ATE446086T1 - Herstellung von lipid-beschichtetem cefuroxime axetil - Google Patents

Herstellung von lipid-beschichtetem cefuroxime axetil

Info

Publication number: ATE446086T1
Authority: AT; Austria
Prior art keywords: lipid; cefuroxime axetil; mixture; lipids; preparation
Prior art date: 2004-03-19

Application number

AT04721911T

Other languages

English (en)

Inventor

Kadir Dabak

Adil Goeren

Cumhur Ulusoy

Timucin Oener

Seyfettin Soenmez

Guerkan Pembecioglu

Armagan Tanrikulu

Ibrahim Alper Uras

Refiye Tahir

Vahdet Ileri

Ibrahim Barin

Mete Demirel

Selim Kanbur

Semih Sucuoglu

Yunus Akyuez

Ece Pembecioglu

Original Assignee

Zentiva Kimyasal Ueruenler San

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-03-19

Filing date

2004-03-19

Publication date

2009-11-15

2004-03-19 Application filed by Zentiva Kimyasal Ueruenler San filed Critical Zentiva Kimyasal Ueruenler San

2009-11-15 Application granted granted Critical

2009-11-15 Publication of ATE446086T1 publication Critical patent/ATE446086T1/de

Links

KEJCWVGMRLCZQQ-YJBYXUATSA-N Cefuroxime axetil Chemical compound N([C@@H]1C(N2C(=C(COC(N)=O)CS[C@@H]21)C(=O)OC(C)OC(C)=O)=O)C(=O)\C(=N/OC)C1=CC=CO1 KEJCWVGMRLCZQQ-YJBYXUATSA-N 0.000 title abstract 6
229960002620 cefuroxime axetil Drugs 0.000 title abstract 6
150000002632 lipids Chemical class 0.000 abstract 9
239000000203 mixture Substances 0.000 abstract 4
238000000034 method Methods 0.000 abstract 2
239000002245 particle Substances 0.000 abstract 2
235000019658 bitter taste Nutrition 0.000 abstract 1
239000011248 coating agent Substances 0.000 abstract 1
238000000576 coating method Methods 0.000 abstract 1
238000001816 cooling Methods 0.000 abstract 1
239000012530 fluid Substances 0.000 abstract 1
238000007711 solidification Methods 0.000 abstract 1
230000008023 solidification Effects 0.000 abstract 1
239000000725 suspension Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5015—Organic compounds, e.g. fats, sugars
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine

Landscapes

Health & Medical Sciences (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Cephalosporin Compounds (AREA)

AT04721911T 2004-03-19 2004-03-19 Herstellung von lipid-beschichtetem cefuroxime axetil ATE446086T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/EP2004/050336 WO2005094791A1 (en)	2004-03-19	2004-03-19	Preparation of lipid coated cefuroxime axetil

Publications (1)

Publication Number	Publication Date
ATE446086T1 true ATE446086T1 (de)	2009-11-15

Family

ID=34957389

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT04721911T ATE446086T1 (de)	2004-03-19	2004-03-19	Herstellung von lipid-beschichtetem cefuroxime axetil

Country Status (5)

Country	Link
EP (1)	EP1727524B1 (de)
AT (1)	ATE446086T1 (de)
DE (1)	DE602004023764D1 (de)
TR (1)	TR200606412T2 (de)
WO (1)	WO2005094791A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2959130A1 (fr)	2010-04-21	2011-10-28	Sanofi Aventis	Procede de preparation de compositions pharmaceutiques destinees a l'administration par voie orale comprenant un ou plusieurs principes actifs et les compositions les comprenant.
WO2013024373A1 (en)	2011-08-12	2013-02-21	Dhanuka Laboratories Ltd.	Pharmaceutical composition comprising cefuroxime
CN105343011B (zh) *	2015-11-13	2019-03-15	青岛市海慈医疗集团	一种头孢呋辛酯颗粒剂的制备方法
CN110664779A (zh) *	2019-10-16	2020-01-10	山东鲁抗医药股份有限公司	一种头孢呋辛酯颗粒及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL193682C (nl) *	1987-05-14	2000-07-04	Glaxo Group Ltd	Beklede cefuroximaxetilsamenstelling.
US6248363B1 (en) *	1999-11-23	2001-06-19	Lipocine, Inc.	Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
ES2220789T3 (es) *	2000-10-30	2004-12-16	Lupin Limited	Composicion de cefuroxima axetilo de liberacion lenta que se desintegra rapidamente.
MXPA04008737A (es) *	2002-03-08	2005-07-13	M S Ind Swift Ltd	Complejos que se disuelven rapidamente, comprensibles directamente, insipidos, y formulaciones farmaceuticas de los mismos.

2004
- 2004-03-19 AT AT04721911T patent/ATE446086T1/de not_active IP Right Cessation
- 2004-03-19 TR TR2006/06412T patent/TR200606412T2/xx unknown
- 2004-03-19 WO PCT/EP2004/050336 patent/WO2005094791A1/en not_active Ceased
- 2004-03-19 EP EP04721911A patent/EP1727524B1/de not_active Expired - Lifetime
- 2004-03-19 DE DE602004023764T patent/DE602004023764D1/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP1727524B1 (de)	2009-10-21
EP1727524A1 (de)	2006-12-06
TR200606412T2 (tr)	2007-01-22
WO2005094791A1 (en)	2005-10-13
DE602004023764D1 (de)	2009-12-03

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Legal Events

Date	Code	Title	Description
2010-04-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties