ITMI20021247A1 - Antagonisti basici non peptidici della bradichinina e loro impiego informulazioni farmaceutiche - Google Patents

Antagonisti basici non peptidici della bradichinina e loro impiego informulazioni farmaceutiche

Info

Publication number
ITMI20021247A1
ITMI20021247A1 IT2002MI001247A ITMI20021247A ITMI20021247A1 IT MI20021247 A1 ITMI20021247 A1 IT MI20021247A1 IT 2002MI001247 A IT2002MI001247 A IT 2002MI001247A IT MI20021247 A ITMI20021247 A IT MI20021247A IT MI20021247 A1 ITMI20021247 A1 IT MI20021247A1
Authority
IT
Italy
Prior art keywords
bradichinine
peptid
antagonists
basic
use pharmaceutical
Prior art date
Application number
IT2002MI001247A
Other languages
English (en)
Inventor
Cristina Rossi
Alessandro Giolitti
Carlo Alberto Maggi
Federico Calvani
Fernando Catrambone
Patrizia Felicetti
Christopher Ingo Fincham
Laura Quartara
Rosa Terraciano
Original Assignee
Menarini Ricerche Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Ricerche Spa filed Critical Menarini Ricerche Spa
Priority to IT2002MI001247A priority Critical patent/ITMI20021247A1/it
Priority to EG2003060535A priority patent/EG26672A/en
Priority to PT03757025T priority patent/PT1513531E/pt
Priority to AU2003242628A priority patent/AU2003242628A1/en
Priority to PCT/EP2003/005893 priority patent/WO2003103671A1/en
Priority to ES03757025T priority patent/ES2332509T3/es
Priority to AT03757025T priority patent/ATE446091T1/de
Priority to JP2004510790A priority patent/JP4293988B2/ja
Priority to RU2004135567/04A priority patent/RU2327688C2/ru
Priority to AR20030102009A priority patent/AR040443A1/es
Priority to CA2488565A priority patent/CA2488565C/en
Priority to PL373466A priority patent/PL224990B1/pl
Priority to US10/516,681 priority patent/US7491825B2/en
Priority to SI200331698T priority patent/SI1513531T1/sl
Priority to TW092115212A priority patent/TWI315983B/zh
Priority to BR0311825-8A priority patent/BR0311825A/pt
Priority to CN038130270A priority patent/CN1658877B/zh
Priority to DE60329755T priority patent/DE60329755D1/de
Priority to DK03757025.6T priority patent/DK1513531T3/da
Priority to MXPA04012193A priority patent/MXPA04012193A/es
Priority to EP03757025A priority patent/EP1513531B1/en
Priority to SA3240198A priority patent/SA03240198B1/ar
Publication of ITMI20021247A1 publication Critical patent/ITMI20021247A1/it
Priority to CY20091101272T priority patent/CY1109543T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Communicable Diseases (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Quinoline Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IT2002MI001247A 2002-06-07 2002-06-07 Antagonisti basici non peptidici della bradichinina e loro impiego informulazioni farmaceutiche ITMI20021247A1 (it)

Priority Applications (23)

Application Number Priority Date Filing Date Title
IT2002MI001247A ITMI20021247A1 (it) 2002-06-07 2002-06-07 Antagonisti basici non peptidici della bradichinina e loro impiego informulazioni farmaceutiche
EG2003060535A EG26672A (en) 2002-06-07 2003-06-04 Non-peptide-based bradykinin antagonists and pharmaceutical compounds thereof
PL373466A PL224990B1 (pl) 2002-06-07 2003-06-05 Niepeptydowi antagoniści bradykininy o charakterze zasadowym i ich zastosowanie, kompozycje farmaceutyczne oraz związki pośrednie
SI200331698T SI1513531T1 (sl) 2002-06-07 2003-06-05 Baziäśni nepeptidni antagonisti bradikinina in farmacevtski sestavki iz njih
PCT/EP2003/005893 WO2003103671A1 (en) 2002-06-07 2003-06-05 Basic non-peptide bradykinin antagonists and pharmaceutical compositions therefrom
ES03757025T ES2332509T3 (es) 2002-06-07 2003-06-05 Antagonistas de bradicinina no peptidicos basicos y composiciones farmaceuticas de los mismos.
AT03757025T ATE446091T1 (de) 2002-06-07 2003-06-05 Basische nichtpeptid-bradykinin-antagonisten und pharmazeutische zusammensetzungen daraus
JP2004510790A JP4293988B2 (ja) 2002-06-07 2003-06-05 塩基性非ペプチド性ブラジキニンアンタゴニスト及びそれから得られた医薬組成物
RU2004135567/04A RU2327688C2 (ru) 2002-06-07 2003-06-05 Основные непептидные антагонисты брадикинина и их фармацевтические композиции
AR20030102009A AR040443A1 (es) 2002-06-07 2003-06-05 Antagonistas basicos no peptidicos de la bradiquinina y composiciones farmaceuticas de los mismos
CA2488565A CA2488565C (en) 2002-06-07 2003-06-05 Basic non-peptide bradykinin antagonists and pharmaceutical compositions therefrom
PT03757025T PT1513531E (pt) 2002-06-07 2003-06-05 Antagonistas de bradicinina não peptídicos básicos e composições farmacêuticas dos mesmos
US10/516,681 US7491825B2 (en) 2002-06-07 2003-06-05 Basic non-peptide bradykinin antagonists and pharmaceutical compositions therefrom
AU2003242628A AU2003242628A1 (en) 2002-06-07 2003-06-05 Basic non-peptide bradykinin antagonists and pharmaceutical compositions therefrom
TW092115212A TWI315983B (en) 2002-06-07 2003-06-05 Basic non-peptide bradykinin antagonists and pharmaceutical compositions therefrom
BR0311825-8A BR0311825A (pt) 2002-06-07 2003-06-05 Antagonistas de bradicinina de não-peptìdeo básicos e composições farmacêuticas dos mesmos
CN038130270A CN1658877B (zh) 2002-06-07 2003-06-05 碱性非肽缓激肽拮抗剂及其药物组合物
DE60329755T DE60329755D1 (de) 2002-06-07 2003-06-05 Basische nichtpeptid-bradykinin-antagonisten und pharmazeutische zusammensetzungen daraus
DK03757025.6T DK1513531T3 (da) 2002-06-07 2003-06-05 Basisk non-peptide bradykinin antagonister og farmaceutiske sammensætninger deraf
MXPA04012193A MXPA04012193A (es) 2002-06-07 2003-06-05 Antagonistas de bradicinina no peptidico, basicos y composiciones farmaceuticas de estos.
EP03757025A EP1513531B1 (en) 2002-06-07 2003-06-05 Basic non-peptide bradykinin antagonists and pharmaceutical compositions therefrom
SA3240198A SA03240198B1 (ar) 2002-06-07 2003-07-12 مضادات براديكينين قاعدية غير ببتيدية وتركيبات صيدلانية منها
CY20091101272T CY1109543T1 (el) 2002-06-07 2009-12-03 Βασικοι μη-πεπτιδικοι ανταγωνιστες βραδυκινινης και 5 φαρμακευτικες συνθεσεις απο αυτους

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2002MI001247A ITMI20021247A1 (it) 2002-06-07 2002-06-07 Antagonisti basici non peptidici della bradichinina e loro impiego informulazioni farmaceutiche

Publications (1)

Publication Number Publication Date
ITMI20021247A1 true ITMI20021247A1 (it) 2003-12-09

Family

ID=29727266

Family Applications (1)

Application Number Title Priority Date Filing Date
IT2002MI001247A ITMI20021247A1 (it) 2002-06-07 2002-06-07 Antagonisti basici non peptidici della bradichinina e loro impiego informulazioni farmaceutiche

Country Status (23)

Country Link
US (1) US7491825B2 (it)
EP (1) EP1513531B1 (it)
JP (1) JP4293988B2 (it)
CN (1) CN1658877B (it)
AR (1) AR040443A1 (it)
AT (1) ATE446091T1 (it)
AU (1) AU2003242628A1 (it)
BR (1) BR0311825A (it)
CA (1) CA2488565C (it)
CY (1) CY1109543T1 (it)
DE (1) DE60329755D1 (it)
DK (1) DK1513531T3 (it)
EG (1) EG26672A (it)
ES (1) ES2332509T3 (it)
IT (1) ITMI20021247A1 (it)
MX (1) MXPA04012193A (it)
PL (1) PL224990B1 (it)
PT (1) PT1513531E (it)
RU (1) RU2327688C2 (it)
SA (1) SA03240198B1 (it)
SI (1) SI1513531T1 (it)
TW (1) TWI315983B (it)
WO (1) WO2003103671A1 (it)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL373043A1 (en) * 2002-03-26 2005-08-08 Boehringer Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
JP4619786B2 (ja) * 2002-08-29 2011-01-26 ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド 炎症性、アレルギー性及び増殖性疾患の治療において糖質コルチコイドミメティックスとして使用するための３−（スルホンアミドエチル）−インドール誘導体
UY28526A1 (es) * 2003-09-24 2005-04-29 Boehringer Ingelheim Pharma Miméticos de glucocorticoides, métodos de preparación composiciones farmacéuticas y usos de los mismos
US7795272B2 (en) * 2004-03-13 2010-09-14 Boehringer Ingelheim Pharmaceutical, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions and uses thereof
ITMI20041963A1 (it) * 2004-10-15 2005-01-15 Luso Farmaco Inst "antagonisti non-peptidici della bradichinina e loro composizioni farmaceutiche"
US7635711B2 (en) * 2004-12-27 2009-12-22 Boehringer-Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
WO2007115805A2 (en) * 2006-04-05 2007-10-18 European Molecular Biology Laboratory (Embl) Aurora kinase inhibitors
EP2086935A1 (de) 2006-10-16 2009-08-12 Grünenthal GmbH Substituierte sulfonamid-derivate als bradykinin 1 rezeptor modulatoren
MX2009005264A (es) * 2006-12-06 2009-05-28 Boehringer Ingelheim Int Mimeticos de glucocorticoides, metodos para su fabricacion, composiciones farmaceuticas y usos de los mismos.
TWI407960B (zh) 2007-03-23 2013-09-11 Jerini Ag 小分子緩激肽ｂ２受體調節劑
JP2010523689A (ja) * 2007-04-10 2010-07-15 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング グルココルチコイドミメティックス、その製造方法、医薬組成物及びその使用
ITMI20072225A1 (it) * 2007-11-23 2009-05-24 Luso Farmaco Inst "composizioni farmaceutiche a base di antagonisti della bradichinina ed acido ialuronico e loro uso"
ATE541846T1 (de) * 2008-06-06 2012-02-15 Boehringer Ingelheim Int Glucocorticoidmimetika, verfahren zu deren herstellung, pharmazeutische zusammensetzungen und anwendungen davon
IT1391236B1 (it) * 2008-07-11 2011-12-01 St Luso Farm D'italia Spa Composizioni farmaceutiche a base di antagonisti del recettore b2 delle chinine e corticosteroidi e loro uso
IL274883B2 (en) 2017-11-24 2023-11-01 Pharvaris Netherlands B V BRADYKININ B2 receptor antagonists
AR118982A1 (es) 2019-05-23 2021-11-17 Pharvaris Gmbh Antagonistas cíclicos del receptor b2 de bradiquinina
UY38707A (es) 2019-05-23 2020-12-31 Pharvaris Gmbh Nuevos antagonistas cíclicos del receptor b2 de bradiquinina
EP4499100A1 (en) 2022-03-25 2025-02-05 Pharvaris GmbH Therapeutic uses of bradykinin b2-receptor antagonists
TW202345810A (zh) 2022-03-25 2023-12-01 瑞士商帕法瑞斯有限責任公司 包含緩激肽ｂ２受體拮抗劑之固態延長釋放組成物
HRP20260166T1 (hr) 2022-03-25 2026-03-27 Pharvaris Gmbh Čvrsti sastav koji sadrži solubilizirane antagoniste bradikinin b2 receptora

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AU680870B2 (en) * 1993-04-28 1997-08-14 Astellas Pharma Inc. New heterocyclic compounds
FR2735128B1 (fr) 1995-06-07 1997-07-25 Fournier Ind & Sante Nouveaux composes de benzenesulfonamide, leur procede de preparation et utilisation en therapeutique.
DE19609827A1 (de) * 1996-03-13 1997-09-18 Hoechst Ag Aminoalkyl- und Acylaminoalkylether, Verfahren zu deren Herstellung und ihre Verwendung als Bradykinin-Rezeptorantagonisten
DE19610784A1 (de) * 1996-03-19 1997-09-25 Hoechst Ag Fluoralkyl- und Fluoralkoxysubstituierte heterocyclische Bradykinin-Antagonisten, Verfahren zu ihrer Herstellung und ihre Verwendung
FR2751650B1 (fr) 1996-07-24 1998-10-09 Fournier Ind & Sante Nouveaux composes de n-benzenesulfonyl-l-proline, procede de preparation et utilisation en therapeutique
FR2756562B1 (fr) * 1996-12-04 1999-01-08 Fournier Ind & Sante Nouveaux composes de n-benzenesulfonyl-l-proline, procede de preparation et utilisation en therapeutique
DE19712960A1 (de) * 1997-03-27 1998-10-01 Hoechst Ag Benzyloxy-substituierte, anellierte N-Heterocyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Bradykininrezeptorantagonisten

Also Published As

Publication number Publication date
TW200400819A (en) 2004-01-16
RU2004135567A (ru) 2005-07-20
CN1658877A (zh) 2005-08-24
RU2327688C2 (ru) 2008-06-27
CN1658877B (zh) 2010-04-28
EP1513531B1 (en) 2009-10-21
CY1109543T1 (el) 2014-08-13
EP1513531A1 (en) 2005-03-16
WO2003103671A1 (en) 2003-12-18
EG26672A (en) 2014-05-13
JP4293988B2 (ja) 2009-07-08
PL373466A1 (en) 2005-09-05
US20060205712A1 (en) 2006-09-14
MXPA04012193A (es) 2005-02-25
AR040443A1 (es) 2005-04-06
DE60329755D1 (de) 2009-12-03
CA2488565A1 (en) 2003-12-18
AU2003242628A1 (en) 2003-12-22
ATE446091T1 (de) 2009-11-15
BR0311825A (pt) 2005-03-15
PL224990B1 (pl) 2017-02-28
DK1513531T3 (da) 2010-01-18
PT1513531E (pt) 2009-12-17
TWI315983B (en) 2009-10-21
ES2332509T3 (es) 2010-02-08
CA2488565C (en) 2012-01-03
US7491825B2 (en) 2009-02-17
SI1513531T1 (sl) 2010-01-29
WO2003103671A8 (en) 2004-12-29
SA03240198B1 (ar) 2009-12-08
JP2005532354A (ja) 2005-10-27

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