ATE446356T1 - Herstellung von glycerolderivaten und zwischenprodukte dafür - Google Patents
Herstellung von glycerolderivaten und zwischenprodukte dafürInfo
- Publication number
- ATE446356T1 ATE446356T1 AT06783328T AT06783328T ATE446356T1 AT E446356 T1 ATE446356 T1 AT E446356T1 AT 06783328 T AT06783328 T AT 06783328T AT 06783328 T AT06783328 T AT 06783328T AT E446356 T1 ATE446356 T1 AT E446356T1
- Authority
- AT
- Austria
- Prior art keywords
- glycerol
- protecting group
- group
- production
- intermediate products
- Prior art date
Links
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical class OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 title abstract 6
- 239000013067 intermediate product Substances 0.000 title 1
- 238000000034 method Methods 0.000 abstract 2
- 125000006239 protecting group Chemical group 0.000 abstract 2
- 238000006640 acetylation reaction Methods 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 238000010511 deprotection reaction Methods 0.000 abstract 1
- 125000005313 fatty acid group Chemical group 0.000 abstract 1
- 150000002314 glycerols Chemical class 0.000 abstract 1
- 125000004665 trialkylsilyl group Chemical group 0.000 abstract 1
- 125000002221 trityl group Chemical group [H]C1=C([H])C([H])=C([H])C([H])=C1C([*])(C1=C(C(=C(C(=C1[H])[H])[H])[H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/48—Preparation of compounds having groups
- C07C41/50—Preparation of compounds having groups by reactions producing groups
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
- C11C3/00—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom
- C11C3/04—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom by esterification of fats or fatty oils
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Wood Science & Technology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020050065792A KR100789323B1 (ko) | 2005-07-20 | 2005-07-20 | 글리세롤 유도체의 위치 선택적 제조방법 및 그 중간체 |
| PCT/KR2006/002809 WO2007011150A1 (en) | 2005-07-20 | 2006-07-18 | Preparation of glycerol derivatives and intermediates therefor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE446356T1 true ATE446356T1 (de) | 2009-11-15 |
Family
ID=37669001
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06783328T ATE446356T1 (de) | 2005-07-20 | 2006-07-18 | Herstellung von glycerolderivaten und zwischenprodukte dafür |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7868196B2 (de) |
| EP (1) | EP1907345B1 (de) |
| JP (1) | JP4717117B2 (de) |
| KR (1) | KR100789323B1 (de) |
| CN (1) | CN101223121B (de) |
| AT (1) | ATE446356T1 (de) |
| CA (1) | CA2615519C (de) |
| DE (1) | DE602006009943D1 (de) |
| ES (1) | ES2335530T3 (de) |
| RU (1) | RU2392264C2 (de) |
| WO (1) | WO2007011150A1 (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5419119B2 (ja) * | 2007-08-20 | 2014-02-19 | 国立大学法人名古屋大学 | エステルの製造法 |
| KR101278874B1 (ko) | 2011-09-23 | 2013-06-26 | 주식회사 엔지켐생명과학 | 1-팔미토일-3-아세틸글리세롤의 제조방법 및 이를 이용한 1-팔미토일-2-리놀레오일-3-아세틸글리세롤의 제조방법 |
| EP3037092B1 (de) * | 2013-08-19 | 2020-01-01 | Enzychem Lifesciences Corporation | Zusammensetzung mit einer monoacetyldiglyceridverbindung als wirkstoff zur hemmung von blutkrebs |
| KR101621856B1 (ko) * | 2013-08-19 | 2016-05-17 | 한국생명공학연구원 | 모노아세틸디아실글리세롤 화합물을 유효성분으로 함유하는 류마티스 관절염의 예방 또는 치료용 조성물 |
| CA2921849C (en) * | 2013-08-19 | 2018-05-08 | Korea Research Institute Of Bioscience And Biotechnology | Composition containing monoacetyldiglyceride compound as active ingredient for preventing or treating chronic obstructive pulmonary disease |
| CN105658213A (zh) | 2013-08-19 | 2016-06-08 | Enzychem生命科学株式会社 | 含有以单乙酰基二酰基甘油化合物作为有效成分的哮喘的预防或者治疗用组合物 |
| KR20150027008A (ko) | 2013-09-03 | 2015-03-11 | 한국생명공학연구원 | 모노아세틸디아실글리세롤 화합물을 유효성분으로 함유하는 아토피 피부염의 예방 또는 치료용 조성물 |
| KR20150032223A (ko) * | 2013-09-17 | 2015-03-25 | 한국생명공학연구원 | 모노아세틸디아실글리세롤 화합물을 유효성분으로 함유하는 적혈구계 세포 분화 또는 증식 촉진용 조성물 |
| CN103787880A (zh) * | 2014-01-21 | 2014-05-14 | 山东省泰和水处理有限公司 | 用乙酰氯合成三醋酸甘油酯的方法 |
| US20150266803A1 (en) * | 2014-03-24 | 2015-09-24 | Enzychem Lifesciences Corporation | Method for preparing monoacetyglycerols and esters thereof |
| JP6321886B2 (ja) | 2014-05-15 | 2018-05-09 | エンジーケム ライフサイエンシーズ コーポレーションＥｎｚｙｃｈｅｍ Ｌｉｆｅｓｃｉｅｎｃｅｓ Ｃｏｒｐｏｒａｔｉｏｎ | 白血球減少症及び血小板減少症に対する治療方法 |
| WO2015192272A1 (zh) * | 2014-06-20 | 2015-12-23 | 中国农业科学院饲料研究所 | 一种三丁酸甘油酯的制备方法 |
| WO2016019313A1 (en) * | 2014-08-01 | 2016-02-04 | Enzychem Lifesciences Corporation | Composition and method for treating restless legs syndrome and leg cramps |
| JP6372887B2 (ja) * | 2015-05-14 | 2018-08-15 | 信越化学工業株式会社 | 有機膜材料、有機膜形成方法、パターン形成方法、及び化合物 |
| US9808438B2 (en) | 2015-11-09 | 2017-11-07 | Enzychem Lifesciences Corporation | Method for treating mucositis |
| KR101817552B1 (ko) | 2016-10-13 | 2018-01-11 | 주식회사 엔지켐생명과학 | 모노아세틸디아실글리세롤 화합물을 함유하는 간염의 예방 또는 치료용 조성물 |
| KR101836822B1 (ko) | 2016-10-17 | 2018-03-09 | 주식회사 엔지켐생명과학 | 모노아세틸디아실글리세롤 화합물을 함유하는 건선의 예방 또는 치료용 조성물 |
| KR102076314B1 (ko) * | 2018-07-16 | 2020-02-11 | (주) 에프엔지리서치 | 녹용에서 분리한 신규 화합물 및 이의 약학적 용도 |
| KR102333606B1 (ko) * | 2019-10-15 | 2021-12-01 | 주식회사 엔지켐생명과학 | 1-팔미토일-2-리놀레오일-3-아세틸 글리세롤의 제조 방법 |
| KR102807284B1 (ko) * | 2023-05-25 | 2025-05-19 | 광동제약 주식회사 | 1-팔미토일-2-리놀레오일-3-아세틸-rac-글리세롤의 효소적 제조방법 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3558656A (en) * | 1968-04-19 | 1971-01-26 | Smith Kline French Lab | Glycerol trichloroethyl carbonate and derivatives |
| JPS6263593A (ja) | 1985-09-13 | 1987-03-20 | Fumimori Satou | グリセロ−ル誘導体の製造法 |
| JP2556849B2 (ja) * | 1986-02-13 | 1996-11-27 | 三共株式会社 | グリセリン誘導体 |
| US4925649A (en) * | 1987-06-12 | 1990-05-15 | The University Of Michigan | Radioiodinated diacylglycerol analogues and methods of use |
| ATE181210T1 (de) * | 1990-12-07 | 1999-07-15 | Nabisco Inc | Kalorienarme triglyzerid mischungen |
| JPH05271256A (ja) * | 1991-03-13 | 1993-10-19 | Mitsui Toatsu Chem Inc | 脂質類化合物およびその製造方法 |
| US5137660A (en) * | 1991-03-15 | 1992-08-11 | The Procter & Gamble Company | Regioselective synthesis of 1,3-disubstituted glycerides |
| KR100283601B1 (ko) * | 1993-02-19 | 2001-03-02 | 아만 히데아키 | 글리세롤 유도체, 디바이스 및 의약 조성물 |
| US5827836A (en) * | 1996-11-15 | 1998-10-27 | Clarion Pharmaceuticals Inc. | Retinoid glycerol phospholipid conjugates |
| EP0906759A1 (de) * | 1997-10-02 | 1999-04-07 | Roche Diagnostics GmbH | Neue Osteoblastenspezifische Mitogene: Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
| KR100283010B1 (ko) | 1997-11-20 | 2001-04-02 | 전길자 | 녹용 추출물을 함유하는 조혈모세포 및 혈소판 전구세포 증식촉진용 조성물 |
| KR100291743B1 (ko) | 1997-11-20 | 2001-05-15 | 전길자 | 글리세롤 유도체의 제조방법 |
| WO1999026640A1 (en) * | 1997-11-20 | 1999-06-03 | Bukwang Pharm. Ind. Co., Ltd. | Pharmaceutical composition containing extracts of cervus nippon antlers having growth-stimulating activities of hematopoietic stem cells and megakaryocytes |
| CA2562897C (en) * | 2004-04-24 | 2011-03-15 | Sang-Hee Kim | Immunomodulating agent, anti-cancer agent and health food containing monoacetyldiacylglycerol derivatives |
-
2005
- 2005-07-20 KR KR1020050065792A patent/KR100789323B1/ko not_active Expired - Fee Related
-
2006
- 2006-07-18 DE DE602006009943T patent/DE602006009943D1/de active Active
- 2006-07-18 ES ES06783328T patent/ES2335530T3/es active Active
- 2006-07-18 WO PCT/KR2006/002809 patent/WO2007011150A1/en not_active Ceased
- 2006-07-18 CN CN2006800261556A patent/CN101223121B/zh active Active
- 2006-07-18 RU RU2008106478/04A patent/RU2392264C2/ru active
- 2006-07-18 US US11/989,074 patent/US7868196B2/en active Active
- 2006-07-18 EP EP06783328A patent/EP1907345B1/de active Active
- 2006-07-18 AT AT06783328T patent/ATE446356T1/de not_active IP Right Cessation
- 2006-07-18 CA CA2615519A patent/CA2615519C/en active Active
- 2006-07-18 JP JP2008522697A patent/JP4717117B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP4717117B2 (ja) | 2011-07-06 |
| JP2009501788A (ja) | 2009-01-22 |
| EP1907345B1 (de) | 2009-10-21 |
| RU2392264C2 (ru) | 2010-06-20 |
| WO2007011150A1 (en) | 2007-01-25 |
| DE602006009943D1 (de) | 2009-12-03 |
| US7868196B2 (en) | 2011-01-11 |
| ES2335530T3 (es) | 2010-03-29 |
| US20090253923A1 (en) | 2009-10-08 |
| KR20070010841A (ko) | 2007-01-24 |
| CN101223121B (zh) | 2011-05-25 |
| KR100789323B1 (ko) | 2007-12-28 |
| CA2615519C (en) | 2011-03-15 |
| RU2008106478A (ru) | 2009-08-27 |
| EP1907345A1 (de) | 2008-04-09 |
| CA2615519A1 (en) | 2007-01-25 |
| EP1907345A4 (de) | 2008-12-10 |
| CN101223121A (zh) | 2008-07-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE446356T1 (de) | Herstellung von glycerolderivaten und zwischenprodukte dafür | |
| NZ599437A (en) | Enzymatic process for obtaining 17 alpha-monoesters of cortexolone and/or its 9,11-dehydroderivatives. | |
| BR0309659A (pt) | Método para produzir vìrus de uma cultura de células, composição, e, método para produzir reovìrus infeccioso | |
| CN105330643A (zh) | 卡比替尼的制备方法 | |
| KR102644587B1 (ko) | 유사 세라마이드 화합물 및 그 제조방법 | |
| ATE373681T1 (de) | Ester von hyaluronsäure mit rhein, herstellungsverfahren dafür und zusammensetzungen damit | |
| EE04642B1 (et) | (1H)benso[c]kinolisiin-3-ooni derivaatide sünteesi meetod | |
| WO2008093700A1 (ja) | トレハロース化合物、その製造方法、及び該化合物を含有する免疫賦活剤 | |
| CN102993256B (zh) | 一种选择性脱除全三甲基硅基保护糖的伯位三甲基硅基的方法 | |
| CN114478664A (zh) | 一种反式阿魏酸-4-葡萄糖苷的化学合成方法 | |
| CN102718818B (zh) | 含氮曲克芦丁衍生物及其制备方法和用途 | |
| CN103304623B (zh) | 一种6β,19-环氧雄甾-3,17-二酮的合成方法 | |
| WO2005063731A3 (en) | Production of dihydronepetalactone by reduction of nepetalic acid | |
| CN108715875B (zh) | 酶化学法合成结构明确的硫酸肝素寡糖的方法 | |
| Dupouy et al. | Synthesis of spiro ɛ, ζ-D-CNA in xylo configuration featuring noncanonical δ/ɛ/ζ torsion angle combination | |
| JP2002502613A5 (de) | ||
| Sriharsha et al. | Synthesis and antimicrobial activity of novel 1, 3-oxazolidine nucleoside analogues | |
| DE60108112D1 (de) | Verfahren zur herstellung von carbostyril-derivaten | |
| DE60314904D1 (de) | Verfahren zur herstellung von chinoloncarboxylat-derivaten | |
| CN102242068B (zh) | 催化阿糖胞苷酯合成反应的霉菌细胞催化剂的制备方法 | |
| CN105017189B (zh) | 一种稠合环酮类化合物的合成方法 | |
| Shen et al. | An Efficient Semi‐Synthetic Method to Construct Docetaxel via Sterically Crowded Linear Side Chain Esterification | |
| NO20071996L (no) | Framgangsmate for esterifisering av karbothiotisk syre | |
| CN114621985B (zh) | 一种生物催化合成紫杉醇侧链的方法 | |
| CN104292201A (zh) | 3-酯基儿茶素的制备方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |