ATE448228T1 - Pyrrolopyrimidinderivate zur behandlung proliferativer krankheiten - Google Patents

Pyrrolopyrimidinderivate zur behandlung proliferativer krankheiten

Info

Publication number
ATE448228T1
ATE448228T1 AT05707074T AT05707074T ATE448228T1 AT E448228 T1 ATE448228 T1 AT E448228T1 AT 05707074 T AT05707074 T AT 05707074T AT 05707074 T AT05707074 T AT 05707074T AT E448228 T1 ATE448228 T1 AT E448228T1
Authority
AT
Austria
Prior art keywords
pyrrolopyrimide
derivatives
treatment
proliferative diseases
proliferative
Prior art date
Application number
AT05707074T
Other languages
English (en)
Inventor
Giorgio Caravatti
Peter Traxler
Thomas Esser
Handan He
Original Assignee
Novartis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Pharma Gmbh filed Critical Novartis Pharma Gmbh
Application granted granted Critical
Publication of ATE448228T1 publication Critical patent/ATE448228T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT05707074T 2004-01-29 2005-01-28 Pyrrolopyrimidinderivate zur behandlung proliferativer krankheiten ATE448228T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54003404P 2004-01-29 2004-01-29
PCT/EP2005/000876 WO2005075460A2 (en) 2004-01-29 2005-01-28 Pyrrolopyrimidine derivatives for treating proliferative diseases

Publications (1)

Publication Number Publication Date
ATE448228T1 true ATE448228T1 (de) 2009-11-15

Family

ID=34837369

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05707074T ATE448228T1 (de) 2004-01-29 2005-01-28 Pyrrolopyrimidinderivate zur behandlung proliferativer krankheiten

Country Status (19)

Country Link
US (1) US20090247548A1 (de)
EP (1) EP1742937B1 (de)
JP (2) JP4970052B2 (de)
KR (2) KR20060127947A (de)
CN (1) CN101103031B (de)
AR (1) AR047470A1 (de)
AT (1) ATE448228T1 (de)
AU (1) AU2005211493B8 (de)
BR (1) BRPI0507289A (de)
CA (1) CA2553243C (de)
DE (1) DE602005017605D1 (de)
ES (1) ES2332730T3 (de)
MX (1) MXPA06008571A (de)
PE (1) PE20051092A1 (de)
PL (1) PL1742937T3 (de)
PT (1) PT1742937E (de)
RU (1) RU2367662C2 (de)
TW (1) TW200530245A (de)
WO (1) WO2005075460A2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20051092A1 (es) * 2004-01-29 2006-01-20 Novartis Ag Derivados de pirrolo-pirimidina utiles para el tratamiento de enfermedades proliferativas
GB0403606D0 (en) * 2004-02-18 2004-03-24 Novartis Ag Organic compounds
JP2008543975A (ja) * 2006-08-14 2008-12-04 シコール インコーポレイティド 高度に純粋なペメトレキセド二酸およびその調製方法
WO2009115084A2 (de) * 2008-03-20 2009-09-24 Schebo Biotech Ag Neue pyrrolopyrimidin-derivate und deren verwendungen
WO2013008095A1 (en) * 2011-07-08 2013-01-17 Novartis Ag Novel pyrrolo pyrimidine derivatives
KR102686957B1 (ko) * 2016-11-08 2024-07-22 주식회사 대웅제약 신규한 피롤로피리미딘 유도체 및 이를 포함하는 약학적 조성물

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0119249D0 (en) * 2001-08-07 2001-10-03 Novartis Ag Organic compounds
WO2003037897A2 (en) * 2001-10-29 2003-05-08 Novartis Ag Use of 7h-pyrrolo[2,3-d]pyrimidine derivatives in the treatment of solid tumor diseases
PE20051092A1 (es) * 2004-01-29 2006-01-20 Novartis Ag Derivados de pirrolo-pirimidina utiles para el tratamiento de enfermedades proliferativas

Also Published As

Publication number Publication date
EP1742937B1 (de) 2009-11-11
PL1742937T3 (pl) 2010-04-30
RU2006130865A (ru) 2008-03-10
PE20051092A1 (es) 2006-01-20
MXPA06008571A (es) 2006-08-28
KR20060127947A (ko) 2006-12-13
CA2553243C (en) 2013-05-28
CN101103031B (zh) 2011-01-19
BRPI0507289A (pt) 2007-07-03
WO2005075460A2 (en) 2005-08-18
KR20120103733A (ko) 2012-09-19
AU2005211493B8 (en) 2008-09-04
TW200530245A (en) 2005-09-16
AR047470A1 (es) 2006-01-18
PT1742937E (pt) 2009-12-31
AU2005211493A1 (en) 2005-08-18
US20090247548A1 (en) 2009-10-01
EP1742937A2 (de) 2007-01-17
RU2367662C2 (ru) 2009-09-20
ES2332730T3 (es) 2010-02-11
JP2007531710A (ja) 2007-11-08
JP4970052B2 (ja) 2012-07-04
JP2012131795A (ja) 2012-07-12
DE602005017605D1 (de) 2009-12-24
CN101103031A (zh) 2008-01-09
CA2553243A1 (en) 2005-08-18
AU2005211493B2 (en) 2008-08-07
WO2005075460A3 (en) 2007-04-12

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