ATE446086T1 - Herstellung von lipid-beschichtetem cefuroxime axetil - Google Patents
Herstellung von lipid-beschichtetem cefuroxime axetilInfo
- Publication number
- ATE446086T1 ATE446086T1 AT04721911T AT04721911T ATE446086T1 AT E446086 T1 ATE446086 T1 AT E446086T1 AT 04721911 T AT04721911 T AT 04721911T AT 04721911 T AT04721911 T AT 04721911T AT E446086 T1 ATE446086 T1 AT E446086T1
- Authority
- AT
- Austria
- Prior art keywords
- lipid
- cefuroxime axetil
- mixture
- lipids
- preparation
- Prior art date
Links
- KEJCWVGMRLCZQQ-YJBYXUATSA-N Cefuroxime axetil Chemical compound N([C@@H]1C(N2C(=C(COC(N)=O)CS[C@@H]21)C(=O)OC(C)OC(C)=O)=O)C(=O)\C(=N/OC)C1=CC=CO1 KEJCWVGMRLCZQQ-YJBYXUATSA-N 0.000 title abstract 6
- 229960002620 cefuroxime axetil Drugs 0.000 title abstract 6
- 150000002632 lipids Chemical class 0.000 abstract 9
- 239000000203 mixture Substances 0.000 abstract 4
- 238000000034 method Methods 0.000 abstract 2
- 239000002245 particle Substances 0.000 abstract 2
- 235000019658 bitter taste Nutrition 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 238000001816 cooling Methods 0.000 abstract 1
- 239000012530 fluid Substances 0.000 abstract 1
- 238000007711 solidification Methods 0.000 abstract 1
- 230000008023 solidification Effects 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5015—Organic compounds, e.g. fats, sugars
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2004/050336 WO2005094791A1 (en) | 2004-03-19 | 2004-03-19 | Preparation of lipid coated cefuroxime axetil |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE446086T1 true ATE446086T1 (de) | 2009-11-15 |
Family
ID=34957389
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04721911T ATE446086T1 (de) | 2004-03-19 | 2004-03-19 | Herstellung von lipid-beschichtetem cefuroxime axetil |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1727524B1 (de) |
| AT (1) | ATE446086T1 (de) |
| DE (1) | DE602004023764D1 (de) |
| TR (1) | TR200606412T2 (de) |
| WO (1) | WO2005094791A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2959130A1 (fr) | 2010-04-21 | 2011-10-28 | Sanofi Aventis | Procede de preparation de compositions pharmaceutiques destinees a l'administration par voie orale comprenant un ou plusieurs principes actifs et les compositions les comprenant. |
| EP2741750A1 (de) | 2011-08-12 | 2014-06-18 | Dhanuka Laboratories Ltd. | Pharmazeutische zusammensetzung mit cefuroxim |
| CN105343011B (zh) * | 2015-11-13 | 2019-03-15 | 青岛市海慈医疗集团 | 一种头孢呋辛酯颗粒剂的制备方法 |
| CN110664779A (zh) * | 2019-10-16 | 2020-01-10 | 山东鲁抗医药股份有限公司 | 一种头孢呋辛酯颗粒及其制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL193682C (nl) * | 1987-05-14 | 2000-07-04 | Glaxo Group Ltd | Beklede cefuroximaxetilsamenstelling. |
| US6248363B1 (en) * | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
| ATE266407T1 (de) * | 2000-10-30 | 2004-05-15 | Lupin Ltd | Schnell zerfallende cefuroxim axetil enthaltende arzneizusammensetzung mit verzögerter wirkstoffabgabe |
| AU2003209673B2 (en) * | 2002-03-08 | 2007-10-18 | M/S. Ind-Swift Limited | Tasteless directly compressible fast-dissolving complexes and pharmaceutical formulations thereof |
-
2004
- 2004-03-19 AT AT04721911T patent/ATE446086T1/de not_active IP Right Cessation
- 2004-03-19 TR TR2006/06412T patent/TR200606412T2/xx unknown
- 2004-03-19 EP EP04721911A patent/EP1727524B1/de not_active Expired - Lifetime
- 2004-03-19 DE DE602004023764T patent/DE602004023764D1/de not_active Expired - Lifetime
- 2004-03-19 WO PCT/EP2004/050336 patent/WO2005094791A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| DE602004023764D1 (de) | 2009-12-03 |
| EP1727524B1 (de) | 2009-10-21 |
| EP1727524A1 (de) | 2006-12-06 |
| TR200606412T2 (tr) | 2007-01-22 |
| WO2005094791A1 (en) | 2005-10-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |