ATE446091T1 - Basische nichtpeptid-bradykinin-antagonisten und pharmazeutische zusammensetzungen daraus - Google Patents

Basische nichtpeptid-bradykinin-antagonisten und pharmazeutische zusammensetzungen daraus

Info

Publication number: ATE446091T1
Authority: AT; Austria
Prior art keywords: pharmaceutical compositions; basic non; bradykinin antagonists; peptide bradykinin; peptide
Prior art date: 2002-06-07

Application number

AT03757025T

Other languages

English (en)

Inventor

Federico Calvani

Fernando Catrambone

Patrizia Felicetti

Christopher Fincham

Alessandro Giolitti

Carlo Maggi

Laura Quartara

Cristina Rossi

Rosa Terracciano

Original Assignee

Menarini Ricerche Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-06-07

Filing date

2003-06-05

Publication date

2009-11-15

2003-06-05 Application filed by Menarini Ricerche Spa filed Critical Menarini Ricerche Spa

2009-11-15 Application granted granted Critical

2009-11-15 Publication of ATE446091T1 publication Critical patent/ATE446091T1/de

Links

239000003152 bradykinin antagonist Substances 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Immunology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pulmonology (AREA)
Dermatology (AREA)
Urology & Nephrology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Oncology (AREA)
Orthopedic Medicine & Surgery (AREA)
Transplantation (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Communicable Diseases (AREA)
Vascular Medicine (AREA)
Physical Education & Sports Medicine (AREA)
Gastroenterology & Hepatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Quinoline Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT03757025T 2002-06-07 2003-06-05 Basische nichtpeptid-bradykinin-antagonisten und pharmazeutische zusammensetzungen daraus ATE446091T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT2002MI001247A ITMI20021247A1 (it)	2002-06-07	2002-06-07	Antagonisti basici non peptidici della bradichinina e loro impiego informulazioni farmaceutiche
PCT/EP2003/005893 WO2003103671A1 (en)	2002-06-07	2003-06-05	Basic non-peptide bradykinin antagonists and pharmaceutical compositions therefrom

Publications (1)

Publication Number	Publication Date
ATE446091T1 true ATE446091T1 (de)	2009-11-15

Family

ID=29727266

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03757025T ATE446091T1 (de)	2002-06-07	2003-06-05	Basische nichtpeptid-bradykinin-antagonisten und pharmazeutische zusammensetzungen daraus

Country Status (23)

Country	Link
US (1)	US7491825B2 (de)
EP (1)	EP1513531B1 (de)
JP (1)	JP4293988B2 (de)
CN (1)	CN1658877B (de)
AR (1)	AR040443A1 (de)
AT (1)	ATE446091T1 (de)
AU (1)	AU2003242628A1 (de)
BR (1)	BR0311825A (de)
CA (1)	CA2488565C (de)
CY (1)	CY1109543T1 (de)
DE (1)	DE60329755D1 (de)
DK (1)	DK1513531T3 (de)
EG (1)	EG26672A (de)
ES (1)	ES2332509T3 (de)
IT (1)	ITMI20021247A1 (de)
MX (1)	MXPA04012193A (de)
PL (1)	PL224990B1 (de)
PT (1)	PT1513531E (de)
RU (1)	RU2327688C2 (de)
SA (1)	SA03240198B1 (de)
SI (1)	SI1513531T1 (de)
TW (1)	TWI315983B (de)
WO (1)	WO2003103671A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP4324480B2 (ja) *	2002-03-26	2009-09-02	ベーリンガーインゲルハイムファーマシューティカルズインコーポレイテッド	グルココルチコイドミメティクス、その製法、医薬組成物、及び使用
NZ538932A (en) *	2002-08-29	2007-04-27	Boehringer Ingelheim Pharma	3-(sulfonamidoethyl)-indole derivatives for use as glucocorticoid mimetics in the treatment of inflammatory, allergic and proliferative disease
UY28526A1 (es) *	2003-09-24	2005-04-29	Boehringer Ingelheim Pharma	Miméticos de glucocorticoides, métodos de preparación composiciones farmacéuticas y usos de los mismos
US7795272B2 (en) *	2004-03-13	2010-09-14	Boehringer Ingelheim Pharmaceutical, Inc.	Glucocorticoid mimetics, methods of making them, pharmaceutical compositions and uses thereof
ITMI20041963A1 (it) *	2004-10-15	2005-01-15	Luso Farmaco Inst	"antagonisti non-peptidici della bradichinina e loro composizioni farmaceutiche"
PE20060776A1 (es) *	2004-12-27	2006-09-26	Boehringer Ingelheim Pharma	Mimeticos de glucocorticoides, metodos para prepararlos y composiciones farmaceuticas
WO2007115805A2 (en) *	2006-04-05	2007-10-18	European Molecular Biology Laboratory (Embl)	Aurora kinase inhibitors
EP2086935A1 (de)	2006-10-16	2009-08-12	Grünenthal GmbH	Substituierte sulfonamid-derivate als bradykinin 1 rezeptor modulatoren
MX2009005264A (es) *	2006-12-06	2009-05-28	Boehringer Ingelheim Int	Mimeticos de glucocorticoides, metodos para su fabricacion, composiciones farmaceuticas y usos de los mismos.
TWI407960B (zh)	2007-03-23	2013-09-11	Jerini Ag	小分子緩激肽ｂ２受體調節劑
US20100063282A1 (en) *	2007-04-10	2010-03-11	Boehringer Ingelheim International Gmbh	Glucocorticoid Mimetics, Methods of Making Them, Pharmaceutical Compositions, and Uses Thereof
ITMI20072225A1 (it) *	2007-11-23	2009-05-24	Luso Farmaco Inst	"composizioni farmaceutiche a base di antagonisti della bradichinina ed acido ialuronico e loro uso"
DK2300472T3 (da) *	2008-06-06	2012-04-10	Boehringer Ingelheim Int	Glucocorticoidmimetika, fremgangsmåder til disses fremstilling, farmaceutiske sammensætninger samt anvendelser deraf
IT1391236B1 (it) *	2008-07-11	2011-12-01	St Luso Farm D'italia Spa	Composizioni farmaceutiche a base di antagonisti del recettore b2 delle chinine e corticosteroidi e loro uso
SMT202200154T1 (it)	2017-11-24	2022-05-12	Pharvaris Netherlands B V	Nuovi antagonisti del recettore della bradichinina b2
AR118983A1 (es)	2019-05-23	2021-11-17	Pharvaris Gmbh	Antagonistas cíclicos del receptor b2 de bradiquinina
UY38706A (es)	2019-05-23	2020-12-31	Pharvaris Gmbh	Antagonistas cíclicos del receptor b2 de bradiquinina
TW202345810A (zh)	2022-03-25	2023-12-01	瑞士商帕法瑞斯有限責任公司	包含緩激肽ｂ２受體拮抗劑之固態延長釋放組成物
WO2023180577A1 (en)	2022-03-25	2023-09-28	Pharvaris Gmbh	Therapeutic uses of bradykinin b2-receptor antagonists
HRP20260166T1 (hr)	2022-03-25	2026-03-27	Pharvaris Gmbh	Čvrsti sastav koji sadrži solubilizirane antagoniste bradikinin b2 receptora

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU680870B2 (en) *	1993-04-28	1997-08-14	Astellas Pharma Inc.	New heterocyclic compounds
FR2735128B1 (fr)	1995-06-07	1997-07-25	Fournier Ind & Sante	Nouveaux composes de benzenesulfonamide, leur procede de preparation et utilisation en therapeutique.
DE19609827A1 (de) *	1996-03-13	1997-09-18	Hoechst Ag	Aminoalkyl- und Acylaminoalkylether, Verfahren zu deren Herstellung und ihre Verwendung als Bradykinin-Rezeptorantagonisten
DE19610784A1 (de) *	1996-03-19	1997-09-25	Hoechst Ag	Fluoralkyl- und Fluoralkoxysubstituierte heterocyclische Bradykinin-Antagonisten, Verfahren zu ihrer Herstellung und ihre Verwendung
FR2751650B1 (fr)	1996-07-24	1998-10-09	Fournier Ind & Sante	Nouveaux composes de n-benzenesulfonyl-l-proline, procede de preparation et utilisation en therapeutique
FR2756562B1 (fr) *	1996-12-04	1999-01-08	Fournier Ind & Sante	Nouveaux composes de n-benzenesulfonyl-l-proline, procede de preparation et utilisation en therapeutique
DE19712960A1 (de) *	1997-03-27	1998-10-01	Hoechst Ag	Benzyloxy-substituierte, anellierte N-Heterocyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Bradykininrezeptorantagonisten

2002
- 2002-06-07 IT IT2002MI001247A patent/ITMI20021247A1/it unknown
2003
- 2003-06-04 EG EG2003060535A patent/EG26672A/en active
- 2003-06-05 PT PT03757025T patent/PT1513531E/pt unknown
- 2003-06-05 JP JP2004510790A patent/JP4293988B2/ja not_active Expired - Fee Related
- 2003-06-05 RU RU2004135567/04A patent/RU2327688C2/ru not_active IP Right Cessation
- 2003-06-05 DE DE60329755T patent/DE60329755D1/de not_active Expired - Lifetime
- 2003-06-05 EP EP03757025A patent/EP1513531B1/de not_active Expired - Lifetime
- 2003-06-05 AT AT03757025T patent/ATE446091T1/de active
- 2003-06-05 AR AR20030102009A patent/AR040443A1/es not_active Application Discontinuation
- 2003-06-05 US US10/516,681 patent/US7491825B2/en not_active Expired - Fee Related
- 2003-06-05 SI SI200331698T patent/SI1513531T1/sl unknown
- 2003-06-05 CN CN038130270A patent/CN1658877B/zh not_active Expired - Fee Related
- 2003-06-05 AU AU2003242628A patent/AU2003242628A1/en not_active Abandoned
- 2003-06-05 ES ES03757025T patent/ES2332509T3/es not_active Expired - Lifetime
- 2003-06-05 MX MXPA04012193A patent/MXPA04012193A/es active IP Right Grant
- 2003-06-05 TW TW092115212A patent/TWI315983B/zh not_active IP Right Cessation
- 2003-06-05 DK DK03757025.6T patent/DK1513531T3/da active
- 2003-06-05 BR BR0311825-8A patent/BR0311825A/pt not_active Application Discontinuation
- 2003-06-05 CA CA2488565A patent/CA2488565C/en not_active Expired - Fee Related
- 2003-06-05 WO PCT/EP2003/005893 patent/WO2003103671A1/en not_active Ceased
- 2003-06-05 PL PL373466A patent/PL224990B1/pl unknown
- 2003-07-12 SA SA3240198A patent/SA03240198B1/ar unknown
2009
- 2009-12-03 CY CY20091101272T patent/CY1109543T1/el unknown

Also Published As

Publication number	Publication date
US7491825B2 (en)	2009-02-17
MXPA04012193A (es)	2005-02-25
EP1513531A1 (de)	2005-03-16
RU2004135567A (ru)	2005-07-20
DK1513531T3 (da)	2010-01-18
DE60329755D1 (de)	2009-12-03
US20060205712A1 (en)	2006-09-14
AR040443A1 (es)	2005-04-06
CN1658877B (zh)	2010-04-28
EG26672A (en)	2014-05-13
WO2003103671A8 (en)	2004-12-29
BR0311825A (pt)	2005-03-15
TWI315983B (en)	2009-10-21
SI1513531T1 (sl)	2010-01-29
JP2005532354A (ja)	2005-10-27
CY1109543T1 (el)	2014-08-13
WO2003103671A1 (en)	2003-12-18
PL373466A1 (en)	2005-09-05
RU2327688C2 (ru)	2008-06-27
PL224990B1 (pl)	2017-02-28
EP1513531B1 (de)	2009-10-21
PT1513531E (pt)	2009-12-17
CA2488565C (en)	2012-01-03
TW200400819A (en)	2004-01-16
AU2003242628A1 (en)	2003-12-22
ITMI20021247A1 (it)	2003-12-09
ES2332509T3 (es)	2010-02-08
CN1658877A (zh)	2005-08-24
CA2488565A1 (en)	2003-12-18
SA03240198B1 (ar)	2009-12-08
JP4293988B2 (ja)	2009-07-08

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2010-03-15

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Publication	Publication Date	Title
NO2023030I1 (no)	2023-08-17	Apixaban and pharmaceutical acceptable salts thereof
DE60329755D1 (de)	2009-12-03	Basische nichtpeptid-bradykinin-antagonisten und pharmazeutische zusammensetzungen daraus
DE60307677D1 (de)	2006-09-28	Dispergierbare pharmazeutische zusammensetzungen
EP1458362A4 (de)	2006-01-18	Pharmazeutische zusammensetzungen in teilchenform
NO20033384L (no)	2003-09-25	Farmasoytisk formulering
PT1501534E (pt)	2006-09-29	Formulacoes farmaceuticas
NO20033785L (no)	2003-10-24	Farmasöytisk formulering
DE60319951D1 (de)	2008-05-08	Aminocyclische substituierte pyrrolopyrimidinderivate und pyrrolopyridinderivate
MA29007B1 (fr)	2007-11-01	Antagonistes de bradykinine non-peptidiques et compositions pharmaceutiques constituees de ces composes
PT1467724E (pt)	2006-08-31	Composicao farmaceutica orodispersavel de agomelatina
DK3494995T3 (da)	2020-03-23	Superfin formoterolformulering
NO20035627D0 (no)	2003-12-15	Farmasöytisk formulering
DE60217390D1 (de)	2007-02-15	Bicalutamid enthaltende pharmazeutische zusammensetzung
NO20044164L (no)	2004-09-30	Farmasoytiske sammensetninger
DE10107261B4 (de)	2005-03-10	Pharmazeutische Zusammensetzung
DE602004012241D1 (de)	2008-04-17	Polymere modifizierungsmittel und pharmazeutische zusammensetzungen
SE0200449D0 (sv)	2002-02-13	Pharmaceutical formulation
SE0201660D0 (sv)	2002-05-31	Pharmaceutical formulation
NO20041236L (no)	2004-03-24	Farmasoytisk formulering
ITMI20020926A1 (it)	2003-10-30	Composizioni farmaceutiche riepitelizzanti
DE602004030921D1 (de)	2011-02-17	Pharmazeutische zusammensetzung
ITMI20021127A0 (it)	2002-05-24	Composizioni farmaceutiche oromucosali
SE0102957D0 (sv)	2001-09-04	Pharmaceutical formulation
SE0101171D0 (sv)	2001-04-02	Pharmaceutical formulation
SE0102572D0 (sv)	2001-07-19	Pharmaceutical formulation