ATE444753T1 - Gepufferte flüssige nikotinzusammensetzung zur pulmonalen verabreichung - Google Patents

Gepufferte flüssige nikotinzusammensetzung zur pulmonalen verabreichung

Info

Publication number
ATE444753T1
ATE444753T1 AT03756140T AT03756140T ATE444753T1 AT E444753 T1 ATE444753 T1 AT E444753T1 AT 03756140 T AT03756140 T AT 03756140T AT 03756140 T AT03756140 T AT 03756140T AT E444753 T1 ATE444753 T1 AT E444753T1
Authority
AT
Austria
Prior art keywords
pulmonary administration
liquid nicotine
buffered liquid
nicotine composition
composition
Prior art date
Application number
AT03756140T
Other languages
English (en)
Inventor
Mark Warchol
Folke Moren
Kristina Thyresson
Elisabeth Sthengel
Sven-Boerje Andersson
Original Assignee
Mcneil Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mcneil Ab filed Critical Mcneil Ab
Application granted granted Critical
Publication of ATE444753T1 publication Critical patent/ATE444753T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Addiction (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Otolaryngology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
AT03756140T 2002-06-03 2003-05-30 Gepufferte flüssige nikotinzusammensetzung zur pulmonalen verabreichung ATE444753T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0201669A SE0201669D0 (sv) 2002-06-03 2002-06-03 New formulation and use thereof
PCT/SE2003/000890 WO2003101454A1 (en) 2002-06-03 2003-05-30 A buffered, liquid nicotine composition for pulmonary administration

Publications (1)

Publication Number Publication Date
ATE444753T1 true ATE444753T1 (de) 2009-10-15

Family

ID=20288046

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03756140T ATE444753T1 (de) 2002-06-03 2003-05-30 Gepufferte flüssige nikotinzusammensetzung zur pulmonalen verabreichung

Country Status (19)

Country Link
EP (1) EP1509227B9 (de)
JP (2) JP4745658B2 (de)
CN (1) CN100500148C (de)
AR (1) AR039947A1 (de)
AT (1) ATE444753T1 (de)
AU (1) AU2003243074B2 (de)
BR (1) BR0311451A (de)
CA (1) CA2487699C (de)
DE (1) DE60329592D1 (de)
DK (1) DK1509227T3 (de)
ES (1) ES2332405T3 (de)
IL (1) IL165195A0 (de)
MX (1) MXPA04012041A (de)
NZ (1) NZ536863A (de)
RU (1) RU2283111C2 (de)
SE (1) SE0201669D0 (de)
TW (1) TW200407142A (de)
WO (1) WO2003101454A1 (de)
ZA (1) ZA200409793B (de)

Families Citing this family (102)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE521512C2 (sv) 2001-06-25 2003-11-11 Niconovum Ab Anordning för administrering av en substans till främre delen av en individs munhåla
PT1578422E (pt) 2002-12-20 2007-06-14 Niconovum Ab Material particulado contendo nicotina fisicamente e quimicamente estável
CN100381083C (zh) * 2003-04-29 2008-04-16 韩力 一种非可燃性电子喷雾香烟
CN2719043Y (zh) 2004-04-14 2005-08-24 韩力 雾化电子烟
LT2502911T (lt) 2004-06-24 2017-09-11 Vertex Pharmaceuticals Incorporated Atp surišančios kasetės transporterių moduliatoriai
US10244793B2 (en) 2005-07-19 2019-04-02 Juul Labs, Inc. Devices for vaporization of a substance
WO2007079139A2 (en) 2005-12-28 2007-07-12 Vertex Pharmaceuticals, Inc. Solid forms of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide
AU2007224584A1 (en) 2006-03-16 2007-09-20 Niconovum Ab Improved snuff composition
CN201067079Y (zh) 2006-05-16 2008-06-04 韩力 仿真气溶胶吸入器
WO2009038683A2 (en) * 2007-09-14 2009-03-26 Vertex Pharmaceuticals Incorporated Solid forms of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide
US12458635B2 (en) 2008-08-13 2025-11-04 Vertex Pharmaceuticals Incorporated Pharmaceutical composition and administrations thereof
US20100074949A1 (en) 2008-08-13 2010-03-25 William Rowe Pharmaceutical composition and administration thereof
AT507187B1 (de) 2008-10-23 2010-03-15 Helmut Dr Buchberger Inhalator
CN201379072Y (zh) 2009-02-11 2010-01-13 韩力 一种改进的雾化电子烟
SI2408750T1 (sl) 2009-03-20 2015-11-30 Vertex Pharmaceuticals Incorporated Postopek za izdelavo modulatorjev cistično-fibroznega transmembranskega regulatorja prevodnosti
IN2012DN02325A (de) * 2009-09-16 2015-08-21 Philip Morris Products Sa
CA2824970C (en) 2011-02-11 2016-05-03 Batmark Limited Inhaler component
AT510837B1 (de) 2011-07-27 2012-07-15 Helmut Dr Buchberger Inhalatorkomponente
US9399110B2 (en) 2011-03-09 2016-07-26 Chong Corporation Medicant delivery system
US8903228B2 (en) 2011-03-09 2014-12-02 Chong Corporation Vapor delivery devices and methods
MX356624B (es) 2011-03-09 2018-06-06 Chong Corp Sistema de entrega de medicamento.
EP3892125A3 (de) 2011-09-06 2022-01-05 Nicoventures Trading Limited Erwärmung eines rauchmaterials
PL2753202T3 (pl) 2011-09-06 2016-11-30 Podgrzewanie materiału przeznaczonego do palenia
AT511344B1 (de) 2011-10-21 2012-11-15 Helmut Dr Buchberger Inhalatorkomponente
US9907748B2 (en) * 2011-10-21 2018-03-06 Niconovum Usa, Inc. Excipients for nicotine-containing therapeutic compositions
EP2819670A1 (de) 2012-02-27 2015-01-07 Vertex Pharmaceuticals Incorporated Pharmazeutische zusammensetzung und verabreichung davon
GB201207039D0 (en) 2012-04-23 2012-06-06 British American Tobacco Co Heating smokeable material
GB2504075A (en) 2012-07-16 2014-01-22 Nicoventures Holdings Ltd Electronic smoking device
GB2504076A (en) 2012-07-16 2014-01-22 Nicoventures Holdings Ltd Electronic smoking device
GB201215273D0 (en) * 2012-08-28 2012-10-10 Kind Consumer Ltd Nicotine composition
GB201215282D0 (en) 2012-08-28 2012-10-10 Kind Consumer Ltd An inhaler
US10279934B2 (en) 2013-03-15 2019-05-07 Juul Labs, Inc. Fillable vaporizer cartridge and method of filling
GB2513637A (en) 2013-05-02 2014-11-05 Nicoventures Holdings Ltd Electronic cigarette
GB2513639A (en) 2013-05-02 2014-11-05 Nicoventures Holdings Ltd Electronic cigarette
KR102490695B1 (ko) * 2013-05-06 2023-01-19 쥴 랩스, 인크. 에어로졸 장치를 위한 니코틴 염 제제 및 그 방법
US11202470B2 (en) 2013-05-22 2021-12-21 Njoy, Inc. Compositions, devices, and methods for nicotine aerosol delivery
GB2514893B (en) 2013-06-04 2017-12-06 Nicoventures Holdings Ltd Container
US10251422B2 (en) 2013-07-22 2019-04-09 Altria Client Services Llc Electronic smoking article
US20160366947A1 (en) 2013-12-23 2016-12-22 James Monsees Vaporizer apparatus
US10159282B2 (en) 2013-12-23 2018-12-25 Juul Labs, Inc. Cartridge for use with a vaporizer device
US10058129B2 (en) 2013-12-23 2018-08-28 Juul Labs, Inc. Vaporization device systems and methods
USD842536S1 (en) 2016-07-28 2019-03-05 Juul Labs, Inc. Vaporizer cartridge
US10076139B2 (en) 2013-12-23 2018-09-18 Juul Labs, Inc. Vaporizer apparatus
KR102267997B1 (ko) 2013-12-23 2021-06-23 쥴 랩스, 인크. 기화 디바이스 시스템 및 방법
USD825102S1 (en) 2016-07-28 2018-08-07 Juul Labs, Inc. Vaporizer device with cartridge
US9839238B2 (en) 2014-02-28 2017-12-12 Rai Strategic Holdings, Inc. Control body for an electronic smoking article
GB201407426D0 (en) 2014-04-28 2014-06-11 Batmark Ltd Aerosol forming component
US10508096B2 (en) 2014-05-27 2019-12-17 R.J. Reynolds Tobacco Company Nicotine salts, co-crystals, and salt co-crystal complexes
EP3871515B1 (de) * 2014-05-27 2025-04-16 R. J. Reynolds Tobacco Company Nikotinsalze, co-kristalle und salz-co-kristallkomplexe
US9896429B2 (en) 2014-05-27 2018-02-20 R.J. Reynolds Tobacco Company Nicotine salts, co-crystals, and salt co-crystal complexes
GB2528673B (en) 2014-07-25 2020-07-01 Nicoventures Holdings Ltd Aerosol provision system
KR20170063954A (ko) 2014-10-07 2017-06-08 버텍스 파마슈티칼스 인코포레이티드 낭성 섬유증 막횡단 전도도 조절자의 조정제의 공-결정
GB2535427A (en) 2014-11-07 2016-08-24 Nicoventures Holdings Ltd Solution
GB2532062A (en) * 2014-11-07 2016-05-11 Nicoventures Holdings Ltd Container
KR102627987B1 (ko) 2014-12-05 2024-01-22 쥴 랩스, 인크. 교정된 투여량 제어
GB2533135B (en) 2014-12-11 2020-11-11 Nicoventures Holdings Ltd Aerosol provision systems
GB201505595D0 (en) 2015-03-31 2015-05-13 British American Tobacco Co Cartridge for use with apparatus for heating smokeable material
GB201505597D0 (en) 2015-03-31 2015-05-13 British American Tobacco Co Article for use with apparatus for heating smokable material
GB201511361D0 (en) 2015-06-29 2015-08-12 Nicoventures Holdings Ltd Electronic vapour provision system
GB201511349D0 (en) 2015-06-29 2015-08-12 Nicoventures Holdings Ltd Electronic aerosol provision systems
US20170055584A1 (en) 2015-08-31 2017-03-02 British American Tobacco (Investments) Limited Article for use with apparatus for heating smokable material
US11924930B2 (en) 2015-08-31 2024-03-05 Nicoventures Trading Limited Article for use with apparatus for heating smokable material
GB201516729D0 (en) * 2015-09-22 2015-11-04 The Technology Partnership Plc Liquid nicotine formulation
GB2542838B (en) 2015-10-01 2022-01-12 Nicoventures Trading Ltd Aerosol provision system
US20170119046A1 (en) 2015-10-30 2017-05-04 British American Tobacco (Investments) Limited Apparatus for Heating Smokable Material
EP4338735B1 (de) * 2015-11-25 2026-02-04 R. J. Reynolds Tobacco Company Nikotinsalze, cokristalle und cokristall-salzkomplexe
US9867397B2 (en) 2016-01-11 2018-01-16 Patrick Beymer Nicotine delivery system
MX377347B (es) 2016-02-11 2025-03-07 Juul Labs Inc Cartucho rellenable de vaporizador y metodo de relleno
WO2017139675A1 (en) 2016-02-11 2017-08-17 Pax Labs, Inc. Securely attaching cartridges for vaporizer devices
CA3015306A1 (en) * 2016-02-29 2017-09-08 Nicogen Ltd. Nicotine formulation and aerosols
US10405582B2 (en) 2016-03-10 2019-09-10 Pax Labs, Inc. Vaporization device with lip sensing
US11744964B2 (en) 2016-04-27 2023-09-05 Nicoventures Trading Limited Electronic aerosol provision system and vaporizer therefor
USD849996S1 (en) 2016-06-16 2019-05-28 Pax Labs, Inc. Vaporizer cartridge
USD848057S1 (en) 2016-06-23 2019-05-07 Pax Labs, Inc. Lid for a vaporizer
USD851830S1 (en) 2016-06-23 2019-06-18 Pax Labs, Inc. Combined vaporizer tamp and pick tool
USD836541S1 (en) 2016-06-23 2018-12-25 Pax Labs, Inc. Charging device
KR20200037220A (ko) * 2017-06-26 2020-04-08 누드 니코틴 인코포레이티드 니코틴 염 및 이의 제조 및 사용 방법
USD887632S1 (en) 2017-09-14 2020-06-16 Pax Labs, Inc. Vaporizer cartridge
GB2569940B (en) * 2017-11-01 2022-10-19 Nicoventures Trading Ltd Aerosolisable formulation
EP3574902A1 (de) * 2018-06-01 2019-12-04 Yatzz Limited Nikotinformulierung und modus der abgabe
GB201817864D0 (en) 2018-11-01 2018-12-19 Nicoventures Trading Ltd Aerosolisable formulation
GB201817860D0 (en) 2018-11-01 2018-12-19 Nicoventures Trading Ltd Aerosolised formulation
GB201817863D0 (en) * 2018-11-01 2018-12-19 Nicoventures Trading Ltd Aerosolisable formulation
GB201817867D0 (en) * 2018-11-01 2018-12-19 Nicoventures Trading Ltd Aerosolisable formulation
GB201817859D0 (en) * 2018-11-01 2018-12-19 Nicoventures Trading Ltd Aerosolisable formulation
BR112021024354A2 (pt) 2019-06-07 2022-01-11 Ncp Nextgen As Produto em bolsa oral e método para fabricar um produto em bolsa oral
WO2020254862A1 (en) 2019-06-20 2020-12-24 Shaheen Innovations Holding Limited Personal ultrasonic atomizer device
US12121056B2 (en) 2019-12-15 2024-10-22 Shaheen Innovations Holding Limited Hookah device
US12262738B2 (en) 2019-12-15 2025-04-01 Shaheen Innovations Holding Limited Ultrasonic mist inhaler
US11666713B2 (en) 2019-12-15 2023-06-06 Shaheen Innovations Holding Limited Mist inhaler devices
EP4031216B1 (de) 2019-12-15 2025-01-15 Shaheen Innovations Holding Limited Ultraschallnebelinhalator
US12201144B2 (en) 2019-12-15 2025-01-21 Shaheen Innovations Holding Limited Hookah device
US11730191B2 (en) 2019-12-15 2023-08-22 Shaheen Innovations Holding Limited Hookah device
US12538944B2 (en) 2019-12-15 2026-02-03 Shaheen Innovations Holding Limited Nicotine delivery device with identification arrangement
PL3837999T3 (pl) 2019-12-15 2022-10-10 Shaheen Innovations Holding Limited Inhalatory mgiełki
PL4292632T3 (pl) 2019-12-15 2025-11-24 Shaheen Innovations Holding Limited Ultradźwiękowy inhalator mgiełki
EP3860696B1 (de) 2019-12-15 2024-04-10 Shaheen Innovations Holding Limited Ultraschall-nebelinhalator
US11730193B2 (en) 2019-12-15 2023-08-22 Shaheen Innovations Holding Limited Hookah device
US11589610B2 (en) 2019-12-15 2023-02-28 Shaheen Innovations Holding Limited Nicotine delivery device having a mist generator device and a driver device
US12233207B2 (en) 2019-12-15 2025-02-25 Shaheen Innovations Holding Limited Mist inhaler devices
WO2021123867A1 (en) 2019-12-15 2021-06-24 Shaheen Innovations Holding Limited Ultrasonic mist inhaler
US20230188901A1 (en) 2021-12-15 2023-06-15 Shaheen Innovations Holding Limited Apparatus for transmitting ultrasonic waves

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2030862A (en) * 1978-04-10 1980-04-16 Smith A A composition for treating drug addiction such as smoking nicotine-containing products
DE3241437A1 (de) * 1982-11-10 1984-05-10 Ferdinand Prof. Dr.med. 6901 Wilhelmsfeld Schmidt Mittel zum zwecke der raucherentwoehnung und/oder fuer nebenwirkungsfreien nikotingenuss bei suchtrauchern
GB8301659D0 (en) * 1983-01-21 1983-02-23 Leo Ab Smoking substitutes
US4953572A (en) * 1985-04-25 1990-09-04 Rose Jed E Method and apparatus for aiding in the reduction of incidence of tobacco smoking
US4920989A (en) * 1985-04-25 1990-05-01 Regents Of The University Of California Method and apparatus for aiding in the reduction of incidence of tobacco smoking
US5474783A (en) * 1988-03-04 1995-12-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
US5135753A (en) * 1991-03-12 1992-08-04 Pharmetrix Corporation Method and therapeutic system for smoking cessation
GB9200047D0 (en) * 1992-01-03 1992-02-26 Univ Alberta Nicotine-containing nasal spray
RU2108089C1 (ru) * 1995-05-19 1998-04-10 Акционерное общество "Афродита" Шампунь для мытья волос
JP3707798B2 (ja) * 1996-05-13 2005-10-19 ノバルティス・コンシューマー・ヘルス・ソシエテ・アノニム 口内薬剤輸送系

Also Published As

Publication number Publication date
ES2332405T3 (es) 2010-02-04
JP5430525B2 (ja) 2014-03-05
CN1658876A (zh) 2005-08-24
JP4745658B2 (ja) 2011-08-10
EP1509227B1 (de) 2009-10-07
RU2283111C2 (ru) 2006-09-10
EP1509227A1 (de) 2005-03-02
AR039947A1 (es) 2005-03-09
WO2003101454A1 (en) 2003-12-11
NZ536863A (en) 2007-05-31
DE60329592D1 (de) 2009-11-19
CA2487699C (en) 2012-04-17
TW200407142A (en) 2004-05-16
JP2005533770A (ja) 2005-11-10
AU2003243074B2 (en) 2008-11-20
CN100500148C (zh) 2009-06-17
SE0201669D0 (sv) 2002-06-03
EP1509227B9 (de) 2010-05-19
ZA200409793B (en) 2006-08-30
CA2487699A1 (en) 2003-12-11
BR0311451A (pt) 2005-03-15
JP2010280721A (ja) 2010-12-16
IL165195A0 (en) 2005-12-18
AU2003243074A1 (en) 2003-12-19
MXPA04012041A (es) 2005-08-16
RU2004139067A (ru) 2005-08-10
DK1509227T3 (da) 2010-02-01

Similar Documents

Publication Publication Date Title
ATE444753T1 (de) Gepufferte flüssige nikotinzusammensetzung zur pulmonalen verabreichung
PL367180A1 (pl) Trwała kompozycja farmaceutyczna
ATE392863T1 (de) Streifen zur abgabe eines mundpflegewirkstoffes
ATE501135T1 (de) Piperidinamino-benzimidazol-derivate al respiratorisches syncytialvirus replikation inhibitoren
EP1743461A4 (de) Registrations-umlenk-server
MA29014B1 (fr) Formulations d'anticorps
FI20011478L (fi) Farmaseuttinen koostumus
DK1587478T3 (da) Farmaceutisk sammensætning
DE60138495D1 (de) Pharmazeutische Zusammensetzung Trehalose zur ophthalmischen Verwendung enthaltend
NO20050132D0 (no) Vaksinesammensetning
DK1467724T3 (da) Farmaceutisk sammensætning med agomelatin til dispergering i mundhulen
DE502004011765D1 (de) Implantat zur Spreizung der Nasenflügel
DE60333825D1 (de) Stabile faktor-viii enthaltende pharmazeutische zusammensetzung
FI20022128A0 (fi) Farmaseuttinen koostumus
NO20051956D0 (no) Salmeterol superfin formulering
NO20054662D0 (no) Farmasoytisk sammensetning omfattende 5-metyl-2-2'-(klor-6'-fluoranilin)fenyleddiksyre
NO20043489L (no) Sammensetning for inhalering
EP1559415A4 (de) Flüssige hautschutzzusammensetzung
EP1812794A4 (de) Autokrine wachstumsfaktor-rezeptoren und verfahren
ITMI20042356A1 (it) Composizione farmaceutica orodisperdibile e procedimento per prepararla
PL377147A1 (pl) Doustna kompozycja
NO20042027L (no) Oral composition
DK1653963T3 (da) Nasal farmaceutisk sammensætning piribedil
FR2866666B1 (fr) About d'echafaudage
ITMI20030826A1 (it) Composizione farmaceutica contenente interferone per il

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties