent/EP2902386B1/de not_active Expired - Lifetime
- 2003-10-16 ES ES09163348T patent/ES2331454T1/es active Pending
-
2007
- 2007-09-26 US US11/861,406 patent/US7732597B2/en not_active Expired - Fee Related
- 2007-09-26 US US11/861,433 patent/US7718800B2/en not_active Expired - Fee Related
- 2007-09-26 US US11/861,340 patent/US7718799B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP2902386A1 (de) | 2015-08-05 |
| HUE051230T2 (hu) | 2021-03-01 |
| US20060128703A1 (en) | 2006-06-15 |
| US20080091011A1 (en) | 2008-04-17 |
| US7718799B2 (en) | 2010-05-18 |
| EP2100884A1 (de) | 2009-09-16 |
| DE09163348T1 (de) | 2010-01-07 |
| DE60329237D1 (de) | 2009-10-22 |
| WO2005035530A1 (en) | 2005-04-21 |
| US7718800B2 (en) | 2010-05-18 |
| US7714128B2 (en) | 2010-05-11 |
| AU2003278592A1 (en) | 2005-04-27 |
| ES2331001T3 (es) | 2009-12-18 |
| US20080090824A1 (en) | 2008-04-17 |
| DK1673370T3 (da) | 2009-12-07 |
| US7732597B2 (en) | 2010-06-08 |
| EP1673370B1 (de) | 2009-09-09 |
| ES2803516T3 (es) | 2021-01-27 |
| PT1673370E (pt) | 2009-11-05 |
| ES2331454T1 (es) | 2010-01-05 |
| US20080090820A1 (en) | 2008-04-17 |
| EP1673370A1 (de) | 2006-06-28 |
| EP2902386B1 (de) | 2020-04-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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