ATE44621T1 - Proteinkonjugate von penicillosaeure, ihre herstellung und verwendung. - Google Patents

Proteinkonjugate von penicillosaeure, ihre herstellung und verwendung.

Info

Publication number: ATE44621T1
Authority: AT; Austria
Prior art keywords: production; penicillo; acid; protein conjugates; amino acids
Prior art date: 1983-11-02

Application number

AT84307549T

Other languages

English (en)

Inventor

Prithipal Singh

Richard Rodgers

Danton K Leung

Original Assignee

Syntex Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-11-02

Filing date

1984-11-01

Publication date

1989-07-15

1984-11-01 Application filed by Syntex Inc filed Critical Syntex Inc

1989-07-15 Application granted granted Critical

1989-07-15 Publication of ATE44621T1 publication Critical patent/ATE44621T1/de

Links

239000002253 acid Substances 0.000 title 1
102000004169 proteins and genes Human genes 0.000 title 1
108090000623 proteins and genes Proteins 0.000 title 1
OPEGYZAATHKDEM-HCWXCVPCSA-N (2r,4s)-2-[(r)-carboxy(formamido)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid Chemical class CC1(C)S[C@H]([C@H](NC=O)C(O)=O)N[C@H]1C(O)=O OPEGYZAATHKDEM-HCWXCVPCSA-N 0.000 abstract 2
230000000890 antigenic effect Effects 0.000 abstract 2
-1 poly(amino acids) Polymers 0.000 abstract 2
229920001308 poly(aminoacid) Polymers 0.000 abstract 2
108090000204 Dipeptidase 1 Proteins 0.000 abstract 1
102000004190 Enzymes Human genes 0.000 abstract 1
108090000790 Enzymes Proteins 0.000 abstract 1
229930182555 Penicillin Natural products 0.000 abstract 1
JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 abstract 1
102000006635 beta-lactamase Human genes 0.000 abstract 1
239000003153 chemical reaction reagent Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000002255 enzymatic effect Effects 0.000 abstract 1
238000003018 immunoassay Methods 0.000 abstract 1
229940049954 penicillin Drugs 0.000 abstract 1
210000002966 serum Anatomy 0.000 abstract 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/9446—Antibacterials
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/535—Production of labelled immunochemicals with enzyme label or co-enzymes, co-factors, enzyme inhibitors or enzyme substrates
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/805—Test papers
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/961—Chemistry: molecular biology and microbiology including a step of forming, releasing, or exposing the antigen or forming the hapten-immunogenic carrier complex or the antigen per se
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/964—Chemistry: molecular biology and microbiology including enzyme-ligand conjugate production, e.g. reducing rate of nonproductive linkage
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
- Y10S436/81—Tube, bottle, or dipstick
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/815—Test for named compound or class of compounds
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/822—Identified hapten
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/807—Hapten conjugated with peptide or protein

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Molecular Biology (AREA)
Urology & Nephrology (AREA)
Hematology (AREA)
Biomedical Technology (AREA)
Chemical & Material Sciences (AREA)
Physics & Mathematics (AREA)
Biochemistry (AREA)
Microbiology (AREA)
Pathology (AREA)
Cell Biology (AREA)
Food Science & Technology (AREA)
Medicinal Chemistry (AREA)
Biotechnology (AREA)
Analytical Chemistry (AREA)
General Physics & Mathematics (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT84307549T 1983-11-02 1984-11-01 Proteinkonjugate von penicillosaeure, ihre herstellung und verwendung. ATE44621T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US06/548,164 US4596768A (en)	1983-11-02	1983-11-02	Antibodies for penicilloic acid their preparation and use
EP84307549A EP0144154B1 (de)	1983-11-02	1984-11-01	Proteinkonjugate von Penicillosäure, ihre Herstellung und Verwendung

Publications (1)

Publication Number	Publication Date
ATE44621T1 true ATE44621T1 (de)	1989-07-15

Family

ID=24187683

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT84307549T ATE44621T1 (de)	1983-11-02	1984-11-01	Proteinkonjugate von penicillosaeure, ihre herstellung und verwendung.

Country Status (6)

Country	Link
US (1)	US4596768A (de)
EP (1)	EP0144154B1 (de)
JP (1)	JPH0731192B2 (de)
AT (1)	ATE44621T1 (de)
CA (1)	CA1227446A (de)
DE (1)	DE3478958D1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4762782A (en) *	1985-05-16	1988-08-09	Micromol Corporation	Assay for Beta-lactam antibiotics
US4786594A (en) *	1986-05-14	1988-11-22	Syntex (U.S.A.) Inc.	Enzyme immunoassay
US4921791A (en) *	1986-06-26	1990-05-01	Konishiroku Photo Industry Co., Ltd.	Method for measuring specific component using peroxidase enzyme reaction
US5166078A (en) *	1986-08-19	1992-11-24	Idexx Laboratories, Inc.	Hapten-macromolecule conjugates useful in hapten assays
GB8722470D0 (en) *	1987-09-24	1987-10-28	Blackmore D J	Production of anti-genic protein-hapten conjugates
US5229267A (en) *	1991-08-26	1993-07-20	Merck & Co., Inc.	Assay for evaluating inhibition of PMN elastase by N-substituted azetidinones
US5274080A (en) *	1991-08-26	1993-12-28	Merck & Co., Inc.	Monospecific antibodies useful in evaluating inhibition of polymorphonuclear leukocyte elastase by N-substituted azetidinones
US5420010A (en) *	1993-07-30	1995-05-30	Merck & Co., Inc.	Assay for evaluating inhibition of polymorphonuclear leukocyte elastase by N-substituted azetidinones
US6153381A (en) *	1997-08-28	2000-11-28	Millennium Pharmaceuticals, Inc.	Screening for antibiotics
EP1281971B1 (de) *	2001-08-02	2005-11-02	Randox Laboratories Ltd.	Verfahren und Kit zur Quantifizierung von Beta-Laktam Penizillinen
EP2621535A1 (de) *	2010-09-29	2013-08-07	Philogen S.p.A.	Thiazolidinlinker für die konjugation von wirkstoffen an antikörper
US20180156796A1 (en) *	2016-12-06	2018-06-07	Silver Lake Research Corporation	Methods of Detection of Antibiotic-Resistant Bacteria

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1226773A (de) *	1967-07-27	1971-03-31
DE2742507A1 (de) *	1976-09-28	1978-03-30	Alain De Prof Dr Weck	Polypeptidderivate und verfahren zu deren herstellung
US4239852A (en) *	1978-06-12	1980-12-16	Penicillin Assays, Inc.	Antibiotic detection method
US4234683A (en) *	1978-11-24	1980-11-18	Mcmillan William A	Beta-lactamase diagnostic product and method
US4347312A (en) *	1980-03-20	1982-08-31	Research Triangle Institute	Detection of antibiotics in milk

1983
- 1983-11-02 US US06/548,164 patent/US4596768A/en not_active Expired - Lifetime
1984
- 1984-10-31 CA CA000466727A patent/CA1227446A/en not_active Expired
- 1984-11-01 DE DE8484307549T patent/DE3478958D1/de not_active Expired
- 1984-11-01 EP EP84307549A patent/EP0144154B1/de not_active Expired
- 1984-11-01 AT AT84307549T patent/ATE44621T1/de not_active IP Right Cessation
- 1984-11-01 JP JP59232249A patent/JPH0731192B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP0144154B1 (de)	1989-07-12
JPH0731192B2 (ja)	1995-04-10
US4596768A (en)	1986-06-24
EP0144154A1 (de)	1985-06-12
DE3478958D1 (en)	1989-08-17
JPS60166700A (ja)	1985-08-29
CA1227446A (en)	1987-09-29

Legal Events

Date	Code	Title	Description
1990-01-15	UEP	Publication of translation of european patent specification
1991-08-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ES2045216T3 (es)	1994-01-16	Inmunoensayo y derivados polimeros de igg para la compensacion de factores de perturbacion en el inmunoensayo.
FI98569B (fi)	1997-03-27	Heteropolyhapon vaikealiukoisen suolan käyttö analyytin määritykseen, vastaava määritysmenetelmä sekä tähän sopiva aine
ATE21173T1 (de)	1986-08-15	Methode zur fluoreszenz-spektroskopischen bestimmung von biologisch aktiven substanzen.
EP0384130A3 (de)	1991-05-29	Herzinfarkt-Immunoassay
KR880701379A (ko)	1988-07-26	전기 화학 발광 분석법
ATE78098T1 (de)	1992-07-15	Testverfahren mit oberflaechengebundenem fibrinogen und loesliches markiertes fibrinogen.
ATE98376T1 (de)	1993-12-15	Synthetische htlv-iii-peptid-zusammensetzungen und ihre verwendung.
ATE44621T1 (de)	1989-07-15	Proteinkonjugate von penicillosaeure, ihre herstellung und verwendung.
BG97041A (bg)	1993-12-24	Проби на база протеин-нуклеинова киселина и метод за използването им при имуноизследване
EP0247730A3 (de)	1989-04-12	Antikörper, ihre Herstellung sowie Verwendung und dieselben enthaltende Produkte
DE3779706D1 (de)	1992-07-16	Enzymsensor zur bestimmung von glutaminat-konzentration.
DE3850931D1 (de)	1994-09-08	Heterobifunktionelle Kupplungsmittel.
ATE48037T1 (de)	1989-12-15	Verfahren und reagenz zur verwendung zur bestimmung von pivka-ii.
DE3667061D1 (en)	1989-12-28	New protein isolated from blood, process for preparing said protein, antibodies against said new protein, and pharmaceutical compositions containing said protein or said antibodies
DK577089D0 (da)	1989-11-17	Substratsammensaetning til alkalisk phosphatase og assayfremgangsmaade, hvori denne sammensaetning anvendes
DE3473475D1 (en)	1988-09-22	Process for determining substrate or enzymatic activity
ATE191568T1 (de)	2000-04-15	Spezifische bindungssubstanzen für antikörper und deren verwendung für immunoassays oder vakzine
DE3681940D1 (de)	1991-11-21	Reagenz zur bestimmung durch haemagglutination von antikoerpern gegen bakterien-toxine, verfahren zu ihrer herstellung und verwendung.
EP0276984A3 (de)	1989-05-03	Bestimmung von Anti-DNS-Antikörpern
IT8447751A0 (it)	1984-02-24	Composizione contenente polisaccaride per legare proteine specifiche, metodo per ottenerla e procedimento nonche' corredo di saggio che la impiegano
EP0289187A3 (de)	1990-03-28	Vinyl-substituierte Radiohalogen-Konjugate zur Markierung von Proteinen
DE3767659D1 (de)	1991-02-28	Verfahren und testelement zum auffinden von zellaesionen.
ATE66534T1 (de)	1991-09-15	Nortriptylinderivate, verfahren zu ihrer herstellung, deren konjugate mit antigenischen proteinen und enzymen, antikoerper davon und verwandte verfahren zur bestimmung.
EP0248147A3 (de)	1989-02-15	Verfahren zur Bestimmung der Anwesenheit von Krebszellen
ATE96177T1 (de)	1993-11-15	Fibrinspezifischer antikoerper, verfahren zu seiner herstellung und seine verwendung.