ATE443130T1 - Methode oder apparat zur kultivierung von zellen oder gewebe - Google Patents

Methode oder apparat zur kultivierung von zellen oder gewebe

Info

Publication number
ATE443130T1
ATE443130T1 AT01908154T AT01908154T ATE443130T1 AT E443130 T1 ATE443130 T1 AT E443130T1 AT 01908154 T AT01908154 T AT 01908154T AT 01908154 T AT01908154 T AT 01908154T AT E443130 T1 ATE443130 T1 AT E443130T1
Authority
AT
Austria
Prior art keywords
cell
tissue
culture
cultivating
environment
Prior art date
Application number
AT01908154T
Other languages
English (en)
Inventor
Takao Takagi
Setsuo Watanabe
Hidetada Takai
Ibuki Kinouchi
Shuichi Mizuno
Julie Glowacki
Original Assignee
Takagi Kogyo Kk
Brigham & Womens Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takagi Kogyo Kk, Brigham & Womens Hospital filed Critical Takagi Kogyo Kk
Application granted granted Critical
Publication of ATE443130T1 publication Critical patent/ATE443130T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M3/00—Tissue, human, animal or plant cell, or virus culture apparatus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/14—Bags
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/14—Pressurized fluid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/04—Mechanical means, e.g. sonic waves, stretching forces, pressure or shear stimuli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/40—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pressure
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Cell Biology (AREA)
  • Mechanical Engineering (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Clinical Laboratory Science (AREA)
  • Virology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT01908154T 2000-03-02 2001-02-28 Methode oder apparat zur kultivierung von zellen oder gewebe ATE443130T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000057585A JP3865354B2 (ja) 2000-03-02 2000-03-02 細胞又は組織の培養方法
PCT/JP2001/001516 WO2001064848A1 (en) 2000-03-02 2001-02-28 Method and apparatus for culturing cell or tissue

Publications (1)

Publication Number Publication Date
ATE443130T1 true ATE443130T1 (de) 2009-10-15

Family

ID=18578342

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01908154T ATE443130T1 (de) 2000-03-02 2001-02-28 Methode oder apparat zur kultivierung von zellen oder gewebe

Country Status (10)

Country Link
US (3) US6432713B2 (de)
EP (1) EP1266960B1 (de)
JP (1) JP3865354B2 (de)
KR (1) KR100674788B1 (de)
CN (3) CN1737106B (de)
AT (1) ATE443130T1 (de)
AU (2) AU2001236002B2 (de)
CA (1) CA2401559C (de)
DE (1) DE60139926D1 (de)
WO (1) WO2001064848A1 (de)

Families Citing this family (76)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2441994C (en) 2001-03-23 2012-08-14 Laurence J. Berlowitz Tarrant Composition and methods for the production of biological tissues and tissue constructs
US20040151705A1 (en) * 2002-03-22 2004-08-05 Shuichi Mizuno Neo-cartilage constructs and a method for preparation thereof
JP3896386B2 (ja) * 2001-10-22 2007-03-22 株式会社治研 インキュベータ
US20030098069A1 (en) * 2001-11-26 2003-05-29 Sund Wesley E. High purity fluid delivery system
JP4451582B2 (ja) * 2001-12-21 2010-04-14 高木産業株式会社 細胞・組織培養装置
JP4378909B2 (ja) * 2002-02-20 2009-12-09 株式会社日立プラントテクノロジー 生体細胞の培養制御方法及び培養装置の制御装置並びに培養装置
WO2003074100A1 (en) * 2002-03-04 2003-09-12 New X-National Technology K.K. Closed cell culture system
JP4067419B2 (ja) * 2002-03-04 2008-03-26 株式会社ネクスト21 閉鎖型細胞培養システム
US7468192B2 (en) * 2002-03-22 2008-12-23 Histogenics Corporation Method for repair of cartilage lesions
US7537780B2 (en) * 2002-03-22 2009-05-26 Histogenics Corporation Method for preparing and implanting a cartilage construct to treat cartilage lesions
US8492140B2 (en) * 2002-04-08 2013-07-23 Octane Biotech Inc. Automated tissue engineering system
US7744597B2 (en) 2002-06-26 2010-06-29 Lifenet Health Device and process for producing fiber products and fiber products produced thereby
JP3774466B2 (ja) * 2002-06-28 2006-05-17 株式会社生物有機化学研究所 キトサンと酸性生体高分子とのハイブリッド繊維および動物細胞培養基材
JP4666335B2 (ja) 2002-09-04 2011-04-06 晶夫 岸田 機械的振動による生物機能の制御方法とその装置
JP4086183B2 (ja) * 2002-09-24 2008-05-14 賢治 柏木 生体細胞又は組織の加重培養方法および装置
JP2004305148A (ja) * 2003-04-09 2004-11-04 Olympus Corp 自動培養装置
EP1612262A4 (de) * 2003-04-09 2009-07-22 Olympus Corp Vorrichtung zur behandlung von kulturen und automatische vorrichtung zur behandlung von kulturen
US7494811B2 (en) 2003-05-01 2009-02-24 Lifenet Health In vitro growth of tissues suitable to the formation of bone and bone forming tissue formed thereby
JP4607432B2 (ja) * 2003-05-12 2011-01-05 高木産業株式会社 細胞又は組織の培養装置
EP1780266A4 (de) * 2004-06-17 2009-09-09 Ken Nakata Zellkultivierungsverfahren mit biomechanischem belastungsreiz sowie dessen vorrichtung
WO2006022671A1 (en) * 2004-07-30 2006-03-02 Histogenics Corporation Method for in situ repair of injured, damaged, diseased or aged articular cartilage using neo-cartilage constructs and a method for preparation thereof
CN101035890B (zh) * 2004-07-30 2012-10-10 布赖汉姆妇女医院有限公司 经物理/物理化学刺激处理的无定形细胞递送载体
JP2006325556A (ja) * 2005-05-30 2006-12-07 Takagi Ind Co Ltd 加圧装置、培養装置及び加圧容器
HRP20090382T1 (hr) * 2005-06-17 2009-09-30 Merz Pharma Gmbh & Co.Kgaa Uređaj i postupak za proizvodnju biološko aktivnih spojeva fermentacijom
CA2623106C (en) 2005-09-19 2013-12-24 Histogenics Corporation Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof
JP5433129B2 (ja) 2006-07-10 2014-03-05 パーパス株式会社 細胞又は組織の培養方法
JP4981374B2 (ja) 2006-07-10 2012-07-18 パーパス株式会社 細胞又は組織の培養装置及び培養方法
DE102006032703A1 (de) * 2006-07-14 2008-01-24 OCé PRINTING SYSTEMS GMBH Verfahren und Anordnung zum Erzeugen einer vorgegebenen Umlaufgeschwindigkeit eines endlosen bandförmigen Bildträgers
JP5053628B2 (ja) * 2006-12-15 2012-10-17 パーパス株式会社 加圧装置、その加圧方法、ポンプ装置及び培養装置
JP5169035B2 (ja) * 2007-06-19 2013-03-27 株式会社Ihi 加圧試験方法及び装置
US8685107B2 (en) 2007-07-03 2014-04-01 Histogenics Corporation Double-structured tissue implant and a method for preparation and use thereof
US20090054984A1 (en) 2007-08-20 2009-02-26 Histogenics Corporation Method For Use Of A Double-Structured Tissue Implant For Treatment Of Tissue Defects
EP2182887B1 (de) 2007-08-20 2016-12-14 Histogenics Corporation Verfahren für verbesserte differenzierung mesenchymaler stammzellen anhand eines doppelstrukturierten gewebeimplantats
US9410113B2 (en) * 2007-10-26 2016-08-09 St3 Development Corporation Bioreactor system for three-dimensional tissue stimulator
JP5341540B2 (ja) * 2009-02-02 2013-11-13 敏昭 春山 きのこの液体種菌培養装置及びきのこの液体種菌の培養方法
DK2408401T3 (en) 2009-03-03 2016-07-18 Univ Columbia METHODS, DEVICES AND SYSTEMS FOR KNOGLEVÆGS- ENGINEERING FOR USING A bioreactor
DE102009028339A1 (de) 2009-08-07 2011-02-24 Wacker Chemie Ag Bioreaktor aus Siliconmaterialien
DE102009028338A1 (de) 2009-08-07 2011-02-10 Wacker Chemie Ag Bioreaktor mit Siliconbeschichtung
DE202010011059U1 (de) * 2009-08-13 2011-01-13 F. Hoffmann-La Roche Ag Stützeinheit zum Anbringen von mehreren Flüssigkeitsaufbewahrungseinheiten
CN101993823B (zh) * 2009-08-28 2012-11-07 中国航天员科研训练中心 环境自控型细胞学实验平台
JP5638216B2 (ja) 2009-10-09 2014-12-10 パーパス株式会社 加圧循環培養装置及び加圧循環培養システム
KR101126599B1 (ko) 2009-12-04 2012-03-23 한국과학기술원 세포 자극 장치
US20120034695A1 (en) * 2010-06-30 2012-02-09 Palaniappan Sethu Tissue/cell culturing system and related methods
CN101974416B (zh) * 2010-09-08 2013-07-31 牛刚 压强检测装置及微生物检验薄膜系统
JP5786444B2 (ja) * 2011-05-17 2015-09-30 東洋製罐グループホールディングス株式会社 細胞培養方法、及び細胞培養システム
KR20130044912A (ko) * 2011-10-25 2013-05-03 삼성전기주식회사 배양 장치 및 배양액 교체 방법
KR101441179B1 (ko) * 2012-03-05 2014-09-18 제주대학교 산학협력단 초음파 배양 접시 및 그것을 이용한 초음파 모니터링 시스템
JP6311609B2 (ja) * 2012-10-17 2018-04-18 コニカミノルタ株式会社 希少細胞の回収方法および検出方法
JP6249816B2 (ja) * 2013-03-28 2017-12-20 アークレイ株式会社 細胞培養装置、細胞培養システム、及び細胞培養方法
CN105316227A (zh) * 2014-07-28 2016-02-10 温州医科大学附属第二医院 一种多功能细胞模拟舱
US10640742B2 (en) * 2014-09-25 2020-05-05 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Hybrid linear actuator controlled hydraulic cell stretching
US10669525B2 (en) 2014-09-29 2020-06-02 Public University Corporation Yokohama City University Method for producing three-dimensional cell aggregates
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
CN104750022A (zh) * 2015-02-05 2015-07-01 西安交通大学 组织工程与3d打印肉组织生产加工系统及加工方法
US20180066223A1 (en) * 2015-04-17 2018-03-08 Xcell Biosciences, Inc. Cancer cell enrichment system
US20180100134A1 (en) * 2015-04-17 2018-04-12 Xcell Biosciences, Inc. Cancer cell enrichment system
CN108431199B (zh) * 2016-01-05 2022-04-08 日本板硝子株式会社 反应处理装置和反应处理方法
RU2626526C1 (ru) * 2016-04-19 2017-07-28 Федеральное государственное бюджетное учреждение "Национальный исследовательский центр "Курчатовский институт" Система создания биоинженерных моделей тканей животных и человека
IL301152A (en) * 2017-04-07 2023-05-01 Epibone Inc System and method for seeding and culturing
KR102546681B1 (ko) 2017-09-01 2023-06-22 론차 콜로그네 게엠베하 엔드-투-엔드 세포 요법의 자동화
CN108467834B (zh) * 2018-02-11 2023-07-25 温州医科大学 一种压力可控的小型细胞培养装置
KR102110252B1 (ko) * 2018-05-29 2020-05-14 한국과학기술연구원 가압환경 세포의 배양 장치 및 배양 방법
US20210198635A1 (en) * 2018-08-20 2021-07-01 I Peace, Inc. Cell culture or induction method
CA3113125A1 (en) 2018-09-28 2020-04-02 Octane Biotech Inc. Magnetic separation
JP7598864B2 (ja) 2018-12-21 2024-12-12 ロンザ ウォーカーズヴィル,インコーポレーテッド ウイルスベクターの自動産生方法
EP3898932A4 (de) 2018-12-21 2022-08-03 Octane Biotech Inc. Karussell für modulare biologische produktionseinheiten
KR102240707B1 (ko) * 2018-12-24 2021-04-16 연세대학교 산학협력단 약제 유효성을 결정하기 위한 어셈블리
TWI732357B (zh) * 2018-12-27 2021-07-01 財團法人工業技術研究院 細胞培養裝置及方法
SG11202108473XA (en) 2019-02-08 2021-09-29 Lonza Walkersville Inc Cell concentration methods and devices for use in automated bioreactors
FR3094012B1 (fr) * 2019-03-20 2022-08-12 Cherry Biotech Sas Procédé d'enrichissement en gaz et simultanément de déplacement d’un fluide et dispositif pour le contrôle de l'environnement cellulaire sur une plaque de culture cellulaire multipuits correspondant.
EP4048773A4 (de) 2019-10-24 2024-01-03 Octane Biotech Inc. Zellkulturkammer mit verbesserten zellkontaktflächen
JP2023501443A (ja) 2019-11-11 2023-01-18 ロンザ ウォーカーズヴィル,インコーポレーテッド 自動化された細胞処理のための品質制御方法
JP2021126051A (ja) * 2020-02-10 2021-09-02 株式会社東海ヒット 培養環境圧力自在変更装置及び当該装置を備えた灌流培養システム
CN113637579A (zh) * 2020-04-27 2021-11-12 复旦大学 一种静液压可调的细胞和组织加压培养装置
JP7666933B2 (ja) * 2021-01-13 2025-04-22 Ckd株式会社 細胞培養システム
CN114350591A (zh) * 2022-01-13 2022-04-15 中山大学附属第一医院 一种在压力条件下培养细胞的方法

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3172839D1 (en) * 1980-09-11 1985-12-12 Atomic Energy Authority Uk Improvements in or relating to composite materials
US5266476A (en) * 1985-06-18 1993-11-30 Yeda Research & Development Co., Ltd. Fibrous matrix for in vitro cell cultivation
US5026649A (en) * 1986-03-20 1991-06-25 Costar Corporation Apparatus for growing tissue cultures in vitro
EP0260627B1 (de) * 1986-09-19 1993-06-16 Shimadzu Corporation Druckbrutschrank
US5162225A (en) * 1989-03-17 1992-11-10 The Dow Chemical Company Growth of cells in hollow fibers in an agitated vessel
JP3095464B2 (ja) 1991-08-08 2000-10-03 宇宙開発事業団 細胞培養装置
IT1251381B (it) 1991-08-30 1995-05-09 Pirelli Dispositivo di comando per camere di vulcanizzazione in presse di vulcanizzazione, e procedimento di comando attuato da detto dispositivo.
US5330915A (en) 1991-10-18 1994-07-19 Endotronics, Inc. Pressure control system for a bioreactor
DE4206585C2 (de) * 1992-03-03 1994-11-24 Augustinus Dr Med Bader Vorrichtung zur Massenkultur von Zellen
JPH0754656B2 (ja) 1992-05-15 1995-06-07 帝国通信工業株式会社 押釦スイッチのキートップの製造方法
US5656492A (en) 1993-02-12 1997-08-12 Brigham And Women's Hospital, Inc. Cell induction device
DE4306661C2 (de) 1993-03-03 1995-04-20 Michael Dipl Biol Sittinger Verfahren zum Herstellen eines Implantates aus Zellkulturen
JPH06343457A (ja) 1993-06-10 1994-12-20 Power Fuiirudo:Kk 加圧培養方法および培養容器
US5686301A (en) 1993-09-02 1997-11-11 Heraeus Instruments Gmbh Culture vessel for cell cultures
JPH07184634A (ja) * 1993-12-28 1995-07-25 Ajinomoto Co Inc 微生物好気培養における培養方法及び装置
US5882918A (en) * 1995-08-08 1999-03-16 Genespan Corporation Cell culture incubator
JPH07298869A (ja) 1994-03-08 1995-11-14 Kanegafuchi Chem Ind Co Ltd 微生物の付着および沈澱を防止して培養する方法
US5792603A (en) * 1995-04-27 1998-08-11 Advanced Tissue Sciences, Inc. Apparatus and method for sterilizing, seeding, culturing, storing, shipping and testing tissue, synthetic or native, vascular grafts
JPH09313166A (ja) 1996-05-31 1997-12-09 Sanei Medical Support Kk 細胞培養装置
US6048723A (en) * 1997-12-02 2000-04-11 Flexcell International Corporation Flexible bottom culture plate for applying mechanical load to cell cultures
US6037141A (en) * 1998-06-04 2000-03-14 Banes; Albert J. Culture compression device
JP2961107B1 (ja) * 1998-07-21 1999-10-12 デベロップメント センター フォー バイオテクノロジー 空気動力圧力差式淹浸バイオリアクター

Also Published As

Publication number Publication date
US20010021529A1 (en) 2001-09-13
JP2001238663A (ja) 2001-09-04
CN1313601C (zh) 2007-05-02
CA2401559A1 (en) 2002-08-28
EP1266960A4 (de) 2004-07-14
EP1266960B1 (de) 2009-09-16
AU3600201A (en) 2001-09-12
US6599734B2 (en) 2003-07-29
CN1737106A (zh) 2006-02-22
WO2001064848A1 (en) 2001-09-07
AU2001236002B2 (en) 2006-02-16
CA2401559C (en) 2011-07-26
CN1737106B (zh) 2011-11-09
US20020098586A1 (en) 2002-07-25
DE60139926D1 (de) 2009-10-29
JP3865354B2 (ja) 2007-01-10
KR100674788B1 (ko) 2007-01-25
EP1266960A1 (de) 2002-12-18
CN100354406C (zh) 2007-12-12
US20020037586A1 (en) 2002-03-28
US6432713B2 (en) 2002-08-13
KR20030032925A (ko) 2003-04-26
CN1427888A (zh) 2003-07-02
WO2001064848A9 (en) 2001-11-22
US6607917B2 (en) 2003-08-19
CN1737107A (zh) 2006-02-22

Similar Documents

Publication Publication Date Title
DE60139926D1 (de) Methode oder apparat zur kultivierung von zellen oder gewebe
TR200200089T2 (tr) Kondrosit hücre transplantasyonu için metodlar; enstrümanlar ve maddeler
TW200517096A (en) Device and method for intradermal cell implantation
GB2386120A (en) Differentiated cells suitable for human therapy
MXPA02007137A (es) Fuente de tejido hepatico.
BR0210839A (pt) Sistema de recombinação, método para remover uma sequência de dna do dna cromossÈmico de uma célula ou organismo eucarióticos, organismo, cultura de célula, órgão, tecido, parte ou material de propagação transgênico, e, uso de um organismo ou de uma cultura de célula, órgão, tecido, parte ou material de propagação transgênico
DE60238058D1 (de) Verwendung von lysyloxydase inhibitoren zur zellkultur und gewebeaufbau
MY162929A (en) Apparatus and methods for controlling cellular development
WO2004096975A3 (en) Apparatus and methods for amplification of blood stem cell numbers
IL210618A (en) Cell cultures containing isolated and multiplied human cells other than embryonic and germ cells, pharmaceutical preparations containing them, methods of preparation, and methods for identifying modulators and differentiation factors.
ATE540001T1 (de) System und verfahren für nanoröhrchenwachstum über eine ionenimplantation mit einer katalytischen transmembrane
SI1625212T1 (sl) Umeten imunski organ
AU2003252396A8 (en) Apparatus for environment of cultivating/culturing plant, cultivation/culture method and cultivation/culture apparatus
EP1382670A4 (de) Zell- und strukturinkubator
DE69635924D1 (de) Isolierung und züchtung von schwannzellen
AU2001236002A1 (en) Method and apparatus for culturing cell or tissue
ATE544471T1 (de) Zusammensetzung mit iscom-teilchen und lebenden mikroorganismen
TW200636068A (en) A method of culturing a cell and use of the same
ATE356198T1 (de) Definierte systeme zur kultivieurng epithelialer zellen und anwendung derselben
DK1185621T3 (da) Overflade til cellekultur
DE69528473D1 (de) Verwendung von hepatozyten-wachstumsfaktor zur induzierung der proliferation und differenzierung von hämatopoietischen zellen
DE69837212D1 (de) Verfahren zur induzierung der osteoblastischen differenzierung der zellen des menschlichen extramedullären fettgewebes
ATE384121T1 (de) Verfahren zur kultivierung von menschlichen lungenmastzellen und deren anwendungen
GB2379446A (en) Cells,culture methods and their uses
WO2003072697A3 (de) Vorrichtung und verfahren zur kultivierung von gewebezellen

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties