ATE446678T1 - Zusammensetzungen von zu schnellem wachstum fähigen, restriktierten zellen, die proliferation unterdrückende materialien produzieren und ihre verwendung - Google Patents

Zusammensetzungen von zu schnellem wachstum fähigen, restriktierten zellen, die proliferation unterdrückende materialien produzieren und ihre verwendung

Info

Publication number
ATE446678T1
ATE446678T1 AT99971668T AT99971668T ATE446678T1 AT E446678 T1 ATE446678 T1 AT E446678T1 AT 99971668 T AT99971668 T AT 99971668T AT 99971668 T AT99971668 T AT 99971668T AT E446678 T1 ATE446678 T1 AT E446678T1
Authority
AT
Austria
Prior art keywords
compositions
growing
rapid
restricted cells
suppressing materials
Prior art date
Application number
AT99971668T
Other languages
English (en)
Inventor
Shirin Asina
Kanti Jain
Albert Rubin
Barry Smith
Kurt Stenzel
Original Assignee
Rogosin Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rogosin Inst filed Critical Rogosin Inst
Application granted granted Critical
Publication of ATE446678T1 publication Critical patent/ATE446678T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/13Tumour cells, irrespective of tissue of origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/04Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0693Tumour cells; Cancer cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Oncology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
AT99971668T 1998-11-09 1999-11-09 Zusammensetzungen von zu schnellem wachstum fähigen, restriktierten zellen, die proliferation unterdrückende materialien produzieren und ihre verwendung ATE446678T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/188,476 US6224912B1 (en) 1996-04-03 1998-11-09 Cancer-cell proliferation-suppressing material produced by cancer cells restricted by entrapment
PCT/US1999/026413 WO2000027207A1 (en) 1998-11-09 1999-11-09 Compositions of restricted cells capable of rapid growth which produce proliferation suppressive materials, and uses thereof

Publications (1)

Publication Number Publication Date
ATE446678T1 true ATE446678T1 (de) 2009-11-15

Family

ID=22693322

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99971668T ATE446678T1 (de) 1998-11-09 1999-11-09 Zusammensetzungen von zu schnellem wachstum fähigen, restriktierten zellen, die proliferation unterdrückende materialien produzieren und ihre verwendung

Country Status (19)

Country Link
US (4) US6224912B1 (de)
EP (1) EP1128731B1 (de)
JP (2) JP4294223B2 (de)
KR (3) KR20020013465A (de)
CN (1) CN1325271A (de)
AT (1) ATE446678T1 (de)
AU (1) AU769411B2 (de)
CA (1) CA2334483C (de)
DE (1) DE69941599D1 (de)
DK (1) DK1128731T3 (de)
EG (1) EG24212A (de)
ES (1) ES2335723T3 (de)
HK (1) HK1039439A1 (de)
IL (3) IL139704A0 (de)
NO (2) NO20012152L (de)
NZ (1) NZ511220A (de)
PT (1) PT1128731E (de)
RU (2) RU2268735C1 (de)
WO (1) WO2000027207A1 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1666585T3 (da) * 1994-01-13 2009-01-12 Rogosin Inst Makroindkapslede sekretoriske celler
USRE39542E1 (en) * 1994-01-13 2007-04-03 The Rogosin Institute Preparation of agarose coated, solid agarose-collagen beads containing secretory cells
US7297331B2 (en) * 1996-04-03 2007-11-20 The Rogosin Institute Beads containing restricted cancer cells producing material suppressing cancer cell proliferation
US6224912B1 (en) * 1996-04-03 2001-05-01 The Rogo Institute Cancer-cell proliferation-suppressing material produced by cancer cells restricted by entrapment
US20050053586A1 (en) 2003-09-04 2005-03-10 Bryan Conn Entrapped stem cells and uses thereof
WO2006053052A2 (en) * 2004-11-11 2006-05-18 The Rogosin Institute Method for treating patients with implants of islets which have been kept in long term, in vitro culture
RU2417090C2 (ru) * 2005-09-26 2011-04-27 Дзе Рогозин Инститьют, Инк. Макрогранулы агарозы seakem gold, содержащие секреторные клетки, и их применение
JP4891841B2 (ja) 2007-06-08 2012-03-07 浜松ホトニクス株式会社 分光モジュール
WO2008149940A1 (ja) 2007-06-08 2008-12-11 Hamamatsu Photonics K.K. 分光モジュール
JP4887221B2 (ja) 2007-06-08 2012-02-29 浜松ホトニクス株式会社 分光モジュール
EP2063238B1 (de) 2007-06-08 2018-08-22 Hamamatsu Photonics K.K. Spektroskop
JP4891840B2 (ja) 2007-06-08 2012-03-07 浜松ホトニクス株式会社 分光モジュール
US8049887B2 (en) 2007-06-08 2011-11-01 Hamamatsu Photonics K.K. Spectroscopic module
US8068223B2 (en) 2007-06-08 2011-11-29 Hamamatsu Photonics K.K. Spectroscopic module
CA2698212A1 (en) 2007-08-23 2009-02-26 Intrexon Corporation Methods and compositions for diagnosing disease
MX2010003371A (es) 2007-09-28 2010-05-05 Intrexon Corp Constructos interruptores genicos terapeuticos y biorreactores para la expresion de moleculas bioterapeuticas y usos de los mismos.
CN102628711B (zh) 2008-03-04 2016-01-20 浜松光子学株式会社 分光模块
JP5205238B2 (ja) 2008-05-15 2013-06-05 浜松ホトニクス株式会社 分光モジュール
JP5207938B2 (ja) 2008-05-15 2013-06-12 浜松ホトニクス株式会社 分光モジュール及び分光モジュールの製造方法
JP2009300418A (ja) 2008-05-15 2009-12-24 Hamamatsu Photonics Kk 分光モジュール
JP5205241B2 (ja) 2008-05-15 2013-06-05 浜松ホトニクス株式会社 分光モジュール
JP5415060B2 (ja) 2008-05-15 2014-02-12 浜松ホトニクス株式会社 分光モジュール
JP5512961B2 (ja) 2008-05-15 2014-06-04 浜松ホトニクス株式会社 分光モジュール及びその製造方法
JP5205240B2 (ja) 2008-05-15 2013-06-05 浜松ホトニクス株式会社 分光モジュールの製造方法及び分光モジュール
EP2412800A1 (de) * 2010-07-29 2012-02-01 Koninklijke Nederlandse Akademie van Wetenschappen Leberorganoid, Verwendungen davon und Kultivierungsverfahren zum Erhalten davon
US8572921B2 (en) * 2009-03-27 2013-11-05 Davinci Roofscapes, Llc One piece hip and ridge shingle
EP3228629A1 (de) * 2010-06-16 2017-10-11 Minerva Biotechnologies Corporation Neuprogrammierung von krebszellen
KR20190027969A (ko) * 2010-08-12 2019-03-15 얀센 바이오테크 인코포레이티드 췌장 내분비 전구 세포를 이용한 당뇨병의 치료
JP5899230B2 (ja) * 2010-11-23 2016-04-06 ザ・ロゴシン・インスティテュート・インコーポレイテッド 潜在的治療薬をスクリーニングするため、幹細胞様特性を有する癌細胞を単離するため、アガロース内にカプセル化されアガロースでコーティングされた癌細胞を使用する方法、及び本方法により得られる細胞
NZ624195A (en) 2012-01-31 2015-07-31 Rogosin Inst Improved method for manufacture of macrobeads
US10697972B2 (en) 2016-01-12 2020-06-30 Bioatla, Llc Diagnostics using conditionally active antibodies
EP3403098B1 (de) 2016-01-12 2021-09-22 BioAtla, Inc. Diagnostika mit bedingt aktiven antikörpern
KR200485213Y1 (ko) 2016-11-02 2017-12-07 고수한 높이 조절이 가능한 조립식평상
US12038432B2 (en) 2018-02-02 2024-07-16 Wake Forest University Health Sciences Organoids related to immunotherapy and methods of preparing and using the same

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3865689A (en) 1972-11-09 1975-02-11 Hoffmann La Roche Method of producing carcinoembryonic antigens
US4285930A (en) 1977-12-08 1981-08-25 Likhite Vilas V Antigens comprising immunostimulant adjuvants and their use in immunotherapy
US4352883A (en) 1979-03-28 1982-10-05 Damon Corporation Encapsulation of biological material
US4409331A (en) 1979-03-28 1983-10-11 Damon Corporation Preparation of substances with encapsulated cells
US4391909A (en) 1979-03-28 1983-07-05 Damon Corporation Microcapsules containing viable tissue cells
DE3032931C2 (de) 1980-09-02 1982-07-29 Robert Bürkle GmbH & Co, 7290 Freudenstadt Verfahren und Anordnung zur Herstellung von Mehrschicht-Leiterplatten
SE441009B (sv) 1982-03-08 1985-09-02 Kjell Nilsson Sett att immobilisera levande biomaterial i perlformiga polymerer
US4798786A (en) 1982-05-06 1989-01-17 Stolle Research And Development Corporation Living cells encapsulated in crosslinked protein
JPS5933223A (ja) 1982-08-20 1984-02-23 Koken Kk 人の悪性腫瘍細胞増殖抑制剤
CA1196862A (en) 1983-06-01 1985-11-19 Connaught Laboratories Limited Microencapsulation of living tissue and cells
US4663286A (en) 1984-02-13 1987-05-05 Damon Biotech, Inc. Encapsulation of materials
US4680174A (en) 1984-05-24 1987-07-14 Damon Biotech, Inc. Induction of immune response by immunization with encapsulated antigen-producing cells
JPS6118721A (ja) 1984-07-06 1986-01-27 Kyowa Hakko Kogyo Co Ltd 新規抗腫瘍性物質
US4997443A (en) 1985-08-26 1991-03-05 Hana Biologics, Inc. Transplantable artificial tissue and process
US4902295A (en) 1985-08-26 1990-02-20 Hana Biologics, Inc. Transplantable artificial tissue
US5618715A (en) 1985-12-20 1997-04-08 Oncogen Limited Partnership Oncostatin M and novel compositions having anti-neoplastic activity
SE8604684L (sv) 1986-11-03 1988-05-04 Excorim Kommanditbolag Sett att belegga fasta partiklar med en hydrofil gel samt genom settet belagda partiklar
JPS6463395A (en) 1987-05-04 1989-03-09 Oncogen Oncostatin m and novel composition having antitumor activity
JPH0216994A (ja) 1988-07-05 1990-01-19 Nippon Mining Co Ltd 細胞増殖阻害因子及びその製造方法
US5053332A (en) 1989-07-24 1991-10-01 Cook Richard B Agarose beads, preferably incorporating biological materials
US5227298A (en) 1990-08-17 1993-07-13 The Trustees Of Columbia University In The City Of New York Method for microencapuslation of cells or tissue
US5800829A (en) 1991-04-25 1998-09-01 Brown University Research Foundation Methods for coextruding immunoisolatory implantable vehicles with a biocompatible jacket and a biocompatible matrix core
ATE156344T1 (de) 1991-04-25 1997-08-15 Univ Brown Res Found Implantierbare, biokompatible immunisolator- trägersubstanz zum abgeben ausgesuchter, therapeutischer produkte
NZ250363A (en) * 1992-12-04 1996-11-26 Susanna Elizabeth Chalmers A topical dressing containing a dessicant and an antimicrobial or antiseptic agent
SG48813A1 (en) 1993-08-12 1998-05-18 Cytotherapeutics Inc Improved composition and methods for the delivery of biologically active molecules using genetically altered cells contained in biocompatible immunoisolatory capsules
DK1666585T3 (da) * 1994-01-13 2009-01-12 Rogosin Inst Makroindkapslede sekretoriske celler
WO1996001611A1 (en) 1994-07-08 1996-01-25 Baxter International Inc. Implanted device containing tumor cells for the treatment of cancer
US6224912B1 (en) * 1996-04-03 2001-05-01 The Rogo Institute Cancer-cell proliferation-suppressing material produced by cancer cells restricted by entrapment
ATE374034T1 (de) 1996-04-03 2007-10-15 Rogosin Inst Konditioniertes medium und diffusionsfähiges biologisches material gewonnen durch inkubierung von eingeschlossenen zellen
US5888497A (en) * 1996-04-03 1999-03-30 The Rogosin Institute Agarose coated agarose beads containing cancer cells that produce material which suppresses cancer cell proliferation

Also Published As

Publication number Publication date
JP2005343899A (ja) 2005-12-15
CA2334483C (en) 2012-01-10
CA2334483A1 (en) 2000-05-18
CN1325271A (zh) 2001-12-05
JP2002529060A (ja) 2002-09-10
US20030143281A1 (en) 2003-07-31
IL139704A0 (en) 2002-02-10
US6818230B2 (en) 2004-11-16
AU769411B2 (en) 2004-01-29
DE69941599D1 (de) 2009-12-10
KR20050055797A (ko) 2005-06-13
RU2268735C1 (ru) 2006-01-27
JP4294223B2 (ja) 2009-07-08
US7041504B2 (en) 2006-05-09
IL177967A0 (en) 2006-12-31
ES2335723T3 (es) 2010-03-31
RU2236855C2 (ru) 2004-09-27
EP1128731A1 (de) 2001-09-05
WO2000027207A8 (en) 2000-09-21
DK1128731T3 (da) 2010-01-25
NO20012152L (no) 2001-07-05
US20030143739A1 (en) 2003-07-31
US6224912B1 (en) 2001-05-01
EG24212A (en) 2008-10-28
EP1128731A4 (de) 2003-06-04
NZ511220A (en) 2003-12-19
NO20101615L (no) 2001-07-05
WO2000027207A1 (en) 2000-05-18
AU1472600A (en) 2000-05-29
KR20020013465A (ko) 2002-02-20
RU2004115040A (ru) 2005-10-27
IL139704A (en) 2006-12-31
HK1039439A1 (zh) 2002-04-26
PT1128731E (pt) 2010-02-02
KR20040075922A (ko) 2004-08-30
IL177967A (en) 2010-12-30
US20020168415A1 (en) 2002-11-14
US6808705B2 (en) 2004-10-26
NO20012152D0 (no) 2001-05-02
EP1128731B1 (de) 2009-10-28

Similar Documents

Publication Publication Date Title
ATE446678T1 (de) Zusammensetzungen von zu schnellem wachstum fähigen, restriktierten zellen, die proliferation unterdrückende materialien produzieren und ihre verwendung
ATE317595T1 (de) Uberprüfung der beschichtungskante
DE60138308D1 (de) Herstellung von feinkörnigen teilchen
CA2291222A1 (en) Naphthyridinones for inhibiting protein tyrosine kinase and cell cycle kinase mediated cellular proliferation
TWI263235B (en) Material for electrolytic solutions and use thereof
TR200102800T2 (tr) Yeni bileşikler.
WO1998007830A3 (en) COMPLETE GENOME SEQUENCE OF THE METHANOGENIC ARCHAEON, $i(METHANOCOCCUS JANNASCHII)
AU7709198A (en) Low background multi-well plates for fluorescence measurements of biological andbiochemical samples
WO2001083547A3 (en) Anti-inflammatory compounds and uses thereof
ATE255632T1 (de) Immortalisierung bzw. desimmortalisierung von zellen
SE9900079L (sv) Sätt att tillverka hårdmetall med en bimodal kornstorleksfördelning och som innehåller korntillväxthämmare
DE69942063D1 (de) Antagonisten von 'hedgehog' und 'patched' zur inhibierung des wachstums und der differenzierung von zellen und geweben, als auch deren verwendungen
DK0726754T3 (da) Bandager
DE60008798D1 (de) Extrakt von undifferenzierten zellen einer pflanze der gattung leontopodium und ihn enthaltende zusammensetzungen
AU5892399A (en) 1, 2, 4-triazole-3-thione compounds
GB0226316D0 (en) Novel compounds for modulating cell proliferation
WO2000000599A3 (en) Composition for the induction of apoptosis in target cells
IL158147A0 (en) Methods and cells for identifying cancer-related genes
ATE267195T1 (de) Oxiranyl-triazolinthione und ihre verwendung als mikrobizide
ATE452166T1 (de) Beschichtungsstoffe und ihre verwendung zur herstellung schweissbarer beschichtungen
DE69906327D1 (de) In c6-c7 annelierte naphtopyrane, ihre herstellung und zusammensetzungen und sie enthaltende (co)polymermatrizen
DE69901835D1 (de) Wärmehärtbare harzartige bindemittelzusammensetzungen, deren herstellung und deren verwendung als beschichtungen
TR199800152T1 (xx) Endotelin Resept�r Antagonistleri
TR200003695T2 (tr) Anjiyostatin bağlayıcı protein.
DE69917643D1 (de) Alpha-(2-hydroxyphenyl)nitrone, diese enthaltenden pharmazeutische zubereitungen sowie deren verwendung zur behandlung von entzündungen

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1128731

Country of ref document: EP