ATE448479T1 - Analyse von biologischen und/oder chemischen gemischen unter verwendung von magnetischen teilchen - Google Patents
Analyse von biologischen und/oder chemischen gemischen unter verwendung von magnetischen teilchenInfo
- Publication number
- ATE448479T1 ATE448479T1 AT01922159T AT01922159T ATE448479T1 AT E448479 T1 ATE448479 T1 AT E448479T1 AT 01922159 T AT01922159 T AT 01922159T AT 01922159 T AT01922159 T AT 01922159T AT E448479 T1 ATE448479 T1 AT E448479T1
- Authority
- AT
- Austria
- Prior art keywords
- analysis
- frequency
- magnetic particles
- magnetic
- signal
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 239000006249 magnetic particle Substances 0.000 title abstract 3
- 239000000126 substance Substances 0.000 title abstract 2
- 239000012491 analyte Substances 0.000 abstract 1
- 230000006698 induction Effects 0.000 abstract 1
- 238000005259 measurement Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000000523 sample Substances 0.000 abstract 1
- 230000035945 sensitivity Effects 0.000 abstract 1
- 238000001228 spectrum Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/72—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables
- G01N27/74—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
- G01N27/745—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids for detecting magnetic beads used in biochemical assays
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
- G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/12—Measuring magnetic properties of articles or specimens of solids or fluids
- G01R33/1269—Measuring magnetic properties of articles or specimens of solids or fluids of molecules labeled with magnetic beads
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Electrochemistry (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2000105511/28A RU2166751C1 (ru) | 2000-03-09 | 2000-03-09 | Способ анализа смеси биологических и/или химических компонентов с использованием магнитных частиц и устройство для его осуществления |
| PCT/RU2001/000100 WO2001067062A2 (fr) | 2000-03-09 | 2001-03-07 | Procede d'analyse d'un melange de composants biologiques et/ou chimiques utilisant des particules magnetiques et dispositif correspondant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE448479T1 true ATE448479T1 (de) | 2009-11-15 |
Family
ID=20231490
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01922159T ATE448479T1 (de) | 2000-03-09 | 2001-03-07 | Analyse von biologischen und/oder chemischen gemischen unter verwendung von magnetischen teilchen |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US7785902B2 (de) |
| EP (2) | EP2120041B1 (de) |
| JP (1) | JP4817581B2 (de) |
| AT (1) | ATE448479T1 (de) |
| AU (1) | AU2001248937A1 (de) |
| DE (1) | DE60140431D1 (de) |
| ES (2) | ES2333517T3 (de) |
| RU (1) | RU2166751C1 (de) |
| WO (1) | WO2001067062A2 (de) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI113297B (fi) * | 2001-06-19 | 2004-03-31 | Magnasense Oy | Menetelmä ja laitteisto analyyttien kvalitatiiviseksi ja kvantitatiiviseksi osoittamiseksi |
| WO2003102546A2 (en) * | 2002-05-31 | 2003-12-11 | The Regents Of The University Of California | Method and apparatus for detecting substances of interest |
| DE10309132A1 (de) * | 2003-02-28 | 2004-11-18 | Forschungszentrum Jülich GmbH | Verfahren und Vorrichtung zum selektiven Nachweis magnetischer Partikel |
| JP4078247B2 (ja) | 2003-05-02 | 2008-04-23 | キヤノン株式会社 | 磁性体−生体物質複合体型構造体、磁性体に対して結合能を有するアミノ酸配列を有するペプチド断片及びその遺伝子、ならびに磁性体−生体物質複合体型構造体の製造方法 |
| US7038468B2 (en) * | 2003-06-11 | 2006-05-02 | Jan Verspecht | Method and a test setup for measuring large-signal S-parameters that include the coefficients relating to the conjugate of the incident waves |
| RU2366689C2 (ru) | 2003-12-12 | 2009-09-10 | Коултэк Корпорейшн | Методология сухого обогащения перед сжиганием и системы для улучшения характеристик твердого топлива |
| US20060020371A1 (en) * | 2004-04-13 | 2006-01-26 | President And Fellows Of Harvard College | Methods and apparatus for manipulation and/or detection of biological samples and other objects |
| JP2005315744A (ja) * | 2004-04-28 | 2005-11-10 | Canon Inc | 検出素子、検出装置、および素子と試薬を含む検出用キット |
| JP4669259B2 (ja) * | 2004-10-15 | 2011-04-13 | 旭化成株式会社 | 被検物質分析装置及び定量方法 |
| JP4728012B2 (ja) * | 2005-02-28 | 2011-07-20 | 旭化成株式会社 | バイオセンサ |
| JPWO2007034842A1 (ja) * | 2005-09-20 | 2009-03-26 | 国立大学法人北陸先端科学技術大学院大学 | Nmr検出セル、nmr測定方法及びnmr測定用装置 |
| WO2007042959A2 (en) * | 2005-10-12 | 2007-04-19 | Koninklijke Philips Electronics N.V. | Magnetic sensor device with different internal operating frequencies |
| WO2007046051A2 (en) * | 2005-10-19 | 2007-04-26 | Koninklijke Philips Electronics N.V. | Magnetoresistive nanoparticle sensor |
| US8193804B2 (en) * | 2005-11-16 | 2012-06-05 | Rex Chin-Yih Hong | Device for measuring AC magnetization of materials |
| GB0523631D0 (en) * | 2005-11-21 | 2005-12-28 | Univ Cambridge Tech | Magnetic tagging techniques |
| WO2007105141A2 (en) * | 2006-03-15 | 2007-09-20 | Koninklijke Philips Electronics N. V. | Magnetic sensor device with gain stabilization |
| EP1999452A2 (de) * | 2006-03-15 | 2008-12-10 | Koninklijke Philips Electronics N.V. | Sensorvorrichtung mit abwechselnden reizfeldern |
| ES2535544T3 (es) * | 2006-03-21 | 2015-05-12 | Magnisense Se | Procedimiento y dispositivo de prueba inmunocromatográfica magnética |
| US8585788B2 (en) | 2006-03-31 | 2013-11-19 | Coaltek, Inc. | Methods and systems for processing solid fuel |
| CA2647698C (en) * | 2006-03-31 | 2015-08-11 | Coaltek Inc. | Methods and systems for enhancing solid fuel properties |
| US8585786B2 (en) | 2006-03-31 | 2013-11-19 | Coaltek, Inc. | Methods and systems for briquetting solid fuel |
| JP2007278748A (ja) * | 2006-04-04 | 2007-10-25 | Canon Inc | 標的物質検出素子、検出材料、及び検出キット |
| US10488408B2 (en) | 2006-05-09 | 2019-11-26 | Koninklijke Philips N.V. | Detection of target molecules in a sample by using a magnetic field |
| EP2074421B1 (de) * | 2006-10-12 | 2014-12-17 | Koninklijke Philips N.V. | Schneller biosensor mit reagenzschicht |
| EP2078199B1 (de) * | 2006-10-12 | 2013-03-06 | Koninklijke Philips Electronics N.V. | Nachweissystem und verfahren mit hilfe eines magnetischen und/oder elektrischen etiketts |
| CN101558313A (zh) * | 2006-12-12 | 2009-10-14 | 皇家飞利浦电子股份有限公司 | 通过机械地移动至少一个磁体来将磁力应用到生物传感器表面的系统 |
| FR2914060B1 (fr) | 2007-03-23 | 2009-06-12 | Magnisense Technology Ltd | Dispositif et procede de mesure de la masse de materiau magnetique, appareil d'analyse incorporant ce dispositif |
| JP5201885B2 (ja) * | 2007-06-19 | 2013-06-05 | キヤノン株式会社 | 磁性物質の検出装置及び検出方法 |
| JP5207668B2 (ja) * | 2007-06-22 | 2013-06-12 | キヤノン株式会社 | 検出装置及び検出方法 |
| JP5349840B2 (ja) * | 2007-06-25 | 2013-11-20 | キヤノン株式会社 | 磁気センサ素子及びそれを備える検出装置 |
| FR2920875B1 (fr) | 2007-09-07 | 2009-12-04 | Magnisense Tech Limited | Procede et dispositif d'analyse de materiau magnetique, appareil incluant le dispositif |
| WO2009083814A2 (en) * | 2007-12-20 | 2009-07-09 | Koninklijke Philips Electronics N.V. | Microelectronic sensor device for the detection of target particles |
| US9176206B2 (en) * | 2008-03-07 | 2015-11-03 | California Institute Of Technology | Effective-inductance-change based magnetic particle sensing |
| EP2108938A1 (de) * | 2008-04-09 | 2009-10-14 | Koninklijke Philips Electronics N.V. | Träger für optische Detektion bei kleinen Probenvolumen |
| RU2491540C2 (ru) * | 2009-01-22 | 2013-08-27 | Конинклейке Филипс Электроникс Н.В. | Протокол смешанного возбуждения для устройства магнитного биодатчика |
| US9599591B2 (en) | 2009-03-06 | 2017-03-21 | California Institute Of Technology | Low cost, portable sensor for molecular assays |
| FI124980B (fi) * | 2010-01-20 | 2015-04-15 | Hemeltron | Ferromagneettisten hiukkasten mittausjärjestelmä |
| JP2012049434A (ja) * | 2010-08-30 | 2012-03-08 | Sony Corp | 電子部品、給電装置、受電装置、およびワイヤレス給電システム |
| KR101381604B1 (ko) * | 2010-08-31 | 2014-04-11 | 한국전자통신연구원 | 고분자 박막 및 자기비드를 이용한 바이오 물질 측정방법 |
| US20140099663A1 (en) * | 2010-11-15 | 2014-04-10 | Regents Of The University Of Minnesota | Gmr sensor |
| RU2528885C2 (ru) * | 2011-10-04 | 2014-09-20 | Общество с ограниченной ответственностью "Инноград Пущино" | Способ детекции аналита из раствора на частицах и устройство для его реализации |
| DE102013109467A1 (de) * | 2013-08-30 | 2015-03-05 | MRB Forschungszentrum für Magnet - Resonanz - Bayern e.V. | Verfahren und Vorrichtung zur Analyse eines magnetische Partikel umfassenden Probenvolumens |
| RU2539828C1 (ru) * | 2013-11-08 | 2015-01-27 | Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Национальный исследовательский технологический университет "МИСиС" | Спектральный эллипсометр с устройством магнитодинамических измерений |
| RU2544276C1 (ru) * | 2013-11-08 | 2015-03-20 | Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Национальный исследовательский технологический университет "МИСиС" | Способ измерения параметров наноразмерных магнитных пленок |
| FR3038063B1 (fr) * | 2015-06-26 | 2018-10-26 | Atware | Appareil pour mesurer un champ magnetique |
| RU2016138725A (ru) * | 2016-09-30 | 2018-04-02 | Петр Иванович Никитин | Способ мультиплексного анализа с помощью магнитных меток и устройство для его осуществления |
| RU2642055C1 (ru) * | 2017-07-12 | 2018-01-23 | Общество с ограниченной ответственностью "Онико-М" | Способ селективного анализа на основе иммунологических реакций с использованием биочипов |
| US10901051B2 (en) | 2017-08-15 | 2021-01-26 | Uchicago Argonne, Llc | Ferromagnetic particles as ultra-sensitive non-linear response labels for magnetic particles imaging (MPI) and sensing applications |
| CN107831456B (zh) * | 2017-11-29 | 2024-05-03 | 武汉智能装备工业技术研究院有限公司 | 一种基于霍尔传感器的无线三轴磁场测量仪 |
| US11585882B2 (en) | 2018-04-11 | 2023-02-21 | Mars Sciences Limited | Superparamagnetic particle imaging and its applications in quantitative multiplex stationary phase diagnostic assays |
| US11366050B1 (en) | 2019-01-29 | 2022-06-21 | Dmitri Litvinov | Ultra-sensitive volumetric magnetic particle detector |
| FR3100616B1 (fr) | 2019-09-06 | 2021-09-17 | Magnisense Se | Dispositif de mesure comportant un générateur de champ magnétique et procédé de mesure associé |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US120897A (en) | 1871-11-14 | Improvement in fur-set boxes | ||
| US4247406A (en) * | 1979-04-23 | 1981-01-27 | Widder Kenneth J | Intravascularly-administrable, magnetically-localizable biodegradable carrier |
| US4712560A (en) * | 1985-08-09 | 1987-12-15 | General Electric Company | Apparatus and method of acquiring physiological gating signals for magnetic resonance imaging of moving objects |
| US4710752A (en) * | 1986-08-08 | 1987-12-01 | Pitney Bowes Inc. | Apparatus and method for detecting a magnetic marker |
| JPS63108264A (ja) * | 1986-10-25 | 1988-05-13 | Nippon Telegr & Teleph Corp <Ntt> | 磁気免疫測定方法および該方法を実施するために使用する検査試薬片 |
| JP2620082B2 (ja) * | 1987-06-23 | 1997-06-11 | 新明和工業株式会社 | ごみ容器搬送システム |
| US5164297A (en) * | 1990-05-03 | 1992-11-17 | Advanced Magnetics Inc. | Solvent mediated relaxation assay system |
| US5083112A (en) * | 1990-06-01 | 1992-01-21 | Minnesota Mining And Manufacturing Company | Multi-layer thin-film eas marker |
| JPH05264556A (ja) * | 1992-03-17 | 1993-10-12 | Fujikura Ltd | 磁気測定装置用試料台 |
| RU2092853C1 (ru) * | 1992-10-12 | 1997-10-10 | Александр Георгиевич Полтавченко | Иммунодиагностикум и способ твердофазного иммуноанализа на его основе |
| ATE156706T1 (de) | 1993-03-17 | 1997-08-15 | Silica Gel Gmbh | Superparamagnetische teilchen, verfahren zu ihrer herstellung und verwendung derselben |
| CH686518A5 (de) * | 1993-10-05 | 1996-04-15 | Asahi Optical Co Ltd | Granulares Polymerkomposit, Herstellungsverfahren fur dieses und diagnostische Mittel. |
| RU2082982C1 (ru) * | 1994-02-25 | 1997-06-27 | Государственный научно-исследовательский институт биологического приборостроения | Способ твердофазного люминесцентного иммуноанализа компонентов биологических жидкостей |
| EP0772776B1 (de) | 1994-07-27 | 2000-03-22 | Herbert Dr. Pilgrimm | Superparamagnetische teilchen, verfahren zur herstellung und deren verwendung |
| US5656429A (en) * | 1994-10-03 | 1997-08-12 | Adelman; Lonnie W. | Polynucleotide and protein analysis method using magnetizable moieties |
| DE19503664C2 (de) * | 1995-01-27 | 1998-04-02 | Schering Ag | Magnetorelaxometrische Detektion von Analyten |
| US5614824A (en) * | 1995-05-15 | 1997-03-25 | Crane & Co., Inc. | Harmonic-based verifier device for a magnetic security thread having linear and non-linear ferromagnetic characteristics |
| JP2965131B2 (ja) | 1995-07-07 | 1999-10-18 | 東洋紡績株式会社 | 核酸結合用磁性担体およびそれを用いる核酸単離方法 |
| US5608316A (en) * | 1995-08-21 | 1997-03-04 | Caterpillar Inc. | Apparatus for detecting particles in a fluid and a method for operating same |
| FR2749082B1 (fr) | 1996-05-24 | 1998-06-26 | Bio Merieux | Particules superparamagnetiques et monodispersees |
| US6057167A (en) * | 1996-05-31 | 2000-05-02 | Motorola, Inc. | Magnetoresistance-based method and apparatus for molecular detection |
| US6437563B1 (en) * | 1997-11-21 | 2002-08-20 | Quantum Design, Inc. | Method and apparatus for making measurements of accumulations of magnetically susceptible particles combined with analytes |
| US6046585A (en) * | 1997-11-21 | 2000-04-04 | Quantum Design, Inc. | Method and apparatus for making quantitative measurements of localized accumulations of target particles having magnetic particles bound thereto |
| DE19822123C2 (de) * | 1997-11-21 | 2003-02-06 | Meinhard Knoll | Verfahren und Vorrichtung zum Nachweis von Analyten |
| JP2000056032A (ja) * | 1998-08-06 | 2000-02-25 | Nippon System Square:Kk | 金属検出装置 |
-
2000
- 2000-03-09 RU RU2000105511/28A patent/RU2166751C1/ru active
-
2001
- 2001-03-07 AU AU2001248937A patent/AU2001248937A1/en not_active Abandoned
- 2001-03-07 EP EP09169524A patent/EP2120041B1/de not_active Expired - Lifetime
- 2001-03-07 WO PCT/RU2001/000100 patent/WO2001067062A2/ru not_active Ceased
- 2001-03-07 US US10/221,107 patent/US7785902B2/en active Active
- 2001-03-07 AT AT01922159T patent/ATE448479T1/de not_active IP Right Cessation
- 2001-03-07 DE DE60140431T patent/DE60140431D1/de not_active Expired - Lifetime
- 2001-03-07 ES ES01922159T patent/ES2333517T3/es not_active Expired - Lifetime
- 2001-03-07 EP EP01922159A patent/EP1262766B1/de not_active Expired - Lifetime
- 2001-03-07 ES ES09169524T patent/ES2407122T3/es not_active Expired - Lifetime
- 2001-03-07 JP JP2001565986A patent/JP4817581B2/ja not_active Expired - Lifetime
-
2008
- 2008-04-08 US US12/078,953 patent/US7732220B2/en not_active Expired - Fee Related
-
2010
- 2010-03-11 US US12/722,255 patent/US8865068B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| RU2166751C1 (ru) | 2001-05-10 |
| WO2001067062A3 (fr) | 2002-04-11 |
| ES2407122T3 (es) | 2013-06-11 |
| US7785902B2 (en) | 2010-08-31 |
| EP1262766B1 (de) | 2009-11-11 |
| JP2003526104A (ja) | 2003-09-02 |
| US7732220B2 (en) | 2010-06-08 |
| JP4817581B2 (ja) | 2011-11-16 |
| ES2333517T3 (es) | 2010-02-23 |
| EP2120041A2 (de) | 2009-11-18 |
| DE60140431D1 (de) | 2009-12-24 |
| US20030027197A1 (en) | 2003-02-06 |
| US8865068B2 (en) | 2014-10-21 |
| WO2001067062A2 (fr) | 2001-09-13 |
| US20080261329A1 (en) | 2008-10-23 |
| EP2120041B1 (de) | 2013-02-27 |
| EP2120041A3 (de) | 2010-10-20 |
| AU2001248937A1 (en) | 2001-09-17 |
| US20100209299A1 (en) | 2010-08-19 |
| EP1262766A2 (de) | 2002-12-04 |
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