ATE445411T1 - Mva-exprimierende modifizierte hiv-envelope-, gag-und pol-gene - Google Patents

Mva-exprimierende modifizierte hiv-envelope-, gag-und pol-gene

Info

Publication number
ATE445411T1
ATE445411T1 AT02721259T AT02721259T ATE445411T1 AT E445411 T1 ATE445411 T1 AT E445411T1 AT 02721259 T AT02721259 T AT 02721259T AT 02721259 T AT02721259 T AT 02721259T AT E445411 T1 ATE445411 T1 AT E445411T1
Authority
AT
Austria
Prior art keywords
mva
gag
pol genes
hiv envelope
modified hiv
Prior art date
Application number
AT02721259T
Other languages
English (en)
Inventor
Bernard Moss
Linda Wyatt
Patricia Earl
Harriet Robinson
Original Assignee
Us Gov Health & Human Serv
Univ Emory
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Gov Health & Human Serv, Univ Emory filed Critical Us Gov Health & Human Serv
Application granted granted Critical
Publication of ATE445411T1 publication Critical patent/ATE445411T1/de

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/21—Retroviridae, e.g. equine infectious anemia virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • C12N2710/24011—Poxviridae
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    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
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    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
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    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2830/15—Vector systems having a special element relevant for transcription chimeric enhancer/promoter combination
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    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/60—Vector systems having a special element relevant for transcription from viruses

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AT02721259T 2001-03-08 2002-03-01 Mva-exprimierende modifizierte hiv-envelope-, gag-und pol-gene ATE445411T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27443401P 2001-03-08 2001-03-08
PCT/US2002/006713 WO2002072754A2 (en) 2001-03-08 2002-03-01 Mva expressing modified hiv envelope, gag, and pol genes

Publications (1)

Publication Number Publication Date
ATE445411T1 true ATE445411T1 (de) 2009-10-15

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AT02721259T ATE445411T1 (de) 2001-03-08 2002-03-01 Mva-exprimierende modifizierte hiv-envelope-, gag-und pol-gene

Country Status (13)

Country Link
US (4) US20040146528A1 (de)
EP (1) EP1372710B1 (de)
JP (2) JP4554887B2 (de)
CN (1) CN100446812C (de)
AT (1) ATE445411T1 (de)
AU (1) AU2002252199B2 (de)
CA (1) CA2454959C (de)
CY (1) CY1109659T1 (de)
DE (1) DE60234018D1 (de)
DK (1) DK1372710T3 (de)
ES (1) ES2334335T3 (de)
PT (1) PT1372710E (de)
WO (1) WO2002072754A2 (de)

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EP2337581B1 (de) * 2008-09-10 2017-08-23 Institut National De La Sante Et De La Recherche Medicale Synthetisches gen, das für das gag-protein von hiv-1 kodiert und dessen verwendung zur produktion von impfstoffe gegen hiv-1
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ES2606511T3 (es) 2011-04-06 2017-03-24 Biovaxim Limited Composiciones farmacéuticas para prevenir y/o tratar una enfermedad por VIH en seres humanos
WO2014018850A2 (en) * 2012-07-27 2014-01-30 The Trustees Of The University Of Pennsylvania Cytoplasmic tail modifications to boost surface expression and immunogenicity of envelope glycoproteins
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CN1638795A (zh) 2005-07-13
CA2454959C (en) 2018-07-10
US20040146528A1 (en) 2004-07-29
DE60234018D1 (de) 2009-11-26
JP4554887B2 (ja) 2010-09-29
US20090074726A1 (en) 2009-03-19
EP1372710B1 (de) 2009-10-14
JP2010115208A (ja) 2010-05-27
PT1372710E (pt) 2009-12-21
US8916172B2 (en) 2014-12-23
EP1372710A2 (de) 2004-01-02
WO2002072754A3 (en) 2003-05-22
US7867982B2 (en) 2011-01-11
CA2454959A1 (en) 2002-09-19
CY1109659T1 (el) 2014-08-13
EP1372710A4 (de) 2005-04-27
WO2002072754A9 (en) 2003-01-03
WO2002072754A2 (en) 2002-09-19
CN100446812C (zh) 2008-12-31
DK1372710T3 (da) 2010-01-18
US20150238593A1 (en) 2015-08-27
US20110104199A1 (en) 2011-05-05
JP2004537974A (ja) 2004-12-24
ES2334335T3 (es) 2010-03-09

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